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The map label for this gene is coxB [H]

Identifier: 158337737

GI number: 158337737

Start: 4654492

End: 4655478

Strand: Reverse

Name: coxB [H]

Synonym: AM1_4621

Alternate gene names: 158337737

Gene position: 4655478-4654492 (Counterclockwise)

Preceding gene: 158337742

Following gene: 158337736

Centisome position: 71.58

GC content: 49.85

Gene sequence:

>987_bases
GTGAAAGTTCCAACGGCGATTCTCACCTTAATTATTGGGATTTTAATTACCCTTGCGAGTCTTTGGGTCAGTCAAAACAA
TGATTTATTACTGCCCATCGCTGCAGCTTCTGAAGCGGCAGAAATCGATCGATTATTCGCATCGATGATGGCCATTGCCA
CGGGCCTATTTCTAATTGTTCAAGGGGCGTTGCTATATTCCTTATTCGCGTTTCGCCGTAAGTCAGATGATCAGACGGAT
GCTGAACCTGTGCATGGCAATGTGCCTTTAGAAATTGTCTGGACTGCCATTCCAGCAATGCTAGTGCTGTGGTTGGGAAT
CTATAGTTTCGATGTCTATCAGAGTATTGATAGCGTCGGTACGATGGGATCTCATAATATGGCCCATCAGCATGGCGATA
TGGAACGGGTGGCCGATGCAGATGCCGCCACCATGGTCACCGATCAAGGTCAGATGCCTTCTGGCGCGCTTAGCCAAGCA
GTGGCAACTGAAACCGTTGAACCATTGCAGGTCAATGTAGATGGTTTGCAATATGCTTGGCTATTTACGTATCCCGATAC
GGGCATCATCTCCGGCGAACTCCATCTACCCGCCAATCGCCCCGTAACCCTCAACATTTCGGCGAGGGATGTGATTCATG
CGTTTTGGGTACCTGAATTTCGATTGAAGCAAGATGCAGTGCCAGGTCAAGTCACTCACTTGAATTTTCAGCCTACAAAA
GAAGGGGTTTATCCCGTCATTTGTGCAGAGTTGTGTGGGGCGTATCACGGAGCAATGAAGACCCGCTCCATTGTCCACTC
TGGGGCTGAATACCAAGCTTGGGTGGATAGTCAGCTCGTAGCAAATACGTCGAGGGAGACGGTCGCTCAATCTGTAACCA
AGTCCCCTTTAGAACACCATGCTGCAGCGATGGGTATGCCTCATCACCTGCCTGACTCCCATCAGTCGGATTTAGCGCAG
GCTGCCCACTCCCCTTCAGCGTCCTGA

Upstream 100 bases:

>100_bases
TGATCTACCGTAGTAGGTGATGTTGAAGGTCTTGAAATAGGTGTTTAAATCTTCTTATCGTTTGGCCTGATATCCGCTCT
ATCACTACAGGAAAATCACT

Downstream 100 bases:

>100_bases
CAGGGCTATTTATTTTGACAATTAAGACAACGATTTCTGTGATCACCCCGGGATAAAGGATTGATTTATGACGGAAGCGC
AAGCACCCCATCTAGAAGAA

Product: cytochrome c oxidase II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKVPTAILTLIIGILITLASLWVSQNNDLLLPIAAASEAAEIDRLFASMMAIATGLFLIVQGALLYSLFAFRRKSDDQTD
AEPVHGNVPLEIVWTAIPAMLVLWLGIYSFDVYQSIDSVGTMGSHNMAHQHGDMERVADADAATMVTDQGQMPSGALSQA
VATETVEPLQVNVDGLQYAWLFTYPDTGIISGELHLPANRPVTLNISARDVIHAFWVPEFRLKQDAVPGQVTHLNFQPTK
EGVYPVICAELCGAYHGAMKTRSIVHSGAEYQAWVDSQLVANTSRETVAQSVTKSPLEHHAAAMGMPHHLPDSHQSDLAQ
AAHSPSAS

Sequences:

>Translated_328_residues
MKVPTAILTLIIGILITLASLWVSQNNDLLLPIAAASEAAEIDRLFASMMAIATGLFLIVQGALLYSLFAFRRKSDDQTD
AEPVHGNVPLEIVWTAIPAMLVLWLGIYSFDVYQSIDSVGTMGSHNMAHQHGDMERVADADAATMVTDQGQMPSGALSQA
VATETVEPLQVNVDGLQYAWLFTYPDTGIISGELHLPANRPVTLNISARDVIHAFWVPEFRLKQDAVPGQVTHLNFQPTK
EGVYPVICAELCGAYHGAMKTRSIVHSGAEYQAWVDSQLVANTSRETVAQSVTKSPLEHHAAAMGMPHHLPDSHQSDLAQ
AAHSPSAS
>Mature_328_residues
MKVPTAILTLIIGILITLASLWVSQNNDLLLPIAAASEAAEIDRLFASMMAIATGLFLIVQGALLYSLFAFRRKSDDQTD
AEPVHGNVPLEIVWTAIPAMLVLWLGIYSFDVYQSIDSVGTMGSHNMAHQHGDMERVADADAATMVTDQGQMPSGALSQA
VATETVEPLQVNVDGLQYAWLFTYPDTGIISGELHLPANRPVTLNISARDVIHAFWVPEFRLKQDAVPGQVTHLNFQPTK
EGVYPVICAELCGAYHGAMKTRSIVHSGAEYQAWVDSQLVANTSRETVAQSVTKSPLEHHAAAMGMPHHLPDSHQSDLAQ
AAHSPSAS

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:
GO:0004129: Cytochrome c oxidase subunit 2
GO:0005507: Cytochrome c oxidase subunit 2
GO:0006810: Cytochrome c oxidase subunit 2
GO:0009055: Cytochrome c oxidase subunit 2
GO:0016020: Cytochrome c oxidase subunit 2
GO:0016021: Cytochrome c oxidase subunit 2
GO:0016491: Cytochrome c oxidase subunit 2
GO:0020037: Cytochrome c oxidase subunit 2
GO:0022900: Cytochrome c oxidase subunit 2
GO:0022904: Cytochrome c oxidase subunit 2
GO:0046872: Cytochrome c oxidase subunit 2
GO:0055114: Cytochrome c oxidase subunit 2
GO:0070469: Cytochrome c oxidase subunit 2

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=261, Percent_Identity=22.9885057471264, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35455; Mature: 35455

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPTAILTLIIGILITLASLWVSQNNDLLLPIAAASEAAEIDRLFASMMAIATGLFLIV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
QGALLYSLFAFRRKSDDQTDAEPVHGNVPLEIVWTAIPAMLVLWLGIYSFDVYQSIDSVG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TMGSHNMAHQHGDMERVADADAATMVTDQGQMPSGALSQAVATETVEPLQVNVDGLQYAW
CCCCCCHHHHCCCHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEE
LFTYPDTGIISGELHLPANRPVTLNISARDVIHAFWVPEFRLKQDAVPGQVTHLNFQPTK
EEECCCCCEEECEEECCCCCCEEEEECHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCC
EGVYPVICAELCGAYHGAMKTRSIVHSGAEYQAWVDSQLVANTSRETVAQSVTKSPLEHH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AAAMGMPHHLPDSHQSDLAQAAHSPSAS
HHHHCCCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKVPTAILTLIIGILITLASLWVSQNNDLLLPIAAASEAAEIDRLFASMMAIATGLFLIV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
QGALLYSLFAFRRKSDDQTDAEPVHGNVPLEIVWTAIPAMLVLWLGIYSFDVYQSIDSVG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TMGSHNMAHQHGDMERVADADAATMVTDQGQMPSGALSQAVATETVEPLQVNVDGLQYAW
CCCCCCHHHHCCCHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEE
LFTYPDTGIISGELHLPANRPVTLNISARDVIHAFWVPEFRLKQDAVPGQVTHLNFQPTK
EEECCCCCEEECEEECCCCCCEEEEECHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCC
EGVYPVICAELCGAYHGAMKTRSIVHSGAEYQAWVDSQLVANTSRETVAQSVTKSPLEHH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AAAMGMPHHLPDSHQSDLAQAAHSPSAS
HHHHCCCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383492; 8387368; 8905231 [H]