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The map label for this gene is 158338723

Identifier: 158338723

GI number: 158338723

Start: 5691631

End: 5692815

Strand: Direct

Name: 158338723

Synonym: AM1_5631

Alternate gene names: NA

Gene position: 5691631-5692815 (Clockwise)

Preceding gene: 158338719

Following gene: 158338724

Centisome position: 87.51

GC content: 49.62

Gene sequence:

>1185_bases
ATGCGCGTAATCTTAATGACTGGCAAAGGTGGGGTTGGTAAGACCTCTGTTGCTGCTGCTACTGGACTCCGCTGTGCCGA
GCTGGGTTACAAGACCCTTGTTCTCAGTACCGATCCCGCCCATTCTTTAGCCGATAGCTTTGATATGGAGCTGGGCCATG
AAGCCCTGGAGGTTAAACCTAATTTGTGGGGGGCTGAGTTAGATGCCCTGCTTGAATTAGAAGGGAATTGGGGCGCGGTT
AAACGCTACATTACCCAGGTGCTGCAAGCCAGAGGACTTGAAGGGGTGCAGGCGGAAGAGCTAGCTATTCTCCCTGGCAT
GGATGAAATATTTAGCTTGGTGCGGATGAAGCGTCACTACGATGAGGGCACCTATGATGTCCTCGTGATTGACTCAGCAC
CGACCGGGACGGCTCTTCGTCTCCTGAGCTTGCCAGAAGTGGGCGGCTGGTATATGCGTCGGTTTTATAAGCCTTTCCAG
CGCATGTCTGTGACCCTCAGACCTCTGGTAGAGCCCTTCTTTAAGCCTATTGTCGGTTTCTCACTGCCTGATGAAGAAGT
GATGGATGCTCCCTATGAGTTTTACGAGCAGATTGAAGCCCTAGAGAAAGTATTAACAGACAATACCCAAACCTCCGTTC
GCCTGGTCACCAACCCAGAAAAGATGGTGATCAAAGAATCCTTAAGAGCCCATGCCTATTTGAGTCTGTACAATGTCTCC
ACAGATATGGTGGTGGCCAACCGGATTATTCCTGACCATGTCTCTGATCCGTTCTTTATGCATTGGAAACAGAACCAGAA
CCAATATCGCCAGGAAATCCACGATAACTTTCAACCCTTGCCTGTTAAAGAAGTGCCTCTCTTTCAGGAAGAAATGTGTG
GGTTAGAAGCCCTGGAGCGTTTGAAAGAAACCCTATATGACCAAGAAGATCCGACTCAGGTCTATCACAAGGAAACTACT
TTAAGGGTGATTCAGGAGCAGGGACAGTACAGCCTAGAAGTGTATCTCCCCGGAATCCCTAAGAACCAGGTGGAGTTGAG
TAAAACGGCGGATGAGCTGAATATCAGAATTGGTAATCACCGTCGTAATTTGGTTCTCCCCCAAGCGCTTGCTGCAATGC
AGCCTGCCGGGGCCAAGATGGAAGAGGACTACCTCAAAATTAAGTTTAGTGGGGCTGCGGCATAG

Upstream 100 bases:

>100_bases
CCCCACCTATTGAGTTAAATAGATTAGAGTAATGTAAAGAGAGGTTAAGCTGCTTAGCCCAATTTAGTGTGTTGATGCCC
AAAGCGATTGTAAGTAACCC

Downstream 100 bases:

>100_bases
CCCACCGATACATCGGCCCCCGCAATGTCATAAGATAGTTGAGCAGATTTTTTGGCTCAGAACCGTTCATGAATTCATTG
CAAGATAAGGTCGCAATCGT

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRVILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHEALEVKPNLWGAELDALLELEGNWGAV
KRYITQVLQARGLEGVQAEELAILPGMDEIFSLVRMKRHYDEGTYDVLVIDSAPTGTALRLLSLPEVGGWYMRRFYKPFQ
RMSVTLRPLVEPFFKPIVGFSLPDEEVMDAPYEFYEQIEALEKVLTDNTQTSVRLVTNPEKMVIKESLRAHAYLSLYNVS
TDMVVANRIIPDHVSDPFFMHWKQNQNQYRQEIHDNFQPLPVKEVPLFQEEMCGLEALERLKETLYDQEDPTQVYHKETT
LRVIQEQGQYSLEVYLPGIPKNQVELSKTADELNIRIGNHRRNLVLPQALAAMQPAGAKMEEDYLKIKFSGAAA

