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The map label for this gene is 158337904

Identifier: 158337904

GI number: 158337904

Start: 4826885

End: 4828315

Strand: Direct

Name: 158337904

Synonym: AM1_4792

Alternate gene names: NA

Gene position: 4826885-4828315 (Clockwise)

Preceding gene: 158337903

Following gene: 158337911

Centisome position: 74.22

GC content: 53.25

Gene sequence:

>1431_bases
ATGTCCAATCAACCCCGTACTCGCCAAGAACTCTACGATCGCGTCCGCCAAAGCTCCCGTGATGAGGTCATCCTAGAAGA
AATGGTGCGGTTAGGATTTTGGCCCGCCGAAGGCGAGATGCCCCAAGATCCAACGGATGAGATTCGACGTAAAGGAGAAA
TTCAGCGAGAACTGGCAGCACTGCGGGCCGAGAACCGCAAACTGCACAACGAAGCCGCCATTAAAAAGCAGCTCTACAAA
GAGCGACTCGCTGCGTCTAAAAAGAAACGCCAAGAAACCAAAGAACGGAGAGAGCAAGAACGACAGTCCCGAGCCGCTGC
ATGGCGGGATCGAAAAGCTCGGGATATTGTCTATCTGGGAACAGGAGTTTCCGGGGGCCTTAATCAGACCGAGTGCGATC
GGACCCGACTTCAGCAATATGGACTTCCTGCTTACGGAACAGCAGAAGAGATTGCCAAGGCCATGCAGATTAGCGTTGGC
CAGTTGCGCTTCTTAGCCTTTTCTCGGCGTACCGCCCAAATTTCCCACTATGTCCGCTTCAAAATCCCCAAGAAAACTGG
GGGAGAACGGCTGATTTCAGCCCCCATGCCCCGCCTGAAGCAGGCCCAATACTGGATTGCAGAAAAGCTTCTAGCAGCCA
TCCCCCTCCACGAAGCTGCTCATGGGTTTTGTTCAGGACGCTCCATCGTTACCAATGCAACGCCACACTTGGGGGCTGAT
GTGGTGATTAACCTCGATCTCCAAGATTTTTTCCCGTCTATTTCCTATCCCCGGATTAAAGGCTTATTTCGTTCCTTTGG
CTATAGCGAAGCTGCTGCCACGATTTTTGCCCTGCTCTGTACAGAACCAGATGTGGTGGAGGTGGGCTTGGATGGTCAGC
ATTACTATGTGGCCCAGTCTCAGCGACATTTACCCCAAGGGGCACCCACCAGCCCCATATTGACCAATCTGCTCTGTCGG
CGTCTAGATCGTCGGTTGACGGCCATGGCGGCAGAGTTGGGATATCGGTATACGCGCTACGCCGATGATCTAACCTTCTC
AGCCACAGGTCAGCCTCAGCAGCAGGTGGGCAAGCTGTTGCGAAGGACCCATGCCATTGTCACCCACGAAGGATTTACGA
TTCATCCCCAAAAGACACGGGTGCTTCGCAGTGGTCGACAACAAGAGGTGACAGGGGTGGTGGTCAACGAAAAGCTGAAC
GTTGACCGTAAAACCCTCAAGCGATTTCGGGCGTTGCTCCACCAAATTGAACAGTCAGGCTACGACGATCAACATTGGGG
TGGCCAACCAGTATCGTTTGCTCAGATCCAAGGCTATGCCAACTTTGTGGAGATGGTGAATCCTGAACGCGGAGCCCAGT
TCCAGGCTCAAGTTAAGCGAATTAAGCGCAAGTACCCACCCCGCGTTCAAGCCTTTAAACCAGCTTCTTGA

Upstream 100 bases:

>100_bases
TCCAGTCCGAAGAGGTTTACGAAGAGGCGCTGAACTGACCGGGTTTATTTTTTTCTAAATAGACCGCTATTTATATCATC
GAGTTCACCTTTCTGACTCC

Downstream 100 bases:

>100_bases
TTTCACCATAGGCACGATAGAAGCCACCGCGGGCAGATTCCCGCAGGTCTTCGACCACGTAGCGCGCTCCTGCTTCCCGC
ATCTCTTTGGGGAATTGGAC

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Mx162-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSNQPRTRQELYDRVRQSSRDEVILEEMVRLGFWPAEGEMPQDPTDEIRRKGEIQRELAALRAENRKLHNEAAIKKQLYK
ERLAASKKKRQETKERREQERQSRAAAWRDRKARDIVYLGTGVSGGLNQTECDRTRLQQYGLPAYGTAEEIAKAMQISVG
QLRFLAFSRRTAQISHYVRFKIPKKTGGERLISAPMPRLKQAQYWIAEKLLAAIPLHEAAHGFCSGRSIVTNATPHLGAD
VVINLDLQDFFPSISYPRIKGLFRSFGYSEAAATIFALLCTEPDVVEVGLDGQHYYVAQSQRHLPQGAPTSPILTNLLCR
RLDRRLTAMAAELGYRYTRYADDLTFSATGQPQQQVGKLLRRTHAIVTHEGFTIHPQKTRVLRSGRQQEVTGVVVNEKLN
VDRKTLKRFRALLHQIEQSGYDDQHWGGQPVSFAQIQGYANFVEMVNPERGAQFQAQVKRIKRKYPPRVQAFKPAS

Sequences:

>Translated_476_residues
MSNQPRTRQELYDRVRQSSRDEVILEEMVRLGFWPAEGEMPQDPTDEIRRKGEIQRELAALRAENRKLHNEAAIKKQLYK
ERLAASKKKRQETKERREQERQSRAAAWRDRKARDIVYLGTGVSGGLNQTECDRTRLQQYGLPAYGTAEEIAKAMQISVG
QLRFLAFSRRTAQISHYVRFKIPKKTGGERLISAPMPRLKQAQYWIAEKLLAAIPLHEAAHGFCSGRSIVTNATPHLGAD
VVINLDLQDFFPSISYPRIKGLFRSFGYSEAAATIFALLCTEPDVVEVGLDGQHYYVAQSQRHLPQGAPTSPILTNLLCR
RLDRRLTAMAAELGYRYTRYADDLTFSATGQPQQQVGKLLRRTHAIVTHEGFTIHPQKTRVLRSGRQQEVTGVVVNEKLN
VDRKTLKRFRALLHQIEQSGYDDQHWGGQPVSFAQIQGYANFVEMVNPERGAQFQAQVKRIKRKYPPRVQAFKPAS
>Mature_475_residues
SNQPRTRQELYDRVRQSSRDEVILEEMVRLGFWPAEGEMPQDPTDEIRRKGEIQRELAALRAENRKLHNEAAIKKQLYKE
RLAASKKKRQETKERREQERQSRAAAWRDRKARDIVYLGTGVSGGLNQTECDRTRLQQYGLPAYGTAEEIAKAMQISVGQ
LRFLAFSRRTAQISHYVRFKIPKKTGGERLISAPMPRLKQAQYWIAEKLLAAIPLHEAAHGFCSGRSIVTNATPHLGADV
VINLDLQDFFPSISYPRIKGLFRSFGYSEAAATIFALLCTEPDVVEVGLDGQHYYVAQSQRHLPQGAPTSPILTNLLCRR
LDRRLTAMAAELGYRYTRYADDLTFSATGQPQQQVGKLLRRTHAIVTHEGFTIHPQKTRVLRSGRQQEVTGVVVNEKLNV
DRKTLKRFRALLHQIEQSGYDDQHWGGQPVSFAQIQGYANFVEMVNPERGAQFQAQVKRIKRKYPPRVQAFKPAS

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 54335; Mature: 54204

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQPRTRQELYDRVRQSSRDEVILEEMVRLGFWPAEGEMPQDPTDEIRRKGEIQRELAA
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRAENRKLHNEAAIKKQLYKERLAASKKKRQETKERREQERQSRAAAWRDRKARDIVYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TGVSGGLNQTECDRTRLQQYGLPAYGTAEEIAKAMQISVGQLRFLAFSRRTAQISHYVRF
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KIPKKTGGERLISAPMPRLKQAQYWIAEKLLAAIPLHEAAHGFCSGRSIVTNATPHLGAD
ECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEECCCCCCCCCC
VVINLDLQDFFPSISYPRIKGLFRSFGYSEAAATIFALLCTEPDVVEVGLDGQHYYVAQS
EEEEEEHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEECH
QRHLPQGAPTSPILTNLLCRRLDRRLTAMAAELGYRYTRYADDLTFSATGQPQQQVGKLL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECCCCCCHHHHHHHH
RRTHAIVTHEGFTIHPQKTRVLRSGRQQEVTGVVVNEKLNVDRKTLKRFRALLHQIEQSG
HHHHHHEECCCEEECCHHHHHHHCCCHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YDDQHWGGQPVSFAQIQGYANFVEMVNPERGAQFQAQVKRIKRKYPPRVQAFKPAS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SNQPRTRQELYDRVRQSSRDEVILEEMVRLGFWPAEGEMPQDPTDEIRRKGEIQRELAA
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRAENRKLHNEAAIKKQLYKERLAASKKKRQETKERREQERQSRAAAWRDRKARDIVYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TGVSGGLNQTECDRTRLQQYGLPAYGTAEEIAKAMQISVGQLRFLAFSRRTAQISHYVRF
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KIPKKTGGERLISAPMPRLKQAQYWIAEKLLAAIPLHEAAHGFCSGRSIVTNATPHLGAD
ECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEECCCCCCCCCC
VVINLDLQDFFPSISYPRIKGLFRSFGYSEAAATIFALLCTEPDVVEVGLDGQHYYVAQS
EEEEEEHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEECH
QRHLPQGAPTSPILTNLLCRRLDRRLTAMAAELGYRYTRYADDLTFSATGQPQQQVGKLL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECCCCCCHHHHHHHH
RRTHAIVTHEGFTIHPQKTRVLRSGRQQEVTGVVVNEKLNVDRKTLKRFRALLHQIEQSG
HHHHHHEECCCEEECCHHHHHHHCCCHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YDDQHWGGQPVSFAQIQGYANFVEMVNPERGAQFQAQVKRIKRKYPPRVQAFKPAS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2465092; 2465091 [H]