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The map label for this gene is flhA

Identifier: 15835896

GI number: 15835896

Start: 407649

End: 409397

Strand: Reverse

Name: flhA

Synonym: CPj0363

Alternate gene names: 15835896

Gene position: 409397-407649 (Counterclockwise)

Preceding gene: 15835910

Following gene: 15835895

Centisome position: 33.38

GC content: 41.05

Gene sequence:

>1749_bases
GTGTCTGGGAAGAAAGATGGTGTAAGGGGAATGATCTTTGTCCCTCTTAGCATCCTAGTACTAATCTTTTTACCTCTTCC
TCAGATCCTTCTTGATTTTGGATTGTGTATTAGTTTTGCATTGTCTTTACTAACGGTCTGTTGGGTCTTTACCTTAAATT
CAAGCAATTCAGCGAAGCTTTTTCCTCCATTTTTCTTATATCTTTGCCTATTGCGGTTGGGATTGAATCTTGCATCAACA
CGATGGATTGTCTCTTCAGGAACCGCCTCTTCTCTGATTGTTTCTTTAGGCAGTTTCTTCTCTTTAGGAAGTCTATGGGC
AGCAACGTTTGCGTGCCTCCTTCTTTTCTTTGTGAACTTTTTGATGGTTTCAAAGGGTTCGGAAAGAATCGCAGAGGTCC
GTTCGCGGTTTTTCTTAGAGGCTCTTCCAGCAAAACAGATGGCTTTAGATTCTGATCTTGTTTCTGGAAGAGCTTCTTAT
AAGGCTGTCAAAAAACAAAAAAATGCCCTTATAGAAGAAGGGGATTTCTTCTCTGCCATGGAGGGGGTCTTTCGTTTTGT
TAAAGGGGATGCAATTATTAGTTGTATCCTTTTACTCGTGAACGTAGTTTCTGTAACTTGTCTTTATTATACTTCGGGTT
ATGCTCTTGAGCAGATGTGGTTTACAGTTTTAGGAGATGCTTTAGTGAGTCAAGTACCTGCTTTACTTACTTCGTGTGCT
GCAGCCACTCTTATTAGTAAAATCGATAAGGAAGAGAGCCTTTTAAATTACCTGTTCGAATACTACAAACAGTTGCGTCA
GCATTTCAGGGTGGTGTCGTTATTGATCTTTTCTTTGTGCTGCATTCCCAGTTCTCCAAAATTCCCTATCGTTTTGCTCG
CGAGTCTTTTATGGTTGGCGTATCGAAAAGAAGAGCCTGCATCAGAAGATTCTTGTATAGAACGTGCGTTCTCTTATGTT
GAGGGGGCCTGCCCTAAGGAACAAGAATCACAGTTCTATCAAGTATATCGTGCAGCATCCGAAGAAGTATTTGAAGATTT
AGGAGTTAGATTGCCTGTGCTTACTTCTCTACGTATTGAAGAGCGTCCTTGGCTCCGAGTATTTGGCCAGAATGTATACT
TAGATGAAATGACTCCAGAGGCTGTGCTTCCTTTCCTTAGAAACATCGCTCATGAGGCTCTCAATGCCGAGGTAGTTCAA
AAGTACCTTGAGGAATCAGAGAGAGTGTTTGGCATCGCTGTTGAAGACATCGTTCCTAAGAAAATCTCTTTAAGCTCTCT
TGTAGTTCTTTCTCGCCTCCTTGTTAGAGAAAGGGTATCGCTTAAGCTTTTCCCAAAGATTCTAGAGGCCGTTGCGGTAT
ACCAAAATTCTGGAGACAGCTTGGAGATCCTTGCGGAAAAAGTGCGAAAGTCTCTCGGATATTGGATTGGGAGAAGTCTC
TGGGATCAGAAACAAACCCTTGAGGTAATTACCATAGATTTTCATGTTGAAGAATTGATAAACAGCTCATACTCAAAGTC
TAATCCTGTAATGCAAGAGAATGTGATCCGTCGAGTAGACAGTCTTTTAGAACGGTCGGTATTTAAAGATTTTCGAGCCA
TAGTTACGAGCTGTGAAACACGATTTGAGATGAAAAAAATGCTCGACCCACATTTCCCTGATCTTTTGGTTTTATCTCAT
GATGAGCTTCCTAAAGAAATCCCTATTTCCTTCTTAGGGATCGTTTCAGATGAGGTTTTAGTTCCTTAA

Upstream 100 bases:

>100_bases
GATCAAAGATGCTTCATAACGTCTCTTTAGAGTTTTACTTGCAGATATATGGAAGAGGGAAGTATGAGAAAAGGCAGGGA
TTCTCTAGGAGGCTGTTTTT

Downstream 100 bases:

>100_bases
TTTAATTTAATCTTCTGTAAGCACTATTACTTTCGTATTTTTTTTGTTGGTGTAAATATTGTTTAAAAATTTTTTTTGAA
TTAATCTAATAAATAACTAG

Product: type III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MSGKKDGVRGMIFVPLSILVLIFLPLPQILLDFGLCISFALSLLTVCWVFTLNSSNSAKLFPPFFLYLCLLRLGLNLAST
RWIVSSGTASSLIVSLGSFFSLGSLWAATFACLLLFFVNFLMVSKGSERIAEVRSRFFLEALPAKQMALDSDLVSGRASY
KAVKKQKNALIEEGDFFSAMEGVFRFVKGDAIISCILLLVNVVSVTCLYYTSGYALEQMWFTVLGDALVSQVPALLTSCA
AATLISKIDKEESLLNYLFEYYKQLRQHFRVVSLLIFSLCCIPSSPKFPIVLLASLLWLAYRKEEPASEDSCIERAFSYV
EGACPKEQESQFYQVYRAASEEVFEDLGVRLPVLTSLRIEERPWLRVFGQNVYLDEMTPEAVLPFLRNIAHEALNAEVVQ
KYLEESERVFGIAVEDIVPKKISLSSLVVLSRLLVRERVSLKLFPKILEAVAVYQNSGDSLEILAEKVRKSLGYWIGRSL
WDQKQTLEVITIDFHVEELINSSYSKSNPVMQENVIRRVDSLLERSVFKDFRAIVTSCETRFEMKKMLDPHFPDLLVLSH
DELPKEIPISFLGIVSDEVLVP

Sequences:

>Translated_582_residues
MSGKKDGVRGMIFVPLSILVLIFLPLPQILLDFGLCISFALSLLTVCWVFTLNSSNSAKLFPPFFLYLCLLRLGLNLAST
RWIVSSGTASSLIVSLGSFFSLGSLWAATFACLLLFFVNFLMVSKGSERIAEVRSRFFLEALPAKQMALDSDLVSGRASY
KAVKKQKNALIEEGDFFSAMEGVFRFVKGDAIISCILLLVNVVSVTCLYYTSGYALEQMWFTVLGDALVSQVPALLTSCA
AATLISKIDKEESLLNYLFEYYKQLRQHFRVVSLLIFSLCCIPSSPKFPIVLLASLLWLAYRKEEPASEDSCIERAFSYV
EGACPKEQESQFYQVYRAASEEVFEDLGVRLPVLTSLRIEERPWLRVFGQNVYLDEMTPEAVLPFLRNIAHEALNAEVVQ
KYLEESERVFGIAVEDIVPKKISLSSLVVLSRLLVRERVSLKLFPKILEAVAVYQNSGDSLEILAEKVRKSLGYWIGRSL
WDQKQTLEVITIDFHVEELINSSYSKSNPVMQENVIRRVDSLLERSVFKDFRAIVTSCETRFEMKKMLDPHFPDLLVLSH
DELPKEIPISFLGIVSDEVLVP
>Mature_581_residues
SGKKDGVRGMIFVPLSILVLIFLPLPQILLDFGLCISFALSLLTVCWVFTLNSSNSAKLFPPFFLYLCLLRLGLNLASTR
WIVSSGTASSLIVSLGSFFSLGSLWAATFACLLLFFVNFLMVSKGSERIAEVRSRFFLEALPAKQMALDSDLVSGRASYK
AVKKQKNALIEEGDFFSAMEGVFRFVKGDAIISCILLLVNVVSVTCLYYTSGYALEQMWFTVLGDALVSQVPALLTSCAA
ATLISKIDKEESLLNYLFEYYKQLRQHFRVVSLLIFSLCCIPSSPKFPIVLLASLLWLAYRKEEPASEDSCIERAFSYVE
GACPKEQESQFYQVYRAASEEVFEDLGVRLPVLTSLRIEERPWLRVFGQNVYLDEMTPEAVLPFLRNIAHEALNAEVVQK
YLEESERVFGIAVEDIVPKKISLSSLVVLSRLLVRERVSLKLFPKILEAVAVYQNSGDSLEILAEKVRKSLGYWIGRSLW
DQKQTLEVITIDFHVEELINSSYSKSNPVMQENVIRRVDSLLERSVFKDFRAIVTSCETRFEMKKMLDPHFPDLLVLSHD
ELPKEIPISFLGIVSDEVLVP

