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The map label for this gene is pcaI [H]

Identifier: 158422618

GI number: 158422618

Start: 1111514

End: 1112224

Strand: Direct

Name: pcaI [H]

Synonym: AZC_0994

Alternate gene names: 158422618

Gene position: 1111514-1112224 (Clockwise)

Preceding gene: 158422610

Following gene: 158422619

Centisome position: 20.7

GC content: 67.51

Gene sequence:

>711_bases
ATGGACAAGACGGTCGGGGATCTCGCCACGGCGGTTTCCGAGATCGGGGATGGCGCCACGGTGATGATCGGCGGCTTCGG
CGGCGCCGGTGCGCCGGTGGAGCTCATCCACGCCCTCATCGACAAGGGGCCGAAGGGCCTCACCGTGGTCAACAACAATG
CGGGCAACGGGCGCATCGGCATCGCCGCGATGATCGCGGCCGGCATGGTGCGCAAGCTGATCTGCTCCTTCCCCCGCGCG
GCGGACGCCAGCGCCTTCAACGAGCGCTATCTGGCGGGTGAACTGGAGCTGGAACTGGTGCCGCAGGGCACGCTCGCCGA
GCGCATCCGCGCCGGCGGTGCGGGCATTCCAGCCTTCTACACGCCCACCAGCTATGGCACCGAACTCGCCGAGGGCAAGC
CGGTGGCCGAGTTTGACGGGCGGCCCTATGTGCAGGAGCGCTGGCTGAAGGCGGACTTCGCCCTCGTGAAAGCCCATCTC
GGCGATCCCTACGGCAACCTCACCTACAACAAGGCGGCCCGCAACTTCAGCCCGCTGATGTGCATGGCAGCGGCCAAGAC
CATCGTGCAGGTCTCGCGCATCGTGCCGCCGGGCGACATCGATCCCGAGCACGTCATCACACCCGGCATCTTCGTGGACC
GGGTGGTCGAGGTCGCCGATGCGCGACAGGAAGAGGACCTCATCCGGGCGGGAGCGGCCTACAATGACTGA

Upstream 100 bases:

>100_bases
TATCGCACAAATGCCTTGCTGTCGATAGGGACCGGGCCTATCCGTTCCTCAGGGCCAGAGTGCCGGTCAGGCGCGGCCCG
TGAGTTCCGGGAGGACCTGC

Downstream 100 bases:

>100_bases
GACCCTTCAGAACGACGGCAAGCTGTCGAACGCCCAGATTGCCTGGCGCGCGGCGCAGGACATTGCCGATGGCGCCTATG
TGAACCTCGGCATCGGCTTC

Product: 3-oxoadipate CoA-transferase, subunit alpha

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIGIAAMIAAGMVRKLICSFPRA
ADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFYTPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHL
GDPYGNLTYNKAARNFSPLMCMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND

Sequences:

>Translated_236_residues
MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIGIAAMIAAGMVRKLICSFPRA
ADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFYTPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHL
GDPYGNLTYNKAARNFSPLMCMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND
>Mature_236_residues
MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIGIAAMIAAGMVRKLICSFPRA
ADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFYTPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHL
GDPYGNLTYNKAARNFSPLMCMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=44.9392712550607, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=46.7811158798283, Blast_Score=184, Evalue=4e-47,
Organism=Escherichia coli, GI1788551, Length=206, Percent_Identity=42.2330097087379, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787985, Length=244, Percent_Identity=27.0491803278689, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531517, Length=226, Percent_Identity=44.2477876106195, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21358325, Length=237, Percent_Identity=44.3037974683544, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24655794, Length=237, Percent_Identity=44.3037974683544, Blast_Score=197, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24841; Mature: 24841

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIG
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHH
IAAMIAAGMVRKLICSFPRAADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFY
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCEEEEECCCCHHHHHHHCCCCCCCCEE
TPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHLGDPYGNLTYNKAARNFSPLM
CCCCCCCHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
CMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND
HHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIG
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHH
IAAMIAAGMVRKLICSFPRAADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFY
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCEEEEECCCCHHHHHHHCCCCCCCCEE
TPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHLGDPYGNLTYNKAARNFSPLM
CCCCCCCHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
CMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND
HHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]