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The map label for this gene is cobU [H]

Identifier: 158338827

GI number: 158338827

Start: 5819288

End: 5819863

Strand: Reverse

Name: cobU [H]

Synonym: AM1_5740

Alternate gene names: 158338827

Gene position: 5819863-5819288 (Counterclockwise)

Preceding gene: 158338829

Following gene: 158338826

Centisome position: 89.49

GC content: 50.0

Gene sequence:

>576_bases
ATGGATAATCGGCATTTAGTTTTAGTGACAGGACCAGCCCGCTCCGGTAAGAGCGAATGGGCTGAAAACTTGGCAGGTCA
GTCTAATAGGTCGGTGATATATGTGGCCACGGCAGCAGACTATCCTGAAGATGAGGAATGGCAAACGCGGATCCAAGCCC
ATCAGCAGCGCCGTCCTACAAATTGGCAAACCATACATGCCCCGATGGATTTAGCCAAGACAATTCAAGCCCAGCCTAAA
TCGATTTGTTTGCTGATTGACTCCTTAGGAACTTGGCTGGCCAATATTTTGGACCAGGAGGCTGAATTGTGGGCAGTTAC
TTTAGAGACGTTGTTGAAAGCCATGACACAAGCGGAGTGCCAAATTATTGTTGTGGGTGAGGAGACGGGCTGGGGGGTGG
TGCCAGGGTATCCCTTAGGGAGACGATTTCGCGATCGCATGGGGGAATTGCTGCGTCAGATTGGGGCGATCTCGGATCAA
GTTTATTTAGTGTCGGCGGGTTATGCCCTAAATCTTAAAGCTTTAGGGATTTATGTTACTCCGATGGTCCCCCTTGACGG
TCCCAAAAGAGACTGA

Upstream 100 bases:

>100_bases
CAAAGTACGAAGTTTCGGAGCAGAAAGGCCGACTCTAAAGATTTTGCGTAGATTTTTGAGAATGTGTTGATGTGTTATGC
AAACAAATGCTGGAAAGGCT

Downstream 100 bases:

>100_bases
CTATAAGGTGTTGAAGTGTTTTTAGCGCCATCTGGAGACTGATGTCATTATCCTAAAATTTGAGTTAGAGTCACCCTAAC
CGTGTGTGATCCAAAAGGGG

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MDNRHLVLVTGPARSGKSEWAENLAGQSNRSVIYVATAADYPEDEEWQTRIQAHQQRRPTNWQTIHAPMDLAKTIQAQPK
SICLLIDSLGTWLANILDQEAELWAVTLETLLKAMTQAECQIIVVGEETGWGVVPGYPLGRRFRDRMGELLRQIGAISDQ
VYLVSAGYALNLKALGIYVTPMVPLDGPKRD

Sequences:

>Translated_191_residues
MDNRHLVLVTGPARSGKSEWAENLAGQSNRSVIYVATAADYPEDEEWQTRIQAHQQRRPTNWQTIHAPMDLAKTIQAQPK
SICLLIDSLGTWLANILDQEAELWAVTLETLLKAMTQAECQIIVVGEETGWGVVPGYPLGRRFRDRMGELLRQIGAISDQ
VYLVSAGYALNLKALGIYVTPMVPLDGPKRD
>Mature_191_residues
MDNRHLVLVTGPARSGKSEWAENLAGQSNRSVIYVATAADYPEDEEWQTRIQAHQQRRPTNWQTIHAPMDLAKTIQAQPK
SICLLIDSLGTWLANILDQEAELWAVTLETLLKAMTQAECQIIVVGEETGWGVVPGYPLGRRFRDRMGELLRQIGAISDQ
VYLVSAGYALNLKALGIYVTPMVPLDGPKRD

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:
GO:0000166: Cobinamide kinase / cobinamide phosphate guanyltransferase
GO:0016301: Cobinamide kinase / cobinamide phosphate guanyltransferase
GO:0016310: Cobinamide kinase / cobinamide phosphate guanyltransferase
GO:0016740: Cobinamide kinase / cobinamide phosphate guanyltransferase
GO:0043752: Cobinamide kinase / cobinamide phosphate guanyltransferase
GO:0051188: Cobinamide kinase / cobinamide phosphate guanyltransferase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=33.1521739130435, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21283; Mature: 21283

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRHLVLVTGPARSGKSEWAENLAGQSNRSVIYVATAADYPEDEEWQTRIQAHQQRRPT
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCC
NWQTIHAPMDLAKTIQAQPKSICLLIDSLGTWLANILDQEAELWAVTLETLLKAMTQAEC
CCEEEECCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
QIIVVGEETGWGVVPGYPLGRRFRDRMGELLRQIGAISDQVYLVSAGYALNLKALGIYVT
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEEEE
PMVPLDGPKRD
EEECCCCCCCC
>Mature Secondary Structure
MDNRHLVLVTGPARSGKSEWAENLAGQSNRSVIYVATAADYPEDEEWQTRIQAHQQRRPT
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCC
NWQTIHAPMDLAKTIQAQPKSICLLIDSLGTWLANILDQEAELWAVTLETLLKAMTQAEC
CCEEEECCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
QIIVVGEETGWGVVPGYPLGRRFRDRMGELLRQIGAISDQVYLVSAGYALNLKALGIYVT
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEEEE
PMVPLDGPKRD
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]