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The map label for this gene is pip [H]

Identifier: 158338621

GI number: 158338621

Start: 5571715

End: 5572665

Strand: Reverse

Name: pip [H]

Synonym: AM1_5525

Alternate gene names: 158338621

Gene position: 5572665-5571715 (Counterclockwise)

Preceding gene: 158338624

Following gene: 158338620

Centisome position: 85.68

GC content: 49.0

Gene sequence:

>951_bases
ATGCGTGACCTTTACCCAGTTATCACTCCTTATACAACGGGAAAACTTCAGGTTTCTGAGCTGCATACCCTTTATTACGA
AGAAGTGGGAAATCCCCAGGGGAAACCGGCTGTATTTCTGCATGGCGGGCCAGGGGGCGGCATCGATCCGGTCTATCGGC
AATATTTTGATCCGCAGCAATGGCGATTGGTGCTGTTCGATCAGCGGGGTTGTGGGCAAAGTACCCCCCATGCAGAGTTA
AGAGAAAACACCACCTGGAATTTAGTTAGGGATATTGAAGCCCTGCGTCAGCATTTAAGTATCGATCAATGGGTGGTCTT
TGGTGGGAGTTGGGGTAGTACTTTGGCGCTGGCCTATAGCCAAACCCATCCTGAAGCCTGCAAGGGATTAATCTTGCGGG
GCATATTTATGTTGCGCAATCAAGAGCTGCAGTGGTTTTACCAAGAAGGGACCAGCAATATTTTCCCAGATGCCTGGGAA
GCTTATCTCCAGACCATCCCTCCAGAAGAGCGCCATGATTTAATCAACGCTTATTATCGCCGCCTCACCAGCAATGATCC
AGCGATTCAATTAGAAGCCGCCAAAGCCTGGTCTGTTTGGGAAGCGACAACCAGCAAACTAATCCCCGATCTTGAATTAC
AAGAAAAATGTGGTGAAGACACCTTTGCCACGGCATTTGCACGCATTGAATGTCACTATTTTGTCAACAAGGGCTTTTTA
GATACTGAGGATCAGCTGTTACGGGGGTGCGATCACATCCAGCATCTCCCCATTGTCATTGTCCAAGGCCGATACGATGT
GGTGTGTCCCGTTATCTCCGCCTGGGAACTCCACCAACAACTACCCCAATCCGAATTACAAATCATCCCTGATGCCGGCC
ATTCCATTACAGAACCTGGCATTCGCAATGCTTTGATAGAAGCAACCGACCGCTTTGCCCAAATTCCATAA

Upstream 100 bases:

>100_bases
GGGTTACCTGTGATTGAACATTACAAAACGGTGAAATCAGAGGTCTTGAGCGGTGAGACCATTTATCTTGAAGAGCAAGA
GATAGCCGTTGAATTCCAAA

Downstream 100 bases:

>100_bases
CATGCCTTGGCTAAGACTTAATTTATGGTCTAGCAAGAAAACAAGATCGATGCTTTCAGAAGGGCGGTTTCAGATTACTA
TGGAAGGAATGGCTGAAACC

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRDLYPVITPYTTGKLQVSELHTLYYEEVGNPQGKPAVFLHGGPGGGIDPVYRQYFDPQQWRLVLFDQRGCGQSTPHAEL
RENTTWNLVRDIEALRQHLSIDQWVVFGGSWGSTLALAYSQTHPEACKGLILRGIFMLRNQELQWFYQEGTSNIFPDAWE
AYLQTIPPEERHDLINAYYRRLTSNDPAIQLEAAKAWSVWEATTSKLIPDLELQEKCGEDTFATAFARIECHYFVNKGFL
DTEDQLLRGCDHIQHLPIVIVQGRYDVVCPVISAWELHQQLPQSELQIIPDAGHSITEPGIRNALIEATDRFAQIP

Sequences:

>Translated_316_residues
MRDLYPVITPYTTGKLQVSELHTLYYEEVGNPQGKPAVFLHGGPGGGIDPVYRQYFDPQQWRLVLFDQRGCGQSTPHAEL
RENTTWNLVRDIEALRQHLSIDQWVVFGGSWGSTLALAYSQTHPEACKGLILRGIFMLRNQELQWFYQEGTSNIFPDAWE
AYLQTIPPEERHDLINAYYRRLTSNDPAIQLEAAKAWSVWEATTSKLIPDLELQEKCGEDTFATAFARIECHYFVNKGFL
DTEDQLLRGCDHIQHLPIVIVQGRYDVVCPVISAWELHQQLPQSELQIIPDAGHSITEPGIRNALIEATDRFAQIP
>Mature_316_residues
MRDLYPVITPYTTGKLQVSELHTLYYEEVGNPQGKPAVFLHGGPGGGIDPVYRQYFDPQQWRLVLFDQRGCGQSTPHAEL
RENTTWNLVRDIEALRQHLSIDQWVVFGGSWGSTLALAYSQTHPEACKGLILRGIFMLRNQELQWFYQEGTSNIFPDAWE
AYLQTIPPEERHDLINAYYRRLTSNDPAIQLEAAKAWSVWEATTSKLIPDLELQEKCGEDTFATAFARIECHYFVNKGFL
DTEDQLLRGCDHIQHLPIVIVQGRYDVVCPVISAWELHQQLPQSELQIIPDAGHSITEPGIRNALIEATDRFAQIP

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:
GO:0004177: Proline iminopeptidase
GO:0005737: Proline iminopeptidase
GO:0006508: Proline iminopeptidase
GO:0008233: Proline iminopeptidase
GO:0016787: Proline iminopeptidase

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36063; Mature: 36063

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLYPVITPYTTGKLQVSELHTLYYEEVGNPQGKPAVFLHGGPGGGIDPVYRQYFDPQQ
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCCCC
WRLVLFDQRGCGQSTPHAELRENTTWNLVRDIEALRQHLSIDQWVVFGGSWGSTLALAYS
EEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEC
QTHPEACKGLILRGIFMLRNQELQWFYQEGTSNIFPDAWEAYLQTIPPEERHDLINAYYR
CCCHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
RLTSNDPAIQLEAAKAWSVWEATTSKLIPDLELQEKCGEDTFATAFARIECHYFVNKGFL
HHCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHEEEEEEECCCCC
DTEDQLLRGCDHIQHLPIVIVQGRYDVVCPVISAWELHQQLPQSELQIIPDAGHSITEPG
CCHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
IRNALIEATDRFAQIP
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDLYPVITPYTTGKLQVSELHTLYYEEVGNPQGKPAVFLHGGPGGGIDPVYRQYFDPQQ
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCCCC
WRLVLFDQRGCGQSTPHAELRENTTWNLVRDIEALRQHLSIDQWVVFGGSWGSTLALAYS
EEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEC
QTHPEACKGLILRGIFMLRNQELQWFYQEGTSNIFPDAWEAYLQTIPPEERHDLINAYYR
CCCHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
RLTSNDPAIQLEAAKAWSVWEATTSKLIPDLELQEKCGEDTFATAFARIECHYFVNKGFL
HHCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHEEEEEEECCCCC
DTEDQLLRGCDHIQHLPIVIVQGRYDVVCPVISAWELHQQLPQSELQIIPDAGHSITEPG
CCHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
IRNALIEATDRFAQIP
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA