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The map label for this gene is ribC

Identifier: 15836063

GI number: 15836063

Start: 613392

End: 613994

Strand: Reverse

Name: ribC

Synonym: CPj0532

Alternate gene names: 15836063

Gene position: 613994-613392 (Counterclockwise)

Preceding gene: 15836075

Following gene: 15836062

Centisome position: 50.06

GC content: 38.31

Gene sequence:

>603_bases
ATGTTTTCAGGAATTATTCAAGAATTAGGTGAAGTGTGTTTTTTTGAAGCTCAAGGAAATGGTCTGAGTTTAGGAATTAA
GAGCACGCCACTATTTGTCACCCCTCTGGTTACAGGGGATAGCGTAGCCGTAGATGGAGTCTGTTTGACTTTAACATCAT
GCAATGAAAGTAAGATCTTTTTTGATGTGATTCCAGAAACTCTAGCTTGTACGACTTTGGGAGAAAAAAGATGTAGCGAT
CAAGTGAACTTAGAGGCTGCATTAAAAATGGGAGACTCGATTGGAGGTCACTTACTCTCTGGGCATGTTTTTGGAACAGC
AGAGATTTTCTTGATAAAAGAAAATCGTTATTATTTCCGTGGTTCCAAAGAATTATCTCAGTACCTTTTTGAAAAAGGGT
TTATTGCAATTGATGGTATCAGCTTAACGCTAGTGTCAGTTGATAGTGATACGTTTTCTGTGGGATTGATTCCTGAGACT
CTTCAAAGGACGACTTTAGGAAAGAAAAGGGAAGGAGAAAGAGTCAATATCGAGATCGATATGTCAACAAAGATACAGGT
AGACACAGTAAAACGTATTTTAGCCTCATCAGGGAAAGATTAG

Upstream 100 bases:

>100_bases
AAATTTCTGTGCAAAATTGCTTTGCTTATTGAGACGAAAAAAACATACTCTACTCTAGGAAAGCTTTTGTTGTAAAGATT
CTGTTGTTAAATGGGGTGGG

Downstream 100 bases:

>100_bases
TTATGGATTATAAATTGCTCGATAGTGGGGACGGGAACAAATTAGAGTGTTTTGGTCCTGTCACTTTAATTCGTCCTTCA
AGTATTGCTGTTTGGCCAAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIFFDVIPETLACTTLGEKRCSD
QVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFRGSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPET
LQRTTLGKKREGERVNIEIDMSTKIQVDTVKRILASSGKD

Sequences:

>Translated_200_residues
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIFFDVIPETLACTTLGEKRCSD
QVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFRGSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPET
LQRTTLGKKREGERVNIEIDMSTKIQVDTVKRILASSGKD
>Mature_200_residues
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIFFDVIPETLACTTLGEKRCSD
QVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFRGSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPET
LQRTTLGKKREGERVNIEIDMSTKIQVDTVKRILASSGKD

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats

Homologues:

Organism=Escherichia coli, GI1787952, Length=201, Percent_Identity=46.2686567164179, Blast_Score=164, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=33.1730769230769, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISA_CHLPN (Q9Z820)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   E72066
- PIR:   H86556
- RefSeq:   NP_224728.1
- RefSeq:   NP_300587.1
- RefSeq:   NP_444771.1
- RefSeq:   NP_876825.1
- ProteinModelPortal:   Q9Z820
- SMR:   Q9Z820
- GeneID:   1467232
- GeneID:   895387
- GeneID:   919295
- GeneID:   963827
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0220
- KEGG:   cpn:CPn0532
- KEGG:   cpt:CpB0553
- TIGR:   CP_0220
- HOGENOM:   HBG289809
- OMA:   CCLTVTK
- PhylomeDB:   Q9Z820
- ProtClustDB:   PRK09289
- BioCyc:   CPNE115711:CP_0220-MONOMER
- BioCyc:   CPNE115713:CPN0532-MONOMER
- BioCyc:   CPNE138677:CPJ0532-MONOMER
- BioCyc:   CPNE182082:CPB0553-MONOMER
- BRENDA:   2.5.1.9
- InterPro:   IPR001783
- InterPro:   IPR017938
- PANTHER:   PTHR21098
- PIRSF:   PIRSF000498
- TIGRFAMs:   TIGR00187

Pfam domain/function: PF00677 Lum_binding; SSF63380 Riboflavin_synthase_like_b-brl

EC number: =2.5.1.9

Molecular weight: Translated: 21701; Mature: 21701

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS51177 LUMAZINE_BIND

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIF
CCHHHHHHHHHEEEEEECCCEEEEEECCCCEEEEEEECCCCEEECCEEEEEECCCCCEEE
FDVIPETLACTTLGEKRCSDQVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFR
EEECCCHHHHHCCCHHHCCCCCCHHEEECCCCCCCCEEEECEEEEEEEEEEEECCEEEEE
GSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPETLQRTTLGKKREGERVNIEID
CCHHHHHHHHHCCCEEEECCEEEEEEECCCCEEEECCHHHHHHHHCCCCCCCCEEEEEEE
MSTKIQVDTVKRILASSGKD
CCCEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIF
CCHHHHHHHHHEEEEEECCCEEEEEECCCCEEEEEEECCCCEEECCEEEEEECCCCCEEE
FDVIPETLACTTLGEKRCSDQVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFR
EEECCCHHHHHCCCHHHCCCCCCHHEEECCCCCCCCEEEECEEEEEEEEEEEECCEEEEE
GSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPETLQRTTLGKKREGERVNIEID
CCHHHHHHHHHCCCEEEECCEEEEEEECCCCEEEECCHHHHHHHHCCCCCCCCEEEEEEE
MSTKIQVDTVKRILASSGKD
CCCEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362