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Identifier: 15835119

GI number: 15835119

Start: 606511

End: 607758

Strand: Direct

Name: Not Available

Synonym: TC0501

Alternate gene names: 15835119

Gene position: 606511-607758 (Clockwise)

Preceding gene: 15835111

Following gene: 15835120

Centisome position: 56.53

GC content: 40.62

Gene sequence:

>1248_bases
ATGCGCTCTCCTTGGAAATTTTTATTGTCTCTTGGAAAAAGCAATTTTTTGCTTAGTTTAAGCATATTACTTGGACTTAT
TCTTGGGTGGCCCCATCTTCCTTTTATATCCTTTAGTGCAGAGATTGTTTCCGCCGCCTTCTTGAAGCTTTTGAAACTTT
TGAGCCTACCTCTTGTATTTTTTGCCATTGGCTCCACAATCACCTCAATTAATGACCTGCGGTCCATGATAGCTGTTGTC
AGAGCTTCTTTATACTATACCCTGCTAACAACGATTATCTCCGCTGGTATAGCGCTAGCACTGTTCATCCTCATTAAGCC
TTCAGTAAACCTTACAGGGCTCAACCTAAATGTAGGAGCCAATTCAACCGGTTATCTGGCCGTTCTATCAAAAACAATAC
CAGGGAATATTTTAGAACCTTTCTTAGAAAGTAATGTCATAGCCGCCGCGTTTTTGTCCTTCCTACTGTCCTTTTTTTCC
CTTTCTCTTCCAGAAGAAGAACGCTTATTTATCCGAAACGCTTTCAATACCCTCTTCTCTCTGCTGCTTAACATAGCTAA
AGGCATTCTAAAAATGCTTCCTTTGGCAACTTTCTCCTTCTCACTTCTTTTTGTTAGAGAAATGCGAACAGGAAGCTTAG
AACTTTCCTCTTTTGGAGGGTACCTATTTTGCATTGTTGGGGCTAACTGCCTTCAAGGATTTGTCATCCTCCCCCTACTT
CTCAAAATAAAGGGGATTTCCCCTATAAGGACATTCAGACTTATGTCTCGTCCCCTAGCTACAGCATTTTTTTCTAAATC
TTCTGCAGCAACATTACCCTTGACTATGGAAGTCGCTGAGGAAAACTTGCACATCCAACCGACCATCTCTCGGTTTGTTT
TCCCCCTGTGCTCTGTAATTAACATGAATGCTTGCGCTGCATTTATTCTAATAACTGTACTTTTTATTGGAGTCTCTAAT
GGGGTCGTTTTTTCCCCCTTATCGCTTATTAGCTGGGTTTTTATCGCTACTTTAGCTGCCGTAGGAAATGCTGGGGTTCC
TATGGGGTGCTACTTTCTAGCATCATCTTTGTTATCCTCTATGAATATCCCCTTAGGTCTTCTCGGTCTTATTCTTCCAG
CATACGCTTTATTAGACATGTTAGAGACTTTGATCAATGTTTGGTCTGATTGCTGCGTCGTCTCCATAATAAATAAAAAA
TTTACCAACACAAAAGAGTTTCCGTCTTGTTCTCATTCCTACAAATAA

Upstream 100 bases:

>100_bases
TACTTGTAAAGAGTCCTCAATGTTGCAAAAAAAACCCCTCCTTTCTTACATTTCTTGCATTTAGTCCCAAAAGACTCTCT
ACTTAAAAAATTGAGGTATA

Downstream 100 bases:

>100_bases
GAATAAGTCCCTTGAGATAAAATCTTTTACAGATCAAAAACCATCGCGCTTGTTAAGGGTGGAGATGAAAATGTTTTTGG
GCTACCATCGAATGTCTTTG

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MRSPWKFLLSLGKSNFLLSLSILLGLILGWPHLPFISFSAEIVSAAFLKLLKLLSLPLVFFAIGSTITSINDLRSMIAVV
RASLYYTLLTTIISAGIALALFILIKPSVNLTGLNLNVGANSTGYLAVLSKTIPGNILEPFLESNVIAAAFLSFLLSFFS
LSLPEEERLFIRNAFNTLFSLLLNIAKGILKMLPLATFSFSLLFVREMRTGSLELSSFGGYLFCIVGANCLQGFVILPLL
LKIKGISPIRTFRLMSRPLATAFFSKSSAATLPLTMEVAEENLHIQPTISRFVFPLCSVINMNACAAFILITVLFIGVSN
GVVFSPLSLISWVFIATLAAVGNAGVPMGCYFLASSLLSSMNIPLGLLGLILPAYALLDMLETLINVWSDCCVVSIINKK
FTNTKEFPSCSHSYK

Sequences:

>Translated_415_residues
MRSPWKFLLSLGKSNFLLSLSILLGLILGWPHLPFISFSAEIVSAAFLKLLKLLSLPLVFFAIGSTITSINDLRSMIAVV
RASLYYTLLTTIISAGIALALFILIKPSVNLTGLNLNVGANSTGYLAVLSKTIPGNILEPFLESNVIAAAFLSFLLSFFS
LSLPEEERLFIRNAFNTLFSLLLNIAKGILKMLPLATFSFSLLFVREMRTGSLELSSFGGYLFCIVGANCLQGFVILPLL
LKIKGISPIRTFRLMSRPLATAFFSKSSAATLPLTMEVAEENLHIQPTISRFVFPLCSVINMNACAAFILITVLFIGVSN
GVVFSPLSLISWVFIATLAAVGNAGVPMGCYFLASSLLSSMNIPLGLLGLILPAYALLDMLETLINVWSDCCVVSIINKK
FTNTKEFPSCSHSYK
>Mature_415_residues
MRSPWKFLLSLGKSNFLLSLSILLGLILGWPHLPFISFSAEIVSAAFLKLLKLLSLPLVFFAIGSTITSINDLRSMIAVV
RASLYYTLLTTIISAGIALALFILIKPSVNLTGLNLNVGANSTGYLAVLSKTIPGNILEPFLESNVIAAAFLSFLLSFFS
LSLPEEERLFIRNAFNTLFSLLLNIAKGILKMLPLATFSFSLLFVREMRTGSLELSSFGGYLFCIVGANCLQGFVILPLL
LKIKGISPIRTFRLMSRPLATAFFSKSSAATLPLTMEVAEENLHIQPTISRFVFPLCSVINMNACAAFILITVLFIGVSN
GVVFSPLSLISWVFIATLAAVGNAGVPMGCYFLASSLLSSMNIPLGLLGLILPAYALLDMLETLINVWSDCCVVSIINKK
FTNTKEFPSCSHSYK

Specific function: Unknown

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468564, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223468566, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5032093, Length=362, Percent_Identity=26.5193370165746, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI21314632, Length=296, Percent_Identity=27.3648648648649, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI66773030, Length=239, Percent_Identity=29.2887029288703, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI40254478, Length=459, Percent_Identity=24.1830065359477, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194239697, Length=240, Percent_Identity=30, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4827012, Length=253, Percent_Identity=25.6916996047431, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI169790839, Length=142, Percent_Identity=31.6901408450704, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301601644, Length=141, Percent_Identity=32.6241134751773, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788024, Length=400, Percent_Identity=25.25, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790514, Length=376, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789947, Length=399, Percent_Identity=22.3057644110276, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=461, Percent_Identity=26.2472885032538, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193206505, Length=198, Percent_Identity=30.3030303030303, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206654, Length=418, Percent_Identity=24.1626794258373, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17541374, Length=145, Percent_Identity=35.1724137931034, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983106, Length=178, Percent_Identity=30.3370786516854, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=178, Percent_Identity=30.3370786516854, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=393, Percent_Identity=23.4096692111959, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583025, Length=411, Percent_Identity=24.8175182481752, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137668, Length=411, Percent_Identity=24.8175182481752, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583023, Length=411, Percent_Identity=24.8175182481752, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45071; Mature: 45071

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPWKFLLSLGKSNFLLSLSILLGLILGWPHLPFISFSAEIVSAAFLKLLKLLSLPLVF
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGSTITSINDLRSMIAVVRASLYYTLLTTIISAGIALALFILIKPSVNLTGLNLNVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NSTGYLAVLSKTIPGNILEPFLESNVIAAAFLSFLLSFFSLSLPEEERLFIRNAFNTLFS
CCCCHHEEHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LLLNIAKGILKMLPLATFSFSLLFVREMRTGSLELSSFGGYLFCIVGANCLQGFVILPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCEEHEEHHHHHHHHHHHHHHH
LKIKGISPIRTFRLMSRPLATAFFSKSSAATLPLTMEVAEENLHIQPTISRFVFPLCSVI
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHEEHHCCCCCCHHHHHHHHHHHHHH
NMNACAAFILITVLFIGVSNGVVFSPLSLISWVFIATLAAVGNAGVPMGCYFLASSLLSS
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MNIPLGLLGLILPAYALLDMLETLINVWSDCCVVSIINKKFTNTKEFPSCSHSYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSPWKFLLSLGKSNFLLSLSILLGLILGWPHLPFISFSAEIVSAAFLKLLKLLSLPLVF
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGSTITSINDLRSMIAVVRASLYYTLLTTIISAGIALALFILIKPSVNLTGLNLNVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NSTGYLAVLSKTIPGNILEPFLESNVIAAAFLSFLLSFFSLSLPEEERLFIRNAFNTLFS
CCCCHHEEHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LLLNIAKGILKMLPLATFSFSLLFVREMRTGSLELSSFGGYLFCIVGANCLQGFVILPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCEEHEEHHHHHHHHHHHHHHH
LKIKGISPIRTFRLMSRPLATAFFSKSSAATLPLTMEVAEENLHIQPTISRFVFPLCSVI
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHEEHHCCCCCCHHHHHHHHHHHHHH
NMNACAAFILITVLFIGVSNGVVFSPLSLISWVFIATLAAVGNAGVPMGCYFLASSLLSS
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MNIPLGLLGLILPAYALLDMLETLINVWSDCCVVSIINKKFTNTKEFPSCSHSYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]