Sequences:

>Translated_394_residues
MRVILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHEALEVKPNLWGAELDALLELEGNWGAV
KRYITQVLQARGLEGVQAEELAILPGMDEIFSLVRMKRHYDEGTYDVLVIDSAPTGTALRLLSLPEVGGWYMRRFYKPFQ
RMSVTLRPLVEPFFKPIVGFSLPDEEVMDAPYEFYEQIEALEKVLTDNTQTSVRLVTNPEKMVIKESLRAHAYLSLYNVS
TDMVVANRIIPDHVSDPFFMHWKQNQNQYRQEIHDNFQPLPVKEVPLFQEEMCGLEALERLKETLYDQEDPTQVYHKETT
LRVIQEQGQYSLEVYLPGIPKNQVELSKTADELNIRIGNHRRNLVLPQALAAMQPAGAKMEEDYLKIKFSGAAA
>Mature_394_residues
MRVILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHEALEVKPNLWGAELDALLELEGNWGAV
KRYITQVLQARGLEGVQAEELAILPGMDEIFSLVRMKRHYDEGTYDVLVIDSAPTGTALRLLSLPEVGGWYMRRFYKPFQ
RMSVTLRPLVEPFFKPIVGFSLPDEEVMDAPYEFYEQIEALEKVLTDNTQTSVRLVTNPEKMVIKESLRAHAYLSLYNVS
TDMVVANRIIPDHVSDPFFMHWKQNQNQYRQEIHDNFQPLPVKEVPLFQEEMCGLEALERLKETLYDQEDPTQVYHKETT
LRVIQEQGQYSLEVYLPGIPKNQVELSKTADELNIRIGNHRRNLVLPQALAAMQPAGAKMEEDYLKIKFSGAAA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=298, Percent_Identity=22.8187919463087, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17557003, Length=295, Percent_Identity=24.0677966101695, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320103, Length=318, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586297, Length=304, Percent_Identity=22.6973684210526, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44605; Mature: 44605

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHEALEVKP
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHEEECC
NLWGAELDALLELEGNWGAVKRYITQVLQARGLEGVQAEELAILPGMDEIFSLVRMKRHY
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
DEGTYDVLVIDSAPTGTALRLLSLPEVGGWYMRRFYKPFQRMSVTLRPLVEPFFKPIVGF
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDEEVMDAPYEFYEQIEALEKVLTDNTQTSVRLVTNPEKMVIKESLRAHAYLSLYNVS
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEECC
TDMVVANRIIPDHVSDPFFMHWKQNQNQYRQEIHDNFQPLPVKEVPLFQEEMCGLEALER
CCHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LKETLYDQEDPTQVYHKETTLRVIQEQGQYSLEVYLPGIPKNQVELSKTADELNIRIGNH
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEHHHCCCCEEEEECCC
RRNLVLPQALAAMQPAGAKMEEDYLKIKFSGAAA
CCCEECHHHHHHCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRVILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHEALEVKP
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHEEECC
NLWGAELDALLELEGNWGAVKRYITQVLQARGLEGVQAEELAILPGMDEIFSLVRMKRHY
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
DEGTYDVLVIDSAPTGTALRLLSLPEVGGWYMRRFYKPFQRMSVTLRPLVEPFFKPIVGF
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDEEVMDAPYEFYEQIEALEKVLTDNTQTSVRLVTNPEKMVIKESLRAHAYLSLYNVS
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEECC
TDMVVANRIIPDHVSDPFFMHWKQNQNQYRQEIHDNFQPLPVKEVPLFQEEMCGLEALER
CCHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LKETLYDQEDPTQVYHKETTLRVIQEQGQYSLEVYLPGIPKNQVELSKTADELNIRIGNH
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEHHHCCCCEEEEECCC
RRNLVLPQALAAMQPAGAKMEEDYLKIKFSGAAA
CCCEECHHHHHHCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]