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The map label for this gene is lcrD

Identifier: 15835858

GI number: 15835858

Start: 366953

End: 369085

Strand: Direct

Name: lcrD

Synonym: CPj0323

Alternate gene names: 15835858

Gene position: 366953-369085 (Clockwise)

Preceding gene: 15835857

Following gene: 15835859

Centisome position: 29.92

GC content: 42.8

Gene sequence:

>2133_bases
ATGAATAAGCTACTCAATTTCGTCAGCAGAACACTTGGTGGCGATACCGCCTTAAACATGATCAATAAGTCCAGCGACTT
AATCCTTGCTCTTTGGATGATGGGCGTTGTCTTAATGATCATTATTCCTTTGCCTCCGCCTATCGTTGACTTGATGATCA
CCATCAACTTATCGATCTCTGTATTCTTATTGATGGTGGCTCTTTATATTCCAAGTGCTTTGCAGCTGTCTGTTTTTCCC
TCGTTGCTCCTCATCACTACGATGTTCCGCTTGGGGATTAATATTTCCTCTTCTCGACAGATTCTCCTTAAAGCGTATGC
GGGTCATGTCATTCAGGCCTTCGGAGACTTCGTGGTTGGAGGGAACTATGTGGTCGGGTTCATTATCTTCCTCATTATTA
CAATCATTCAGTTTATCGTAGTAACTAAGGGTGCCGAGCGTGTTGCCGAAGTTGCTGCCCGATTCCGATTGGATGCGATG
CCAGGTAAACAGATGGCGATTGATGCGGACTTACGAGCTGGTATGATTGATGCCACACAAGCTCGTGATAAAAGGGCTCA
AATCCAAAAGGAAAGTGAACTCTACGGAGCCATGGACGGTGCCATGAAGTTCATCAAAGGAGACGTTATCGCTGGTATCG
TTATCTCTTTGATTAACATTGTTGGCGGTTTGACGATTGGGGTGGCTATGCACGGCATGGACCTCGCTCAAGCAGCTCAC
GTCTACACTCTTCTCTCCATTGGAGATGGTTTAGTCTCTCAAATTCCTTCTCTTTTGATTGCGTTGACAGCGGGTATTGT
CACGACTCGTGTATCGAGTGACAAAAATACGAACTTGGGTAAAGAGATTTCTACTCAGCTCGTTAAAGAACCACGAGCAC
TACTCCTTGCAGGTGCTGCAACTTTAGGGGTTGGTTTCTTCAAGGGCTTCCCTCTATGGTCCTTCTCCATTTTAGCATTA
ATTTTCGTTGCCTTAGGGATTCTCCTACTGACTAAGAAATCAGCGGCAGGAAAAAAAGGTGGTGGCTCAGGAGCTTCAAC
AACCGTAGGGGCTGCTGGTGATGGCGCTGCTACTGTTGGGGATAATCCCGATGACTATTCTCTAACTCTTCCCGTAATTC
TAGAACTTGGAAAAGATCTCTCTAAGCTTATCCAACACAAGACAAAATCAGGACAAAGCTTTGTTGATGATATGATTCCT
AAAATGCGGCAAGCTCTCTATCAGGATATCGGAATCCGATACCCTGGCATTCATGTTCGCACAGATTCCCCTTCTTTAGA
AGGATACGATTATATGATTCTGCTTAATGAAGTCCCTTATGTGCGAGGAAAAATTCCTCCGCACCATGTGTTAACCAATG
AGGTGGAGGACAATCTCAGCCGTTATAATCTACCTTTCATTACCTATAAGAATGCTGCGGGTCTTCCTTCAGCTTGGGTT
AGTGAAGATGCAAAAGCTATTCTAGAGAAGGCAGCAATTAAATATTGGACGCCGCTCGAAGTGATCATTCTCCATCTTTC
GTACTTTTTCCATAAAAGCTCTCAAGAGTTTTTGGGAATTCAAGAGGTACGTTCTATGATCGAATTTATGGAACGTTCAT
TCCCGGACTTAGTGAAGGAAGTCACAAGGCTTATTCCATTGCAAAAGCTTACGGAAATCTTTAAGAGATTGGTTCAAGAG
CAAATCTCAATTAAAGACCTACGTACAATCTTAGAATCTCTGAGCGAGTGGGCGCAAACTGAGAAAGATACAGTTTTGCT
TACAGAATATGTACGGTCTTCTTTAAAGCTTTATATCAGCTTCAAGTTCTCTCAAGGACAATCAGCAATTTCTGTTTATC
TCTTAGATCCAGAAATTGAAGAGATGATTCGTGGAGCAATTAAACAGACATCGGCAGGTTCTTACCTTGCTCTAGATCCT
GATTCTGTGAACCTAATTTTAAAATCTATGAGGAATACGATCACGCCAACACCTGCAGGAGGCCAACCACCAGTATTATT
GACAGCAATTGATGTAAGAAGATATGTACGAAAATTAATAGAAACAGAATTCCCTGACATTGCTGTGATTTCTTATCAAG
AAATCCTACCAGAAATCCGCATCCAGCCTTTAGGAAGAATTCAGATTTTCTAA

Upstream 100 bases:

>100_bases
AATCTACTTACGAAGCTATTGGAGAAATTCTACTCTATATCACTTCACTGAATGCGCAAAATCCTAATAATAAAAATACT
AACCAACCTGATCATTTATA

Downstream 100 bases:

>100_bases
TTGATACGTTGTCGCTCATAGGAGGCATATGGCAGCATCAGGAGGCACAGGTGGTTTAGGAGGCACTCAGGGTGTCAACC
TTGCAGCTGTAGAAGCTGCA

Product: low calcium response D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MNKLLNFVSRTLGGDTALNMINKSSDLILALWMMGVVLMIIIPLPPPIVDLMITINLSISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLKAYAGHVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLTIGVAMHGMDLAQAAH
VYTLLSIGDGLVSQIPSLLIALTAGIVTTRVSSDKNTNLGKEISTQLVKEPRALLLAGAATLGVGFFKGFPLWSFSILAL
IFVALGILLLTKKSAAGKKGGGSGASTTVGAAGDGAATVGDNPDDYSLTLPVILELGKDLSKLIQHKTKSGQSFVDDMIP
KMRQALYQDIGIRYPGIHVRTDSPSLEGYDYMILLNEVPYVRGKIPPHHVLTNEVEDNLSRYNLPFITYKNAAGLPSAWV
SEDAKAILEKAAIKYWTPLEVIILHLSYFFHKSSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQE
QISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDP
DSVNLILKSMRNTITPTPAGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEILPEIRIQPLGRIQIF

Sequences:

>Translated_710_residues
MNKLLNFVSRTLGGDTALNMINKSSDLILALWMMGVVLMIIIPLPPPIVDLMITINLSISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLKAYAGHVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLTIGVAMHGMDLAQAAH
VYTLLSIGDGLVSQIPSLLIALTAGIVTTRVSSDKNTNLGKEISTQLVKEPRALLLAGAATLGVGFFKGFPLWSFSILAL
IFVALGILLLTKKSAAGKKGGGSGASTTVGAAGDGAATVGDNPDDYSLTLPVILELGKDLSKLIQHKTKSGQSFVDDMIP
KMRQALYQDIGIRYPGIHVRTDSPSLEGYDYMILLNEVPYVRGKIPPHHVLTNEVEDNLSRYNLPFITYKNAAGLPSAWV
SEDAKAILEKAAIKYWTPLEVIILHLSYFFHKSSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQE
QISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDP
DSVNLILKSMRNTITPTPAGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEILPEIRIQPLGRIQIF
>Mature_710_residues
MNKLLNFVSRTLGGDTALNMINKSSDLILALWMMGVVLMIIIPLPPPIVDLMITINLSISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLKAYAGHVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLTIGVAMHGMDLAQAAH
VYTLLSIGDGLVSQIPSLLIALTAGIVTTRVSSDKNTNLGKEISTQLVKEPRALLLAGAATLGVGFFKGFPLWSFSILAL
IFVALGILLLTKKSAAGKKGGGSGASTTVGAAGDGAATVGDNPDDYSLTLPVILELGKDLSKLIQHKTKSGQSFVDDMIP
KMRQALYQDIGIRYPGIHVRTDSPSLEGYDYMILLNEVPYVRGKIPPHHVLTNEVEDNLSRYNLPFITYKNAAGLPSAWV
SEDAKAILEKAAIKYWTPLEVIILHLSYFFHKSSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQE
QISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDP
DSVNLILKSMRNTITPTPAGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEILPEIRIQPLGRIQIF

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=670, Percent_Identity=35.5223880597015, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 77871; Mature: 77871

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLNFVSRTLGGDTALNMINKSSDLILALWMMGVVLMIIIPLPPPIVDLMITINLSIS
CCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECHHHH
VFLLMVALYIPSALQLSVFPSLLLITTMFRLGINISSSRQILLKAYAGHVIQAFGDFVVG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAMPGKQMAIDADLRAGMIDATQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCHHH
ARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLTIGVAMHGMDLAQAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VYTLLSIGDGLVSQIPSLLIALTAGIVTTRVSSDKNTNLGKEISTQLVKEPRALLLAGAA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TLGVGFFKGFPLWSFSILALIFVALGILLLTKKSAAGKKGGGSGASTTVGAAGDGAATVG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNPDDYSLTLPVILELGKDLSKLIQHKTKSGQSFVDDMIPKMRQALYQDIGIRYPGIHVR
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TDSPSLEGYDYMILLNEVPYVRGKIPPHHVLTNEVEDNLSRYNLPFITYKNAAGLPSAWV
CCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
SEDAKAILEKAAIKYWTPLEVIILHLSYFFHKSSQEFLGIQEVRSMIEFMERSFPDLVKE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCHHHHHH
VTRLIPLQKLTEIFKRLVQEQISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEE
FKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDSVNLILKSMRNTITPTPAG
EEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCC
GQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEILPEIRIQPLGRIQIF
CCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure
MNKLLNFVSRTLGGDTALNMINKSSDLILALWMMGVVLMIIIPLPPPIVDLMITINLSIS
CCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECHHHH
VFLLMVALYIPSALQLSVFPSLLLITTMFRLGINISSSRQILLKAYAGHVIQAFGDFVVG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAMPGKQMAIDADLRAGMIDATQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCHHH
ARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLTIGVAMHGMDLAQAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VYTLLSIGDGLVSQIPSLLIALTAGIVTTRVSSDKNTNLGKEISTQLVKEPRALLLAGAA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TLGVGFFKGFPLWSFSILALIFVALGILLLTKKSAAGKKGGGSGASTTVGAAGDGAATVG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNPDDYSLTLPVILELGKDLSKLIQHKTKSGQSFVDDMIPKMRQALYQDIGIRYPGIHVR
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TDSPSLEGYDYMILLNEVPYVRGKIPPHHVLTNEVEDNLSRYNLPFITYKNAAGLPSAWV
CCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
SEDAKAILEKAAIKYWTPLEVIILHLSYFFHKSSQEFLGIQEVRSMIEFMERSFPDLVKE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCHHHHHH
VTRLIPLQKLTEIFKRLVQEQISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEE
FKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDSVNLILKSMRNTITPTPAG
EEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCC
GQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEILPEIRIQPLGRIQIF
CCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]