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The map label for this gene is ctaD [H]

Identifier: 158337736

GI number: 158337736

Start: 4652760

End: 4654424

Strand: Reverse

Name: ctaD [H]

Synonym: AM1_4620

Alternate gene names: 158337736

Gene position: 4654424-4652760 (Counterclockwise)

Preceding gene: 158337737

Following gene: 158337735

Centisome position: 71.57

GC content: 49.85

Gene sequence:

>1665_bases
ATGACGGAAGCGCAAGCACCCCATCTAGAAGAAGTAGAGGTGACGCCTTGGCGCGAATACTTCAGCTTCAGTACGGACCA
TAAGGTGATTGGCATTCAATATCTGGTCACAAGCTTTGTGTTCTATCTGATTGGTGGACTTCTGGCTGAACTGGTACGGA
CTGAGTTGGCAACTCCCGCTTCAGATTTTGTGCCACGAGAGACCTACAACGAACTGTTCACCATGCATGCCACAATCATG
ATCTTTTTGTGGATCATCCCCACCCTCACGGGCGGCTTTGGCAATTTTTTGGTGCCGTTGATGATTGGGGCTAGGGATAT
GGCCTTCCCGAAACTGAATGCGATCGCATTCTGGATCATCCCTCCCACTAGCATTCTCTTGTTGTGCAGCTTCTTTGTCG
GCCCCGCCAGTGCAGGCTGGACCTCCTACCCGCCTTTGAGCTTAATGACCAACAAAGCAGGAGAAGCCATCTGGATTCTG
GGGGTCATTCTGCTGGGAACCTCATCGATTATGGCGGGACTTAATTTCTTGGTCACCATTCTTAAAATGCGCATTCCCAG
CATGACCTTGAATGATATGCCCCTGTTTTGCTGGGCTATGTTGGCGACTTCGGCCCTGCAGCTAGTGGCAACCCCTGTTT
TAAGTGGTGCAATGGTCTTGTTGGGCTTCGACTTATTGGTAGGCACCAACTTCTTTAACCCAGCAGGGGGTGGCGACCCA
ATTGTCTACCAGCATATGTTCTGGTTTTATTCCCATCCGGCGGTTTACATTATGATTCTGCCAGCCTTTGGCTTAATCTC
AGAGATTCTGCCGGTCCATGCTCGTAAGCCTATTTTTGGTTACCAGGCGATTGCCTATTCCAGTATTGCCATTAGCTTTT
TGGGTTTAATTGTCTGGGCTCACCATATGTTTACCAGTGGCACTCCCGACTGGTTAAGGATGTTCTTTATGATTGCCACG
ATGGTGATCGCCGTGCCCACGGGGATTAAGGTGTTTAGCTGGGTAGCAACGGTTTGGGGTGGCAAGCTGAACTTGTGCAG
TGCCATGCTGTTTGGGATGGCTTTTGTCTCCATGTTTGTGGTGGGTGGCCTCAGTGGGGTGATGGTGGCCTCAGTGCCTT
TTGATATTCACGTGCACGATACCTATTTTGTTGTTGCTCACCTGCATTACGTCTTATTTGGCGGCAGCGTATTTGGCATC
TATGCTGGTCTCTATCACTGGTTTCCTAAAATGACCGGACGGATGCTGAATGAATTCTGGGGCAAGGTGCATTTTGCCAT
GACCTTTGTCGGTTTCAATATTTGCTTTTTGCCCATGCATGTCTTGGGACTACAAGGGATGAATCGTCGAATTGCTGAAT
ATGATCCGAAGTTTGCAGCGCTGAATGTCGTATGTACGATTGGGTCCTATATTTTGGCGACATCAACGATTCCCTTTGTG
GTCAATGCGGTATGGAGCTGGTTGGCAGGCCCCAGAGCCAACAGTAATCCTTGGAAAGGACTGACTTTAGAGTGGACGGT
TCCTTCTCCCCCACCTGTAGAGAACTTTGAGGAAGATCCCGTTTTAGCGATTGGTCCCTATGATTATGGGACACCCAAGG
CCCTCGATTTTGTGGCGGCCACCCTAGCGCCTGCCCACGCCCTTGCAGCTGAAAGCTTAGAGTAG

Upstream 100 bases:

>100_bases
GCGCAGGCTGCCCACTCCCCTTCAGCGTCCTGACAGGGCTATTTATTTTGACAATTAAGACAACGATTTCTGTGATCACC
CCGGGATAAAGGATTGATTT

Downstream 100 bases:

>100_bases
TTCCTTTCTTAAACCTGAACACGTTAGCAACATTGGAGACCTATGCAAGGTTCAACAGCCGATCAAAATCAAGCCGACAT
CGCCTATGCCGCAACGGTGG

Product: cytochrome c oxidase I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MTEAQAPHLEEVEVTPWREYFSFSTDHKVIGIQYLVTSFVFYLIGGLLAELVRTELATPASDFVPRETYNELFTMHATIM
IFLWIIPTLTGGFGNFLVPLMIGARDMAFPKLNAIAFWIIPPTSILLLCSFFVGPASAGWTSYPPLSLMTNKAGEAIWIL
GVILLGTSSIMAGLNFLVTILKMRIPSMTLNDMPLFCWAMLATSALQLVATPVLSGAMVLLGFDLLVGTNFFNPAGGGDP
IVYQHMFWFYSHPAVYIMILPAFGLISEILPVHARKPIFGYQAIAYSSIAISFLGLIVWAHHMFTSGTPDWLRMFFMIAT
MVIAVPTGIKVFSWVATVWGGKLNLCSAMLFGMAFVSMFVVGGLSGVMVASVPFDIHVHDTYFVVAHLHYVLFGGSVFGI
YAGLYHWFPKMTGRMLNEFWGKVHFAMTFVGFNICFLPMHVLGLQGMNRRIAEYDPKFAALNVVCTIGSYILATSTIPFV
VNAVWSWLAGPRANSNPWKGLTLEWTVPSPPPVENFEEDPVLAIGPYDYGTPKALDFVAATLAPAHALAAESLE

Sequences:

>Translated_554_residues
MTEAQAPHLEEVEVTPWREYFSFSTDHKVIGIQYLVTSFVFYLIGGLLAELVRTELATPASDFVPRETYNELFTMHATIM
IFLWIIPTLTGGFGNFLVPLMIGARDMAFPKLNAIAFWIIPPTSILLLCSFFVGPASAGWTSYPPLSLMTNKAGEAIWIL
GVILLGTSSIMAGLNFLVTILKMRIPSMTLNDMPLFCWAMLATSALQLVATPVLSGAMVLLGFDLLVGTNFFNPAGGGDP
IVYQHMFWFYSHPAVYIMILPAFGLISEILPVHARKPIFGYQAIAYSSIAISFLGLIVWAHHMFTSGTPDWLRMFFMIAT
MVIAVPTGIKVFSWVATVWGGKLNLCSAMLFGMAFVSMFVVGGLSGVMVASVPFDIHVHDTYFVVAHLHYVLFGGSVFGI
YAGLYHWFPKMTGRMLNEFWGKVHFAMTFVGFNICFLPMHVLGLQGMNRRIAEYDPKFAALNVVCTIGSYILATSTIPFV
VNAVWSWLAGPRANSNPWKGLTLEWTVPSPPPVENFEEDPVLAIGPYDYGTPKALDFVAATLAPAHALAAESLE
>Mature_553_residues
TEAQAPHLEEVEVTPWREYFSFSTDHKVIGIQYLVTSFVFYLIGGLLAELVRTELATPASDFVPRETYNELFTMHATIMI
FLWIIPTLTGGFGNFLVPLMIGARDMAFPKLNAIAFWIIPPTSILLLCSFFVGPASAGWTSYPPLSLMTNKAGEAIWILG
VILLGTSSIMAGLNFLVTILKMRIPSMTLNDMPLFCWAMLATSALQLVATPVLSGAMVLLGFDLLVGTNFFNPAGGGDPI
VYQHMFWFYSHPAVYIMILPAFGLISEILPVHARKPIFGYQAIAYSSIAISFLGLIVWAHHMFTSGTPDWLRMFFMIATM
VIAVPTGIKVFSWVATVWGGKLNLCSAMLFGMAFVSMFVVGGLSGVMVASVPFDIHVHDTYFVVAHLHYVLFGGSVFGIY
AGLYHWFPKMTGRMLNEFWGKVHFAMTFVGFNICFLPMHVLGLQGMNRRIAEYDPKFAALNVVCTIGSYILATSTIPFVV
NAVWSWLAGPRANSNPWKGLTLEWTVPSPPPVENFEEDPVLAIGPYDYGTPKALDFVAATLAPAHALAAESLE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=503, Percent_Identity=44.7316103379722, Blast_Score=402, Evalue=1e-112,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=39.6887159533074, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6226519, Length=526, Percent_Identity=40.3041825095057, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=42.7672955974843, Blast_Score=261, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6226523, Length=242, Percent_Identity=38.4297520661157, Blast_Score=158, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61032; Mature: 60900

