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The map label for this gene is 158421682

Identifier: 158421682

GI number: 158421682

Start: 72227

End: 72811

Strand: Reverse

Name: 158421682

Synonym: AZC_0058

Alternate gene names: NA

Gene position: 72811-72227 (Counterclockwise)

Preceding gene: 158421683

Following gene: 158421681

Centisome position: 1.36

GC content: 67.18

Gene sequence:

>585_bases
ATGGTCAAGCTGAACAAGATCTACACGCGGACCGGAGACGATGGCTCGACCGGACTCGGCACGGGCGAGCGCGTGCGGAA
GGATGATCTGCGTGTCGCCGCCTACGGCACGGTGGATGAGACCAATGCCACGATCGGTCTCGTGCGGCTGCACCTCGCAG
CCTATCCGCAGGTCGACGCCATTCTGGCCCGCGTCCAGAACGACCTGTTCGATCTCGGCGCGGACCTCTGCGTCCCCGAG
CGGCCCGGCGCGCCGCCCCCGCCCTACGAGCCGCTGCGAATCACCGCGCCGCAGGTCCGGCGGCTGGAGGAGGACATCGA
CCGACTGAATGCGGAACTCGATCCCCTGAAATCTTTCATCCTCCCTGGCGGCACCCCGGCCGCCGCCCACCTGCACCTCG
CGCGCACCGTCGCGCGGCGGGCGGAGCGGGACATGGTGACGCTCGCGGAAAGCGACGGCGAGCAGGTGGGCATGGAGGCA
CTCAGATACATCAATCGTTTATCCGACCTGCTTTTTGTCGCCGGGCGCTACGTCAATGGCCACGGAGCCAACGACGTGCT
CTGGGTTCCCGGCGCTCATAGGTGA

Upstream 100 bases:

>100_bases
GAAATTGATGCAGCTGCGCGTGCTCTTTCAGTTCGGTGCGGTGGTGCTGGTGATGATCACCATCTATGCCATGCGCCACT
GACTTCGGTTCGGGGACAAG

Downstream 100 bases:

>100_bases
AGATCAAGGCGGCTCAGGGCTCCGGACACGGTGCCGGAACGGGTGCATCCGTTAGCCTGCGATGTATCTAAAGCCGCCGC
CGAGGCTTTACAGCGCCCGA

Product: cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MVKLNKIYTRTGDDGSTGLGTGERVRKDDLRVAAYGTVDETNATIGLVRLHLAAYPQVDAILARVQNDLFDLGADLCVPE
RPGAPPPPYEPLRITAPQVRRLEEDIDRLNAELDPLKSFILPGGTPAAAHLHLARTVARRAERDMVTLAESDGEQVGMEA
LRYINRLSDLLFVAGRYVNGHGANDVLWVPGAHR

Sequences:

>Translated_194_residues
MVKLNKIYTRTGDDGSTGLGTGERVRKDDLRVAAYGTVDETNATIGLVRLHLAAYPQVDAILARVQNDLFDLGADLCVPE
RPGAPPPPYEPLRITAPQVRRLEEDIDRLNAELDPLKSFILPGGTPAAAHLHLARTVARRAERDMVTLAESDGEQVGMEA
LRYINRLSDLLFVAGRYVNGHGANDVLWVPGAHR
>Mature_194_residues
MVKLNKIYTRTGDDGSTGLGTGERVRKDDLRVAAYGTVDETNATIGLVRLHLAAYPQVDAILARVQNDLFDLGADLCVPE
RPGAPPPPYEPLRITAPQVRRLEEDIDRLNAELDPLKSFILPGGTPAAAHLHLARTVARRAERDMVTLAESDGEQVGMEA
LRYINRLSDLLFVAGRYVNGHGANDVLWVPGAHR

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=176, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115534154, Length=180, Percent_Identity=33.8888888888889, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21211; Mature: 21211

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLNKIYTRTGDDGSTGLGTGERVRKDDLRVAAYGTVDETNATIGLVRLHLAAYPQVDA
CCCCCCEEEECCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHH
ILARVQNDLFDLGADLCVPERPGAPPPPYEPLRITAPQVRRLEEDIDRLNAELDPLKSFI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCHHHHHHHH
LPGGTPAAAHLHLARTVARRAERDMVTLAESDGEQVGMEALRYINRLSDLLFVAGRYVNG
CCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGANDVLWVPGAHR
CCCCCEEECCCCCC
>Mature Secondary Structure
MVKLNKIYTRTGDDGSTGLGTGERVRKDDLRVAAYGTVDETNATIGLVRLHLAAYPQVDA
CCCCCCEEEECCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHH
ILARVQNDLFDLGADLCVPERPGAPPPPYEPLRITAPQVRRLEEDIDRLNAELDPLKSFI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCHHHHHHHH
LPGGTPAAAHLHLARTVARRAERDMVTLAESDGEQVGMEALRYINRLSDLLFVAGRYVNG
CCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGANDVLWVPGAHR
CCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]