Click here to switch to the map view.

The map label for this gene is dcd

Identifier: 15835925

GI number: 15835925

Start: 439523

End: 440095

Strand: Direct

Name: dcd

Synonym: CPj0392

Alternate gene names: 15835925

Gene position: 439523-440095 (Clockwise)

Preceding gene: 15835921

Following gene: 15835926

Centisome position: 35.83

GC content: 40.66

Gene sequence:

>573_bases
ATGAGCATAAAAGAAGATAAGTGGATACGAGAGATGGCCCTAAATGCCGATATGATCCATCCCTTTGTTAATGGCCAAGT
GAACGTAAATGAGGAGACAGGCGAAAAACTTATAAGTTACGGCCTATCGAGTTATGGTTACGACCTCCGCCTATCTCGAG
AATTCAAAGTGTTCACCAATGTCTATAACTCTGTTGTTGATCCAAAATGCTTTACTGAGGATATCTTCATCTCTATTACT
GATGACGTCTGTATTGTTCCTCCAAATTCTTTTGCTCTAGCTCGTAGCGTTGAGTATTTCCGAATTCCTAGAAATGTCTT
AACAATGTGTATAGGAAAGTCTACATATGCACGCTGTGGAATTATCGTAAATGTCACACCTTTTGAGCCTGAATGGGAAG
GGCATGTGACTATAGAAATTTCTAACACTACGCCATTGCCAGCGAAAATTTACGCTAATGAAGGGATTGCCCAGGTCTTA
TTCTTTGAGTCTAGTACGACCTGCGAGGTTTCTTATGCAGACAGAAAAGGAAAGTATCAAAAGCAACAAGGCATCACCGT
ACCTTGTGTCTAA

Upstream 100 bases:

>100_bases
CAAAGTCTATCTTATACTTAGAAAAGTTCCCCCCAAAAACCAGTAAATTGAAAAACAGAATATCATTAAGAAAGCAATTT
CAAACTGTTAAGGTTTCTAA

Downstream 100 bases:

>100_bases
AGTTTCAGTAAGAAAAAAAAACTGGGGTTTTAGATTACTAGAAGAAGTGATGATCAAATCCTGGTGGGTGATCTTTAGCA
TCTTAATTGGAGGCTTTGTT

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTNVYNSVVDPKCFTEDIFISIT
DDVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCGIIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVL
FFESSTTCEVSYADRKGKYQKQQGITVPCV

Sequences:

>Translated_190_residues
MSIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTNVYNSVVDPKCFTEDIFISIT
DDVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCGIIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVL
FFESSTTCEVSYADRKGKYQKQQGITVPCV
>Mature_189_residues
SIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTNVYNSVVDPKCFTEDIFISITD
DVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCGIIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVLF
FESSTTCEVSYADRKGKYQKQQGITVPCV

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_CHLPN (Q9Z8F1)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   F72084
- PIR:   F86539
- RefSeq:   NP_224592.1
- RefSeq:   NP_300449.1
- RefSeq:   NP_444911.1
- RefSeq:   NP_876678.1
- ProteinModelPortal:   Q9Z8F1
- SMR:   Q9Z8F1
- GeneID:   1467085
- GeneID:   894877
- GeneID:   919239
- GeneID:   963059
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0363
- KEGG:   cpn:CPn0392
- KEGG:   cpt:CpB0404
- TIGR:   CP_0363
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q9Z8F1
- ProtClustDB:   PRK00416
- BioCyc:   CPNE115711:CP_0363-MONOMER
- BioCyc:   CPNE115713:CPN0392-MONOMER
- BioCyc:   CPNE138677:CPJ0392-MONOMER
- BioCyc:   CPNE182082:CPB0404-MONOMER
- BRENDA:   3.5.4.13
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 21475; Mature: 21344

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTN
CCCCHHHHHHHHHCCCHHCCCCCCCEEEECHHHHHHHHHHHHHHCCEEEEECCHHHHHHH
VYNSVVDPKCFTEDIFISITDDVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCG
HHHHHCCCCCCCCEEEEEEECCEEEECCCCCCHHHCHHHEECCHHHHHHHHCCCCHHHCE
IIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVLFFESSTTCEVSYADRKGKYQ
EEEEECCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCH
KQQGITVPCV
HHCCEECCCC
>Mature Secondary Structure 
SIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTN
CCCHHHHHHHHHCCCHHCCCCCCCEEEECHHHHHHHHHHHHHHCCEEEEECCHHHHHHH
VYNSVVDPKCFTEDIFISITDDVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCG
HHHHHCCCCCCCCEEEEEEECCEEEECCCCCCHHHCHHHEECCHHHHHHHHCCCCHHHCE
IIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVLFFESSTTCEVSYADRKGKYQ
EEEEECCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCH
KQQGITVPCV
HHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362