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The map label for this gene is ywlC [H]

Identifier: 158422031

GI number: 158422031

Start: 459122

End: 460186

Strand: Reverse

Name: ywlC [H]

Synonym: AZC_0407

Alternate gene names: 158422031

Gene position: 460186-459122 (Counterclockwise)

Preceding gene: 158422032

Following gene: 158422030

Centisome position: 8.57

GC content: 74.65

Gene sequence:

>1065_bases
GTGGCCCGGCACGGCCGGTCTTCAGGCACCGGACAGATGAGCGCTTCCCCCGCCCCGCCCTCCGCTTCCCGCAGCACGCA
GGTGCTGCCGGCGACCTCGCCCGCCCGCGCCAAGGCTGCGGCAGTGGTCGCGGGGCGGCTCATCGGCGAAGGCAAGGTGG
TCGCCTTCCCCACTGAGACGGTCTATGGGCTCGGCGCCGACGCGGGCAACCCGCGGGCGGTCGCGGAAGTCTATGCCGCC
AAGGGGCGCCCGGCCTTCAACCCGCTCATTTCCCATGTGCCGGATCTTGCCGCCGCCGAGCAGCTGGGCGTGCTGAACGC
GGATGCGGTGAAGCTCGCCCGCGCCTTCTGGCCGGGGCCGCTCACCCTCGTGGTGCCCTGCCGCGACACGGATGCCATCT
GCGACCTTGCCCGCGCCGGCCTCTCCACGACGGCACTCCGGGTGCCCAACCACCCGGCCGCCCTCGCCTTCCTCGCGGCG
GCCGGACGACCCGTGGTGGGGCCGAGCGCAAATCGCTCCGGCCATGTCTCGCCCACGACGGCCGCCCATGTGATGGCCGA
TCTCGACGGCCGCATCGACGCGGTTCTGGATGCGGGGCCGACAATGGTCGGCGTCGAATCCACCATTGTCGACTGCTCCG
GCGATGAACCGCGCCTGCTGCGGCCCGGCGGACTCGCGCGCGCCGACATCGAGGCCGTGCTCGGGCGCCCCCTGCCCGAT
GCGGCGGGCGGTGATGAGGCCAAGCCTTCGGCCCCCGGCCGGCTCGCCTCCCATTACGCGCCCAACGCCACCGTGCGGCT
GGATGTGGCGGAGGTGCGGCCCGGCGAGGCTCTGCTCACCTTCGCCGGCCACCGGCCGACGGGCAGTGAGAGCGCCGCCT
TCGTCTATGACCTCTCCCCCGCCGGCGATCTCGCGGAGGCGGCGAGCCGCCTCTATGGGGCTCTGCGCGCCATCGACGCG
CGCGGCGCGGCGGGCATCGCCGTGGTGCCACTGCCCCGCGAGGGGCTGGGCGAGGCCATCGCCGACCGCCTCGGCCGCGC
TGCCGCCCCTCGCCCGCACGACTGA

Upstream 100 bases:

>100_bases
CCCGGCCGGTGACGCAAAGCACCTCCGCATCCCGGCGAGACGCCTTGACCTGACACGCCGGAGCGCCTTTAAGCCCGAGC
GCGCACGGCAACGGCCCGCC

Downstream 100 bases:

>100_bases
CAACTCCCGTCCGAGGTCTTCTTCATGAGCGACGCGCCCCCCGCCCTTGCCATCGGCCATGCCGCGCCGGAGGAGACGGA
GGCCCTTGTGGCGCTCTGGC

Product: Sua5 protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MARHGRSSGTGQMSASPAPPSASRSTQVLPATSPARAKAAAVVAGRLIGEGKVVAFPTETVYGLGADAGNPRAVAEVYAA
KGRPAFNPLISHVPDLAAAEQLGVLNADAVKLARAFWPGPLTLVVPCRDTDAICDLARAGLSTTALRVPNHPAALAFLAA
AGRPVVGPSANRSGHVSPTTAAHVMADLDGRIDAVLDAGPTMVGVESTIVDCSGDEPRLLRPGGLARADIEAVLGRPLPD
AAGGDEAKPSAPGRLASHYAPNATVRLDVAEVRPGEALLTFAGHRPTGSESAAFVYDLSPAGDLAEAASRLYGALRAIDA
RGAAGIAVVPLPREGLGEAIADRLGRAAAPRPHD

Sequences:

>Translated_354_residues
MARHGRSSGTGQMSASPAPPSASRSTQVLPATSPARAKAAAVVAGRLIGEGKVVAFPTETVYGLGADAGNPRAVAEVYAA
KGRPAFNPLISHVPDLAAAEQLGVLNADAVKLARAFWPGPLTLVVPCRDTDAICDLARAGLSTTALRVPNHPAALAFLAA
AGRPVVGPSANRSGHVSPTTAAHVMADLDGRIDAVLDAGPTMVGVESTIVDCSGDEPRLLRPGGLARADIEAVLGRPLPD
AAGGDEAKPSAPGRLASHYAPNATVRLDVAEVRPGEALLTFAGHRPTGSESAAFVYDLSPAGDLAEAASRLYGALRAIDA
RGAAGIAVVPLPREGLGEAIADRLGRAAAPRPHD
>Mature_353_residues
ARHGRSSGTGQMSASPAPPSASRSTQVLPATSPARAKAAAVVAGRLIGEGKVVAFPTETVYGLGADAGNPRAVAEVYAAK
GRPAFNPLISHVPDLAAAEQLGVLNADAVKLARAFWPGPLTLVVPCRDTDAICDLARAGLSTTALRVPNHPAALAFLAAA
GRPVVGPSANRSGHVSPTTAAHVMADLDGRIDAVLDAGPTMVGVESTIVDCSGDEPRLLRPGGLARADIEAVLGRPLPDA
AGGDEAKPSAPGRLASHYAPNATVRLDVAEVRPGEALLTFAGHRPTGSESAAFVYDLSPAGDLAEAASRLYGALRAIDAR
GAAGIAVVPLPREGLGEAIADRLGRAAAPRPHD

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=134, Percent_Identity=35.8208955223881, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=189, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=383, Percent_Identity=32.8981723237598, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI78707274, Length=179, Percent_Identity=30.1675977653631, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35749; Mature: 35618

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHGRSSGTGQMSASPAPPSASRSTQVLPATSPARAKAAAVVAGRLIGEGKVVAFPTET
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHEECCCCEEEECCCC
VYGLGADAGNPRAVAEVYAAKGRPAFNPLISHVPDLAAAEQLGVLNADAVKLARAFWPGP
EEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCC
LTLVVPCRDTDAICDLARAGLSTTALRVPNHPAALAFLAAAGRPVVGPSANRSGHVSPTT
EEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AAHVMADLDGRIDAVLDAGPTMVGVESTIVDCSGDEPRLLRPGGLARADIEAVLGRPLPD
HHHHHHHCCCCEEEEECCCCCEEECCEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCCC
AAGGDEAKPSAPGRLASHYAPNATVRLDVAEVRPGEALLTFAGHRPTGSESAAFVYDLSP
CCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCEEEEEECCC
AGDLAEAASRLYGALRAIDARGAAGIAVVPLPREGLGEAIADRLGRAAAPRPHD
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARHGRSSGTGQMSASPAPPSASRSTQVLPATSPARAKAAAVVAGRLIGEGKVVAFPTET
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHEECCCCEEEECCCC
VYGLGADAGNPRAVAEVYAAKGRPAFNPLISHVPDLAAAEQLGVLNADAVKLARAFWPGP
EEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCC
LTLVVPCRDTDAICDLARAGLSTTALRVPNHPAALAFLAAAGRPVVGPSANRSGHVSPTT
EEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AAHVMADLDGRIDAVLDAGPTMVGVESTIVDCSGDEPRLLRPGGLARADIEAVLGRPLPD
HHHHHHHCCCCEEEEECCCCCEEECCEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCCC
AAGGDEAKPSAPGRLASHYAPNATVRLDVAEVRPGEALLTFAGHRPTGSESAAFVYDLSP
CCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCEEEEEECCC
AGDLAEAASRLYGALRAIDARGAAGIAVVPLPREGLGEAIADRLGRAAAPRPHD
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]