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The map label for this gene is mcp4 [H]

Identifier: 158421990

GI number: 158421990

Start: 421223

End: 422938

Strand: Direct

Name: mcp4 [H]

Synonym: AZC_0366

Alternate gene names: 158421990

Gene position: 421223-422938 (Clockwise)

Preceding gene: 158421989

Following gene: 158421992

Centisome position: 7.84

GC content: 67.54

Gene sequence:

>1716_bases
GTGCCGCCCATGCCCCGCTTGAATCTCAAGGTTTCGCACGCCGTCGCGCTGATGGTGTTCTCCTGCGTCGCCGTCACCGC
CGCCCTGCTGATCGCTGTCGTCGCCTGGATGCTGGATGATGATGCAGCGCAAAATGCCATTAATCGCCAGAATGTTGCGA
TCCGTGCTGCAGCAATCGCGCTGGCCAAGGCCGTGCCCGGCAGCCGGATCGACTGGTCCGGCAATACCGTGAGCCGCATC
GTGCTGCCGCGCCTGCCGGAGCCCGGTGACCATGGCCTCATCGATGATGTCTCTCGCATCTCCGGCGGCACGGCCACGGT
GTTCGCGTATGACGCCGGCAAGGACGATTTCGTGCGCCTCTCCACCTCCGTGAAGAAGGCCGATGGCACGCGGGCCGTGG
GCACGGTCCTCGGCCGCCAGTCCGCGGCCTATCCGGCCATGAAGGCGGGCACCATCTATCGTGGCGAGGCCACCATTCTC
GATGTGCCCTATTACACGGTCTATCTGCCGGTGTTCGATCCGTCCGGCTCGGTCATCGGCGTGGTCTATGGTGGCGTGAA
GCAGGATGAGGTGGATGCGCGCCTCAACTCCCTGCTCCGCACCATCATTGGCCTTTCCATCGTGCTCACCCTGCTGCTGG
CCGGCGTCGCGGTGCTGCTGGCGAGCCGCCTGCTGCGTCCCATCGGCCAGTTGGCGGGCGTGATGGAACGCCTCGCGCAG
GACGACCTGTCCGTGGAAATCCCCCACCAGGACAAGAAGAACGAGTTCGGCGTGATGGCCCACACCATTCAGGTGTTCCG
CGACCATGCGGACGAGCGCCGCGTGCTTCAGGCAGAGCAGGAGCGCCAGACCGCCCAGCGCCTCGCCCGGCAGGAGGAGG
TGGACGCCATCATCGCCGCCTTCCGCACCCGCATGAGCCGCATGGTGGACGCGGTGCGTCTCAATACCGGCGAGCTTCTG
GATGTGGCGGGCAGTCTCTCGCAGGTGGCGGCCCGCACTACGGCACGGACGGTGGAAGCCGACCGGGCCTCCCAGGAGGC
CAGCAACTCCGTGCAGGGCGTGGCCGGCGCCACGGAGGAGCTCTCGGCATCCATCGGCGAGATCACCTCCCAGGTGTCAC
GCGCCTCCACCGTCGTCGCCGATGCCACCCGCGGCGCCCAGAGCACGGGCAGCAAGGTGCGGGAACTGTCGGAAGGCGCC
GAGCGGATCGGCAAGGTGGTGGAACTCATCCAGGCCATCGCCGCCCAGACCAACCTCCTGGCCCTCAACGCCACCATCGA
GGCGGCGCGGGCCGGCGAGATGGGCAAGGGTTTCGCCGTGGTGGCGCAGGAGGTGAAGGAACTCGCCGCCCAGACCGGCA
AGGCGACCGAAGAGATCGGCCACCAGATCCAGAGCATCCAGGGCGCGACCGCCGATGTGGTGCAGGCCATCGAGCAGATC
GTCGTCACCATCGGCGATGTGGACCGCTACACCAGCGCCATCGCCTCGGCCGTCACCCAGCAGAATGCCGCCACCGGCGA
GATCACGCGGAACATCGTCGCCGCCTCGCAGGGCAGTGCCACGGTGGCGTCCAACATCACCCATGTGATGCAGGCGGTGA
ATGAGACCGACACTTGCGCCAGCCGGGTGACGGACGCCACGCGCCGGCTCGCCGACGACAACAGCCAGCTCAACGCGGCG
CTGGAGGACTTTCTGGCCCGCGTCGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
CATGTTGCCTCAAGCAAGAATTCGACCGCCCCGCGCAAGCTTTCCAGGCTATACGTAATAATACGTATGCCCTTGGCGTA
CGCCCTCTCCGCCCGAGGAT

Downstream 100 bases:

>100_bases
CGGCCGGCAGTCCCGTTTCAGAAAAGCCCGGGCGTCGCGGCGCCCGGGCTCTTGCGCGGCCTGCTGACCGCCGGGCAAAG
AAAAACCCCGCGCCGTCACC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MPPMPRLNLKVSHAVALMVFSCVAVTAALLIAVVAWMLDDDAAQNAINRQNVAIRAAAIALAKAVPGSRIDWSGNTVSRI
VLPRLPEPGDHGLIDDVSRISGGTATVFAYDAGKDDFVRLSTSVKKADGTRAVGTVLGRQSAAYPAMKAGTIYRGEATIL
DVPYYTVYLPVFDPSGSVIGVVYGGVKQDEVDARLNSLLRTIIGLSIVLTLLLAGVAVLLASRLLRPIGQLAGVMERLAQ
DDLSVEIPHQDKKNEFGVMAHTIQVFRDHADERRVLQAEQERQTAQRLARQEEVDAIIAAFRTRMSRMVDAVRLNTGELL
DVAGSLSQVAARTTARTVEADRASQEASNSVQGVAGATEELSASIGEITSQVSRASTVVADATRGAQSTGSKVRELSEGA
ERIGKVVELIQAIAAQTNLLALNATIEAARAGEMGKGFAVVAQEVKELAAQTGKATEEIGHQIQSIQGATADVVQAIEQI
VVTIGDVDRYTSAIASAVTQQNAATGEITRNIVAASQGSATVASNITHVMQAVNETDTCASRVTDATRRLADDNSQLNAA
LEDFLARVVAA

Sequences:

>Translated_571_residues
MPPMPRLNLKVSHAVALMVFSCVAVTAALLIAVVAWMLDDDAAQNAINRQNVAIRAAAIALAKAVPGSRIDWSGNTVSRI
VLPRLPEPGDHGLIDDVSRISGGTATVFAYDAGKDDFVRLSTSVKKADGTRAVGTVLGRQSAAYPAMKAGTIYRGEATIL
DVPYYTVYLPVFDPSGSVIGVVYGGVKQDEVDARLNSLLRTIIGLSIVLTLLLAGVAVLLASRLLRPIGQLAGVMERLAQ
DDLSVEIPHQDKKNEFGVMAHTIQVFRDHADERRVLQAEQERQTAQRLARQEEVDAIIAAFRTRMSRMVDAVRLNTGELL
DVAGSLSQVAARTTARTVEADRASQEASNSVQGVAGATEELSASIGEITSQVSRASTVVADATRGAQSTGSKVRELSEGA
ERIGKVVELIQAIAAQTNLLALNATIEAARAGEMGKGFAVVAQEVKELAAQTGKATEEIGHQIQSIQGATADVVQAIEQI
VVTIGDVDRYTSAIASAVTQQNAATGEITRNIVAASQGSATVASNITHVMQAVNETDTCASRVTDATRRLADDNSQLNAA
LEDFLARVVAA
>Mature_570_residues
PPMPRLNLKVSHAVALMVFSCVAVTAALLIAVVAWMLDDDAAQNAINRQNVAIRAAAIALAKAVPGSRIDWSGNTVSRIV
LPRLPEPGDHGLIDDVSRISGGTATVFAYDAGKDDFVRLSTSVKKADGTRAVGTVLGRQSAAYPAMKAGTIYRGEATILD
VPYYTVYLPVFDPSGSVIGVVYGGVKQDEVDARLNSLLRTIIGLSIVLTLLLAGVAVLLASRLLRPIGQLAGVMERLAQD
DLSVEIPHQDKKNEFGVMAHTIQVFRDHADERRVLQAEQERQTAQRLARQEEVDAIIAAFRTRMSRMVDAVRLNTGELLD
VAGSLSQVAARTTARTVEADRASQEASNSVQGVAGATEELSASIGEITSQVSRASTVVADATRGAQSTGSKVRELSEGAE
RIGKVVELIQAIAAQTNLLALNATIEAARAGEMGKGFAVVAQEVKELAAQTGKATEEIGHQIQSIQGATADVVQAIEQIV
VTIGDVDRYTSAIASAVTQQNAATGEITRNIVAASQGSATVASNITHVMQAVNETDTCASRVTDATRRLADDNSQLNAAL
EDFLARVVAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=232, Percent_Identity=31.0344827586207, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=252, Percent_Identity=30.5555555555556, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787690, Length=380, Percent_Identity=28.1578947368421, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI2367378, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788195, Length=176, Percent_Identity=34.0909090909091, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60233; Mature: 60102

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMPRLNLKVSHAVALMVFSCVAVTAALLIAVVAWMLDDDAAQNAINRQNVAIRAAAIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LAKAVPGSRIDWSGNTVSRIVLPRLPEPGDHGLIDDVSRISGGTATVFAYDAGKDDFVRL
HHHCCCCCCCCCCCCCHHHEECCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEH
STSVKKADGTRAVGTVLGRQSAAYPAMKAGTIYRGEATILDVPYYTVYLPVFDPSGSVIG
HHHHHHCCCCHHHHHHHHCCHHCCCCHHCCEEEECCEEEEECCEEEEEEEEECCCCCEEE
VVYGGVKQDEVDARLNSLLRTIIGLSIVLTLLLAGVAVLLASRLLRPIGQLAGVMERLAQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDLSVEIPHQDKKNEFGVMAHTIQVFRDHADERRVLQAEQERQTAQRLARQEEVDAIIAA
CCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRTRMSRMVDAVRLNTGELLDVAGSLSQVAARTTARTVEADRASQEASNSVQGVAGATEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LSASIGEITSQVSRASTVVADATRGAQSTGSKVRELSEGAERIGKVVELIQAIAAQTNLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ALNATIEAARAGEMGKGFAVVAQEVKELAAQTGKATEEIGHQIQSIQGATADVVQAIEQI
EEECHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VVTIGDVDRYTSAIASAVTQQNAATGEITRNIVAASQGSATVASNITHVMQAVNETDTCA
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
SRVTDATRRLADDNSQLNAALEDFLARVVAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPMPRLNLKVSHAVALMVFSCVAVTAALLIAVVAWMLDDDAAQNAINRQNVAIRAAAIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LAKAVPGSRIDWSGNTVSRIVLPRLPEPGDHGLIDDVSRISGGTATVFAYDAGKDDFVRL
HHHCCCCCCCCCCCCCHHHEECCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEH
STSVKKADGTRAVGTVLGRQSAAYPAMKAGTIYRGEATILDVPYYTVYLPVFDPSGSVIG
HHHHHHCCCCHHHHHHHHCCHHCCCCHHCCEEEECCEEEEECCEEEEEEEEECCCCCEEE
VVYGGVKQDEVDARLNSLLRTIIGLSIVLTLLLAGVAVLLASRLLRPIGQLAGVMERLAQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDLSVEIPHQDKKNEFGVMAHTIQVFRDHADERRVLQAEQERQTAQRLARQEEVDAIIAA
CCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRTRMSRMVDAVRLNTGELLDVAGSLSQVAARTTARTVEADRASQEASNSVQGVAGATEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LSASIGEITSQVSRASTVVADATRGAQSTGSKVRELSEGAERIGKVVELIQAIAAQTNLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ALNATIEAARAGEMGKGFAVVAQEVKELAAQTGKATEEIGHQIQSIQGATADVVQAIEQI
EEECHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VVTIGDVDRYTSAIASAVTQQNAATGEITRNIVAASQGSATVASNITHVMQAVNETDTCA
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
SRVTDATRRLADDNSQLNAALEDFLARVVAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]