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The map label for this gene is kapD [H]

Identifier: 158337902

GI number: 158337902

Start: 4825262

End: 4825813

Strand: Direct

Name: kapD [H]

Synonym: AM1_4789

Alternate gene names: 158337902

Gene position: 4825262-4825813 (Clockwise)

Preceding gene: 158337900

Following gene: 158337903

Centisome position: 74.19

GC content: 44.2

Gene sequence:

>552_bases
ATGAAAATTAGCCAGAAATATTACTTGATTGTCGATCTTGAAGCCACCTGTGCAGATGATAATTCCATTCCTCGCCGCAG
AATGGAGATGATTGAGATTGGAGCTGTGCTTCTCAACTCACAAACTCTGCAGATAGAAAGTGAATACCAGACCTTCATAA
AGCCCATTCTTCATCCTGTGCTGACTGAGTTTTGCAAATCTCTGACATCCATCTCTCAGCAGGATATTGAAAAGGCCCCA
CTTTTCCCGGCGGCTCTAAAAGATTTTCAATCTTGGTTTTACCCCTGTGGGAGTTATCTGTTTTGCTCTTGGGGAGATTA
TGATCGGCATCAATTTGTGCAGGATTGCCAGATGCATGGCGTTGGCTATCCCTTTCCGGGGGATCATCTCAATTTAAAGC
GAGCATTCTCTAGCGAGATCAACTCAAAAAAGAAGTTTGGTATGGCAGGCGCATTGACCGAATTAGGTCTAGAGCTTGAA
GGGGTTCATCATCGGGGTATAGATGACGCTCGAAATATTGCCCGCATTGTTCAAACTGCTTTTTCTGAGTGA

Upstream 100 bases:

>100_bases
TGACAGGGAAAGATCTAGAAACTACAAAAGAACTTATGTTTAGCTAGGCACCGAGTGTCCTATTCCTATAGGGGCCTGGG
GTGTCCCCTTCACGACGTCA

Downstream 100 bases:

>100_bases
GTCTCTAGAAAGTTCACAACAGGTGTTTCGCAATGAGTCCCCCTATTCAGAACAATATTGACCGAGCCGTGAGTCTAAGA
ACATGCTGTTTACCATTGTC

Product: exonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKISQKYYLIVDLEATCADDNSIPRRRMEMIEIGAVLLNSQTLQIESEYQTFIKPILHPVLTEFCKSLTSISQQDIEKAP
LFPAALKDFQSWFYPCGSYLFCSWGDYDRHQFVQDCQMHGVGYPFPGDHLNLKRAFSSEINSKKKFGMAGALTELGLELE
GVHHRGIDDARNIARIVQTAFSE

Sequences:

>Translated_183_residues
MKISQKYYLIVDLEATCADDNSIPRRRMEMIEIGAVLLNSQTLQIESEYQTFIKPILHPVLTEFCKSLTSISQQDIEKAP
LFPAALKDFQSWFYPCGSYLFCSWGDYDRHQFVQDCQMHGVGYPFPGDHLNLKRAFSSEINSKKKFGMAGALTELGLELE
GVHHRGIDDARNIARIVQTAFSE
>Mature_183_residues
MKISQKYYLIVDLEATCADDNSIPRRRMEMIEIGAVLLNSQTLQIESEYQTFIKPILHPVLTEFCKSLTSISQQDIEKAP
LFPAALKDFQSWFYPCGSYLFCSWGDYDRHQFVQDCQMHGVGYPFPGDHLNLKRAFSSEINSKKKFGMAGALTELGLELE
GVHHRGIDDARNIARIVQTAFSE

Specific function: Specifically inhibits the kinA pathway to sporulation [H]

COG id: COG5018

COG function: function code R; Inhibitor of the KinA pathway to sporulation, predicted exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI31543184, Length=179, Percent_Identity=33.5195530726257, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI218505674, Length=190, Percent_Identity=32.1052631578947, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI218505680, Length=190, Percent_Identity=32.1052631578947, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI74136559, Length=181, Percent_Identity=32.5966850828729, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI25148196, Length=183, Percent_Identity=31.1475409836066, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17541752, Length=187, Percent_Identity=33.1550802139037, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25148199, Length=183, Percent_Identity=31.1475409836066, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17541516, Length=187, Percent_Identity=33.1550802139037, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24657520, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24657528, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573607, Length=190, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330522, Length=190, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330524, Length=189, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: NA

Molecular weight: Translated: 20859; Mature: 20859

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISQKYYLIVDLEATCADDNSIPRRRMEMIEIGAVLLNSQTLQIESEYQTFIKPILHPV
CCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
LTEFCKSLTSISQQDIEKAPLFPAALKDFQSWFYPCGSYLFCSWGDYDRHQFVQDCQMHG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCC
VGYPFPGDHLNLKRAFSSEINSKKKFGMAGALTELGLELEGVHHRGIDDARNIARIVQTA
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHH
FSE
HCC
>Mature Secondary Structure
MKISQKYYLIVDLEATCADDNSIPRRRMEMIEIGAVLLNSQTLQIESEYQTFIKPILHPV
CCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
LTEFCKSLTSISQQDIEKAPLFPAALKDFQSWFYPCGSYLFCSWGDYDRHQFVQDCQMHG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCC
VGYPFPGDHLNLKRAFSSEINSKKKFGMAGALTELGLELEGVHHRGIDDARNIARIVQTA
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHH
FSE
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]