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The map label for this gene is arcB [C]

Identifier: 158338624

GI number: 158338624

Start: 5575534

End: 5577678

Strand: Reverse

Name: arcB [C]

Synonym: AM1_5528

Alternate gene names: 158338624

Gene position: 5577678-5575534 (Counterclockwise)

Preceding gene: 158338625

Following gene: 158338621

Centisome position: 85.76

GC content: 45.41

Gene sequence:

>2145_bases
GTGTTATTCGAACAAACCACTGTTGGTGAGTTTTTGCAGCAGACCTTAGTATGTCAAGCGGAAACTTCTATTCAAGACAT
ATTAGATAGACTTCAGCAGCAAGGTTCTGTATCTCCCGATGCTCTGTCTGAGGATGAGGCTAGTGATGGGGGCAATCTAT
CCCAATTAGTGGTGGTTAATGCACAGCAGCAACCTATTAGTCTTGTGCCTTTATCGCAATTTATCCATTTGTTTATTGCT
GAAAAACAGTCCGCCGAAGCGGTTTCGCCTCAGCAACCCATTGGAGAATGGGGCGATTTGCATAATCACCCCTTACAGCA
GGTGGCAGCTACAAGCTCTCTCAAGCAATTTTGGCAGTATTTACAAACCTTTTCCCAAGATCTCAGTTTGTCTTGGGCAA
TTGTTGAGGATGGAACCGGTAAATATTTGGGTTTATTGGATACCCCTAAGCTCGTTCAGTTCTTGGCCCATCATGCCCCC
TTGAGCGTTGCGATCAAGTTTTCTTCGGATCTAAAAAGTTCAGTCTCGCCAACTTTAGCGTTATCCGATACACCACTGGC
ATCACCAGAGTCATCAGATTCTCAAGACCCAATATCCACACCTGCTCCCTTGAGTGCGGAACTATTGGCTGAAATTAGCC
ATGAACTTAAATCTCCTTTGACGGCAATTCTCAGTTTGTCCAATGTTCTCAGTCATCAGGGCATTCAAAATTTATCGGAG
CGGCAATTGCAATATATGCAGTTGATTCATCAGAAAAGTCAGCATCTGATGGGGATCCTCAATACGCTGCTGGACTTAAC
TCAACTACCAGGCCAAGTTCAGCCTGAAACCCAGACAAATGTTCGCCTTGATCTGCTTTGTGACGATGCGATCGCACAAG
CGAAACGATACTATCAACTGGAAGAAGGCACAGCTAATCAGGCTTCTCTCATCATTCATCGGCATCCTCAGGGCGTCCTT
GGCTCCATCACCAGTGATGAGCTGAAATTACGTCAAATTCTGATACATCTTTTACACAATGCTTTAGGGGCAACTCAGGG
GCAGTCCCCCATCGCATTGAGAGTTGAGCAGTGGCAAGGGTGGACTATTTTTACCATTTCTGATCAGGGCGTTTCAATTC
CCCACCGACAACAACCCCTCATTTTTCAACTCCCCCAAGCTTGGACGATTCCTGACCAAGATTTTCTGGGTAAAACAGGA
CTAGGGTTGGTGCTGGCCCAACGCATAGCCGAACAGATGTCAGGGGATATTTCCTTTATCTCTGGGCCGACGCTGGGGAA
CACTTTCTCACTGTATGTGCCTCCAGAACCCCTGCGAAGACGGCAAACTAAAATTACTCAAAGCTTGGTTCTTCTGATTG
CCACAAACCCTAGTTTGATTGAACAAGTTAATCAATATTTATCGAAGCAATCTCTAAAGGTCGTCGTGGCCCGTTCAGAG
TTAGAAGCCGCTCAGAAAATCATCCTATTCAAACCTCAAGCCATTATTCTACAAACTCTGCTCACCACTGGCTCAGGATG
GGATATCCTTTCAATTCTCCAACAGCGAGAGAGGGATTGCCCCATCCTTTTAATAGGAAGTACCGCAGACTGTCAACAAA
TTACTGACTTTAGAGTGGATGGTTGCTTAACCTTAGACGAGCTGCAACCCGGCCTAGCACGATGGTTAGAGAAGTGCTTA
AAATCCAAGATTCCTACCCATGGATCGGCCCCTAAGCCGAAAAACCTCACACCATCCAACTTCCCAACAGCGCAAAAATT
AACCGTTCTCCATTTAGACAGCAATCAAGATCAATCCGGCAACGCATTACCCATTAATATCAGCCAATCCCTGTATAAAC
ATCAATGGAGAGTAATATCGACTACAACTTTGGATGAAGCTGAGTTATTGGTAGATATTTGGAAACCTGATGTTATTCTC
TATACCGATGATGATTCTGCGCCGTTCTTGAATATGGCAGCAGACTCTCCCTTAATCTCTTTCCCTTTTGTTATTCTTCA
TCCTGAGGTCCAGGAGATGGCCCTTGAGCGGGGAGACTTAGAGGTTTTTTCTCATGCTAACCTAACCCAACTGCCTTCCA
GCACTGAACTTTCAGAAGTATCGTCACTGTTACACATACTCAACAACTCTACCGCAGCAGAGTAG

Upstream 100 bases:

>100_bases
CTAAAATCTGCGATCTTCAACCAAAGTCCTTCTTTATATCTCTTTATCAGTATCGATATTGGCCAAACTTCCAAGCCGAT
CACGAATTAAGACGATTACT

Downstream 100 bases:

>100_bases
AGGACATACGATACTTTGAGGCTAGCTCCTGGGCTTACTGGAAGCTTTCTGGAGATTCAGAGGGAGGCGGTGTGGAAAAA
TCAGGCTGAGCAAAGGGATC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MLFEQTTVGEFLQQTLVCQAETSIQDILDRLQQQGSVSPDALSEDEASDGGNLSQLVVVNAQQQPISLVPLSQFIHLFIA
EKQSAEAVSPQQPIGEWGDLHNHPLQQVAATSSLKQFWQYLQTFSQDLSLSWAIVEDGTGKYLGLLDTPKLVQFLAHHAP
LSVAIKFSSDLKSSVSPTLALSDTPLASPESSDSQDPISTPAPLSAELLAEISHELKSPLTAILSLSNVLSHQGIQNLSE
RQLQYMQLIHQKSQHLMGILNTLLDLTQLPGQVQPETQTNVRLDLLCDDAIAQAKRYYQLEEGTANQASLIIHRHPQGVL
GSITSDELKLRQILIHLLHNALGATQGQSPIALRVEQWQGWTIFTISDQGVSIPHRQQPLIFQLPQAWTIPDQDFLGKTG
LGLVLAQRIAEQMSGDISFISGPTLGNTFSLYVPPEPLRRRQTKITQSLVLLIATNPSLIEQVNQYLSKQSLKVVVARSE
LEAAQKIILFKPQAIILQTLLTTGSGWDILSILQQRERDCPILLIGSTADCQQITDFRVDGCLTLDELQPGLARWLEKCL
KSKIPTHGSAPKPKNLTPSNFPTAQKLTVLHLDSNQDQSGNALPINISQSLYKHQWRVISTTTLDEAELLVDIWKPDVIL
YTDDDSAPFLNMAADSPLISFPFVILHPEVQEMALERGDLEVFSHANLTQLPSSTELSEVSSLLHILNNSTAAE

Sequences:

>Translated_714_residues
MLFEQTTVGEFLQQTLVCQAETSIQDILDRLQQQGSVSPDALSEDEASDGGNLSQLVVVNAQQQPISLVPLSQFIHLFIA
EKQSAEAVSPQQPIGEWGDLHNHPLQQVAATSSLKQFWQYLQTFSQDLSLSWAIVEDGTGKYLGLLDTPKLVQFLAHHAP
LSVAIKFSSDLKSSVSPTLALSDTPLASPESSDSQDPISTPAPLSAELLAEISHELKSPLTAILSLSNVLSHQGIQNLSE
RQLQYMQLIHQKSQHLMGILNTLLDLTQLPGQVQPETQTNVRLDLLCDDAIAQAKRYYQLEEGTANQASLIIHRHPQGVL
GSITSDELKLRQILIHLLHNALGATQGQSPIALRVEQWQGWTIFTISDQGVSIPHRQQPLIFQLPQAWTIPDQDFLGKTG
LGLVLAQRIAEQMSGDISFISGPTLGNTFSLYVPPEPLRRRQTKITQSLVLLIATNPSLIEQVNQYLSKQSLKVVVARSE
LEAAQKIILFKPQAIILQTLLTTGSGWDILSILQQRERDCPILLIGSTADCQQITDFRVDGCLTLDELQPGLARWLEKCL
KSKIPTHGSAPKPKNLTPSNFPTAQKLTVLHLDSNQDQSGNALPINISQSLYKHQWRVISTTTLDEAELLVDIWKPDVIL
YTDDDSAPFLNMAADSPLISFPFVILHPEVQEMALERGDLEVFSHANLTQLPSSTELSEVSSLLHILNNSTAAE
>Mature_714_residues
MLFEQTTVGEFLQQTLVCQAETSIQDILDRLQQQGSVSPDALSEDEASDGGNLSQLVVVNAQQQPISLVPLSQFIHLFIA
EKQSAEAVSPQQPIGEWGDLHNHPLQQVAATSSLKQFWQYLQTFSQDLSLSWAIVEDGTGKYLGLLDTPKLVQFLAHHAP
LSVAIKFSSDLKSSVSPTLALSDTPLASPESSDSQDPISTPAPLSAELLAEISHELKSPLTAILSLSNVLSHQGIQNLSE
RQLQYMQLIHQKSQHLMGILNTLLDLTQLPGQVQPETQTNVRLDLLCDDAIAQAKRYYQLEEGTANQASLIIHRHPQGVL
GSITSDELKLRQILIHLLHNALGATQGQSPIALRVEQWQGWTIFTISDQGVSIPHRQQPLIFQLPQAWTIPDQDFLGKTG
LGLVLAQRIAEQMSGDISFISGPTLGNTFSLYVPPEPLRRRQTKITQSLVLLIATNPSLIEQVNQYLSKQSLKVVVARSE
LEAAQKIILFKPQAIILQTLLTTGSGWDILSILQQRERDCPILLIGSTADCQQITDFRVDGCLTLDELQPGLARWLEKCL
KSKIPTHGSAPKPKNLTPSNFPTAQKLTVLHLDSNQDQSGNALPINISQSLYKHQWRVISTTTLDEAELLVDIWKPDVIL
YTDDDSAPFLNMAADSPLISFPFVILHPEVQEMALERGDLEVFSHANLTQLPSSTELSEVSSLLHILNNSTAAE

Specific function: Member Of The Two-Component Regulatory System Arcb/Arca. Sensor-Regulator Protein For Anaerobic Repression Of The Arc Modulon. Activates Arca Via A Four-Step Phosphorelay. Arcb Can Also Dephosphorylate Arca By A Reverse Phosphorelay Involving His- 717 And

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=358, Percent_Identity=27.9329608938547, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=28.8702928870293, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=24.5674740484429, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=28.1512605042017, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78680; Mature: 78680

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFEQTTVGEFLQQTLVCQAETSIQDILDRLQQQGSVSPDALSEDEASDGGNLSQLVVVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEE
AQQQPISLVPLSQFIHLFIAEKQSAEAVSPQQPIGEWGDLHNHPLQQVAATSSLKQFWQY
CCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQTFSQDLSLSWAIVEDGTGKYLGLLDTPKLVQFLAHHAPLSVAIKFSSDLKSSVSPTLA
HHHHHHCCCEEEEEEECCCCCEEECCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCEEE
LSDTPLASPESSDSQDPISTPAPLSAELLAEISHELKSPLTAILSLSNVLSHQGIQNLSE
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLQYMQLIHQKSQHLMGILNTLLDLTQLPGQVQPETQTNVRLDLLCDDAIAQAKRYYQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHEEC
EEGTANQASLIIHRHPQGVLGSITSDELKLRQILIHLLHNALGATQGQSPIALRVEQWQG
CCCCCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
WTIFTISDQGVSIPHRQQPLIFQLPQAWTIPDQDFLGKTGLGLVLAQRIAEQMSGDISFI
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEE
SGPTLGNTFSLYVPPEPLRRRQTKITQSLVLLIATNPSLIEQVNQYLSKQSLKVVVARSE
CCCCCCCEEEEEECCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCEEEEEEHHH
LEAAQKIILFKPQAIILQTLLTTGSGWDILSILQQRERDCPILLIGSTADCQQITDFRVD
HHHHHHEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCC
GCLTLDELQPGLARWLEKCLKSKIPTHGSAPKPKNLTPSNFPTAQKLTVLHLDSNQDQSG
CEEEHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
NALPINISQSLYKHQWRVISTTTLDEAELLVDIWKPDVILYTDDDSAPFLNMAADSPLIS
CEEEEEHHHHHHHCCCEEEEECCCCHHHHHHEECCCCEEEEECCCCCCEEEECCCCCCCC
FPFVILHPEVQEMALERGDLEVFSHANLTQLPSSTELSEVSSLLHILNNSTAAE
CCEEEECCCHHHHHHHCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLFEQTTVGEFLQQTLVCQAETSIQDILDRLQQQGSVSPDALSEDEASDGGNLSQLVVVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEE
AQQQPISLVPLSQFIHLFIAEKQSAEAVSPQQPIGEWGDLHNHPLQQVAATSSLKQFWQY
CCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQTFSQDLSLSWAIVEDGTGKYLGLLDTPKLVQFLAHHAPLSVAIKFSSDLKSSVSPTLA
HHHHHHCCCEEEEEEECCCCCEEECCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCEEE
LSDTPLASPESSDSQDPISTPAPLSAELLAEISHELKSPLTAILSLSNVLSHQGIQNLSE
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLQYMQLIHQKSQHLMGILNTLLDLTQLPGQVQPETQTNVRLDLLCDDAIAQAKRYYQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHEEC
EEGTANQASLIIHRHPQGVLGSITSDELKLRQILIHLLHNALGATQGQSPIALRVEQWQG
CCCCCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
WTIFTISDQGVSIPHRQQPLIFQLPQAWTIPDQDFLGKTGLGLVLAQRIAEQMSGDISFI
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEE
SGPTLGNTFSLYVPPEPLRRRQTKITQSLVLLIATNPSLIEQVNQYLSKQSLKVVVARSE
CCCCCCCEEEEEECCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCEEEEEEHHH
LEAAQKIILFKPQAIILQTLLTTGSGWDILSILQQRERDCPILLIGSTADCQQITDFRVD
HHHHHHEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCC
GCLTLDELQPGLARWLEKCLKSKIPTHGSAPKPKNLTPSNFPTAQKLTVLHLDSNQDQSG
CEEEHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
NALPINISQSLYKHQWRVISTTTLDEAELLVDIWKPDVILYTDDDSAPFLNMAADSPLIS
CEEEEEHHHHHHHCCCEEEEECCCCHHHHHHEECCCCEEEEECCCCCCEEEECCCCCCCC
FPFVILHPEVQEMALERGDLEVFSHANLTQLPSSTELSEVSSLLHILNNSTAAE
CCEEEECCCHHHHHHHCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]