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The map label for this gene is fabD

Identifier: 15835127

GI number: 15835127

Start: 615155

End: 616081

Strand: Reverse

Name: fabD

Synonym: TC0509

Alternate gene names: 15835127

Gene position: 616081-615155 (Counterclockwise)

Preceding gene: 15835128

Following gene: 15835126

Centisome position: 57.42

GC content: 40.13

Gene sequence:

>927_bases
ATGGAGCGTATAGGGTTGCTATTCCCTGGTCAGGGTAGTCAATTCGTTGGAATGGGCAAGGATCTTTATCAACAGTATCC
AGAAGTGACACAGTTGTTCGCTCAAGCAGATGAGTTTCTTGGATTCTCTTTGTCTTCCATTATGTTCGAAGGTCCAGAAG
AAACTTTATTGAAAACAACAAATAGTCAGTTAGCTATTTATCTTCATAGTTTGGCTGTATTAGAGATTTTATCAGCACGC
TGTTCTTTTAACCCTGTTTTGGTTTCTGGTCTAAGTTTAGGAGAGTATACTGCTTTAACGGCATCTAAACGTATAAGTTT
GGAAGATGGACTTCGTGTTGTACAAAAGCGAGCTGAACTTATGAATGCAGCTTGTGAACAGTCCCTAGGAGCGATGGCTG
CAGTTTTAGGCTTAACTGCAGATATTGTGCTGCCAGCTTTAGAGTCTTTAGGTAGTGGGATTTGGGTGGCTAATTACAAT
GCTCCCAAGCAGATTGTCATCGCAGGGGTTCGGGATAAAGTAGAAGAAGCTGCTGTAGTTCTCCGAGAGTTAGGAGCCAA
AAAAGTAGTCATGTTAAAAGTATCTGGAGCGTTTCATACTCCACTTATGCAATCTGCTCAAGACGAATTGGCTCCCTATT
TATATCAGTTAGCTATCAGAGATTCGAGCATAGCATTCGCGTCTAATGTAGTAGGGGAGTTGGTACAAGAGAGCGAAATG
ATTCGTTCTTTAATGGTTAAACAAATGACTTCTCCAACGTTATGGTATCAAACTTGTTTTCAAATTGATTCCAAAGTAGA
TTTATTTCTTGAACTTGGATCTGGAAATGTTTTGACGGGGCTTTGTCGGTCTATAGGACTTGCCTCTCCTTGTAAACATT
TAGGATCTGTAGAAGATATAGAGAATTTTTGTCGGAGTTTTGAATGA

Upstream 100 bases:

>100_bases
GATATTCATTCGAAAGAGCGACTATTGTTAGTTGCCTTTGGAGGGGGATTGTCTTGGGGAGCTGTGATTTTACAGCAAAT
GTAATAGAGGAGACCATGTT

Downstream 100 bases:

>100_bases
ATAGCTTATTGGTAAACAAAGCTGCAATTGTAACTGGCGGTTCTAGGGGAATTGGTTTTGGCATAGCAAAACTATTCGCT
GAGCATGGGGCTAATGTTCA

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MERIGLLFPGQGSQFVGMGKDLYQQYPEVTQLFAQADEFLGFSLSSIMFEGPEETLLKTTNSQLAIYLHSLAVLEILSAR
CSFNPVLVSGLSLGEYTALTASKRISLEDGLRVVQKRAELMNAACEQSLGAMAAVLGLTADIVLPALESLGSGIWVANYN
APKQIVIAGVRDKVEEAAVVLRELGAKKVVMLKVSGAFHTPLMQSAQDELAPYLYQLAIRDSSIAFASNVVGELVQESEM
IRSLMVKQMTSPTLWYQTCFQIDSKVDLFLELGSGNVLTGLCRSIGLASPCKHLGSVEDIENFCRSFE

Sequences:

>Translated_308_residues
MERIGLLFPGQGSQFVGMGKDLYQQYPEVTQLFAQADEFLGFSLSSIMFEGPEETLLKTTNSQLAIYLHSLAVLEILSAR
CSFNPVLVSGLSLGEYTALTASKRISLEDGLRVVQKRAELMNAACEQSLGAMAAVLGLTADIVLPALESLGSGIWVANYN
APKQIVIAGVRDKVEEAAVVLRELGAKKVVMLKVSGAFHTPLMQSAQDELAPYLYQLAIRDSSIAFASNVVGELVQESEM
IRSLMVKQMTSPTLWYQTCFQIDSKVDLFLELGSGNVLTGLCRSIGLASPCKHLGSVEDIENFCRSFE
>Mature_308_residues
MERIGLLFPGQGSQFVGMGKDLYQQYPEVTQLFAQADEFLGFSLSSIMFEGPEETLLKTTNSQLAIYLHSLAVLEILSAR
CSFNPVLVSGLSLGEYTALTASKRISLEDGLRVVQKRAELMNAACEQSLGAMAAVLGLTADIVLPALESLGSGIWVANYN
APKQIVIAGVRDKVEEAAVVLRELGAKKVVMLKVSGAFHTPLMQSAQDELAPYLYQLAIRDSSIAFASNVVGELVQESEM
IRSLMVKQMTSPTLWYQTCFQIDSKVDLFLELGSGNVLTGLCRSIGLASPCKHLGSVEDIENFCRSFE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=34.3333333333333, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=42.5925925925926, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=35.0694444444444, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71984332, Length=297, Percent_Identity=29.6296296296296, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=289, Percent_Identity=27.3356401384083, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24665753, Length=272, Percent_Identity=37.1323529411765, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33473; Mature: 33473

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIGLLFPGQGSQFVGMGKDLYQQYPEVTQLFAQADEFLGFSLSSIMFEGPEETLLKTT
CCCCEEEECCCCCCEECCCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCC
NSQLAIYLHSLAVLEILSARCSFNPVLVSGLSLGEYTALTASKRISLEDGLRVVQKRAEL
CCHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MNAACEQSLGAMAAVLGLTADIVLPALESLGSGIWVANYNAPKQIVIAGVRDKVEEAAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECHHHHHHHHHHH
LRELGAKKVVMLKVSGAFHTPLMQSAQDELAPYLYQLAIRDSSIAFASNVVGELVQESEM
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IRSLMVKQMTSPTLWYQTCFQIDSKVDLFLELGSGNVLTGLCRSIGLASPCKHLGSVEDI
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCHHHH
ENFCRSFE
HHHHHCCC
>Mature Secondary Structure
MERIGLLFPGQGSQFVGMGKDLYQQYPEVTQLFAQADEFLGFSLSSIMFEGPEETLLKTT
CCCCEEEECCCCCCEECCCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCC
NSQLAIYLHSLAVLEILSARCSFNPVLVSGLSLGEYTALTASKRISLEDGLRVVQKRAEL
CCHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MNAACEQSLGAMAAVLGLTADIVLPALESLGSGIWVANYNAPKQIVIAGVRDKVEEAAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECHHHHHHHHHHH
LRELGAKKVVMLKVSGAFHTPLMQSAQDELAPYLYQLAIRDSSIAFASNVVGELVQESEM
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IRSLMVKQMTSPTLWYQTCFQIDSKVDLFLELGSGNVLTGLCRSIGLASPCKHLGSVEDI
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCHHHH
ENFCRSFE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]