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The map label for this gene is adiA [H]

Identifier: 158422607

GI number: 158422607

Start: 1095282

End: 1097546

Strand: Reverse

Name: adiA [H]

Synonym: AZC_0983

Alternate gene names: 158422607

Gene position: 1097546-1095282 (Counterclockwise)

Preceding gene: 158422611

Following gene: 158422606

Centisome position: 20.44

GC content: 67.15

Gene sequence:

>2265_bases
ATGAAGGCCCTCGTCGTCGACGACGAGATTGCACTTGAAACGGCTGCGGGCCGCGCGCTGCGGGGACTGGTGGCGGAACT
GGAGCGGCGGGACATCCGCATCGTCACCGCCGCCACCTCGTCAGACGCCATCGCCATCGTCGGCTCGGACCCGGCCCTGC
AATGCGTCCTGCTGGACTGGGATCTCGGGCCGGATGGCCATGCCCCGGCTATCGCGGTCCTTGAAACGCTGCGCGCGCGC
AACCATACGGTCCCCGTGTTCCTGCTGGCGGACCGCAGCGTCGCATCCACCGTGCCGGCGAAGGTCATGGCGCAGGTGGA
CGATTTCGTCTGGCTGCTGGAAGACACCATCGACTTCGTCGGCGGGCGCGTCGAGGCGGCCGTGGAGCGCTACCGCGCGA
CCGTGCTCCCGCCCATGTTCGGCGCCTTGGTCAAGTTCGCGCGGGTGCATGAATATTCCTGGCACACGCCGGGCCACACG
GGCGGAACGGCCTTCCTGAAATCCCCGCCCGGCCGCGCCTTCTTCGAGTTCTTCGGCGAGCCCCTGCTGCGCTCCGACCT
CTCCATCTCGGTGGGTGAGCTTGGCTCGCTGCTGGACCATTCCGGTCCCATCGGCGCAAGCGAGAAATACGCCGCGCGCG
TCTTCGGCTCCCACCGCACCTATCACGTCACCAACGGCTCCTCCACCTCCAACCGCGTCATCCTGATGGCGAGCGTGAGC
CGCGACCAGATCGCCCTGTGCGACCGCAACTGCCACAAGTCCGCCGAGCACGCGATGACCATGTCCGGCGCCGTGCCGAC
CTATCTGGTGCCGACCCGCAACCATTACGGCATCATCGGCCCCATTCCGCCCGAGCGGCTGACGACGGCGGCGGTGCGCC
AGGCCATCGAGGCCAATCCGCTGACCGCAGGCCTGGCAGATCGGATACCTAAGCACGCGATCATCACAAACTCCACCTAT
GACGGCCTGTGCTACAACGTCTCCCGCGTGGAGGAACTGCTGGGTGGCAGCGTGGACCGGCTGCATTTCGACGAGGCGTG
GTACGGCTACGCGCGCTTCAATCCCCTCTATCGAGACCGCCATGCCATGCATGGCGATCCGTCGGCCCATGGCGCGGACA
AGCCGACGGTCTTCGCCACCCAGTCCACGCACAAGCTGCTGGCGGCGCTGTCTCAGGCCTCCTTCATCCACGTGCGCGAC
GGGCGCCGCCCGATCCCGCACTGCATCTTCAACGAGACGTTCATGATGCACGCCTCGACTTCGCCGCTCTATCCCATCAT
CGCCTCCAACGACGTGTCGGCGGCGATGATGGATGGTCCCGGCGGCGCGGCGCTGACGGGTGAGTCCATCGCCGAGGCCG
TCGCCTTCCGGCAGATGATGTCGCGTCTCGCCAATGAGGCGGCCGAGCAGGGCGACTGGTTCTTCGACTGCTGGCAGCCG
GACACGGTGCGCGACCCGAAGACCGGGCGCGTGACCCCCTTCCACGAGGCATCGCCGGAAGCGCTCGCCACCGATCCGTC
CTGCTGGGTGCTGAAGCCGGACGCCCAGTGGCACGGCTTCGGCGCCATCGAGGACGGCTATTGCATGCTCGACCCCATCA
AGGTCTCGGTGGTGACGCCGGGCGTCGCGCCGGGCGGCGGACTGATGCCCGTGGGCATTCCCGCAAGCCTCGTCACCGCC
TATCTCGATGCCCGCGGCATCGTGGTGGAGAAGACCACGGACTTCACCATCCTGTTCCTGTTCTCGCTGGGCATCACCAA
GGGCAAATGGGGCTCGCTCGTCAGCGCCCTGTGCGACTTCAAGCGGGACTACGACGCCAACCTGCCCATCGAACTCGCTA
TTCCGCCGCTCGCTGAAACCACCGGCGACCGCTATCTCGGCCTGGGCCTGAAGGATCTGGCGGACACCATGTTCGCGGCC
ATGGACGAACTGAAGACCACCGCCATGATGGCGCAGGCCTTCTCCCTCCTGCCGCATCCCGATTTCAGCCCCGTGCAGGC
CTATGAGCGGCTGGTCCAGGGGCAGGTGGAACAGGTGACGCTGGACGAACTCGCCGGCCATACGGTCGCGACCGGCGTGG
TGCCCTACCCGCCCGGCATCCCGCTCTTGATGCCCGGCGAGAATGCCGGCCCGGCAGATGGCCCCGTGCTCGGCTATCTC
AAGGCGCTGGAAGCCTATGACCTGCGCTTCCCCGGCTTTGCCCACGACACGCACGGCGTGGAGGTGGAGGACGGGCGCTA
TCTCATCCACCGCATCGTGCGCTGA

