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The map label for this gene is 158422088

Identifier: 158422088

GI number: 158422088

Start: 519317

End: 520378

Strand: Reverse

Name: 158422088

Synonym: AZC_0464

Alternate gene names: NA

Gene position: 520378-519317 (Counterclockwise)

Preceding gene: 158422097

Following gene: 158422086

Centisome position: 9.69

GC content: 67.89

Gene sequence:

>1062_bases
ATGAAGGTGTGCATCTATGGGGCAGGGGCCATCGGCGGCTATCTCGGCGTTCAGCTGGCCAATGCCGGCGCGGAGGTCAG
CCTCGTGGCGCGTGGTGCCCATCTCGAAGCCATGCGGCAGAACGGCGTGAAGCTCCTCATCAACGGGGAAGAGCGCGTCG
CCCGCGTGAACGCCAGCGATGATCCGGCGGAGCTCGGCCCGCAGGATTACGTCTTCATCTCCCTCAAGGCCCATTCCGTC
CCCGGCGTGGTGGAGCGCATGCGCCCCCTGCTCGGCAACGACACCAGCGTCGTCACCGCCGTCAACGGCGTGCCCTACTG
GTATTTCTACAAGCACGGCGGGCCGCTGGAAGGCCGGACGCTGGAGAGCATCGATCCGGGTGGAAAGCAGTGGGACGTGC
TGCGCCCCGAGCGCGCCATCGGCTGCATCGTCTATCCCGCCACCGAAGTGGTGGAGCCCGGCGTCATCCAGCACATCTAC
GGCGACAAGTTCCCCATCGGCGAGCCGTCCGGTGAGCGCACAGAGCGCATCCAGCGCCTGAGCGATCTCATGAATTCCGC
CGGCCTGCGCGCGCCGGTGGTGGATCACATCCGCGACGAGATGTGGCTGAAGCTGTGGGGCAACCTCTGCTTCAACCCCA
TCAGCGCCCTCACCAACGCCACCCTCGAAGTGATCGCCGCCGATCCGGACACCCGCTCGGTGGCCAAGGCGATGATGCTG
GAGGCACAGGAGATCGCCACCCGTCTCGGCGTGAGCTTCCGTGTGGACGTGGAGCGCCGCATCAACGGCGCCGGCGCGGT
GGGTGCGCACAAGACCTCCATGCTCCAGGATCTGGAGCGCGGGCGCCCCATGGAGATCGATCCGCTGGTGACCGTGGTTC
AGGAAATGGGCCGCATGGTGGATGTGCCCACCCCGACGCTCGACGTGGTTCTGGCCCTCGTGCGCCAGCGCGCCGCCACC
GCCGGCATCGGCGATCATCTGTCGACCCCGCCGCTCACCGCGGCCGACCTGCGGGCGGCGGACCTTCATGCCTCCACGGG
CAAGATGGCCGCGCGGCACTGA

Upstream 100 bases:

>100_bases
AATCTCACGGCTATCCTCTTATTCATCGGCTTCGAAGGCCGCGTCCGCGTCACGCGGTGGCATACAAAATATTCCATTCA
AAAGACGAGGAGACGCTGGA

Downstream 100 bases:

>100_bases
GATCTGCCGGAGGGCCTGCCCTCCGGCGACGCCTTACACCTCCAAGCCAACTGCGCCGGCACTCCTTCGGGGGGCCGGCG
TTCTTTTTGGTCCGGGAGGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKVCIYGAGAIGGYLGVQLANAGAEVSLVARGAHLEAMRQNGVKLLINGEERVARVNASDDPAELGPQDYVFISLKAHSV
PGVVERMRPLLGNDTSVVTAVNGVPYWYFYKHGGPLEGRTLESIDPGGKQWDVLRPERAIGCIVYPATEVVEPGVIQHIY
GDKFPIGEPSGERTERIQRLSDLMNSAGLRAPVVDHIRDEMWLKLWGNLCFNPISALTNATLEVIAADPDTRSVAKAMML
EAQEIATRLGVSFRVDVERRINGAGAVGAHKTSMLQDLERGRPMEIDPLVTVVQEMGRMVDVPTPTLDVVLALVRQRAAT
AGIGDHLSTPPLTAADLRAADLHASTGKMAARH

