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The map label for this gene is ureC [H]

Identifier: 158338215

GI number: 158338215

Start: 5171530

End: 5173227

Strand: Direct

Name: ureC [H]

Synonym: AM1_5109

Alternate gene names: 158338215

Gene position: 5171530-5173227 (Clockwise)

Preceding gene: 158338214

Following gene: 158338216

Centisome position: 79.52

GC content: 52.77

Gene sequence:

>1698_bases
ATGGACCGCCGCGCCTATGCGGAAACCTATGGCCCTACGGTGGGCGATCGCATTCGCCTGGCTGATACTGAGCTGATTAT
CGAAGTGGAGCAAGACCACACCACCTACGGAGATGAGGTCAAGTTTGGTGGCGGTAAAGTGATTCGCGATGGCATGGGCC
AGTCGCCGATTACCAATGCCGATGGCGCCGTGGATACTGTGATTACCAACGCCCTTATCTTGGACTGGTGGGGCATCGTC
AAAGCGGATATCGGTATTAAGGACGGTAAGATTGCTGCCATTGGCAAGGCGGGTAACCCCTATATCCAAGACAAGATTGA
TATTGTGATCGGCCCAGGTACAGAGGCAATCGCGGGGGAGGGGATGATTCTGACGGCGGGAGGGATTGACTCCCACATCC
ACTTTATTTGTCCCCAGCAAATTGAAGTTGCGATCGCATCCGGTGTCACAACCATGCTTGGCGGCGGCACAGGTCCTGCG
GCAGGCACCAACGCCACCACCTGCACTCCTGGCCCTTGGAATATCTATCGGATGCTGCAATCTGCCGATGCCTTTCCTAT
GAACTTAGGCTTTTTAGGCAAAGGCAACTCCAGCCAGCCCGCCGCTTTAGTCGAACAAGTTAAAGCCGGAGCGATGGGCC
TGAAGCTTCATGAAGACTGGGGCACGACTCCTGCTGCCATTGATACCTGCTTGAGCGTTGCCGACGAGTTTGATGTCCAG
GTGGCGATTCACACGGATACCCTGAATGAAGCGGGCTTTGTCGAAAATACCATTTCAGCTTTCAAAAACCGCGTCATTCA
CACCTATCACACGGAAGGGGCCGGGGGTGGCCACGCCCCGGATATTATCAAGGTTTGTGGAGAAGCCAATGTCCTACCGT
CCTCCACCAACCCTACCCGGCCCTACACCGTCAATACCCTAGATGAACACTTGGATATGCTCATGGTGTGTCATCACCTC
GATGCAGGCATTCCTGAAGATGTGGCCTTTGCTGAATCCAGAATTCGCCGAGAAACCATCGCTGCTGAAGATATCCTCCA
TGACTTGGGGGCGTTTAGTATGATTGCCTCGGATTCCCAGGCTATGGGCCGTGTAGGTGAGGTGATTATTCGTACCTGGC
AGACGGGCCACAAAATGAAGGTACAGCGGGGACCGCTTTCAGAAGACTCAGATCGCAATGATAATCATCGAGCGAAGCGT
TACGTCGCCAAGTACACGATTAATCCAGCTATTACCCACGGGATTGCCGACCATGTGGGTTCGGTGGAAGTGGGCAAGCT
AGCCGATCTTTGTTTGTGGAAGCCAGCTTTGTTTGGCGTCAAGCCAGAAATGGTGATTAAAGGTGGCTTTATTGCCTGGT
CCCAAATGGGAGATGCCAATGCCAGTATTCCCACGCCCCAACCGGTGCATATGCGACCGATGTTTGGGGGATTTGGAGGT
GTGATCGCAGCGACGTCTCTTACGTTTGTCTCTCAAGCCGCTATGGAGATGGGGATTCCTGGCCAAATTGGTTTGCAGAA
AAACGTCGTTGCCATTTCCAATACGCGCAATCTTAGCAAGGCGGATATGAAGTTAAATGATGCTTTGCCAAAAATTGAGG
TGGATTCTGAGACTTATGAGGTGAGGGCCGATGGAGAATTGCTTACCTGTGAGCCTGCAACAGTGTTGCCCATGGCACAG
CGGTACTTTTTGTTTTGA

Upstream 100 bases:

>100_bases
TCCAATATCGAGTTTTGTAAAGGTTACAGCGATCAAACGTTACCGTTCGATTTAGAATTTACTGGATCAGTCTTCATAAA
GGGCAGCTATGGCATATCGA

Downstream 100 bases:

>100_bases
AAGGCCAATCCATTGGAGTGAAAGGTGAACTAGATATATCGACGCTTTTATGGTTTTGGCTGTAACCCTCATATTGACAG
AATTGAAGATTTTTTAATAA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MDRRAYAETYGPTVGDRIRLADTELIIEVEQDHTTYGDEVKFGGGKVIRDGMGQSPITNADGAVDTVITNALILDWWGIV
KADIGIKDGKIAAIGKAGNPYIQDKIDIVIGPGTEAIAGEGMILTAGGIDSHIHFICPQQIEVAIASGVTTMLGGGTGPA
AGTNATTCTPGPWNIYRMLQSADAFPMNLGFLGKGNSSQPAALVEQVKAGAMGLKLHEDWGTTPAAIDTCLSVADEFDVQ
VAIHTDTLNEAGFVENTISAFKNRVIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHL
DAGIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTGHKMKVQRGPLSEDSDRNDNHRAKR
YVAKYTINPAITHGIADHVGSVEVGKLADLCLWKPALFGVKPEMVIKGGFIAWSQMGDANASIPTPQPVHMRPMFGGFGG
VIAATSLTFVSQAAMEMGIPGQIGLQKNVVAISNTRNLSKADMKLNDALPKIEVDSETYEVRADGELLTCEPATVLPMAQ
RYFLF

Sequences:

>Translated_565_residues
MDRRAYAETYGPTVGDRIRLADTELIIEVEQDHTTYGDEVKFGGGKVIRDGMGQSPITNADGAVDTVITNALILDWWGIV
KADIGIKDGKIAAIGKAGNPYIQDKIDIVIGPGTEAIAGEGMILTAGGIDSHIHFICPQQIEVAIASGVTTMLGGGTGPA
AGTNATTCTPGPWNIYRMLQSADAFPMNLGFLGKGNSSQPAALVEQVKAGAMGLKLHEDWGTTPAAIDTCLSVADEFDVQ
VAIHTDTLNEAGFVENTISAFKNRVIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHL
DAGIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTGHKMKVQRGPLSEDSDRNDNHRAKR
YVAKYTINPAITHGIADHVGSVEVGKLADLCLWKPALFGVKPEMVIKGGFIAWSQMGDANASIPTPQPVHMRPMFGGFGG
VIAATSLTFVSQAAMEMGIPGQIGLQKNVVAISNTRNLSKADMKLNDALPKIEVDSETYEVRADGELLTCEPATVLPMAQ
RYFLF
>Mature_565_residues
MDRRAYAETYGPTVGDRIRLADTELIIEVEQDHTTYGDEVKFGGGKVIRDGMGQSPITNADGAVDTVITNALILDWWGIV
KADIGIKDGKIAAIGKAGNPYIQDKIDIVIGPGTEAIAGEGMILTAGGIDSHIHFICPQQIEVAIASGVTTMLGGGTGPA
AGTNATTCTPGPWNIYRMLQSADAFPMNLGFLGKGNSSQPAALVEQVKAGAMGLKLHEDWGTTPAAIDTCLSVADEFDVQ
VAIHTDTLNEAGFVENTISAFKNRVIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHL
DAGIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTGHKMKVQRGPLSEDSDRNDNHRAKR
YVAKYTINPAITHGIADHVGSVEVGKLADLCLWKPALFGVKPEMVIKGGFIAWSQMGDANASIPTPQPVHMRPMFGGFGG
VIAATSLTFVSQAAMEMGIPGQIGLQKNVVAISNTRNLSKADMKLNDALPKIEVDSETYEVRADGELLTCEPATVLPMAQ
RYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:
GO:0005737: Urease subunit alpha
GO:0006807: Urease subunit alpha
GO:0009039: Urease subunit alpha
GO:0016151: Urease subunit alpha
GO:0016787: Urease subunit alpha
GO:0016810: Urease subunit alpha
GO:0019627: Urease subunit alpha
GO:0046872: Urease subunit alpha

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60355; Mature: 60355

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRAYAETYGPTVGDRIRLADTELIIEVEQDHTTYGDEVKFGGGKVIRDGMGQSPITNA
CCCCCCHHHCCCCCCCEEEEECEEEEEEECCCCCCCCCEEEECCCEEEECCCCCCCCCCC
DGAVDTVITNALILDWWGIVKADIGIKDGKIAAIGKAGNPYIQDKIDIVIGPGTEAIAGE
CCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHCCC
GMILTAGGIDSHIHFICPQQIEVAIASGVTTMLGGGTGPAAGTNATTCTPGPWNIYRMLQ
CEEEEECCCCCCEEEECCCHHEEEHHCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
SADAFPMNLGFLGKGNSSQPAALVEQVKAGAMGLKLHEDWGTTPAAIDTCLSVADEFDVQ
CCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEE
VAIHTDTLNEAGFVENTISAFKNRVIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTR
EEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
PYTVNTLDEHLDMLMVCHHLDAGIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQ
CEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AMGRVGEVIIRTWQTGHKMKVQRGPLSEDSDRNDNHRAKRYVAKYTINPAITHGIADHVG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHEEEEEECCHHHHHHHHHHCC
SVEVGKLADLCLWKPALFGVKPEMVIKGGFIAWSQMGDANASIPTPQPVHMRPMFGGFGG
CEEHHHHHHHHHCCHHHHCCCCCEEEECCEEEEECCCCCCCCCCCCCCEEECCCCCCCCH
VIAATSLTFVSQAAMEMGIPGQIGLQKNVVAISNTRNLSKADMKLNDALPKIEVDSETYE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHCCCHHCCCCCEEECCCEEE
VRADGELLTCEPATVLPMAQRYFLF
EEECCCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MDRRAYAETYGPTVGDRIRLADTELIIEVEQDHTTYGDEVKFGGGKVIRDGMGQSPITNA
CCCCCCHHHCCCCCCCEEEEECEEEEEEECCCCCCCCCEEEECCCEEEECCCCCCCCCCC
DGAVDTVITNALILDWWGIVKADIGIKDGKIAAIGKAGNPYIQDKIDIVIGPGTEAIAGE
CCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHCCC
GMILTAGGIDSHIHFICPQQIEVAIASGVTTMLGGGTGPAAGTNATTCTPGPWNIYRMLQ
CEEEEECCCCCCEEEECCCHHEEEHHCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
SADAFPMNLGFLGKGNSSQPAALVEQVKAGAMGLKLHEDWGTTPAAIDTCLSVADEFDVQ
CCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEE
VAIHTDTLNEAGFVENTISAFKNRVIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTR
EEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
PYTVNTLDEHLDMLMVCHHLDAGIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQ
CEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AMGRVGEVIIRTWQTGHKMKVQRGPLSEDSDRNDNHRAKRYVAKYTINPAITHGIADHVG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHEEEEEECCHHHHHHHHHHCC
SVEVGKLADLCLWKPALFGVKPEMVIKGGFIAWSQMGDANASIPTPQPVHMRPMFGGFGG
CEEHHHHHHHHHCCHHHHCCCCCEEEECCEEEEECCCCCCCCCCCCCCEEECCCCCCCCH
VIAATSLTFVSQAAMEMGIPGQIGLQKNVVAISNTRNLSKADMKLNDALPKIEVDSETYE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHCCCHHCCCCCEEECCCEEE
VRADGELLTCEPATVLPMAQRYFLF
EEECCCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA