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Identifier: 15835340

GI number: 15835340

Start: 861879

End: 863828

Strand: Direct

Name: Not Available

Synonym: TC0725

Alternate gene names: 15835340

Gene position: 861879-863828 (Clockwise)

Preceding gene: 15835339

Following gene: 15835344

Centisome position: 80.33

GC content: 39.54

Gene sequence:

>1950_bases
ATGAAGAGACTCGCTCGTTTTTGTCTTCTAGCCTTAACTTTATTCCCACAACTTGCGTTTTCCTCAGCCCCCCTCCGACA
ACAAGATGTCCGCAAAACCGTAGAAAAATTAGTCGAGCACCATATTGATACAAAACATATTTCTCCCCACATTTTATCGA
GATCTTTGGAAGACTATGCTCGATCATTCGATTCTCATAAAGCATACTTAACCCAAGATGAGGTCCTAACATACGTCTTT
TCAGAAAAAGCGACCCATTCCTTATTTAAACAATACCAAGAAGATAATTTCGCTTCTTTTAGAGAGTTACATACTTGTAT
TCAACAGAGCATTTCCCGGGTAAGAGAGTGGCGTACTGTGTGGTTATCAGATGCTGTTCGCGTCATTCAAGATGCTTCCT
CACATACTATCCCAAAAAAACCAACTACCTGGGGATCTTCTATTGAAGAGGTAAAGCAAAGACAATATGAGCTTCTTCTT
TCCTATGCATCTATCTACCTAGAAGATGCTACAAAAAATCGCTATCAGGGGAAAGAACATGCACTAGTGAGATTATGTAT
TCGCCAGATTGAAAATCACGAAAATCCTTATATAGGAATCAATGACCATGGACTCAAAATGTCTCTTGAAGAAGAGGCCA
ATAGCTTCCATATTCGCATCATTAAATCCATTGCTCATAGTTTAGATGCTCATACAGCCTACTTCAGCAAAGAAGAAGCC
CTTTCTATGCGAGCTCAGCTGGAGAAAGGTATGTGTGGAATAGGGGTAGTTCTGAAAGAAGACATTGATGGTGTAGTTGT
TAAAGAAGTTCTTCCTGGAGGGCCTGCTGATAAAACAGGAAGTCTTCGTGTGGGCGATATTATTTACCGCGTTAATGGGA
AAAATATTGAAAACACCCCTTTTCCTGGAGTTTTAGATTCCCTAAGAGGATTACCAGGATCTTCCGTCACTTTAGATATT
CACAGACAAAACAACGACCATGTCGTTCAACTACGCCGAGAAAAAATTCTCTTAGATAGCCGCCGTGTTGATGTATCCTA
TGAACCTTACGGTGACGGCATTATCGGGAAAATCACCCTACACTCCTTTTATGAAGGAGAAAATCAGATATCTAGTGAAC
AGGATTTACGACGAGCTATTCGAGAACTGCAAGAAAAAAACCTTCTTGGGTTAGTTCTTGATATTCGAGAAAACACCGGA
GGATTTTTATCTCAAGCCATCAAAGTTTCTGGTTTGTTCCTAACCAATGGAGTTGTTGTTGTCTCTCGATATGCGGATGG
ATCTGTAAAACGCTATCGCACGATTTCTCCTCAAAAATTTTATGATGGGCCATTAGCTGTTTTGGTTTCTAAAAGCTCTG
CTTCCGCAGCAGAAATTGTTGCACAAACACTTCAAGACTATGGTGTAGCCCTTATTGTCGGAGATAAACAAACCTATGGG
AAAGGAACCATACAACACCAAACGATTACAGGGAACAACTCTCAAGAAGATTTCTTTAAAGTAACTGTAGGGAGATACTA
TTCTCCTTCAGGGAAATCCACACAACTGGAAGGTGTTAAATCAGATATTGTTATCCCCTCCCGATATGCGGAAGACAATC
TAGGTGAACGTTTTTTAGAATATGCTCTCCCAGCCGATCAATATGAGAATGTTTTGAACGACAATTTAGGAGATCTCGAT
ATCCATATTCGTCCCTGGTTCCAAAAATACTATTCTCCACATTTACAAAAAACCGAGCTTACGTGGAGAGAAATGCTTCC
CCAACTCGTCGAGAACAGTCAGCAGCGTCTTGAAAAAAACAAAAATTTTGAAATTTTTGTTCAACATTTGAAAAAAACAG
ATAAACAAGAACAATCATTTGGAAGCAATGACCTGCAAATGGAAGAGACTGTCAATATTGTTAAAGACATGATTCTTTTG
CAAACTTCATTAAGATCTCCCGCACAATAA

