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The map label for this gene is infC

Identifier: 15836521

GI number: 15836521

Start: 1136289

End: 1136849

Strand: Direct

Name: infC

Synonym: CPj0990

Alternate gene names: 15836521

Gene position: 1136289-1136849 (Clockwise)

Preceding gene: 15836518

Following gene: 15836522

Centisome position: 92.64

GC content: 37.97

Gene sequence:

>561_bases
GTGGCATTAAATTTTAAGATTAACAGGCAAATAAGAGCTCCTAAAGTTCGTCTCATTGGTTCAGCCGGAGAACAGTTAGG
AATACTTGCTATCAAAGATGCTTTGGATTTAGCCCGAGAGGCAGGTCTTGATTTAGTTGAAGTTGCTTCAAATAGCGAGC
CTCCTGTATGTAAGATCATGGACTACGGTAAATACCGTTATGGTCTGACAAAAAAGGAAAAAGATAGTAAAAAAGCTCAA
CATCAGGTGCGCATAAAAGAAGTTAAGCTTAAGCCTAACATAGACGAAAATGATTTTTCGACTAAGTTAAAGCAAGCGCG
TACGTTCGTTGAAAAAGGAAATAAAGTCAAAATTACATGCATGTTCCGTGGTAGAGAATTAGCTTATCCAGAACATGGTT
TTAAAGTTGTTCAAAAAATGAGTCAGGGTTTAGAGGATATTGGTTTCGTTGAAGCTGAACCCAAACTAGCAGGTCGTTCC
TTGATTTGTGTTGTGGCTCCAGGAACAGTAAAAACAAAGAAAAAACAGGAAAAGTCTCATGCCCAAGATGAAAACCAATA
A

Upstream 100 bases:

>100_bases
TCTTCTTGTCTAGAACGGATAAAAGATCGGATTGTCTTTTCTGGAACACTCAGTGCTTTCAGACCATAGCAATTGTCTTA
ACAGGAAATTGAGATAGAGT

Downstream 100 bases:

>100_bases
GTCTGTTTCAGCACGTTTTAAATTAACAGCCTCAGGCCAATTAAAAAGAACTCGTCCAGGGAAGAGACATAAGTTGTCTA
AAAAGTCTTCGCAAGAAAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MALNFKINRQIRAPKVRLIGSAGEQLGILAIKDALDLAREAGLDLVEVASNSEPPVCKIMDYGKYRYGLTKKEKDSKKAQ
HQVRIKEVKLKPNIDENDFSTKLKQARTFVEKGNKVKITCMFRGRELAYPEHGFKVVQKMSQGLEDIGFVEAEPKLAGRS
LICVVAPGTVKTKKKQEKSHAQDENQ

Sequences:

>Translated_186_residues
MALNFKINRQIRAPKVRLIGSAGEQLGILAIKDALDLAREAGLDLVEVASNSEPPVCKIMDYGKYRYGLTKKEKDSKKAQ
HQVRIKEVKLKPNIDENDFSTKLKQARTFVEKGNKVKITCMFRGRELAYPEHGFKVVQKMSQGLEDIGFVEAEPKLAGRS
LICVVAPGTVKTKKKQEKSHAQDENQ
>Mature_185_residues
ALNFKINRQIRAPKVRLIGSAGEQLGILAIKDALDLAREAGLDLVEVASNSEPPVCKIMDYGKYRYGLTKKEKDSKKAQH
QVRIKEVKLKPNIDENDFSTKLKQARTFVEKGNKVKITCMFRGRELAYPEHGFKVVQKMSQGLEDIGFVEAEPKLAGRSL
ICVVAPGTVKTKKKQEKSHAQDENQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=47.6744186046512, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CHLPN (Q9Z6R9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86614
- PIR:   G72010
- RefSeq:   NP_225184.1
- RefSeq:   NP_301045.1
- RefSeq:   NP_445403.1
- RefSeq:   NP_877300.1
- ProteinModelPortal:   Q9Z6R9
- SMR:   Q9Z6R9
- GeneID:   1467707
- GeneID:   895598
- GeneID:   919758
- GeneID:   963314
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0865
- KEGG:   cpn:CPn0990
- KEGG:   cpt:CpB1028
- TIGR:   CP_0865
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- PhylomeDB:   Q9Z6R9
- ProtClustDB:   PRK00028
- BioCyc:   CPNE115711:CP_0865-MONOMER
- BioCyc:   CPNE115713:CPN0990-MONOMER
- BioCyc:   CPNE138677:CPJ0990-MONOMER
- BioCyc:   CPNE182082:CPB1028-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20868; Mature: 20736

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNFKINRQIRAPKVRLIGSAGEQLGILAIKDALDLAREAGLDLVEVASNSEPPVCKIM
CEEEEEECCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
DYGKYRYGLTKKEKDSKKAQHQVRIKEVKLKPNIDENDFSTKLKQARTFVEKGNKVKITC
ECCCEECCCCCCCHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGFKVVQKMSQGLEDIGFVEAEPKLAGRSLICVVAPGTVKTKKKQEKSH
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHC
AQDENQ
CCCCCC
>Mature Secondary Structure 
ALNFKINRQIRAPKVRLIGSAGEQLGILAIKDALDLAREAGLDLVEVASNSEPPVCKIM
EEEEEECCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
DYGKYRYGLTKKEKDSKKAQHQVRIKEVKLKPNIDENDFSTKLKQARTFVEKGNKVKITC
ECCCEECCCCCCCHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGFKVVQKMSQGLEDIGFVEAEPKLAGRSLICVVAPGTVKTKKKQEKSH
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHC
AQDENQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362