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The map label for this gene is recD_2

Identifier: 15836285

GI number: 15836285

Start: 847925

End: 849406

Strand: Direct

Name: recD_2

Synonym: CPj0752

Alternate gene names: 15836285

Gene position: 847925-849406 (Clockwise)

Preceding gene: 15836284

Following gene: 15836288

Centisome position: 69.13

GC content: 39.74

Gene sequence:

>1482_bases
TTGCACACAGAATTTGCTCCTTTTTTAGAAGACTTAGTACATCAGCAGGTGATATCCCCTTTAGACATCGCTTTTGCTTC
TAAGCACATCTCTTCGGACTTTGAAGAGTCTTTTGTTTTTCTCGCGGTCTCCTCAGCGCTTTGGCGTTATGGTCATCCTT
TTCTTTCCCTTGAGGAAAATCGCATTAGACCTTCTCTAGGAGGGATCTCAGAAACAGATTTGTATCGGGGATTTCATAAC
CTTCCTAAGGAAGTTCGAGATAAATTATTTGTCGTTGTTTCAGGACGTTTGTATTTACGGTCTCTGTATACGATACGATC
GAAACTCTTAGACAAGCTTTCGTTGCTTTGTTCAGCAACCCCGAATTATTTTCCTCCTTCTATAGATTCTTCGATCCTTT
CAGAAGAGCAAAACTTTATTTTTAATAAAATAACTCAAGGATGTTTTTCTATAGTTTCTGGAGGCCCAGGAACAGGAAAA
ACTTTTTTAGCTGCACAACTCATCCTCTCTTTAGTGAAGCAGCAACCTAAGTTACGTATTGCTATAGTATCTCCTACAGG
AAAGGCCACGTCTCATATTCGTCAGATTCTTATGAAATATAATATATTTGACGACATGGTGTTGATGCAGACGGTGCACC
ACTTTCTTCAGGAGTATGCGTACCGTCGCTATAACTCTATAGATGTCCTTTTAGTAGATGAAGGCTCTATGGTAACTTTT
GACTTGTTGTATAGTTTGGTACAAACCCTACAGGGATATGAGAAAGACAAAAAACTTTATACCTCGAGTTTAATTATTCT
CGGAGATACCAATCAATTGCCTCCTATTGGCATTGGGGTTGGAAATCCCCTTCAAGATCTCATAGGATATTTCCATGAAA
ATACGTTTTTCCTGAAGACATCGCATAGGGCAAAGACTGGAGTTGTGGATCAGCTGACTCAATCTGTATTGCGTGGCGAA
ATGATTTCTTTTTCTCCTCTCCCATCGATATCCTCAGCTATAGAAGTCTTGAAAAATCGTTTTGTAAAGTCGTTACGTCA
ATCAGAAGCACGTTTGTGTGTATTGACTCCTATGCGCCATGGCCCTTGGGGGGTTCTGAACTTAAACACAATGATACATC
AAAGATTGGCGAGAAGCGATCCTGATTTACGTATTCCTATTATGGTGACGAGTCGTTATGAAACTTGGGGACTATTTAAT
GGAGACACAGGATTACTGTGTTTAAAAACTCAGAAATTGCATTTCCCTCAACATGAACCCATAGATTCTAGGGCTCTATC
ACAATACGTCTACAATTACGTTATGTCTGTACACAAGAGCCAGGGGAGTGAATACGATGAGGTTATTGTAATTATTCCCA
AGGGAAGCGAAGTGTTTGGGGTGTCTATTCTCTATACTGCAATTACCCGAGCTAAATATAGAGTTTCAGTTTGGGGAGAT
CCCGAGACGTTACATAAGATAATTAAGAAGTCTAATTACTAG

Upstream 100 bases:

>100_bases
GCTTAGGAACTATTCTCCGAGTGTTTAGGAAAAGATTTTCGAATCTTCATGCATTCATGTTATGTTAGACTCTATAACGG
AATCAAAGTAGGGATGGGCA

Downstream 100 bases:

>100_bases
ATTCTTATCAAAATAAAAAAACCCTCAAAGAATACTCTAAGAGGGTTTTTTTGCTGCGAATGTCGTTAAAAACTATCCTA
TTTTAGCATAATCTTTAACA

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MHTEFAPFLEDLVHQQVISPLDIAFASKHISSDFEESFVFLAVSSALWRYGHPFLSLEENRIRPSLGGISETDLYRGFHN
LPKEVRDKLFVVVSGRLYLRSLYTIRSKLLDKLSLLCSATPNYFPPSIDSSILSEEQNFIFNKITQGCFSIVSGGPGTGK
TFLAAQLILSLVKQQPKLRIAIVSPTGKATSHIRQILMKYNIFDDMVLMQTVHHFLQEYAYRRYNSIDVLLVDEGSMVTF
DLLYSLVQTLQGYEKDKKLYTSSLIILGDTNQLPPIGIGVGNPLQDLIGYFHENTFFLKTSHRAKTGVVDQLTQSVLRGE
MISFSPLPSISSAIEVLKNRFVKSLRQSEARLCVLTPMRHGPWGVLNLNTMIHQRLARSDPDLRIPIMVTSRYETWGLFN
GDTGLLCLKTQKLHFPQHEPIDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKGSEVFGVSILYTAITRAKYRVSVWGD
PETLHKIIKKSNY