Upstream 100 bases:

>100_bases
AACAACCAGGGACTTGAGGGTTCATAAGACAAAAGCCGACTCAAGTTTGAAAAACTCGTGTCGAAGATACGAATAATCAC
TATTAATAGAGATATTCGTA

Downstream 100 bases:

>100_bases
ATCAGGGGAGGGGGTGGGTTACCCCTCCCCCCCCCTTTTTTTATGCTGTTTAGAAACACATTGAATTTCGGTCTTTGCAT
TTCTAAACAATTTTTTAGCT

Product: tail specific protease precursor, putative

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MKRLARFCLLALTLFPQLAFSSAPLRQQDVRKTVEKLVEHHIDTKHISPHILSRSLEDYARSFDSHKAYLTQDEVLTYVF
SEKATHSLFKQYQEDNFASFRELHTCIQQSISRVREWRTVWLSDAVRVIQDASSHTIPKKPTTWGSSIEEVKQRQYELLL
SYASIYLEDATKNRYQGKEHALVRLCIRQIENHENPYIGINDHGLKMSLEEEANSFHIRIIKSIAHSLDAHTAYFSKEEA
LSMRAQLEKGMCGIGVVLKEDIDGVVVKEVLPGGPADKTGSLRVGDIIYRVNGKNIENTPFPGVLDSLRGLPGSSVTLDI
HRQNNDHVVQLRREKILLDSRRVDVSYEPYGDGIIGKITLHSFYEGENQISSEQDLRRAIRELQEKNLLGLVLDIRENTG
GFLSQAIKVSGLFLTNGVVVVSRYADGSVKRYRTISPQKFYDGPLAVLVSKSSASAAEIVAQTLQDYGVALIVGDKQTYG
KGTIQHQTITGNNSQEDFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDNLGERFLEYALPADQYENVLNDNLGDLD
IHIRPWFQKYYSPHLQKTELTWREMLPQLVENSQQRLEKNKNFEIFVQHLKKTDKQEQSFGSNDLQMEETVNIVKDMILL
QTSLRSPAQ

Sequences:

>Translated_649_residues
MKRLARFCLLALTLFPQLAFSSAPLRQQDVRKTVEKLVEHHIDTKHISPHILSRSLEDYARSFDSHKAYLTQDEVLTYVF
SEKATHSLFKQYQEDNFASFRELHTCIQQSISRVREWRTVWLSDAVRVIQDASSHTIPKKPTTWGSSIEEVKQRQYELLL
SYASIYLEDATKNRYQGKEHALVRLCIRQIENHENPYIGINDHGLKMSLEEEANSFHIRIIKSIAHSLDAHTAYFSKEEA
LSMRAQLEKGMCGIGVVLKEDIDGVVVKEVLPGGPADKTGSLRVGDIIYRVNGKNIENTPFPGVLDSLRGLPGSSVTLDI
HRQNNDHVVQLRREKILLDSRRVDVSYEPYGDGIIGKITLHSFYEGENQISSEQDLRRAIRELQEKNLLGLVLDIRENTG
GFLSQAIKVSGLFLTNGVVVVSRYADGSVKRYRTISPQKFYDGPLAVLVSKSSASAAEIVAQTLQDYGVALIVGDKQTYG
KGTIQHQTITGNNSQEDFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDNLGERFLEYALPADQYENVLNDNLGDLD
IHIRPWFQKYYSPHLQKTELTWREMLPQLVENSQQRLEKNKNFEIFVQHLKKTDKQEQSFGSNDLQMEETVNIVKDMILL
QTSLRSPAQ
>Mature_649_residues
MKRLARFCLLALTLFPQLAFSSAPLRQQDVRKTVEKLVEHHIDTKHISPHILSRSLEDYARSFDSHKAYLTQDEVLTYVF
SEKATHSLFKQYQEDNFASFRELHTCIQQSISRVREWRTVWLSDAVRVIQDASSHTIPKKPTTWGSSIEEVKQRQYELLL
SYASIYLEDATKNRYQGKEHALVRLCIRQIENHENPYIGINDHGLKMSLEEEANSFHIRIIKSIAHSLDAHTAYFSKEEA
LSMRAQLEKGMCGIGVVLKEDIDGVVVKEVLPGGPADKTGSLRVGDIIYRVNGKNIENTPFPGVLDSLRGLPGSSVTLDI
HRQNNDHVVQLRREKILLDSRRVDVSYEPYGDGIIGKITLHSFYEGENQISSEQDLRRAIRELQEKNLLGLVLDIRENTG
GFLSQAIKVSGLFLTNGVVVVSRYADGSVKRYRTISPQKFYDGPLAVLVSKSSASAAEIVAQTLQDYGVALIVGDKQTYG
KGTIQHQTITGNNSQEDFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDNLGERFLEYALPADQYENVLNDNLGDLD
IHIRPWFQKYYSPHLQKTELTWREMLPQLVENSQQRLEKNKNFEIFVQHLKKTDKQEQSFGSNDLQMEETVNIVKDMILL
QTSLRSPAQ

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=471, Percent_Identity=30.1486199575372, Blast_Score=182, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 73864; Mature: 73864

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLARFCLLALTLFPQLAFSSAPLRQQDVRKTVEKLVEHHIDTKHISPHILSRSLEDYA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RSFDSHKAYLTQDEVLTYVFSEKATHSLFKQYQEDNFASFRELHTCIQQSISRVREWRTV
HHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLSDAVRVIQDASSHTIPKKPTTWGSSIEEVKQRQYELLLSYASIYLEDATKNRYQGKEH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALVRLCIRQIENHENPYIGINDHGLKMSLEEEANSFHIRIIKSIAHSLDAHTAYFSKEEA
HHHHHHHHHHHCCCCCEEEECCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
LSMRAQLEKGMCGIGVVLKEDIDGVVVKEVLPGGPADKTGSLRVGDIIYRVNGKNIENTP
HHHHHHHHCCCCCCCEEEECCCCCEEHHHHCCCCCCCCCCCEEECEEEEEECCCCCCCCC
FPGVLDSLRGLPGSSVTLDIHRQNNDHVVQLRREKILLDSRRVDVSYEPYGDGIIGKITL
CCHHHHHHCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCCEEEEECCCCCCCEEEEEE
HSFYEGENQISSEQDLRRAIRELQEKNLLGLVLDIRENTGGFLSQAIKVSGLFLTNGVVV
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCEEEECCEEE
VSRYADGSVKRYRTISPQKFYDGPLAVLVSKSSASAAEIVAQTLQDYGVALIVGDKQTYG
EEECCCCCCHHHCCCCCCHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCC
KGTIQHQTITGNNSQEDFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDNLGERFLE
CCCEEEEEECCCCCCCCCEEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
YALPADQYENVLNDNLGDLDIHIRPWFQKYYSPHLQKTELTWREMLPQLVENSQQRLEKN
HCCCHHHHHHHHCCCCCCEEEEEEHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHC
KNFEIFVQHLKKTDKQEQSFGSNDLQMEETVNIVKDMILLQTSLRSPAQ
CCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRLARFCLLALTLFPQLAFSSAPLRQQDVRKTVEKLVEHHIDTKHISPHILSRSLEDYA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RSFDSHKAYLTQDEVLTYVFSEKATHSLFKQYQEDNFASFRELHTCIQQSISRVREWRTV
HHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLSDAVRVIQDASSHTIPKKPTTWGSSIEEVKQRQYELLLSYASIYLEDATKNRYQGKEH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALVRLCIRQIENHENPYIGINDHGLKMSLEEEANSFHIRIIKSIAHSLDAHTAYFSKEEA
HHHHHHHHHHHCCCCCEEEECCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
LSMRAQLEKGMCGIGVVLKEDIDGVVVKEVLPGGPADKTGSLRVGDIIYRVNGKNIENTP
HHHHHHHHCCCCCCCEEEECCCCCEEHHHHCCCCCCCCCCCEEECEEEEEECCCCCCCCC
FPGVLDSLRGLPGSSVTLDIHRQNNDHVVQLRREKILLDSRRVDVSYEPYGDGIIGKITL
CCHHHHHHCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCCEEEEECCCCCCCEEEEEE
HSFYEGENQISSEQDLRRAIRELQEKNLLGLVLDIRENTGGFLSQAIKVSGLFLTNGVVV
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCEEEECCEEE
VSRYADGSVKRYRTISPQKFYDGPLAVLVSKSSASAAEIVAQTLQDYGVALIVGDKQTYG
EEECCCCCCHHHCCCCCCHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCC
KGTIQHQTITGNNSQEDFFKVTVGRYYSPSGKSTQLEGVKSDIVIPSRYAEDNLGERFLE
CCCEEEEEECCCCCCCCCEEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
YALPADQYENVLNDNLGDLDIHIRPWFQKYYSPHLQKTELTWREMLPQLVENSQQRLEKN
HCCCHHHHHHHHCCCCCCEEEEEEHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHC
KNFEIFVQHLKKTDKQEQSFGSNDLQMEETVNIVKDMILLQTSLRSPAQ
CCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]