Sequences:

>Translated_353_residues
MKVCIYGAGAIGGYLGVQLANAGAEVSLVARGAHLEAMRQNGVKLLINGEERVARVNASDDPAELGPQDYVFISLKAHSV
PGVVERMRPLLGNDTSVVTAVNGVPYWYFYKHGGPLEGRTLESIDPGGKQWDVLRPERAIGCIVYPATEVVEPGVIQHIY
GDKFPIGEPSGERTERIQRLSDLMNSAGLRAPVVDHIRDEMWLKLWGNLCFNPISALTNATLEVIAADPDTRSVAKAMML
EAQEIATRLGVSFRVDVERRINGAGAVGAHKTSMLQDLERGRPMEIDPLVTVVQEMGRMVDVPTPTLDVVLALVRQRAAT
AGIGDHLSTPPLTAADLRAADLHASTGKMAARH
>Mature_353_residues
MKVCIYGAGAIGGYLGVQLANAGAEVSLVARGAHLEAMRQNGVKLLINGEERVARVNASDDPAELGPQDYVFISLKAHSV
PGVVERMRPLLGNDTSVVTAVNGVPYWYFYKHGGPLEGRTLESIDPGGKQWDVLRPERAIGCIVYPATEVVEPGVIQHIY
GDKFPIGEPSGERTERIQRLSDLMNSAGLRAPVVDHIRDEMWLKLWGNLCFNPISALTNATLEVIAADPDTRSVAKAMML
EAQEIATRLGVSFRVDVERRINGAGAVGAHKTSMLQDLERGRPMEIDPLVTVVQEMGRMVDVPTPTLDVVLALVRQRAAT
AGIGDHLSTPPLTAADLRAADLHASTGKMAARH

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 38060; Mature: 38060

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCIYGAGAIGGYLGVQLANAGAEVSLVARGAHLEAMRQNGVKLLINGEERVARVNASD
CEEEEEECCHHHHHHHHEEECCCCEEEEEECCHHHHHHHHCCCEEEEECHHHEEEECCCC
DPAELGPQDYVFISLKAHSVPGVVERMRPLLGNDTSVVTAVNGVPYWYFYKHGGPLEGRT
CHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCE
LESIDPGGKQWDVLRPERAIGCIVYPATEVVEPGVIQHIYGDKFPIGEPSGERTERIQRL
ECCCCCCCCEECCCCCCCCEEEEEECHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
SDLMNSAGLRAPVVDHIRDEMWLKLWGNLCFNPISALTNATLEVIAADPDTRSVAKAMML
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
EAQEIATRLGVSFRVDVERRINGAGAVGAHKTSMLQDLERGRPMEIDPLVTVVQEMGRMV
HHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEE
DVPTPTLDVVLALVRQRAATAGIGDHLSTPPLTAADLRAADLHASTGKMAARH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVCIYGAGAIGGYLGVQLANAGAEVSLVARGAHLEAMRQNGVKLLINGEERVARVNASD
CEEEEEECCHHHHHHHHEEECCCCEEEEEECCHHHHHHHHCCCEEEEECHHHEEEECCCC
DPAELGPQDYVFISLKAHSVPGVVERMRPLLGNDTSVVTAVNGVPYWYFYKHGGPLEGRT
CHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCE
LESIDPGGKQWDVLRPERAIGCIVYPATEVVEPGVIQHIYGDKFPIGEPSGERTERIQRL
ECCCCCCCCEECCCCCCCCEEEEEECHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
SDLMNSAGLRAPVVDHIRDEMWLKLWGNLCFNPISALTNATLEVIAADPDTRSVAKAMML
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
EAQEIATRLGVSFRVDVERRINGAGAVGAHKTSMLQDLERGRPMEIDPLVTVVQEMGRMV
HHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEE
DVPTPTLDVVLALVRQRAATAGIGDHLSTPPLTAADLRAADLHASTGKMAARH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]