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAQAPHLEEVEVTPWREYFSFSTDHKVIGIQYLVTSFVFYLIGGLLAELVRTELATPA
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SDFVPRETYNELFTMHATIMIFLWIIPTLTGGFGNFLVPLMIGARDMAFPKLNAIAFWII
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
PPTSILLLCSFFVGPASAGWTSYPPLSLMTNKAGEAIWILGVILLGTSSIMAGLNFLVTI
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKMRIPSMTLNDMPLFCWAMLATSALQLVATPVLSGAMVLLGFDLLVGTNFFNPAGGGDP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IVYQHMFWFYSHPAVYIMILPAFGLISEILPVHARKPIFGYQAIAYSSIAISFLGLIVWA
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
HHMFTSGTPDWLRMFFMIATMVIAVPTGIKVFSWVATVWGGKLNLCSAMLFGMAFVSMFV
HHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGGLSGVMVASVPFDIHVHDTYFVVAHLHYVLFGGSVFGIYAGLYHWFPKMTGRMLNEFW
HHCCCCCEEEECCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKVHFAMTFVGFNICFLPMHVLGLQGMNRRIAEYDPKFAALNVVCTIGSYILATSTIPFV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VNAVWSWLAGPRANSNPWKGLTLEWTVPSPPPVENFEEDPVLAIGPYDYGTPKALDFVAA
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
TLAPAHALAAESLE
HHHHHHHHHHHCCC
>Mature Secondary Structure 
TEAQAPHLEEVEVTPWREYFSFSTDHKVIGIQYLVTSFVFYLIGGLLAELVRTELATPA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SDFVPRETYNELFTMHATIMIFLWIIPTLTGGFGNFLVPLMIGARDMAFPKLNAIAFWII
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
PPTSILLLCSFFVGPASAGWTSYPPLSLMTNKAGEAIWILGVILLGTSSIMAGLNFLVTI
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKMRIPSMTLNDMPLFCWAMLATSALQLVATPVLSGAMVLLGFDLLVGTNFFNPAGGGDP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IVYQHMFWFYSHPAVYIMILPAFGLISEILPVHARKPIFGYQAIAYSSIAISFLGLIVWA
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
HHMFTSGTPDWLRMFFMIATMVIAVPTGIKVFSWVATVWGGKLNLCSAMLFGMAFVSMFV
HHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGGLSGVMVASVPFDIHVHDTYFVVAHLHYVLFGGSVFGIYAGLYHWFPKMTGRMLNEFW
HHCCCCCEEEECCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKVHFAMTFVGFNICFLPMHVLGLQGMNRRIAEYDPKFAALNVVCTIGSYILATSTIPFV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VNAVWSWLAGPRANSNPWKGLTLEWTVPSPPPVENFEEDPVLAIGPYDYGTPKALDFVAA
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
TLAPAHALAAESLE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]