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The map label for this gene is cobW [H]

Identifier: 158422625

GI number: 158422625

Start: 1119481

End: 1120659

Strand: Reverse

Name: cobW [H]

Synonym: AZC_1001

Alternate gene names: 158422625

Gene position: 1120659-1119481 (Counterclockwise)

Preceding gene: 158422626

Following gene: 158422622

Centisome position: 20.87

GC content: 69.72

Gene sequence:

>1179_bases
GTGAGCCCTTTCGAGACGCCGGAGGCCGGCACGGCCCCGGACCGGCCCGCCCGTCGCGGTCCGCCCGAGCCCATTCCCGT
CACCGTGCTCACGGGCTTTCTCGGCGCGGGCAAGACGACGCTCCTCAACCGTATCCTCGCCGATACAGCGCTGGCCGACA
CCGCCGTCCTCATCAATGAGTTCGGCGAGATCGGCCTTGACCATCTGTTCGTGCGCGAGGTGGACGAGGGCGTGGTGCTG
CTGGCCAGCGGCTGCGTCTGCTGCACCGTGCGCGGCGACCTTGTGGCGGCGCTGGAAGACCTGCTGCGCGGGCGCGACAA
CAACCGTCTGCCGCCCTTCTCCCGCGTGCTGATCGAGACCACGGGCCTTGCCGACCCGGCGCCCATCCTCCACACGCTGA
TGACCCACCCCTATCTGCTGATGCGGTATCGGCTGGACGGGGTGGTGACGGTGGTGGACGCCATCAATGGCGGCGCGACC
CTCGACGCGCAGCCCGAGGCGGTGAAGCAGGCAGCCGTCTCCGATCGCATCGTCCTCACCAAGACGGACCTCGCACAGAC
GGACGCGGAGAAAACCGCCGTTGCCGACTTGCGGCGGCGCCTCGCGACGCTCGCCCCGGCTGCGCCCGTTCTGGATGCGG
CGGCGGGGGAAGCGACCGCTGAGCGCATCCTCAAGGCGGGTCTCTATGACCCGGCGCGCAAGATTCCCGACGTGGCCCGC
TGGCTGGCGGAGGAGCAGATCGCCGCCAATCGCGAGGCGGCCGAGGGGCCGGCGGTAGTCACCGATCCCAACCGGCACGA
CGACCGCATCAAGGCCTTTTCGCTCGCCACCGATGCCGCAATTCCCGCCTCGACGCTGGACCTGTTCCTTGAGCTGCTGC
GGGCCACCCACGGCGGCAGCGTTCTGCGCATGAAAGGCATCGTGAAGCTGGCGGACGATCCCTCCGCCCCGGTGGTGCTG
CACGGCGTCCAGCATGTGATGCATCCGCCGAGCCGCCTTGCCGCATGGCCCGATGACGACCACCGCACGCGTCTCGTCAT
GATCGTGCGGGACCTTGACCCGATGGTGATCCAGCGCCTGTTCGAGGCCTTCCTTGGTGTGCCCTCGGTGGACACGCCGG
ACCGGGCGGCGATGACGGACAACCCCCTCGCCCCGCCCGGCCTCTCTGGCATGCGCTGA

Upstream 100 bases:

>100_bases
GAGCGCCGACAAGCCGAAGCCCAAGACGCAAGGCAATGGGCAGGATGACAGCGCCCCGGCGCAGAAGCCCGGCGGCTGAC
GCCCTTTCGAGAGACAGATC

Downstream 100 bases:

>100_bases
CCGCTCAGCCGATGCCGTGATCCGGCAAGGAGAGGTTGTCGGCGGTGAGATCCGCCACATGCACGCCTTGCAGGATGATA
CCGATGGGCCAGTGCAGGTC

Product: CobW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINEFGEIGLDHLFVREVDEGVVL
LASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIETTGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGAT
LDAQPEAVKQAAVSDRIVLTKTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVAR
WLAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGSVLRMKGIVKLADDPSAPVVL
HGVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRLFEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR

Sequences:

>Translated_392_residues
MSPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINEFGEIGLDHLFVREVDEGVVL
LASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIETTGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGAT
LDAQPEAVKQAAVSDRIVLTKTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVAR
WLAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGSVLRMKGIVKLADDPSAPVVL
HGVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRLFEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR
>Mature_391_residues
SPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINEFGEIGLDHLFVREVDEGVVLL
ASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIETTGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGATL
DAQPEAVKQAAVSDRIVLTKTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVARW
LAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGSVLRMKGIVKLADDPSAPVVLH
GVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRLFEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=382, Percent_Identity=29.0575916230367, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI126722884, Length=382, Percent_Identity=29.0575916230367, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI148727351, Length=382, Percent_Identity=29.0575916230367, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI146231952, Length=382, Percent_Identity=29.3193717277487, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI223941779, Length=382, Percent_Identity=28.5340314136126, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI223941776, Length=348, Percent_Identity=28.448275862069, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI119120938, Length=375, Percent_Identity=27.2, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI87082430, Length=325, Percent_Identity=32.9230769230769, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788499, Length=168, Percent_Identity=34.5238095238095, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=264, Percent_Identity=28.030303030303, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41931; Mature: 41799

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGEIGLDHLFVREVDEGVVLLASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIET
HHHHCHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGATLDAQPEAVKQAAVSDRIVLT
CCCCCHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
KTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVAR
ECCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
WLAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGS
HHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
VLRMKGIVKLADDPSAPVVLHGVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRL
EEEEECEEEECCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHH
FEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGEIGLDHLFVREVDEGVVLLASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIET
HHHHCHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGATLDAQPEAVKQAAVSDRIVLT
CCCCCHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
KTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVAR
ECCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
WLAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGS
HHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
VLRMKGIVKLADDPSAPVVLHGVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRL
EEEEECEEEECCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHH
FEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]