Upstream 100 bases:

>100_bases
GCTCCGTCGGGCGCAGGCCCCTCCGGGCGCCGAGCTCTTGCGCCCCACCTCCGAGGACATCGTCATGAGCACGCCCACCA
AAGCGCATCATCGCCTCGGC

Downstream 100 bases:

>100_bases
GGGGCTGCGAGCATGTCCTCCACCGACACCGCCCCTGCCGCTTCCACCGACGCCGAGGCCGCAAAGATCGGCCTCGTGCC
GGCGACCCTGATGGTCGCCG

Product: Orn/Lys/Arg decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MKALVVDDEIALETAAGRALRGLVAELERRDIRIVTAATSSDAIAIVGSDPALQCVLLDWDLGPDGHAPAIAVLETLRAR
NHTVPVFLLADRSVASTVPAKVMAQVDDFVWLLEDTIDFVGGRVEAAVERYRATVLPPMFGALVKFARVHEYSWHTPGHT
GGTAFLKSPPGRAFFEFFGEPLLRSDLSISVGELGSLLDHSGPIGASEKYAARVFGSHRTYHVTNGSSTSNRVILMASVS
RDQIALCDRNCHKSAEHAMTMSGAVPTYLVPTRNHYGIIGPIPPERLTTAAVRQAIEANPLTAGLADRIPKHAIITNSTY
DGLCYNVSRVEELLGGSVDRLHFDEAWYGYARFNPLYRDRHAMHGDPSAHGADKPTVFATQSTHKLLAALSQASFIHVRD
GRRPIPHCIFNETFMMHASTSPLYPIIASNDVSAAMMDGPGGAALTGESIAEAVAFRQMMSRLANEAAEQGDWFFDCWQP
DTVRDPKTGRVTPFHEASPEALATDPSCWVLKPDAQWHGFGAIEDGYCMLDPIKVSVVTPGVAPGGGLMPVGIPASLVTA
YLDARGIVVEKTTDFTILFLFSLGITKGKWGSLVSALCDFKRDYDANLPIELAIPPLAETTGDRYLGLGLKDLADTMFAA
MDELKTTAMMAQAFSLLPHPDFSPVQAYERLVQGQVEQVTLDELAGHTVATGVVPYPPGIPLLMPGENAGPADGPVLGYL
KALEAYDLRFPGFAHDTHGVEVEDGRYLIHRIVR

Sequences:

>Translated_754_residues
MKALVVDDEIALETAAGRALRGLVAELERRDIRIVTAATSSDAIAIVGSDPALQCVLLDWDLGPDGHAPAIAVLETLRAR
NHTVPVFLLADRSVASTVPAKVMAQVDDFVWLLEDTIDFVGGRVEAAVERYRATVLPPMFGALVKFARVHEYSWHTPGHT
GGTAFLKSPPGRAFFEFFGEPLLRSDLSISVGELGSLLDHSGPIGASEKYAARVFGSHRTYHVTNGSSTSNRVILMASVS
RDQIALCDRNCHKSAEHAMTMSGAVPTYLVPTRNHYGIIGPIPPERLTTAAVRQAIEANPLTAGLADRIPKHAIITNSTY
DGLCYNVSRVEELLGGSVDRLHFDEAWYGYARFNPLYRDRHAMHGDPSAHGADKPTVFATQSTHKLLAALSQASFIHVRD
GRRPIPHCIFNETFMMHASTSPLYPIIASNDVSAAMMDGPGGAALTGESIAEAVAFRQMMSRLANEAAEQGDWFFDCWQP
DTVRDPKTGRVTPFHEASPEALATDPSCWVLKPDAQWHGFGAIEDGYCMLDPIKVSVVTPGVAPGGGLMPVGIPASLVTA
YLDARGIVVEKTTDFTILFLFSLGITKGKWGSLVSALCDFKRDYDANLPIELAIPPLAETTGDRYLGLGLKDLADTMFAA
MDELKTTAMMAQAFSLLPHPDFSPVQAYERLVQGQVEQVTLDELAGHTVATGVVPYPPGIPLLMPGENAGPADGPVLGYL
KALEAYDLRFPGFAHDTHGVEVEDGRYLIHRIVR
>Mature_754_residues
MKALVVDDEIALETAAGRALRGLVAELERRDIRIVTAATSSDAIAIVGSDPALQCVLLDWDLGPDGHAPAIAVLETLRAR
NHTVPVFLLADRSVASTVPAKVMAQVDDFVWLLEDTIDFVGGRVEAAVERYRATVLPPMFGALVKFARVHEYSWHTPGHT
GGTAFLKSPPGRAFFEFFGEPLLRSDLSISVGELGSLLDHSGPIGASEKYAARVFGSHRTYHVTNGSSTSNRVILMASVS
RDQIALCDRNCHKSAEHAMTMSGAVPTYLVPTRNHYGIIGPIPPERLTTAAVRQAIEANPLTAGLADRIPKHAIITNSTY
DGLCYNVSRVEELLGGSVDRLHFDEAWYGYARFNPLYRDRHAMHGDPSAHGADKPTVFATQSTHKLLAALSQASFIHVRD
GRRPIPHCIFNETFMMHASTSPLYPIIASNDVSAAMMDGPGGAALTGESIAEAVAFRQMMSRLANEAAEQGDWFFDCWQP
DTVRDPKTGRVTPFHEASPEALATDPSCWVLKPDAQWHGFGAIEDGYCMLDPIKVSVVTPGVAPGGGLMPVGIPASLVTA
YLDARGIVVEKTTDFTILFLFSLGITKGKWGSLVSALCDFKRDYDANLPIELAIPPLAETTGDRYLGLGLKDLADTMFAA
MDELKTTAMMAQAFSLLPHPDFSPVQAYERLVQGQVEQVTLDELAGHTVATGVVPYPPGIPLLMPGENAGPADGPVLGYL
KALEAYDLRFPGFAHDTHGVEVEDGRYLIHRIVR

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=752, Percent_Identity=48.0053191489362, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI1790573, Length=732, Percent_Identity=39.6174863387978, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1786384, Length=739, Percent_Identity=37.6184032476319, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1786909, Length=685, Percent_Identity=32.2627737226277, Blast_Score=343, Evalue=3e-95,
Organism=Escherichia coli, GI87082193, Length=687, Percent_Identity=33.0422125181951, Blast_Score=331, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 81538; Mature: 81538

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVVDDEIALETAAGRALRGLVAELERRDIRIVTAATSSDAIAIVGSDPALQCVLLDW
CCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCEEEEEEEE
DLGPDGHAPAIAVLETLRARNHTVPVFLLADRSVASTVPAKVMAQVDDFVWLLEDTIDFV
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGRVEAAVERYRATVLPPMFGALVKFARVHEYSWHTPGHTGGTAFLKSPPGRAFFEFFGE
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHCC
PLLRSDLSISVGELGSLLDHSGPIGASEKYAARVFGSHRTYHVTNGSSTSNRVILMASVS
HHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECC
RDQIALCDRNCHKSAEHAMTMSGAVPTYLVPTRNHYGIIGPIPPERLTTAAVRQAIEANP
CCCEEECCCHHHHHHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCC
LTAGLADRIPKHAIITNSTYDGLCYNVSRVEELLGGSVDRLHFDEAWYGYARFNPLYRDR
CCCCHHHHCCCCEEEECCCCCCCEECHHHHHHHHCCCCCEEEECCHHCCHHHCCCHHHHC
HAMHGDPSAHGADKPTVFATQSTHKLLAALSQASFIHVRDGRRPIPHCIFNETFMMHAST
CCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCCCCCHHHCCCEEEEEECC
SPLYPIIASNDVSAAMMDGPGGAALTGESIAEAVAFRQMMSRLANEAAEQGDWFFDCWQP
CCCEEEEECCCCCEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
DTVRDPKTGRVTPFHEASPEALATDPSCWVLKPDAQWHGFGAIEDGYCMLDPIKVSVVTP
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEEEC
GVAPGGGLMPVGIPASLVTAYLDARGIVVEKTTDFTILFLFSLGITKGKWGSLVSALCDF
CCCCCCCEEECCCCHHHHHHHHCCCCEEEECCCCEEEEEEEHHCCCCCCHHHHHHHHHHH
KRDYDANLPIELAIPPLAETTGDRYLGLGLKDLADTMFAAMDELKTTAMMAQAFSLLPHP
HCCCCCCCCEEEECCCCHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFSPVQAYERLVQGQVEQVTLDELAGHTVATGVVPYPPGIPLLMPGENAGPADGPVLGYL
CCCHHHHHHHHHCCCHHEEEHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHH
KALEAYDLRFPGFAHDTHGVEVEDGRYLIHRIVR
HHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHCC
>Mature Secondary Structure
MKALVVDDEIALETAAGRALRGLVAELERRDIRIVTAATSSDAIAIVGSDPALQCVLLDW
CCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCEEEEEEEE
DLGPDGHAPAIAVLETLRARNHTVPVFLLADRSVASTVPAKVMAQVDDFVWLLEDTIDFV
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGRVEAAVERYRATVLPPMFGALVKFARVHEYSWHTPGHTGGTAFLKSPPGRAFFEFFGE
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHCC
PLLRSDLSISVGELGSLLDHSGPIGASEKYAARVFGSHRTYHVTNGSSTSNRVILMASVS
HHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECC
RDQIALCDRNCHKSAEHAMTMSGAVPTYLVPTRNHYGIIGPIPPERLTTAAVRQAIEANP
CCCEEECCCHHHHHHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCC
LTAGLADRIPKHAIITNSTYDGLCYNVSRVEELLGGSVDRLHFDEAWYGYARFNPLYRDR
CCCCHHHHCCCCEEEECCCCCCCEECHHHHHHHHCCCCCEEEECCHHCCHHHCCCHHHHC
HAMHGDPSAHGADKPTVFATQSTHKLLAALSQASFIHVRDGRRPIPHCIFNETFMMHAST
CCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCCCCCHHHCCCEEEEEECC
SPLYPIIASNDVSAAMMDGPGGAALTGESIAEAVAFRQMMSRLANEAAEQGDWFFDCWQP
CCCEEEEECCCCCEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
DTVRDPKTGRVTPFHEASPEALATDPSCWVLKPDAQWHGFGAIEDGYCMLDPIKVSVVTP
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEEEC
GVAPGGGLMPVGIPASLVTAYLDARGIVVEKTTDFTILFLFSLGITKGKWGSLVSALCDF
CCCCCCCEEECCCCHHHHHHHHCCCCEEEECCCCEEEEEEEHHCCCCCCHHHHHHHHHHH
KRDYDANLPIELAIPPLAETTGDRYLGLGLKDLADTMFAAMDELKTTAMMAQAFSLLPHP
HCCCCCCCCEEEECCCCHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFSPVQAYERLVQGQVEQVTLDELAGHTVATGVVPYPPGIPLLMPGENAGPADGPVLGYL
CCCHHHHHHHHHCCCHHEEEHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHH
KALEAYDLRFPGFAHDTHGVEVEDGRYLIHRIVR
HHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]