Sequences:

>Translated_493_residues
MHTEFAPFLEDLVHQQVISPLDIAFASKHISSDFEESFVFLAVSSALWRYGHPFLSLEENRIRPSLGGISETDLYRGFHN
LPKEVRDKLFVVVSGRLYLRSLYTIRSKLLDKLSLLCSATPNYFPPSIDSSILSEEQNFIFNKITQGCFSIVSGGPGTGK
TFLAAQLILSLVKQQPKLRIAIVSPTGKATSHIRQILMKYNIFDDMVLMQTVHHFLQEYAYRRYNSIDVLLVDEGSMVTF
DLLYSLVQTLQGYEKDKKLYTSSLIILGDTNQLPPIGIGVGNPLQDLIGYFHENTFFLKTSHRAKTGVVDQLTQSVLRGE
MISFSPLPSISSAIEVLKNRFVKSLRQSEARLCVLTPMRHGPWGVLNLNTMIHQRLARSDPDLRIPIMVTSRYETWGLFN
GDTGLLCLKTQKLHFPQHEPIDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKGSEVFGVSILYTAITRAKYRVSVWGD
PETLHKIIKKSNY
>Mature_493_residues
MHTEFAPFLEDLVHQQVISPLDIAFASKHISSDFEESFVFLAVSSALWRYGHPFLSLEENRIRPSLGGISETDLYRGFHN
LPKEVRDKLFVVVSGRLYLRSLYTIRSKLLDKLSLLCSATPNYFPPSIDSSILSEEQNFIFNKITQGCFSIVSGGPGTGK
TFLAAQLILSLVKQQPKLRIAIVSPTGKATSHIRQILMKYNIFDDMVLMQTVHHFLQEYAYRRYNSIDVLLVDEGSMVTF
DLLYSLVQTLQGYEKDKKLYTSSLIILGDTNQLPPIGIGVGNPLQDLIGYFHENTFFLKTSHRAKTGVVDQLTQSVLRGE
MISFSPLPSISSAIEVLKNRFVKSLRQSEARLCVLTPMRHGPWGVLNLNTMIHQRLARSDPDLRIPIMVTSRYETWGLFN
GDTGLLCLKTQKLHFPQHEPIDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKGSEVFGVSILYTAITRAKYRVSVWGD
PETLHKIIKKSNY

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=438, Percent_Identity=26.027397260274, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 55879; Mature: 55879

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTEFAPFLEDLVHQQVISPLDIAFASKHISSDFEESFVFLAVSSALWRYGHPFLSLEEN
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
RIRPSLGGISETDLYRGFHNLPKEVRDKLFVVVSGRLYLRSLYTIRSKLLDKLSLLCSAT
CCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCC
PNYFPPSIDSSILSEEQNFIFNKITQGCFSIVSGGPGTGKTFLAAQLILSLVKQQPKLRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
AIVSPTGKATSHIRQILMKYNIFDDMVLMQTVHHFLQEYAYRRYNSIDVLLVDEGSMVTF
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHH
DLLYSLVQTLQGYEKDKKLYTSSLIILGDTNQLPPIGIGVGNPLQDLIGYFHENTFFLKT
HHHHHHHHHHHCCHHHHHHEECEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
SHRAKTGVVDQLTQSVLRGEMISFSPLPSISSAIEVLKNRFVKSLRQSEARLCVLTPMRH
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GPWGVLNLNTMIHQRLARSDPDLRIPIMVTSRYETWGLFNGDTGLLCLKTQKLHFPQHEP
CCCCEEEHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCC
IDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKGSEVFGVSILYTAITRAKYRVSVWGD
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEEECCC
PETLHKIIKKSNY
HHHHHHHHHCCCC
>Mature Secondary Structure
MHTEFAPFLEDLVHQQVISPLDIAFASKHISSDFEESFVFLAVSSALWRYGHPFLSLEEN
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
RIRPSLGGISETDLYRGFHNLPKEVRDKLFVVVSGRLYLRSLYTIRSKLLDKLSLLCSAT
CCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCC
PNYFPPSIDSSILSEEQNFIFNKITQGCFSIVSGGPGTGKTFLAAQLILSLVKQQPKLRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
AIVSPTGKATSHIRQILMKYNIFDDMVLMQTVHHFLQEYAYRRYNSIDVLLVDEGSMVTF
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHH
DLLYSLVQTLQGYEKDKKLYTSSLIILGDTNQLPPIGIGVGNPLQDLIGYFHENTFFLKT
HHHHHHHHHHHCCHHHHHHEECEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
SHRAKTGVVDQLTQSVLRGEMISFSPLPSISSAIEVLKNRFVKSLRQSEARLCVLTPMRH
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GPWGVLNLNTMIHQRLARSDPDLRIPIMVTSRYETWGLFNGDTGLLCLKTQKLHFPQHEP
CCCCEEEHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCC
IDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKGSEVFGVSILYTAITRAKYRVSVWGD
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEEECCC
PETLHKIIKKSNY
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]