Click here to switch to the map view.

The map label for this gene is atsA

Identifier: 15835562

GI number: 15835562

Start: 37352

End: 38275

Strand: Reverse

Name: atsA

Synonym: CPj0025

Alternate gene names: 15835562

Gene position: 38275-37352 (Counterclockwise)

Preceding gene: 15835563

Following gene: 15835561

Centisome position: 3.12

GC content: 43.18

Gene sequence:

>924_bases
ATGAGTTCTAGAGAGTTAATTATTTTAGGGTGCTCGAGCCAACAGCCTACACGAACACGCAATCAAGGAGCCTACCTATT
TCGCTGGAATGGTGAGGGTCTACTTTTTGATCCTGGTGAAGGCACTCAAAGGCAATTCATCTTTGCAAATATTGCTCCTA
CAACAGTCAATAGAATTTTTGTGAGTCATTTCCATGGAGATCATTGTTTGGGTCTAGGCTCCATGTTGATGCGTCTTAAC
TTGGACAAGGTTTCGCACCCTATCCATTGCTACTATCCTGCTTCAGGGAAAAAATACTTTGACCGCTTACGTTATGGAAC
AATTTATCACGAAACCATCCAGGTGGTGGAGCATCCAATCTCTGAGGAAGGAATTGTCGAAGATTTTGGTAGTTTTCGTA
TTGAAGCACAGCGACTCCAACACCAAGTAGACACTTTAGGATGGAGAATCACGGAACCAGACACTATAAAATTTCTTCCT
AAAGAGCTGGAATCTCGAGGCATTCGTGGTCTGATTATCCAAGATCTTATTCGTGACCAAGAAATTTCGATAGGCGGTTC
TACGGTATATCTTAGTGATGTTAGCTACGTCCGCAAGGGGGATAGCATTGCGATTATTGCGGATACTTTGCCTTGCCAAG
CTGCTATAGATCTCGCAAAAAATAGCTGCATGATGTTGTGTGAAAGCACCTACCTCGAACAGCACCGCCATCTTGCTGAG
AGCCATTTTCATATGACTGCAAAACAAGCGGCGACTCTTGCGAAACGTGCCGCAACACAAAAGCTTATTCTCACACACTT
CTCGGCACGTTACTTAAATCTGGATGATTTTTATAAAGAAGCCTCGGCAGTATTTCCTAATGTGTCCGTAGCACAAGAAT
ATCGCAGCTACCCCTTTCCGAAAAATCCTCTTCTAAATAAATAG

Upstream 100 bases:

>100_bases
ACAAAATTTTAAATGATAAAAAAGTTGTCATTCAAAAGTTGTAGTGGCGTATATAATTTCACTTAGTTTATTCTGTGACT
TTTTCTTAAAGTAAATCCTT

Downstream 100 bases:

>100_bases
CTCGGAAAGAATAGTAAGAAGCTAGCCTTCCTAAAGCTAAGAGGAAGTCTTTTTACGATCTTTATTGTAAGGTAAAGAGA
AGTTATGATTGCCTCTATCT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSSRELIILGCSSQQPTRTRNQGAYLFRWNGEGLLFDPGEGTQRQFIFANIAPTTVNRIFVSHFHGDHCLGLGSMLMRLN
LDKVSHPIHCYYPASGKKYFDRLRYGTIYHETIQVVEHPISEEGIVEDFGSFRIEAQRLQHQVDTLGWRITEPDTIKFLP
KELESRGIRGLIIQDLIRDQEISIGGSTVYLSDVSYVRKGDSIAIIADTLPCQAAIDLAKNSCMMLCESTYLEQHRHLAE
SHFHMTAKQAATLAKRAATQKLILTHFSARYLNLDDFYKEASAVFPNVSVAQEYRSYPFPKNPLLNK

Sequences:

>Translated_307_residues
MSSRELIILGCSSQQPTRTRNQGAYLFRWNGEGLLFDPGEGTQRQFIFANIAPTTVNRIFVSHFHGDHCLGLGSMLMRLN
LDKVSHPIHCYYPASGKKYFDRLRYGTIYHETIQVVEHPISEEGIVEDFGSFRIEAQRLQHQVDTLGWRITEPDTIKFLP
KELESRGIRGLIIQDLIRDQEISIGGSTVYLSDVSYVRKGDSIAIIADTLPCQAAIDLAKNSCMMLCESTYLEQHRHLAE
SHFHMTAKQAATLAKRAATQKLILTHFSARYLNLDDFYKEASAVFPNVSVAQEYRSYPFPKNPLLNK
>Mature_306_residues
SSRELIILGCSSQQPTRTRNQGAYLFRWNGEGLLFDPGEGTQRQFIFANIAPTTVNRIFVSHFHGDHCLGLGSMLMRLNL
DKVSHPIHCYYPASGKKYFDRLRYGTIYHETIQVVEHPISEEGIVEDFGSFRIEAQRLQHQVDTLGWRITEPDTIKFLPK
ELESRGIRGLIIQDLIRDQEISIGGSTVYLSDVSYVRKGDSIAIIADTLPCQAAIDLAKNSCMMLCESTYLEQHRHLAES
HFHMTAKQAATLAKRAATQKLILTHFSARYLNLDDFYKEASAVFPNVSVAQEYRSYPFPKNPLLNK

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=321, Percent_Identity=25.8566978193146, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI260166619, Length=314, Percent_Identity=27.3885350318471, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI260166622, Length=314, Percent_Identity=27.3885350318471, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI145553959, Length=314, Percent_Identity=27.3885350318471, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI87082078, Length=308, Percent_Identity=34.0909090909091, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_CHLPN (Q9Z9F6)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86494
- PIR:   H72127
- RefSeq:   NP_224233.1
- RefSeq:   NP_300086.1
- RefSeq:   NP_445293.1
- RefSeq:   NP_876305.1
- ProteinModelPortal:   Q9Z9F6
- SMR:   Q9Z9F6
- GeneID:   1466712
- GeneID:   894854
- GeneID:   918816
- GeneID:   963151
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0751
- KEGG:   cpj:CPj0025
- KEGG:   cpn:CPn0025
- KEGG:   cpt:CpB0029
- TIGR:   CP_0751
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- PhylomeDB:   Q9Z9F6
- ProtClustDB:   PRK00055
- BioCyc:   CPNE115711:CP_0751-MONOMER
- BioCyc:   CPNE115713:CPN0025-MONOMER
- BioCyc:   CPNE138677:CPJ0025-MONOMER
- BioCyc:   CPNE182082:CPB0029-MONOMER
- BRENDA:   3.1.26.11
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 34900; Mature: 34769

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRELIILGCSSQQPTRTRNQGAYLFRWNGEGLLFDPGEGTQRQFIFANIAPTTVNRIF
CCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEECCHHHHHHHH
VSHFHGDHCLGLGSMLMRLNLDKVSHPIHCYYPASGKKYFDRLRYGTIYHETIQVVEHPI
HHHCCCCHHHHHHHHHHHHCHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCC
SEEGIVEDFGSFRIEAQRLQHQVDTLGWRITEPDTIKFLPKELESRGIRGLIIQDLIRDQ
CCCCHHHHHHHHEEHHHHHHHHHHHCCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHCCC
EISIGGSTVYLSDVSYVRKGDSIAIIADTLPCQAAIDLAKNSCMMLCESTYLEQHRHLAE
CEECCCCEEEEECHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SHFHMTAKQAATLAKRAATQKLILTHFSARYLNLDDFYKEASAVFPNVSVAQEYRSYPFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCC
KNPLLNK
CCCCCCC
>Mature Secondary Structure 
SSRELIILGCSSQQPTRTRNQGAYLFRWNGEGLLFDPGEGTQRQFIFANIAPTTVNRIF
CCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEECCHHHHHHHH
VSHFHGDHCLGLGSMLMRLNLDKVSHPIHCYYPASGKKYFDRLRYGTIYHETIQVVEHPI
HHHCCCCHHHHHHHHHHHHCHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCC
SEEGIVEDFGSFRIEAQRLQHQVDTLGWRITEPDTIKFLPKELESRGIRGLIIQDLIRDQ
CCCCHHHHHHHHEEHHHHHHHHHHHCCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHCCC
EISIGGSTVYLSDVSYVRKGDSIAIIADTLPCQAAIDLAKNSCMMLCESTYLEQHRHLAE
CEECCCCEEEEECHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SHFHMTAKQAATLAKRAATQKLILTHFSARYLNLDDFYKEASAVFPNVSVAQEYRSYPFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCC
KNPLLNK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362