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The map label for this gene is ruvB

Identifier: 158337867

GI number: 158337867

Start: 4793436

End: 4794563

Strand: Reverse

Name: ruvB

Synonym: AM1_4753

Alternate gene names: 158337867

Gene position: 4794563-4793436 (Counterclockwise)

Preceding gene: 158337868

Following gene: 158337866

Centisome position: 73.72

GC content: 52.57

Gene sequence:

>1128_bases
ATGGCCATTGTCTCCTCTAAGCAATCTCCTCAACCGGATGGGTCGAAAAAGCCCTCTCAGGCAAAATCCGTCAAGAAGTC
TGTCGAGCACTCTAAGCCCCAACAGACGGATGCATTGTTGCAACCGGAAGCGGTGCAAGAAGAATTCGTTGGTAAGCAAG
ATGATAAGCTCAGACCCCAGCGGTTTGACGAATATATTGGCCAGCGAGAACTGAAAGAGGTTTTGGATATTGCCATCCAG
GCCACGAAATCCCGGCAAGAGGCTCTGGACCATCTCCTTCTCTATGGCCCCCCAGGGCTGGGAAAAACGACGATTTCTTT
GATTTTGGCAGCTGAGTTAGGGGTGAATTGTAAAGTCACCAGTGCGCCCGCCCTAGAACGTCCCCGGGATATTGTTGGTT
TGCTGGTTAACTTACAACCTCGGGATATCTTATTTATCGATGAAATTCATCGGCTGTCGAGGATGACGGAAGAGCTATTG
TATCCGGCGATGGAAGATTTTCGGCTTGATATCACGATTGGGAAAGGGCAGTCTGCACGGATTCGCAGTTTGCCTTTAAA
GCCTTTTACCCTAGTCGGTGCAACTACGCGGGTGGGAGCATTGACGTCGCCCTTGAGAGATCGCTTTGGCTTTGTCCAAC
GGTTGCGTTTTTATGAAGCCGATGAGCTGGGGCAAATTGTGTTGCGAACCGCAGATATCCTCAAGGCCAAAATCACTTCA
GATGCGGCAGAGGAAGTGGCCCGGCGGTCCAGGGGGACGCCTCGGATTGCCAACCGCTTGCTGAAACGGGTGCGGGATTA
TGCGGAGGTCAAGCATTCAGGGGAGATTACCCAAACGATTGCCCAGGAAGCCCTAGAGCTATTTAATGTCGATCCCTGTG
GCTTGGACTGGACGGATCGGCGGCTACTGACAGTGATGATTGAGCAATATAACGGTGGTCCGGTGGGCGTGGATACCTTA
GCAGCGGCGACAGGGGAAGACTCTCAGACCATTGAAGAGGTCTATGAACCCTATCTGATGCAGATTGGCTATCTGAACCG
CACGCCTAGGGGCCGAGTGGCGACGCCTGCAGCCTGGACTCATCTGGGATATCAGCCCCCCGATGAACAAATGCGATTGC
TGTCTTAG

Upstream 100 bases:

>100_bases
GTGGTCGCCACCCTGAAGCAAGTGGTCTGCGTTAAAGGATAGTGGGGGATTTGGGGGGATCTCCCACCCACTGCCTTTGG
CCGCTATGATGGAGGCTATT

Downstream 100 bases:

>100_bases
CAAGCCCCCTCAATACAACGAAGCACCATTGCATTGCAGAACCGCTGAATCCTTTAGACCTAGGCAAAACCCTCACCATT
TTGGAGGTCACCATGACAGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAIVSSKQSPQPDGSKKPSQAKSVKKSVEHSKPQQTDALLQPEAVQEEFVGKQDDKLRPQRFDEYIGQRELKEVLDIAIQ
ATKSRQEALDHLLLYGPPGLGKTTISLILAAELGVNCKVTSAPALERPRDIVGLLVNLQPRDILFIDEIHRLSRMTEELL
YPAMEDFRLDITIGKGQSARIRSLPLKPFTLVGATTRVGALTSPLRDRFGFVQRLRFYEADELGQIVLRTADILKAKITS
DAAEEVARRSRGTPRIANRLLKRVRDYAEVKHSGEITQTIAQEALELFNVDPCGLDWTDRRLLTVMIEQYNGGPVGVDTL
AAATGEDSQTIEEVYEPYLMQIGYLNRTPRGRVATPAAWTHLGYQPPDEQMRLLS

Sequences:

>Translated_375_residues
MAIVSSKQSPQPDGSKKPSQAKSVKKSVEHSKPQQTDALLQPEAVQEEFVGKQDDKLRPQRFDEYIGQRELKEVLDIAIQ
ATKSRQEALDHLLLYGPPGLGKTTISLILAAELGVNCKVTSAPALERPRDIVGLLVNLQPRDILFIDEIHRLSRMTEELL
YPAMEDFRLDITIGKGQSARIRSLPLKPFTLVGATTRVGALTSPLRDRFGFVQRLRFYEADELGQIVLRTADILKAKITS
DAAEEVARRSRGTPRIANRLLKRVRDYAEVKHSGEITQTIAQEALELFNVDPCGLDWTDRRLLTVMIEQYNGGPVGVDTL
AAATGEDSQTIEEVYEPYLMQIGYLNRTPRGRVATPAAWTHLGYQPPDEQMRLLS
>Mature_374_residues
AIVSSKQSPQPDGSKKPSQAKSVKKSVEHSKPQQTDALLQPEAVQEEFVGKQDDKLRPQRFDEYIGQRELKEVLDIAIQA
TKSRQEALDHLLLYGPPGLGKTTISLILAAELGVNCKVTSAPALERPRDIVGLLVNLQPRDILFIDEIHRLSRMTEELLY
PAMEDFRLDITIGKGQSARIRSLPLKPFTLVGATTRVGALTSPLRDRFGFVQRLRFYEADELGQIVLRTADILKAKITSD
AAEEVARRSRGTPRIANRLLKRVRDYAEVKHSGEITQTIAQEALELFNVDPCGLDWTDRRLLTVMIEQYNGGPVGVDTLA
AATGEDSQTIEEVYEPYLMQIGYLNRTPRGRVATPAAWTHLGYQPPDEQMRLLS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=315, Percent_Identity=58.0952380952381, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_ACAM1 (B0C2D5)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001519043.1
- ProteinModelPortal:   B0C2D5
- SMR:   B0C2D5
- GeneID:   5683553
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4753
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   AMAR329726:AM1_4753-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 41921; Mature: 41789

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVSSKQSPQPDGSKKPSQAKSVKKSVEHSKPQQTDALLQPEAVQEEFVGKQDDKLRPQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCHH
RFDEYIGQRELKEVLDIAIQATKSRQEALDHLLLYGPPGLGKTTISLILAAELGVNCKVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEC
SAPALERPRDIVGLLVNLQPRDILFIDEIHRLSRMTEELLYPAMEDFRLDITIGKGQSAR
CCCCCCCCHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCC
IRSLPLKPFTLVGATTRVGALTSPLRDRFGFVQRLRFYEADELGQIVLRTADILKAKITS
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
DAAEEVARRSRGTPRIANRLLKRVRDYAEVKHSGEITQTIAQEALELFNVDPCGLDWTDR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHH
RLLTVMIEQYNGGPVGVDTLAAATGEDSQTIEEVYEPYLMQIGYLNRTPRGRVATPAAWT
HHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
HLGYQPPDEQMRLLS
HCCCCCCHHHHHCCC
>Mature Secondary Structure 
AIVSSKQSPQPDGSKKPSQAKSVKKSVEHSKPQQTDALLQPEAVQEEFVGKQDDKLRPQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCHH
RFDEYIGQRELKEVLDIAIQATKSRQEALDHLLLYGPPGLGKTTISLILAAELGVNCKVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEC
SAPALERPRDIVGLLVNLQPRDILFIDEIHRLSRMTEELLYPAMEDFRLDITIGKGQSAR
CCCCCCCCHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCC
IRSLPLKPFTLVGATTRVGALTSPLRDRFGFVQRLRFYEADELGQIVLRTADILKAKITS
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
DAAEEVARRSRGTPRIANRLLKRVRDYAEVKHSGEITQTIAQEALELFNVDPCGLDWTDR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHH
RLLTVMIEQYNGGPVGVDTLAAATGEDSQTIEEVYEPYLMQIGYLNRTPRGRVATPAAWT
HHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
HLGYQPPDEQMRLLS
HCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA