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The map label for this gene is aas

Identifier: 15836455

GI number: 15836455

Start: 1051662

End: 1053278

Strand: Direct

Name: aas

Synonym: CPj0922

Alternate gene names: 15836455

Gene position: 1051662-1053278 (Clockwise)

Preceding gene: 15836454

Following gene: 15836456

Centisome position: 85.74

GC content: 41.31

Gene sequence:

>1617_bases
ATGCACGATCAACGGAATAGGGGTCATAACAACCATAATTTAAGGTTGCGACCTGGATCTACATTATTGGAAGCTTTTTT
AATATTATGTTCCGAACATGAAGAGGGAATTGCCTGTTTTGACGAACATCTAGGCTCACTCTCTTATCGAGAACTTCGCA
ATGCTATAATTGCTGTAGCAATTAAGGTCTCCAAGTTTTCTGAAGATAGAGTTGGGGTGATGATGCCCGCATCTATAGGA
GCATTCATTGCCTATTTTGGCATTCTTCTTGCGGGGAAGACTCCCGTAATGATGAACTGGAGTCAAGGACTCAGAGAGCT
ACGTGCATGTACAAAAACAGTAGAGGTTCGACGTGTTCTTACTTCACAGCAGTTCATCAAACATTTAACTGAGGTCCAAG
GGTTCGTAGAATATCCCTTTGATCTTATGTATATGGAAGATGTGCGTAAACGCCTTTCCTGGTGGGAGAAGTGCCGGATA
GGGTTGTATTCTAAATGCTCCGTCCCTTGGTTGCTCAGAATCTTTGGAGTTTCAGGGGTTGAGAGCGATGATACTGCTGT
CATTTTGTTTACTTCTGGAACAGAAAAACTTCCAAAAGCAGTCCCTCTAACCCATAAGAATTTAATGGAAAATCAGGAGG
CATGCCTCAAATTTTTCGATCCTAATACACAAGATGTCATGTTGGCATTTCTCCCTCCTTTTCATGCTTATGGATTCAAT
AGCTGTGGCTTGTTTCCTTTACTGATGGGCGTTCATGTAGTATTCGCTTCGAATCCTCTAAACCCTAAAAAGTTAGTTGA
GTTTATCGATGATAAAAAGGTCACCTTCTTTGGGAGCACTCCGGTATTTTTCGACTATATTCTGAAAACAGCAAAAAAAC
AAAATTCCTGTTTGGAGTCCCTACGACTTGTTGTGATCGGCGGGGATGCATTGAAAGATACCCTCTACGAAGAAACTAAG
AAATTACAACCACAAATTGCTCTCTATCAGGGCTACGGTGCTACCGAATGTTCTCCTGTAATTTCGATTACTACGAAAGA
AAGTCCTAGGAAATCCGAGTGTGTGGGAATGCCGATCGAAGGGATGGATGTGCTGATTATTTCTAAAGAGACTCATATTC
CCGTATCCTCGGGAGAACAGGGATTGATCGTTGTTCGTGGGAACTCTGTATTTTCAGGATATCTTGGGAACCATGAACAT
CAGAGTTTTGTCTCCTTAGGTGGGGATCAGTGGTATTTGACTGGAGATTTGGGTCATATAGGTCCTAGCGGGGATCTATT
TTTAGAAGGTAGGCTAAGCCGATTTGTAAAAATCGGTGGAGAAATGGTAAGCCTAGAAGCTTTAGAAAGTATTTTGCATG
AGCATTTTACTGAAAATCAAAATGAAGACGCAGGTTCCCTAGTGGTGTGTGGTATTCCTGGGGATAAGGTAAGGCTGTGT
TTATTTACTACTCTTGCTACAACAATACATGAAGTAAATGATATCTTAAAAAGCGCTGAAACCAGTAGCATAGTGAAGAT
ATCGTATGTGCATCAGGTTGAAAGCATTCCTATCTTAGGCATTGGGAAACCTGATTACGTTTCATTAAATGCGCTGGCTG
TTTCATTATTTGGGTAA

Upstream 100 bases:

>100_bases
CAAAACAAGACCTAAATACTTTTTTGGCTTCTTGGTTTAATCAAGGAGATGACAATTTGCCCATAGAAGTTCCTTACGCA
TAACGAGGAAGTTACGACGT

Downstream 100 bases:

>100_bases
GTAGCCGTTTCTCTGGGTAGGTTGATACATAGTGAGTTTGCAAGGAGAGTTTCTTGACTACCAGTGATGTTATAGATTTT
GTAACAAATGATTTTCTAGG

Product: long chain fatty acid--[acyl-carrier-protein] ligase

Products: NA

Alternate protein names: 2-acylglycerophosphoethanolamine acyltransferase; 2-acyl-GPE acyltransferase; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase; Acyl-[acyl-carrier-protein] synthetase; Acyl-ACP synthetase; Long-chain-fatty-acid--[acyl-carrier-protein] ligase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MHDQRNRGHNNHNLRLRPGSTLLEAFLILCSEHEEGIACFDEHLGSLSYRELRNAIIAVAIKVSKFSEDRVGVMMPASIG
AFIAYFGILLAGKTPVMMNWSQGLRELRACTKTVEVRRVLTSQQFIKHLTEVQGFVEYPFDLMYMEDVRKRLSWWEKCRI
GLYSKCSVPWLLRIFGVSGVESDDTAVILFTSGTEKLPKAVPLTHKNLMENQEACLKFFDPNTQDVMLAFLPPFHAYGFN
SCGLFPLLMGVHVVFASNPLNPKKLVEFIDDKKVTFFGSTPVFFDYILKTAKKQNSCLESLRLVVIGGDALKDTLYEETK
KLQPQIALYQGYGATECSPVISITTKESPRKSECVGMPIEGMDVLIISKETHIPVSSGEQGLIVVRGNSVFSGYLGNHEH
QSFVSLGGDQWYLTGDLGHIGPSGDLFLEGRLSRFVKIGGEMVSLEALESILHEHFTENQNEDAGSLVVCGIPGDKVRLC
LFTTLATTIHEVNDILKSAETSSIVKISYVHQVESIPILGIGKPDYVSLNALAVSLFG

Sequences:

>Translated_538_residues
MHDQRNRGHNNHNLRLRPGSTLLEAFLILCSEHEEGIACFDEHLGSLSYRELRNAIIAVAIKVSKFSEDRVGVMMPASIG
AFIAYFGILLAGKTPVMMNWSQGLRELRACTKTVEVRRVLTSQQFIKHLTEVQGFVEYPFDLMYMEDVRKRLSWWEKCRI
GLYSKCSVPWLLRIFGVSGVESDDTAVILFTSGTEKLPKAVPLTHKNLMENQEACLKFFDPNTQDVMLAFLPPFHAYGFN
SCGLFPLLMGVHVVFASNPLNPKKLVEFIDDKKVTFFGSTPVFFDYILKTAKKQNSCLESLRLVVIGGDALKDTLYEETK
KLQPQIALYQGYGATECSPVISITTKESPRKSECVGMPIEGMDVLIISKETHIPVSSGEQGLIVVRGNSVFSGYLGNHEH
QSFVSLGGDQWYLTGDLGHIGPSGDLFLEGRLSRFVKIGGEMVSLEALESILHEHFTENQNEDAGSLVVCGIPGDKVRLC
LFTTLATTIHEVNDILKSAETSSIVKISYVHQVESIPILGIGKPDYVSLNALAVSLFG
>Mature_538_residues
MHDQRNRGHNNHNLRLRPGSTLLEAFLILCSEHEEGIACFDEHLGSLSYRELRNAIIAVAIKVSKFSEDRVGVMMPASIG
AFIAYFGILLAGKTPVMMNWSQGLRELRACTKTVEVRRVLTSQQFIKHLTEVQGFVEYPFDLMYMEDVRKRLSWWEKCRI
GLYSKCSVPWLLRIFGVSGVESDDTAVILFTSGTEKLPKAVPLTHKNLMENQEACLKFFDPNTQDVMLAFLPPFHAYGFN
SCGLFPLLMGVHVVFASNPLNPKKLVEFIDDKKVTFFGSTPVFFDYILKTAKKQNSCLESLRLVVIGGDALKDTLYEETK
KLQPQIALYQGYGATECSPVISITTKESPRKSECVGMPIEGMDVLIISKETHIPVSSGEQGLIVVRGNSVFSGYLGNHEH
QSFVSLGGDQWYLTGDLGHIGPSGDLFLEGRLSRFVKIGGEMVSLEALESILHEHFTENQNEDAGSLVVCGIPGDKVRLC
LFTTLATTIHEVNDILKSAETSSIVKISYVHQVESIPILGIGKPDYVSLNALAVSLFG

Specific function: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=278, Percent_Identity=27.6978417266187, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI187761345, Length=468, Percent_Identity=23.5042735042735, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI187761343, Length=468, Percent_Identity=23.5042735042735, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1789201, Length=553, Percent_Identity=28.5714285714286, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI145693145, Length=277, Percent_Identity=30.6859205776173, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788107, Length=441, Percent_Identity=24.2630385487528, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786810, Length=419, Percent_Identity=22.673031026253, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994694, Length=433, Percent_Identity=24.4803695150115, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71994703, Length=433, Percent_Identity=24.4803695150115, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71994690, Length=433, Percent_Identity=24.4803695150115, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559526, Length=361, Percent_Identity=27.1468144044321, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17558820, Length=279, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560308, Length=308, Percent_Identity=26.6233766233766, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=276, Percent_Identity=26.8115942028986, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531443, Length=350, Percent_Identity=23.1428571428571, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538037, Length=392, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17557194, Length=374, Percent_Identity=25.9358288770053, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985884, Length=286, Percent_Identity=26.2237762237762, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560140, Length=339, Percent_Identity=24.4837758112094, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507435, Length=267, Percent_Identity=23.9700374531835, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319699, Length=487, Percent_Identity=23.2032854209446, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859661, Length=287, Percent_Identity=27.1777003484321, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581924, Length=410, Percent_Identity=24.8780487804878, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648260, Length=277, Percent_Identity=29.6028880866426, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355181, Length=416, Percent_Identity=21.3942307692308, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922652, Length=283, Percent_Identity=23.321554770318, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130357, Length=276, Percent_Identity=24.2753623188406, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356441, Length=275, Percent_Identity=22.1818181818182, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648253, Length=279, Percent_Identity=25.089605734767, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF01553 Acyltransferase; PF00501 AMP-binding [H]

EC number: =2.3.1.40; =6.2.1.20 [H]

Molecular weight: Translated: 59737; Mature: 59737

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDQRNRGHNNHNLRLRPGSTLLEAFLILCSEHEEGIACFDEHLGSLSYRELRNAIIAVA
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHEEEE
IKVSKFSEDRVGVMMPASIGAFIAYFGILLAGKTPVMMNWSQGLRELRACTKTVEVRRVL
EEEECCCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
TSQQFIKHLTEVQGFVEYPFDLMYMEDVRKRLSWWEKCRIGLYSKCSVPWLLRIFGVSGV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
ESDDTAVILFTSGTEKLPKAVPLTHKNLMENQEACLKFFDPNTQDVMLAFLPPFHAYGFN
CCCCCEEEEEECCCCCCCCCCCCCHHHHHCCHHHHHEECCCCCCCEEEEECCCHHHCCCC
SCGLFPLLMGVHVVFASNPLNPKKLVEFIDDKKVTFFGSTPVFFDYILKTAKKQNSCLES
CCCHHHHHHHHEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LRLVVIGGDALKDTLYEETKKLQPQIALYQGYGATECSPVISITTKESPRKSECVGMPIE
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCC
GMDVLIISKETHIPVSSGEQGLIVVRGNSVFSGYLGNHEHQSFVSLGGDQWYLTGDLGHI
CCEEEEEECCCCCCCCCCCCEEEEEECCCEEECCCCCCCCHHHHHCCCCEEEEECCCCCC
GPSGDLFLEGRLSRFVKIGGEMVSLEALESILHEHFTENQNEDAGSLVVCGIPGDKVRLC
CCCCCEEEHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEHH
LFTTLATTIHEVNDILKSAETSSIVKISYVHQVESIPILGIGKPDYVSLNALAVSLFG
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCEEECCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MHDQRNRGHNNHNLRLRPGSTLLEAFLILCSEHEEGIACFDEHLGSLSYRELRNAIIAVA
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHEEEE
IKVSKFSEDRVGVMMPASIGAFIAYFGILLAGKTPVMMNWSQGLRELRACTKTVEVRRVL
EEEECCCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
TSQQFIKHLTEVQGFVEYPFDLMYMEDVRKRLSWWEKCRIGLYSKCSVPWLLRIFGVSGV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
ESDDTAVILFTSGTEKLPKAVPLTHKNLMENQEACLKFFDPNTQDVMLAFLPPFHAYGFN
CCCCCEEEEEECCCCCCCCCCCCCHHHHHCCHHHHHEECCCCCCCEEEEECCCHHHCCCC
SCGLFPLLMGVHVVFASNPLNPKKLVEFIDDKKVTFFGSTPVFFDYILKTAKKQNSCLES
CCCHHHHHHHHEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LRLVVIGGDALKDTLYEETKKLQPQIALYQGYGATECSPVISITTKESPRKSECVGMPIE
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCC
GMDVLIISKETHIPVSSGEQGLIVVRGNSVFSGYLGNHEHQSFVSLGGDQWYLTGDLGHI
CCEEEEEECCCCCCCCCCCCEEEEEECCCEEECCCCCCCCHHHHHCCCCEEEEECCCCCC
GPSGDLFLEGRLSRFVKIGGEMVSLEALESILHEHFTENQNEDAGSLVVCGIPGDKVRLC
CCCCCEEEHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEHH
LFTTLATTIHEVNDILKSAETSSIVKISYVHQVESIPILGIGKPDYVSLNALAVSLFG
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCEEECCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA