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The map label for this gene is yjgB [H]

Identifier: 158337931

GI number: 158337931

Start: 4853101

End: 4854099

Strand: Direct

Name: yjgB [H]

Synonym: AM1_4818

Alternate gene names: 158337931

Gene position: 4853101-4854099 (Clockwise)

Preceding gene: 158337929

Following gene: 158337932

Centisome position: 74.62

GC content: 52.65

Gene sequence:

>999_bases
ATGGTCAACGCCTATGCGGCCTTTGAACAGGGGGGAGTCCTTCAGCCCTTTGAGTATGATCCTGGACCGTTAGGTCGCCA
ACAGGTGGATATCCAAGTTGAGTATTGTGGTATCTGCCACAGCGACCTCAGCATGATTAAAAACGAATGGGGGATGACCC
AGTATCCCTTTGTACCTGGCCATGAAATTGTCGGTATTGTGGCTGAGATCGGCTCTGAGGTGACGACCCTGCGGGTGGGC
CAGCGCGTCGGATTGGGGTGGTATTCGTCCTCCTGTATGCATTGCGAGTGGTGCATGGGGGGCGATCACCATCTCTGTCT
ATCTGCTGAAGGCACTATTGTGGGCCGACCCGGTGGATTTGCCGATCAGGTTCGGGCCGATCAGAGTTGGATTGTACCCA
TTCCAGAGTCCATTGATTCGGCGGTTGCAGGTCCCCTCTTCTGTGCCGGCATTACAGTATTTCAGCCAATCATTCAATGT
GGCGTCCAACCCACGGATCGAGTGGCCGTGATTGGTATTGGTGGACTCGGCCATTTAGCCCTACAGTTTCTCAATGCCTG
GGGATGTGAAGTGACGGCGTTATCCACCCAACCTGACAAGGAAGCTGAAGCCCGCAGATTAGGCGCTCACCATTTTGTCA
ATACTCGCGATCCAGCAGCATTGCAGGCAATCGCTAATTCCTGTGATTACATTATTTCCACCGTCAATGTGTCTTTAGAG
TGGTCCATCTATCTCAATGCGCTTCGGCCTAAAGGTCGACTGCATTTGGTTGGGGTGGCTCCTGATCTGTCTTTACCTGT
CTTTCCCTTATTGGCGGGACAGCGATCCATCTCAGGCAGCCCTGTAGGGAGTCCAGCCACCATCACTAAAATGCTGAACT
TTGTAGCTCGCCATGGGCTTGCACCTCAGACTGAGGTTTTTCCTCTCGCTCAAGTCAATGAAGCGTTAGAGAAGTTACGC
AGTCAGCACCCTCCCTATCGTTTGGCCCTGAAATGCTAA

Upstream 100 bases:

>100_bases
CAGGATTTGAATTTCGCCAATTCTTAAAACAGTCCACAGGCCAAGTGTGGTGAGATTTTTTAGATTATTATCACCCCATC
TGCTTCATGAGGATGAATGA

Downstream 100 bases:

>100_bases
GTTCTAACGATTCCGCTCCAACCCCTAAGCTGTTAATAACGGGTGCCAGTGGCTTTTTGGGGTGGTATCTCTGCCAGGTT
GCCCAATCCAGCTGGCAGGT

Product: Zinc-containing alcohol dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVNAYAAFEQGGVLQPFEYDPGPLGRQQVDIQVEYCGICHSDLSMIKNEWGMTQYPFVPGHEIVGIVAEIGSEVTTLRVG
QRVGLGWYSSSCMHCEWCMGGDHHLCLSAEGTIVGRPGGFADQVRADQSWIVPIPESIDSAVAGPLFCAGITVFQPIIQC
GVQPTDRVAVIGIGGLGHLALQFLNAWGCEVTALSTQPDKEAEARRLGAHHFVNTRDPAALQAIANSCDYIISTVNVSLE
WSIYLNALRPKGRLHLVGVAPDLSLPVFPLLAGQRSISGSPVGSPATITKMLNFVARHGLAPQTEVFPLAQVNEALEKLR
SQHPPYRLALKC

Sequences:

>Translated_332_residues
MVNAYAAFEQGGVLQPFEYDPGPLGRQQVDIQVEYCGICHSDLSMIKNEWGMTQYPFVPGHEIVGIVAEIGSEVTTLRVG
QRVGLGWYSSSCMHCEWCMGGDHHLCLSAEGTIVGRPGGFADQVRADQSWIVPIPESIDSAVAGPLFCAGITVFQPIIQC
GVQPTDRVAVIGIGGLGHLALQFLNAWGCEVTALSTQPDKEAEARRLGAHHFVNTRDPAALQAIANSCDYIISTVNVSLE
WSIYLNALRPKGRLHLVGVAPDLSLPVFPLLAGQRSISGSPVGSPATITKMLNFVARHGLAPQTEVFPLAQVNEALEKLR
SQHPPYRLALKC
>Mature_332_residues
MVNAYAAFEQGGVLQPFEYDPGPLGRQQVDIQVEYCGICHSDLSMIKNEWGMTQYPFVPGHEIVGIVAEIGSEVTTLRVG
QRVGLGWYSSSCMHCEWCMGGDHHLCLSAEGTIVGRPGGFADQVRADQSWIVPIPESIDSAVAGPLFCAGITVFQPIIQC
GVQPTDRVAVIGIGGLGHLALQFLNAWGCEVTALSTQPDKEAEARRLGAHHFVNTRDPAALQAIANSCDYIISTVNVSLE
WSIYLNALRPKGRLHLVGVAPDLSLPVFPLLAGQRSISGSPVGSPATITKMLNFVARHGLAPQTEVFPLAQVNEALEKLR
SQHPPYRLALKC

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=351, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI71743840, Length=351, Percent_Identity=24.2165242165242, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073058, Length=351, Percent_Identity=24.2165242165242, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI34577061, Length=356, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082401, Length=334, Percent_Identity=51.1976047904192, Blast_Score=331, Evalue=3e-92,
Organism=Escherichia coli, GI1786518, Length=341, Percent_Identity=34.8973607038123, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI87081918, Length=305, Percent_Identity=29.5081967213115, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790045, Length=252, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788073, Length=320, Percent_Identity=21.875, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788407, Length=244, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786552, Length=355, Percent_Identity=27.887323943662, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082125, Length=317, Percent_Identity=24.2902208201893, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788075, Length=287, Percent_Identity=27.8745644599303, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787863, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790718, Length=271, Percent_Identity=26.9372693726937, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=331, Percent_Identity=29.3051359516616, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17562584, Length=333, Percent_Identity=26.4264264264264, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562582, Length=308, Percent_Identity=27.9220779220779, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=204, Percent_Identity=30.3921568627451, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=210, Percent_Identity=30.4761904761905, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323980, Length=330, Percent_Identity=31.5151515151515, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319949, Length=328, Percent_Identity=31.7073170731707, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323961, Length=301, Percent_Identity=31.8936877076412, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323729, Length=303, Percent_Identity=30.3630363036304, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319621, Length=312, Percent_Identity=31.0897435897436, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324486, Length=317, Percent_Identity=30.5993690851735, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319258, Length=309, Percent_Identity=27.831715210356, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35790; Mature: 35790

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNAYAAFEQGGVLQPFEYDPGPLGRQQVDIQVEYCGICHSDLSMIKNEWGMTQYPFVPG
CCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
HEIVGIVAEIGSEVTTLRVGQRVGLGWYSSSCMHCEWCMGGDHHLCLSAEGTIVGRPGGF
HHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCEEEEECCCCCEEEEECCCEEEECCCCC
ADQVRADQSWIVPIPESIDSAVAGPLFCAGITVFQPIIQCGVQPTDRVAVIGIGGLGHLA
HHHHCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHH
LQFLNAWGCEVTALSTQPDKEAEARRLGAHHFVNTRDPAALQAIANSCDYIISTVNVSLE
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEEE
WSIYLNALRPKGRLHLVGVAPDLSLPVFPLLAGQRSISGSPVGSPATITKMLNFVARHGL
EEEEEEEECCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
APQTEVFPLAQVNEALEKLRSQHPPYRLALKC
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MVNAYAAFEQGGVLQPFEYDPGPLGRQQVDIQVEYCGICHSDLSMIKNEWGMTQYPFVPG
CCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
HEIVGIVAEIGSEVTTLRVGQRVGLGWYSSSCMHCEWCMGGDHHLCLSAEGTIVGRPGGF
HHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCEEEEECCCCCEEEEECCCEEEECCCCC
ADQVRADQSWIVPIPESIDSAVAGPLFCAGITVFQPIIQCGVQPTDRVAVIGIGGLGHLA
HHHHCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHH
LQFLNAWGCEVTALSTQPDKEAEARRLGAHHFVNTRDPAALQAIANSCDYIISTVNVSLE
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEEE
WSIYLNALRPKGRLHLVGVAPDLSLPVFPLLAGQRSISGSPVGSPATITKMLNFVARHGL
EEEEEEEECCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
APQTEVFPLAQVNEALEKLRSQHPPYRLALKC
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]