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The map label for this gene is gltT

Identifier: 15836059

GI number: 15836059

Start: 609238

End: 610482

Strand: Reverse

Name: gltT

Synonym: CPj0528

Alternate gene names: 15836059

Gene position: 610482-609238 (Counterclockwise)

Preceding gene: 15836060

Following gene: 15836058

Centisome position: 49.77

GC content: 42.17

Gene sequence:

>1245_bases
ATGAAATTATGGATGAAGATCTTTATTGGATTGTTTGTCGGGGTTACCTTAGGTTTAGTTTTAGAAGATAAAGCCATCTT
TTTTAAACCTATAGGAGACATCTTTTTAAATCTATTGAGCATGGTAGTGTATCCTTTAGTGTTCTGCTCAATGGTTTTAG
GAATCGCTTCCATTAGCGATATGAAAAAATTGGGACGCATTGGCATTAAAAGTGTCGGCCTCTATCTAGGGACTACGGCA
CTAGCTATTGTGATTGGCTTGTGTTTTGCTTGGATTTTCTCTCCAGGAAATGGGTGTGATTTTGCCCAGGCCCAATCTAT
GGATTCGGCCGTTACTGTCATTGATTCAAACAAAACAGCGGCGTATTTTCTTTCTATAATAGCTCAAGTTTTCCCATCGA
ATCCTGTACGCTCTTTTGCTGAAGGGAATATATTACAAATTATTATTTTTGCGATTTTCTTAGGAATTGCCCTTCGGCTT
TCTGGAGAACGTGGCCGCCCTGTCGAGCGTTTTATTGATGGTTTTTCTGAAATCATGTTGCGCATGGTAAATATGATCAT
GAGTTTTGCTCCCTATGGTGTGGGAGCTAGCATGGCATGGATTTCGGGAAATCATGGTTTAGGAGTCCTTTGGCAGCTAG
GCAAATTTATCATTGCTTACTATCTGGCGTGTTTGTTCCATGCTACGCTTGTTTTTGGGGGACTTGTGCGTTTTGGTTGC
AAGATGTCCTTTTCGAAGTTTCTCTCTTCAATGATGGATGCGATTTCTTGCGCGGTATCTACAGCGAGTAGTTCTGCGAC
TTTACCTGTAACGATGCGTTGTGTTTCTAAAAATTTGGGAGTGTCCGCTGAGGTTTCTGGTTTTGTTTTGCCTCTAGGCG
CCACTGTGAATATGAATGGAACTGCAATTTTTCAGGGTATGGCAGCGGTTTTCATTGCTCAAGCATACAATTGTCCGCTA
TCCTTGAGCAGTCTGTTATTATTGGTAGTTACCGCAACATTCTCTGCCGTGGGTAGTGCCGGTGTTCCTGGAGGAGGTAT
GATTACTCTGGGTTCCGTATTAGCCTCTGTAGGTTTACCTATCCAGGGTATCGCTATACTTGCTGGGATTGACCGGTTAA
GGGATATTGTAGGTACACCCATGAATATTCTTGGGGATGCTGTAGTTGCTACTTATGTAGCTTCTGGAGAAGGAGAGCTT
TCTCCTTATGAATCAATAAAACAGGAAAGCGTTGAAACTACATAG

Upstream 100 bases:

>100_bases
TGCCGATAGCTAAGGTGGAAATGCGCCTTTCTGTGAATCAAGACGATACACTTTCTCTTCTCAACATGATTGAACAAATA
CATAAAAACAGGGGTAACTA

Downstream 100 bases:

>100_bases
AAGGTAACGATACATGATATTTGAGTTCCGATTCCCTAAAATAGGAGAGACGAGTTCCGGAGGATCTATAGTCCGTTGGT
TAAAAAATTTGGGTGATCAT

Product: glutamate symport

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKLWMKIFIGLFVGVTLGLVLEDKAIFFKPIGDIFLNLLSMVVYPLVFCSMVLGIASISDMKKLGRIGIKSVGLYLGTTA
LAIVIGLCFAWIFSPGNGCDFAQAQSMDSAVTVIDSNKTAAYFLSIIAQVFPSNPVRSFAEGNILQIIIFAIFLGIALRL
SGERGRPVERFIDGFSEIMLRMVNMIMSFAPYGVGASMAWISGNHGLGVLWQLGKFIIAYYLACLFHATLVFGGLVRFGC
KMSFSKFLSSMMDAISCAVSTASSSATLPVTMRCVSKNLGVSAEVSGFVLPLGATVNMNGTAIFQGMAAVFIAQAYNCPL
SLSSLLLLVVTATFSAVGSAGVPGGGMITLGSVLASVGLPIQGIAILAGIDRLRDIVGTPMNILGDAVVATYVASGEGEL
SPYESIKQESVETT

Sequences:

