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Identifier: 15836036

GI number: 15836036

Start: 587839

End: 588429

Strand: Direct

Name: Not Available

Synonym: CPj0505

Alternate gene names: NA

Gene position: 587839-588429 (Clockwise)

Preceding gene: 15836035

Following gene: 15836037

Centisome position: 47.93

GC content: 46.02

Gene sequence:

>591_bases
GTGCTACAAGAACATTTTTTTCTATCGGAAGATGTAATTACACTAGCGCAACAGCTTTTAGGACATAAACTCATCACAAC
ACATGAGGGTCTGATAACTTCAGGTTACATTGTAGAAACCGAAGCGTATCGTGGCCCTGATGACAAAGCATGCCACGCCT
ACAACTACAGAAAAACTCAGAGGAACAGAGCGATGTACCTGAAAGGAGGCTCTGCTTACCTCTACCGTTGCTATGGCATG
CATCACCTATTGAATGTTGTCACTGGACCTGAGGACATTCCCCATGCCGTCCTGATCCGGGCCATCCTTCCTGATCAAGG
CAAAGAACTTATGATCCAACGCCGCCAATGGAGAGATAAACCCCCACACCTTCTCACCAATGGACCCGGAAAAGTGTGCC
AAGCTCTAGGAATCTCTTTGGAAAACAATAGGCAACGCCTAAATACCCCAGCTCTCTATATCAGCAAAGAAAAAATCTCT
GGGACTCTAACAGCAACTGCCCGGATCGGCATCGATTATGCTCAAGAGTATCGTGATGTCCCATGGAGATTTCTCCTATC
CCCAGAAGATTCGGGAAAAGTTTTATCTTAA

Upstream 100 bases:

>100_bases
AAAATCGTCTGGTCTATAGCGACAACCACAGAAGATAAACCTAAGAAAATAAAGAAAACGCCTTCTAAGAAAAAAGGAAC
GAAAAAAAGAGCCTCGTAAC

Downstream 100 bases:

>100_bases
ATAATCTTAAGCTGTATAGTAAAGAAACAAATGCCCATTTCCTCATATCTTGCAGGAGAATCATGAAAAAATACTTTATT
ACAGGACTTGTTATTCTCCT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLQEHFFLSEDVITLAQQLLGHKLITTHEGLITSGYIVETEAYRGPDDKACHAYNYRKTQRNRAMYLKGGSAYLYRCYGM
HHLLNVVTGPEDIPHAVLIRAILPDQGKELMIQRRQWRDKPPHLLTNGPGKVCQALGISLENNRQRLNTPALYISKEKIS
GTLTATARIGIDYAQEYRDVPWRFLLSPEDSGKVLS

Sequences:

>Translated_196_residues
MLQEHFFLSEDVITLAQQLLGHKLITTHEGLITSGYIVETEAYRGPDDKACHAYNYRKTQRNRAMYLKGGSAYLYRCYGM
HHLLNVVTGPEDIPHAVLIRAILPDQGKELMIQRRQWRDKPPHLLTNGPGKVCQALGISLENNRQRLNTPALYISKEKIS
GTLTATARIGIDYAQEYRDVPWRFLLSPEDSGKVLS
>Mature_196_residues
MLQEHFFLSEDVITLAQQLLGHKLITTHEGLITSGYIVETEAYRGPDDKACHAYNYRKTQRNRAMYLKGGSAYLYRCYGM
HHLLNVVTGPEDIPHAVLIRAILPDQGKELMIQRRQWRDKPPHLLTNGPGKVCQALGISLENNRQRLNTPALYISKEKIS
GTLTATARIGIDYAQEYRDVPWRFLLSPEDSGKVLS

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=141, Percent_Identity=38.2978723404255, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI62632765, Length=141, Percent_Identity=38.2978723404255, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI62632771, Length=141, Percent_Identity=38.2978723404255, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_CHLPN (Q9Z847)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C72071
- PIR:   E86553
- RefSeq:   NP_224701.1
- RefSeq:   NP_300560.1
- RefSeq:   NP_444799.1
- RefSeq:   NP_876798.1
- ProteinModelPortal:   Q9Z847
- SMR:   Q9Z847
- GeneID:   1467205
- GeneID:   895324
- GeneID:   919250
- GeneID:   962914
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0248
- KEGG:   cpj:CPj0505
- KEGG:   cpn:CPn0505
- KEGG:   cpt:CpB0526
- TIGR:   CP_0248
- HOGENOM:   HBG664239
- OMA:   ACHAYRR
- ProtClustDB:   CLSK510663
- BioCyc:   CPNE115711:CP_0248-MONOMER
- BioCyc:   CPNE115713:CPN0505-MONOMER
- BioCyc:   CPNE138677:CPJ0505-MONOMER
- BioCyc:   CPNE182082:CPB0526-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 22291; Mature: 22291

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEHFFLSEDVITLAQQLLGHKLITTHEGLITSGYIVETEAYRGPDDKACHAYNYRKTQ
CCCCHHCCHHHHHHHHHHHHCCCCEECCCCEEECCEEEEECCCCCCCCCCEECCCCHHHC
RNRAMYLKGGSAYLYRCYGMHHLLNVVTGPEDIPHAVLIRAILPDQGKELMIQRRQWRDK
CCCEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
PPHLLTNGPGKVCQALGISLENNRQRLNTPALYISKEKISGTLTATARIGIDYAQEYRDV
CCCEEECCHHHHHHHHCCCCCCCCHHCCCCEEEEEHHHCCEEEEEEEEECCHHHHHHHCC
PWRFLLSPEDSGKVLS
CEEEEECCCCCCCCCC
>Mature Secondary Structure
MLQEHFFLSEDVITLAQQLLGHKLITTHEGLITSGYIVETEAYRGPDDKACHAYNYRKTQ
CCCCHHCCHHHHHHHHHHHHCCCCEECCCCEEECCEEEEECCCCCCCCCCEECCCCHHHC
RNRAMYLKGGSAYLYRCYGMHHLLNVVTGPEDIPHAVLIRAILPDQGKELMIQRRQWRDK
CCCEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
PPHLLTNGPGKVCQALGISLENNRQRLNTPALYISKEKISGTLTATARIGIDYAQEYRDV
CCCEEECCHHHHHHHHCCCCCCCCHHCCCCEEEEEHHHCCEEEEEEEEECCHHHHHHHCC
PWRFLLSPEDSGKVLS
CEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362