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The map label for this gene is kdtA

Identifier: 15835098

GI number: 15835098

Start: 582997

End: 584289

Strand: Reverse

Name: kdtA

Synonym: TC0480

Alternate gene names: 15835098

Gene position: 584289-582997 (Counterclockwise)

Preceding gene: 15835099

Following gene: 15835086

Centisome position: 54.46

GC content: 38.75

Gene sequence:

>1293_bases
ATGAGACGTTGGCTAACTTCCCGTCTTTATGATGCTTTTTTAGTTGCTGCTTTCTTAGCAGCAGCACCACGCATTTTTTA
TAAAGTAGTCTTTCACGGGAAGTATATCAATTCTTGGAAAATTCGATTTGGAGTAGAAAAACCACAAGTTAAGGGGGAAG
GTCCCTTGGTTTGGTTCCATGGGGCATCGGTAGGAGAGGTTTCTCTTTTGGAGCCCCTTCTTAAGAAGTGGAGACAAGAA
TTCCCTGATTGGCGTTTTGTGGTTACGGCATGTTCTGAGGCTGGTGTATATACTGCGCAACGTTTGTATGCTCCGCTCGG
GGCAACAGTGTTTGTTTTGCCCCTCGATCTAAGCTGTATTATCAATCCTGTTGTTCGTAGTCTATCTCCTCAGGTGGTTA
TTTTTTCAGAAGGAGATTGTTGGCTCCATTTTTTAATGGGAGCCAAGAAGTTAGGAGCTAAGGCTTTTTTGATTAATGGC
AAACTTTCAGAAAATTCCTGTAAGCGTTTTGCTTTTTTAAAGCGTTTAGGAAGAAGTTACTTTGCTCCATTAGACTTATT
GGTTTTGCAAGACAAGGTGTATAAACAACGGTTTATGCAGATAGGTATTCCTGAAGATAAAATACAAATTTCAGGGAACT
TGAAAACATTCATAGAAACAGAGACTTCTATAAATAATAGAAGCCTTTGGAGAAAAAAGTTAAAATTATCTCCCAGTGAC
CGCTTGATTGTTTTAGGATCTATGCATCCCAAAGACGTTGAGGTTTGGGCAGATGTTGCTCAACATTTCAACAAATTTTC
TACAAAAATTTTGTGGGTGCCTAGACATCTTGAAAAGCTAAAAGAACATGCGAGGTTATTAGAAAAAGCTGGGATCTCGT
TTGGTTTGTGGAGTAAAGAAGATTCTTTGCTTCAGTATGATTCTTTAATTGTGGATGCCATGGGGATTTTAAAAGATCTC
TATTCGGCAGCAGACCTTGCATTTGTAGGAGGGACTTTTGATCCCTTAGTGGGAGGGCATAATTTATTAGAGCCTCTTCA
AAAAGAGGTGCCACTTATGTTTGGTCCACATATCCATTCTCAGTCTGTTTTAGCAGAACTTTTGCGAACAAAAGAAGTTG
GAGTTAGTGTAGACAAGGAGAATCTTTTAGAAGCAGTCGAAAATCTTCTTGAAGACGAAAAGAAACGTCAAGCTTACATT
GAAAGAGGGAAAAGCTTTTTGAAAAACGCAGGAACAAGTTTTGAACATACATGGGAAATATTAAAGAGCCAAATTGCTTG
CATAAAAATCTAA

Upstream 100 bases:

>100_bases
TTGTTGCATTGGCTAAAGAAGCTGTATCTAAATATTTGGAAGGTGGGGTAGTGAGAAAGACTATTTTTGTTCTGAACCGA
CTAGTTAACTTCGTGATATA

Downstream 100 bases:

>100_bases
GAATATGATAGTCTTAGACTTTCTATCGCGGGATAGAGTAGTGGTCATCTCGTTGGGCTCATAACCCAAAGGTCGGAGGT
TCGAATCCTTCTCCCGCTAT

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRRWLTSRLYDAFLVAAFLAAAPRIFYKVVFHGKYINSWKIRFGVEKPQVKGEGPLVWFHGASVGEVSLLEPLLKKWRQE
FPDWRFVVTACSEAGVYTAQRLYAPLGATVFVLPLDLSCIINPVVRSLSPQVVIFSEGDCWLHFLMGAKKLGAKAFLING
KLSENSCKRFAFLKRLGRSYFAPLDLLVLQDKVYKQRFMQIGIPEDKIQISGNLKTFIETETSINNRSLWRKKLKLSPSD
RLIVLGSMHPKDVEVWADVAQHFNKFSTKILWVPRHLEKLKEHARLLEKAGISFGLWSKEDSLLQYDSLIVDAMGILKDL
YSAADLAFVGGTFDPLVGGHNLLEPLQKEVPLMFGPHIHSQSVLAELLRTKEVGVSVDKENLLEAVENLLEDEKKRQAYI
ERGKSFLKNAGTSFEHTWEILKSQIACIKI

Sequences:

>Translated_430_residues
MRRWLTSRLYDAFLVAAFLAAAPRIFYKVVFHGKYINSWKIRFGVEKPQVKGEGPLVWFHGASVGEVSLLEPLLKKWRQE
FPDWRFVVTACSEAGVYTAQRLYAPLGATVFVLPLDLSCIINPVVRSLSPQVVIFSEGDCWLHFLMGAKKLGAKAFLING
KLSENSCKRFAFLKRLGRSYFAPLDLLVLQDKVYKQRFMQIGIPEDKIQISGNLKTFIETETSINNRSLWRKKLKLSPSD
RLIVLGSMHPKDVEVWADVAQHFNKFSTKILWVPRHLEKLKEHARLLEKAGISFGLWSKEDSLLQYDSLIVDAMGILKDL
YSAADLAFVGGTFDPLVGGHNLLEPLQKEVPLMFGPHIHSQSVLAELLRTKEVGVSVDKENLLEAVENLLEDEKKRQAYI
ERGKSFLKNAGTSFEHTWEILKSQIACIKI
>Mature_430_residues
MRRWLTSRLYDAFLVAAFLAAAPRIFYKVVFHGKYINSWKIRFGVEKPQVKGEGPLVWFHGASVGEVSLLEPLLKKWRQE
FPDWRFVVTACSEAGVYTAQRLYAPLGATVFVLPLDLSCIINPVVRSLSPQVVIFSEGDCWLHFLMGAKKLGAKAFLING
KLSENSCKRFAFLKRLGRSYFAPLDLLVLQDKVYKQRFMQIGIPEDKIQISGNLKTFIETETSINNRSLWRKKLKLSPSD
RLIVLGSMHPKDVEVWADVAQHFNKFSTKILWVPRHLEKLKEHARLLEKAGISFGLWSKEDSLLQYDSLIVDAMGILKDL
YSAADLAFVGGTFDPLVGGHNLLEPLQKEVPLMFGPHIHSQSVLAELLRTKEVGVSVDKENLLEAVENLLEDEKKRQAYI
ERGKSFLKNAGTSFEHTWEILKSQIACIKI

Specific function: Transfers three 3-deoxy-D-mono octulonic acid (KDO) individually from CMP-KDO to a tetraacyldisaccharide 1,4'- bisphosphate precursor of lipid A (lipid IVA)

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family

Homologues:

Organism=Escherichia coli, GI1790064, Length=373, Percent_Identity=27.0777479892761, Blast_Score=131, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDTA_CHLMU (Q9PKI5)

Other databases:

- EMBL:   AE002160
- PIR:   F81698
- RefSeq:   NP_296857.1
- ProteinModelPortal:   Q9PKI5
- GeneID:   1245838
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0480
- TIGR:   TC_0480
- HOGENOM:   HBG413990
- OMA:   HPQRFDE
- PhylomeDB:   Q9PKI5
- ProtClustDB:   PRK05749
- BioCyc:   CMUR243161:TC_0480-MONOMER
- InterPro:   IPR007507

Pfam domain/function: PF04413 Glycos_transf_N

EC number: 2.-.-.-

Molecular weight: Translated: 48859; Mature: 48859

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xca7f63c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRWLTSRLYDAFLVAAFLAAAPRIFYKVVFHGKYINSWKIRFGVEKPQVKGEGPLVWFH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCEEEEC
GASVGEVSLLEPLLKKWRQEFPDWRFVVTACSEAGVYTAQRLYAPLGATVFVLPLDLSCI
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCHHHH
INPVVRSLSPQVVIFSEGDCWLHFLMGAKKLGAKAFLINGKLSENSCKRFAFLKRLGRSY
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FAPLDLLVLQDKVYKQRFMQIGIPEDKIQISGNLKTFIETETSINNRSLWRKKLKLSPSD
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCC
RLIVLGSMHPKDVEVWADVAQHFNKFSTKILWVPRHLEKLKEHARLLEKAGISFGLWSKE
CEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCCCEECCCCC
DSLLQYDSLIVDAMGILKDLYSAADLAFVGGTFDPLVGGHNLLEPLQKEVPLMFGPHIHS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCCEEECCCCCH
QSVLAELLRTKEVGVSVDKENLLEAVENLLEDEKKRQAYIERGKSFLKNAGTSFEHTWEI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LKSQIACIKI
HHHHHHHCCH
>Mature Secondary Structure
MRRWLTSRLYDAFLVAAFLAAAPRIFYKVVFHGKYINSWKIRFGVEKPQVKGEGPLVWFH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCEEEEC
GASVGEVSLLEPLLKKWRQEFPDWRFVVTACSEAGVYTAQRLYAPLGATVFVLPLDLSCI
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCHHHH
INPVVRSLSPQVVIFSEGDCWLHFLMGAKKLGAKAFLINGKLSENSCKRFAFLKRLGRSY
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FAPLDLLVLQDKVYKQRFMQIGIPEDKIQISGNLKTFIETETSINNRSLWRKKLKLSPSD
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCC
RLIVLGSMHPKDVEVWADVAQHFNKFSTKILWVPRHLEKLKEHARLLEKAGISFGLWSKE
CEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCCCEECCCCC
DSLLQYDSLIVDAMGILKDLYSAADLAFVGGTFDPLVGGHNLLEPLQKEVPLMFGPHIHS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCCEEECCCCCH
QSVLAELLRTKEVGVSVDKENLLEAVENLLEDEKKRQAYIERGKSFLKNAGTSFEHTWEI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LKSQIACIKI
HHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935