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The map label for this gene is yybE [H]

Identifier: 158338435

GI number: 158338435

Start: 5398031

End: 5398906

Strand: Reverse

Name: yybE [H]

Synonym: AM1_5334

Alternate gene names: 158338435

Gene position: 5398906-5398031 (Counterclockwise)

Preceding gene: 158338438

Following gene: 158338433

Centisome position: 83.01

GC content: 51.94

Gene sequence:

>876_bases
ATGGATCTCTACCAAGTTCGATATTTTCTGACCATTGCTGAAACGGGTACCTTTTCGCGGGCGGCAGAGCGACTTTATCT
TTCTCAGCCGTCTCTATCAGCAGGAATTAAAAAGCTAGAGCAGGAGCTAGGGGTGGCTTTGTTCGAGCGGGGTGGACGGC
GGACGGTTCTAACCGCAGCGGGACAGGCCTTTAAGGAGCGGGCCACGGTGATTATGGCTCAGTACCAAGCGGCTCTCCAC
GAACTTAAAGGCTTTAATGATCGACCGACGCTGAAGGTAGGGGTGCTAAGCACCTTGCGGGTGAGTGAGCTGGCCGATTT
GGTCCATAGTTTTCAGCAACACTATTCCCACGTGACCCTGGAACTGTATGACCATCCTGCCGATGCGTTACAAGACAAAC
TTACCCAGGGTGAAATTGATGTGGCGATTACGGTGTTGGGACCACAGGATGATGCTCAAACCTCAACCCTTTTGTTTGCT
CAACCTTTACTGCTCGCCGTTCCTGCCCGTCATCCCTTGGCGCAGCGAACTTCCGTGCGGTTGGCTGAACTAGATGGTCA
ACCCTATATTGATCGGGTGAACTGTGAATTCTTTAAGCAAGAGTGTCAACTGCTAGAGGCGAAAAAAATCTGTCCCCAAG
TCGTGTATCGAGCCAGCCATGAGGAATGGGTGATTTCCTTGGTCAAAGCTGGACTGGGGTTGAGTGTGATGCCCTTTTGG
CGGGGACTGACGGATATTGTTTATCTGCCGGTGGTCGATATTGACTTTCAGCGTCGGGTTGGGATTAAGTGGCGGCTTCA
GTGTTCCGAGATGGTGGAGCAGTTTTGTCGATTTGCTACGAGCCATAATTGGGAGTCGATGGCGGGGGGAGACTAA

Upstream 100 bases:

>100_bases
GGGTGCGATCGCAGTTACGATTCACACTTTCTATCCTGGAGTAGGCTAATCTATAGAGCAAGACTATTTTTATTATTGAA
ACTATAGATATTGACTATAT

Downstream 100 bases:

>100_bases
GGTGCGATCGCAACCAACGCATCCCAAAATGCCTGCAGATCTTCATAGTGGGGGAGTACCACTGGTGCCCCTTCGGCTTT
AAGCCGTTGGGCATCTTCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDLYQVRYFLTIAETGTFSRAAERLYLSQPSLSAGIKKLEQELGVALFERGGRRTVLTAAGQAFKERATVIMAQYQAALH
ELKGFNDRPTLKVGVLSTLRVSELADLVHSFQQHYSHVTLELYDHPADALQDKLTQGEIDVAITVLGPQDDAQTSTLLFA
QPLLLAVPARHPLAQRTSVRLAELDGQPYIDRVNCEFFKQECQLLEAKKICPQVVYRASHEEWVISLVKAGLGLSVMPFW
RGLTDIVYLPVVDIDFQRRVGIKWRLQCSEMVEQFCRFATSHNWESMAGGD

Sequences:

>Translated_291_residues
MDLYQVRYFLTIAETGTFSRAAERLYLSQPSLSAGIKKLEQELGVALFERGGRRTVLTAAGQAFKERATVIMAQYQAALH
ELKGFNDRPTLKVGVLSTLRVSELADLVHSFQQHYSHVTLELYDHPADALQDKLTQGEIDVAITVLGPQDDAQTSTLLFA
QPLLLAVPARHPLAQRTSVRLAELDGQPYIDRVNCEFFKQECQLLEAKKICPQVVYRASHEEWVISLVKAGLGLSVMPFW
RGLTDIVYLPVVDIDFQRRVGIKWRLQCSEMVEQFCRFATSHNWESMAGGD
>Mature_291_residues
MDLYQVRYFLTIAETGTFSRAAERLYLSQPSLSAGIKKLEQELGVALFERGGRRTVLTAAGQAFKERATVIMAQYQAALH
ELKGFNDRPTLKVGVLSTLRVSELADLVHSFQQHYSHVTLELYDHPADALQDKLTQGEIDVAITVLGPQDDAQTSTLLFA
QPLLLAVPARHPLAQRTSVRLAELDGQPYIDRVNCEFFKQECQLLEAKKICPQVVYRASHEEWVISLVKAGLGLSVMPFW
RGLTDIVYLPVVDIDFQRRVGIKWRLQCSEMVEQFCRFATSHNWESMAGGD

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=30.5882352941176, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=27.9569892473118, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=31.7391304347826, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=28.2786885245902, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87081904, Length=181, Percent_Identity=34.8066298342541, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787601, Length=263, Percent_Identity=26.2357414448669, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=27.1604938271605, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787806, Length=240, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787530, Length=274, Percent_Identity=24.8175182481752, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI48994962, Length=229, Percent_Identity=28.3842794759825, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789639, Length=251, Percent_Identity=26.2948207171315, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=31.0126582278481, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786713, Length=184, Percent_Identity=33.1521739130435, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=27.1255060728745, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082132, Length=282, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082024, Length=169, Percent_Identity=31.3609467455621, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789204, Length=241, Percent_Identity=24.0663900414938, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=141, Percent_Identity=31.9148936170213, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787949, Length=142, Percent_Identity=26.7605633802817, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32783; Mature: 32783

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYQVRYFLTIAETGTFSRAAERLYLSQPSLSAGIKKLEQELGVALFERGGRRTVLTAA
CCCEEEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
GQAFKERATVIMAQYQAALHELKGFNDRPTLKVGVLSTLRVSELADLVHSFQQHYSHVTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCEEEE
ELYDHPADALQDKLTQGEIDVAITVLGPQDDAQTSTLLFAQPLLLAVPARHPLAQRTSVR
EEECCCHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCE
LAELDGQPYIDRVNCEFFKQECQLLEAKKICPQVVYRASHEEWVISLVKAGLGLSVMPFW
EEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
RGLTDIVYLPVVDIDFQRRVGIKWRLQCSEMVEQFCRFATSHNWESMAGGD
CCHHHEEEEEEECCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDLYQVRYFLTIAETGTFSRAAERLYLSQPSLSAGIKKLEQELGVALFERGGRRTVLTAA
CCCEEEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
GQAFKERATVIMAQYQAALHELKGFNDRPTLKVGVLSTLRVSELADLVHSFQQHYSHVTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCEEEE
ELYDHPADALQDKLTQGEIDVAITVLGPQDDAQTSTLLFAQPLLLAVPARHPLAQRTSVR
EEECCCHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCE
LAELDGQPYIDRVNCEFFKQECQLLEAKKICPQVVYRASHEEWVISLVKAGLGLSVMPFW
EEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
RGLTDIVYLPVVDIDFQRRVGIKWRLQCSEMVEQFCRFATSHNWESMAGGD
CCHHHEEEEEEECCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]