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The map label for this gene is devB

Identifier: 15835774

GI number: 15835774

Start: 275689

End: 276297

Strand: Direct

Name: devB

Synonym: CPj0239

Alternate gene names: 15835774

Gene position: 275689-276297 (Clockwise)

Preceding gene: 15835773

Following gene: 15835779

Centisome position: 22.48

GC content: 36.62

Gene sequence:

>609_bases
ATCTATAAAGATATCGTTATCAATAAAGACAAACTTATAGATCCTAGTAAGATTTTTCTATTTTGGGGAGATGAAAGACT
AGCTCCGATAACATCGTCAGAAAGTAATTACGGCCAGGCTATGAGCATTCTCCGTGATTTGAATATTCCTGATGAGCAGA
TCTTTCGAATGGAAACAGAAAATCCCGATGGAGCGAAAAAATACCAAGAACTTATAGAAAATAAAATTCCTGATGCTAGC
TTTGATATGATTATGTTAGGACTAGGAGAAGATGGTCACACCCTTTCTCTTTTTTCCAATACCTCGGCTTTGGAGGAGGA
AAATGACCTTGTGGTCTTTAATTCTGTTCCACATCTAGAAACAGAAAGAATGACCTTAACCTTTCCTTGCGTACATAAAG
GCAAGCATGTTGTTGTTTATGTTCAGGGGGAAAATAAAAAGCCTATCCTTAAAAGTGTCTTCTTTTCTGAAGGTAGAGAA
GAAAAACTCTATCCTATAGAGCGTGTAGGTAGGGACCGCTCACCTCTATTTTGGATTATTTCTCCAGAATCTTATGATAT
AGCAGACTTCGATAATATCTCTTCGATATATAAAATGGACATCCTCTAA

Upstream 100 bases:

>100_bases
AGATCTAGCTAGTAAAGATTGGATAGCTTCTGCGAACCAGGCAATTAAGCAACGGTGAGCATTTTATGGAGCATTATCTG
GAGGCAAAACTCCTTTAGAA

Downstream 100 bases:

>100_bases
AAAAGATAGGCGTTGCGATTTAGCCGTAGATAGTATCGTAAGCCGGCGGTGGAAAAGGAGGAGGAGCACTAGGCATGGTA
GGAGCCGTAGGGTATCCTGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETENPDGAKKYQELIENKIPDAS
FDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLETERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGRE
EKLYPIERVGRDRSPLFWIISPESYDIADFDNISSIYKMDIL

Sequences:

>Translated_202_residues
MYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETENPDGAKKYQELIENKIPDAS
FDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLETERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGRE
EKLYPIERVGRDRSPLFWIISPESYDIADFDNISSIYKMDIL
>Mature_202_residues
MYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETENPDGAKKYQELIENKIPDAS
FDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLETERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGRE
EKLYPIERVGRDRSPLFWIISPESYDIADFDNISSIYKMDIL

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=171, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI6912586, Length=170, Percent_Identity=33.5294117647059, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321687, Length=160, Percent_Identity=35.625, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324362, Length=166, Percent_Identity=32.5301204819277, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641119, Length=145, Percent_Identity=33.7931034482759, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 23245; Mature: 23245

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETE
CCCCEEECCCCCCCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHCCCCHHHEEEEECC
NPDGAKKYQELIENKIPDASFDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLE
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
TERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGREEKLYPIERVGRDRSPLFWII
CCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEE
SPESYDIADFDNISSIYKMDIL
CCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETE
CCCCEEECCCCCCCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHCCCCHHHEEEEECC
NPDGAKKYQELIENKIPDASFDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLE
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
TERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGREEKLYPIERVGRDRSPLFWII
CCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEE
SPESYDIADFDNISSIYKMDIL
CCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]