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=320, Percent_Identity=31.5625, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 65634; Mature: 65502

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKKDGVRGMIFVPLSILVLIFLPLPQILLDFGLCISFALSLLTVCWVFTLNSSNSAKL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FPPFFLYLCLLRLGLNLASTRWIVSSGTASSLIVSLGSFFSLGSLWAATFACLLLFFVNF
CCHHHHHHHHHHHCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVSKGSERIAEVRSRFFLEALPAKQMALDSDLVSGRASYKAVKKQKNALIEEGDFFSAM
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHH
EGVFRFVKGDAIISCILLLVNVVSVTCLYYTSGYALEQMWFTVLGDALVSQVPALLTSCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATLISKIDKEESLLNYLFEYYKQLRQHFRVVSLLIFSLCCIPSSPKFPIVLLASLLWLA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
YRKEEPASEDSCIERAFSYVEGACPKEQESQFYQVYRAASEEVFEDLGVRLPVLTSLRIE
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
ERPWLRVFGQNVYLDEMTPEAVLPFLRNIAHEALNAEVVQKYLEESERVFGIAVEDIVPK
CCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEHHHHHCCC
KISLSSLVVLSRLLVRERVSLKLFPKILEAVAVYQNSGDSLEILAEKVRKSLGYWIGRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WDQKQTLEVITIDFHVEELINSSYSKSNPVMQENVIRRVDSLLERSVFKDFRAIVTSCET
HCCCCCEEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFEMKKMLDPHFPDLLVLSHDELPKEIPISFLGIVSDEVLVP
HHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGKKDGVRGMIFVPLSILVLIFLPLPQILLDFGLCISFALSLLTVCWVFTLNSSNSAKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FPPFFLYLCLLRLGLNLASTRWIVSSGTASSLIVSLGSFFSLGSLWAATFACLLLFFVNF
CCHHHHHHHHHHHCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVSKGSERIAEVRSRFFLEALPAKQMALDSDLVSGRASYKAVKKQKNALIEEGDFFSAM
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHH
EGVFRFVKGDAIISCILLLVNVVSVTCLYYTSGYALEQMWFTVLGDALVSQVPALLTSCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATLISKIDKEESLLNYLFEYYKQLRQHFRVVSLLIFSLCCIPSSPKFPIVLLASLLWLA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
YRKEEPASEDSCIERAFSYVEGACPKEQESQFYQVYRAASEEVFEDLGVRLPVLTSLRIE
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
ERPWLRVFGQNVYLDEMTPEAVLPFLRNIAHEALNAEVVQKYLEESERVFGIAVEDIVPK
CCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEHHHHHCCC
KISLSSLVVLSRLLVRERVSLKLFPKILEAVAVYQNSGDSLEILAEKVRKSLGYWIGRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WDQKQTLEVITIDFHVEELINSSYSKSNPVMQENVIRRVDSLLERSVFKDFRAIVTSCET
HCCCCCEEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFEMKKMLDPHFPDLLVLSHDELPKEIPISFLGIVSDEVLVP
HHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]