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The map label for this gene is groES

Identifier: 15835670

GI number: 15835670

Start: 168851

End: 169159

Strand: Reverse

Name: groES

Synonym: CPj0135

Alternate gene names: 15835670

Gene position: 169159-168851 (Counterclockwise)

Preceding gene: 15835671

Following gene: 15835669

Centisome position: 13.79

GC content: 42.07

Gene sequence:

>309_bases
ATGTCTGATCAAGCAACGACCCTCCGAATTAAACCTTTGGGCGATAGAATCTTGGTAAAAAGGGAAGAAGAAGAAGCCAC
TGCTCGTGGAGGAATCATCTTACCCGATACAGCAAAAAAGAAACAAGATCGTGCTGAGGTCCTTGTTTTAGGCACAGGCA
AACGAACTGATGACGGTACTCTACTTCCTTTCGAAGTTCAAGTTGGCGATATCATTTTAATGGATAAGTATGCAGGTCAA
GAAATCACAATCGATGACGAAGAGTATGTCATTCTACAGTCCAGTGAAATCATGGCCGTCCTAAAATAA

Upstream 100 bases:

>100_bases
TTATTGAGTGCTAAAATTATTGCACAAAAAAAAACGCTTTGTTATCGTGATTGCAGAAATAGCAAAGTCTCTTAGAACGT
AAAACATAAGGAGCATATAA

Downstream 100 bases:

>100_bases
AATACTAGTTTGCAGATTATAGAAAGTTAAGGAGAACAACGATGGCAGCGAAAAATATTAAATATAATGAAGAAGCCAGA
AAAAAAATACATAAAGGGGT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSDQATTLRIKPLGDRILVKREEEEATARGGIILPDTAKKKQDRAEVLVLGTGKRTDDGTLLPFEVQVGDIILMDKYAGQ
EITIDDEEYVILQSSEIMAVLK

Sequences:

>Translated_102_residues
MSDQATTLRIKPLGDRILVKREEEEATARGGIILPDTAKKKQDRAEVLVLGTGKRTDDGTLLPFEVQVGDIILMDKYAGQ
EITIDDEEYVILQSSEIMAVLK
>Mature_101_residues
SDQATTLRIKPLGDRILVKREEEEATARGGIILPDTAKKKQDRAEVLVLGTGKRTDDGTLLPFEVQVGDIILMDKYAGQE
ITIDDEEYVILQSSEIMAVLK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=40.625, Blast_Score=80, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=36.9565217391304, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358317, Length=95, Percent_Identity=37.8947368421053, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CHLPN (P31682)

Other databases:

- EMBL:   M69217
- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   G86507
- PIR:   S19022
- RefSeq:   NP_224343.1
- RefSeq:   NP_300194.1
- RefSeq:   NP_445179.1
- RefSeq:   NP_876412.1
- ProteinModelPortal:   P31682
- SMR:   P31682
- PHCI-2DPAGE:   P31682
- GeneID:   1466819
- GeneID:   894733
- GeneID:   918922
- GeneID:   963255
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0637
- KEGG:   cpn:CPn0135
- KEGG:   cpt:CpB0136
- TIGR:   CP_0637
- HOGENOM:   HBG703377
- OMA:   MAGHAFR
- PhylomeDB:   P31682
- ProtClustDB:   PRK00364
- BioCyc:   CPNE115711:CP_0637-MONOMER
- BioCyc:   CPNE115713:CPN0135-MONOMER
- BioCyc:   CPNE138677:CPJ0135-MONOMER
- BioCyc:   CPNE182082:CPB0136-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 11316; Mature: 11185

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQATTLRIKPLGDRILVKREEEEATARGGIILPDTAKKKQDRAEVLVLGTGKRTDDGT
CCCCCEEEEEEECCCEEEEEECCCCHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCC
LLPFEVQVGDIILMDKYAGQEITIDDEEYVILQSSEIMAVLK
EEEEEEEECCEEEEECCCCCEEEECCCCEEEEECCCEEEEEC
>Mature Secondary Structure 
SDQATTLRIKPLGDRILVKREEEEATARGGIILPDTAKKKQDRAEVLVLGTGKRTDDGT
CCCCEEEEEEECCCEEEEEECCCCHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCC
LLPFEVQVGDIILMDKYAGQEITIDDEEYVILQSSEIMAVLK
EEEEEEEECCEEEEECCCCCEEEECCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1682266; 10192388; 10684935; 10871362