>Translated_414_residues
MKLWMKIFIGLFVGVTLGLVLEDKAIFFKPIGDIFLNLLSMVVYPLVFCSMVLGIASISDMKKLGRIGIKSVGLYLGTTA
LAIVIGLCFAWIFSPGNGCDFAQAQSMDSAVTVIDSNKTAAYFLSIIAQVFPSNPVRSFAEGNILQIIIFAIFLGIALRL
SGERGRPVERFIDGFSEIMLRMVNMIMSFAPYGVGASMAWISGNHGLGVLWQLGKFIIAYYLACLFHATLVFGGLVRFGC
KMSFSKFLSSMMDAISCAVSTASSSATLPVTMRCVSKNLGVSAEVSGFVLPLGATVNMNGTAIFQGMAAVFIAQAYNCPL
SLSSLLLLVVTATFSAVGSAGVPGGGMITLGSVLASVGLPIQGIAILAGIDRLRDIVGTPMNILGDAVVATYVASGEGEL
SPYESIKQESVETT
>Mature_414_residues
MKLWMKIFIGLFVGVTLGLVLEDKAIFFKPIGDIFLNLLSMVVYPLVFCSMVLGIASISDMKKLGRIGIKSVGLYLGTTA
LAIVIGLCFAWIFSPGNGCDFAQAQSMDSAVTVIDSNKTAAYFLSIIAQVFPSNPVRSFAEGNILQIIIFAIFLGIALRL
SGERGRPVERFIDGFSEIMLRMVNMIMSFAPYGVGASMAWISGNHGLGVLWQLGKFIIAYYLACLFHATLVFGGLVRFGC
KMSFSKFLSSMMDAISCAVSTASSSATLPVTMRCVSKNLGVSAEVSGFVLPLGATVNMNGTAIFQGMAAVFIAQAYNCPL
SLSSLLLLVVTATFSAVGSAGVPGGGMITLGSVLASVGLPIQGIAILAGIDRLRDIVGTPMNILGDAVVATYVASGEGEL
SPYESIKQESVETT

Specific function: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=426, Percent_Identity=33.5680751173709, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI5032093, Length=407, Percent_Identity=35.1351351351351, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI169790839, Length=466, Percent_Identity=30.0429184549356, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI223468566, Length=286, Percent_Identity=38.4615384615385, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI223468564, Length=277, Percent_Identity=38.2671480144404, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI40254478, Length=441, Percent_Identity=29.7052154195011, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI194239697, Length=447, Percent_Identity=28.1879194630872, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4827012, Length=279, Percent_Identity=35.84229390681, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI66773030, Length=432, Percent_Identity=26.8518518518519, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI262359914, Length=377, Percent_Identity=28.6472148541114, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI301601644, Length=143, Percent_Identity=44.7552447552448, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1790514, Length=389, Percent_Identity=33.9331619537275, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789947, Length=400, Percent_Identity=33.75, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788024, Length=385, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789473, Length=217, Percent_Identity=29.4930875576037, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71996953, Length=432, Percent_Identity=28.7037037037037, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI193206505, Length=440, Percent_Identity=30.6818181818182, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17537407, Length=394, Percent_Identity=30.4568527918782, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI71983099, Length=416, Percent_Identity=29.0865384615385, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71983106, Length=416, Percent_Identity=29.0865384615385, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193206654, Length=399, Percent_Identity=28.3208020050125, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17541374, Length=417, Percent_Identity=28.537170263789, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24583025, Length=452, Percent_Identity=25.8849557522124, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI17137668, Length=452, Percent_Identity=25.8849557522124, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24583023, Length=452, Percent_Identity=25.8849557522124, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281360481, Length=452, Percent_Identity=27.212389380531, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281360483, Length=452, Percent_Identity=27.212389380531, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17137666, Length=452, Percent_Identity=27.212389380531, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43679; Mature: 43679

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWMKIFIGLFVGVTLGLVLEDKAIFFKPIGDIFLNLLSMVVYPLVFCSMVLGIASISD
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKKLGRIGIKSVGLYLGTTALAIVIGLCFAWIFSPGNGCDFAQAQSMDSAVTVIDSNKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCHH
AYFLSIIAQVFPSNPVRSFAEGNILQIIIFAIFLGIALRLSGERGRPVERFIDGFSEIML
HHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RMVNMIMSFAPYGVGASMAWISGNHGLGVLWQLGKFIIAYYLACLFHATLVFGGLVRFGC
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMSFSKFLSSMMDAISCAVSTASSSATLPVTMRCVSKNLGVSAEVSGFVLPLGATVNMNG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCCEEEECCCEECCCC
TAIFQGMAAVFIAQAYNCPLSLSSLLLLVVTATFSAVGSAGVPGGGMITLGSVLASVGLP
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
IQGIAILAGIDRLRDIVGTPMNILGDAVVATYVASGEGELSPYESIKQESVETT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKLWMKIFIGLFVGVTLGLVLEDKAIFFKPIGDIFLNLLSMVVYPLVFCSMVLGIASISD
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKKLGRIGIKSVGLYLGTTALAIVIGLCFAWIFSPGNGCDFAQAQSMDSAVTVIDSNKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCHH
AYFLSIIAQVFPSNPVRSFAEGNILQIIIFAIFLGIALRLSGERGRPVERFIDGFSEIML
HHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RMVNMIMSFAPYGVGASMAWISGNHGLGVLWQLGKFIIAYYLACLFHATLVFGGLVRFGC
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMSFSKFLSSMMDAISCAVSTASSSATLPVTMRCVSKNLGVSAEVSGFVLPLGATVNMNG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCCEEEECCCEECCCC
TAIFQGMAAVFIAQAYNCPLSLSSLLLLVVTATFSAVGSAGVPGGGMITLGSVLASVGLP
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
IQGIAILAGIDRLRDIVGTPMNILGDAVVATYVASGEGELSPYESIKQESVETT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA