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The map label for this gene is bcsA [H]

Identifier: 158337632

GI number: 158337632

Start: 4538940

End: 4541090

Strand: Direct

Name: bcsA [H]

Synonym: AM1_4514

Alternate gene names: 158337632

Gene position: 4538940-4541090 (Clockwise)

Preceding gene: 158337631

Following gene: 158337634

Centisome position: 69.79

GC content: 48.81

Gene sequence:

>2151_bases
ATGTTGAAACGAACTGAGATCGATGGGCTGGAACGGATTGTCTGGGGCTTAGTGATTATCCTTGGGGGCTTTTGGCTATG
GAGCCAGTTTCAAGAACGATTGATTCTGGCTGATTTAGCTACACTGTGGCAACAGATGCAGGCCGTATTCACCCCTGATG
CGAATCGTCTCGATCGGCTATTGTTGCCAACCGCAATTGGCGGTACCTTTGTTTTTTGCCTTAAAACCATCAGTCCCAGA
CCTCTTTTGTGGAGCCGAGCCACCATTTCCATCCTGTTGGTGGGGCTGGGCGTTCGTTATGAGCTGTGGCGCTTATTTAA
TACTTTGAATTTGTCCGACCCTCTCAATGGCACTCTCAGCATTTTGCTGTTTGTCATGGAGTTAATGGCCTTCACCAACA
CGGCAGCGTTTATGCTGCAAACCATCCCCAGCATTGATCGAAGTCCAGAAGCCGATCACCTGTCTAAGGCCGTCATTAGC
GGAGCGTATCAACCCTGGGTGGACGTTTTAATTCCCACCTATAATGAACCACCTGACGTCCTCCGACGGACTATTATCGG
CTGCCAGGCCATGAAGTATGACCACAAGCGGGTTTTCCTTTTGGATGATCTGCGGCGTCCTCATATTCGCGAGCTGGCTC
AAGAGCTGGATTGCCACTACATCATCCGTCCCAATAATGACCATGCGAAAGCTGGAAATCTCAACCATGCGATCGCAAAA
ACAGACGGAGACTTAATCGTTGTTTTTGATGCCGATTTTATCCCCACCACCAACTTTTTAACTCGGACAGTCGGGTTCTT
TCAGGACGAAAAAGTCGCCTTACTACAAACCCCTCAGAACTTTTACAACGAGGACCCCATTGGCGTCAATCTAGGGCTGC
AAGAGGTACTCACCAACGAACAAGCCTTGTTCTTTCGCTATATCCAACCCAGTCGAGATGTCACCAACTCTGTGATTTGC
TGTGGATCTTCCTTTGTTATTCGGCGCACGGCATTAGCCGAGATTGGCGGTATTCCCACCGAAAGTATCACCGAAGACTT
CTTTACTTCTTTGAAATTACAGTCCTTGGGCTACAAGATTAAATATCTCAATGAAGCCCTCTCGGCTGGCATGTCTCCTG
AGAATATGGGCGCTTACATTGACCAGCGCTTACGGTGGGGGCAGGGAACCTTGCAGTCTATGTTTTGCCCGGCCAATGTC
TTCACCATTCCCGGATTGAACCTCTTACAGCGGGTGTCCCATTCCCTAGGATTACTGTACTGGTGCCTTTCTGTCCCTCG
GTTCATCTTTTTGGTGATGCCCCTGTCCTACCTACTGTTTGAACTCGCCCCTCTGCGAGCAACGATTGATGGGGTCCTAT
TTTTCTACCTACCCTATTTTGTTTGTAATGCCATCTCTTTTTCATGGATGACCGAAGGACGGCGTTCTGCTTTTTGGTCC
GATGTTTATGAGACCATCCTCTGCATTCCGATGATGCTAACGGTGATTCAAACCCTGAGGAACCCCTTTGGCAAAGCCTT
TAAGGTGACCCCCAAAGGAATCGCGGCCAATCGCTTACATATCAATTGGCACCTCCTCTGGCCCTTGGTGCTCTTGATCG
TCTTGTCCTTGTTTGGTTTGGGCATGCGTATCTTTTATGCCCCTTGGAGTACGGCCAACCCAGATAGCCTCAGAATTAAT
ATTGTGTGGACCACCTATAATCTGATCCTCCTGTACATTTGCGTTCTGGTGAATATCGATGTGCCTCAGCGGCAACACTC
TCGATTTGACCGTCAGTTTCCCTGCGAGCTGCAAATTAACGGGGAATGGTTATTAGGGCGCAGCATCAACATCTCAGAAG
GGGGAGCCGCTGTTCGCTTAAATCGGAAATGGAAACAACCTCCCACCGATAAGTTAGGGGTATTGAGGATTCCTGGCTTG
AAAACGGAACTAAAAGTTGAAATTCGCTGGAAGCAAAATAGCGATGCCGGACCATTTTTTGTGGGCTTGCGGTTTATTGA
ATGTGATGTCGTGCAGTTGCGATCGCTGATCCCGTTTCTCTACTGCCAACCTAACCAATGGATCGAACAAAAAGTCCCCG
AGCATTTAACCGTTTGGGCTCTCTTTCAATCCGTTTTCCGCCTCTATGCCTTAGCCGAAAGCCGTGGATAG

Upstream 100 bases:

>100_bases
TTGCCGTAAGGATTATGCTGGCCTCCGATGACCTGAAGCCTGAGCGGTTCTGTAGTGTCGGCCGCAGTGTCGAAGTTGTC
GTCTCTCGCTAAGGCCATCC

Downstream 100 bases:

>100_bases
ATCCCATCATGAAGCGGGGAGGGCGGGAGACCAAATATCTTTGTAGTAGCTTTCTAAACAGTGCTTCATAATGCCGTTAT
GGTTAAACGCCAACTGCATA

Product: glycosyl transferase, group 2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MLKRTEIDGLERIVWGLVIILGGFWLWSQFQERLILADLATLWQQMQAVFTPDANRLDRLLLPTAIGGTFVFCLKTISPR
PLLWSRATISILLVGLGVRYELWRLFNTLNLSDPLNGTLSILLFVMELMAFTNTAAFMLQTIPSIDRSPEADHLSKAVIS
GAYQPWVDVLIPTYNEPPDVLRRTIIGCQAMKYDHKRVFLLDDLRRPHIRELAQELDCHYIIRPNNDHAKAGNLNHAIAK
TDGDLIVVFDADFIPTTNFLTRTVGFFQDEKVALLQTPQNFYNEDPIGVNLGLQEVLTNEQALFFRYIQPSRDVTNSVIC
CGSSFVIRRTALAEIGGIPTESITEDFFTSLKLQSLGYKIKYLNEALSAGMSPENMGAYIDQRLRWGQGTLQSMFCPANV
FTIPGLNLLQRVSHSLGLLYWCLSVPRFIFLVMPLSYLLFELAPLRATIDGVLFFYLPYFVCNAISFSWMTEGRRSAFWS
DVYETILCIPMMLTVIQTLRNPFGKAFKVTPKGIAANRLHINWHLLWPLVLLIVLSLFGLGMRIFYAPWSTANPDSLRIN
IVWTTYNLILLYICVLVNIDVPQRQHSRFDRQFPCELQINGEWLLGRSINISEGGAAVRLNRKWKQPPTDKLGVLRIPGL
KTELKVEIRWKQNSDAGPFFVGLRFIECDVVQLRSLIPFLYCQPNQWIEQKVPEHLTVWALFQSVFRLYALAESRG

Sequences:

>Translated_716_residues
MLKRTEIDGLERIVWGLVIILGGFWLWSQFQERLILADLATLWQQMQAVFTPDANRLDRLLLPTAIGGTFVFCLKTISPR
PLLWSRATISILLVGLGVRYELWRLFNTLNLSDPLNGTLSILLFVMELMAFTNTAAFMLQTIPSIDRSPEADHLSKAVIS
GAYQPWVDVLIPTYNEPPDVLRRTIIGCQAMKYDHKRVFLLDDLRRPHIRELAQELDCHYIIRPNNDHAKAGNLNHAIAK
TDGDLIVVFDADFIPTTNFLTRTVGFFQDEKVALLQTPQNFYNEDPIGVNLGLQEVLTNEQALFFRYIQPSRDVTNSVIC
CGSSFVIRRTALAEIGGIPTESITEDFFTSLKLQSLGYKIKYLNEALSAGMSPENMGAYIDQRLRWGQGTLQSMFCPANV
FTIPGLNLLQRVSHSLGLLYWCLSVPRFIFLVMPLSYLLFELAPLRATIDGVLFFYLPYFVCNAISFSWMTEGRRSAFWS
DVYETILCIPMMLTVIQTLRNPFGKAFKVTPKGIAANRLHINWHLLWPLVLLIVLSLFGLGMRIFYAPWSTANPDSLRIN
IVWTTYNLILLYICVLVNIDVPQRQHSRFDRQFPCELQINGEWLLGRSINISEGGAAVRLNRKWKQPPTDKLGVLRIPGL
KTELKVEIRWKQNSDAGPFFVGLRFIECDVVQLRSLIPFLYCQPNQWIEQKVPEHLTVWALFQSVFRLYALAESRG
>Mature_716_residues
MLKRTEIDGLERIVWGLVIILGGFWLWSQFQERLILADLATLWQQMQAVFTPDANRLDRLLLPTAIGGTFVFCLKTISPR
PLLWSRATISILLVGLGVRYELWRLFNTLNLSDPLNGTLSILLFVMELMAFTNTAAFMLQTIPSIDRSPEADHLSKAVIS
GAYQPWVDVLIPTYNEPPDVLRRTIIGCQAMKYDHKRVFLLDDLRRPHIRELAQELDCHYIIRPNNDHAKAGNLNHAIAK
TDGDLIVVFDADFIPTTNFLTRTVGFFQDEKVALLQTPQNFYNEDPIGVNLGLQEVLTNEQALFFRYIQPSRDVTNSVIC
CGSSFVIRRTALAEIGGIPTESITEDFFTSLKLQSLGYKIKYLNEALSAGMSPENMGAYIDQRLRWGQGTLQSMFCPANV
FTIPGLNLLQRVSHSLGLLYWCLSVPRFIFLVMPLSYLLFELAPLRATIDGVLFFYLPYFVCNAISFSWMTEGRRSAFWS
DVYETILCIPMMLTVIQTLRNPFGKAFKVTPKGIAANRLHINWHLLWPLVLLIVLSLFGLGMRIFYAPWSTANPDSLRIN
IVWTTYNLILLYICVLVNIDVPQRQHSRFDRQFPCELQINGEWLLGRSINISEGGAAVRLNRKWKQPPTDKLGVLRIPGL
KTELKVEIRWKQNSDAGPFFVGLRFIECDVVQLRSLIPFLYCQPNQWIEQKVPEHLTVWALFQSVFRLYALAESRG

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component responsible for the structural integrity and rigidity of self-supporting mats characteristic of the "wrink

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=549, Percent_Identity=32.6047358834244, Blast_Score=300, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR005150
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03552 Cellulose_synt; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 81838; Mature: 81838

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRTEIDGLERIVWGLVIILGGFWLWSQFQERLILADLATLWQQMQAVFTPDANRLDRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLPTAIGGTFVFCLKTISPRPLLWSRATISILLVGLGVRYELWRLFNTLNLSDPLNGTLS
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHH
ILLFVMELMAFTNTAAFMLQTIPSIDRSPEADHLSKAVISGAYQPWVDVLIPTYNEPPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCHHH
LRRTIIGCQAMKYDHKRVFLLDDLRRPHIRELAQELDCHYIIRPNNDHAKAGNLNHAIAK
HHHHHHHHHHEECCCCEEEEEHHCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEE
TDGDLIVVFDADFIPTTNFLTRTVGFFQDEKVALLQTPQNFYNEDPIGVNLGLQEVLTNE
CCCCEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCHHHCCCCCCEECCCHHHHHCCC
QALFFRYIQPSRDVTNSVICCGSSFVIRRTALAEIGGIPTESITEDFFTSLKLQSLGYKI
CEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHH
KYLNEALSAGMSPENMGAYIDQRLRWGQGTLQSMFCPANVFTIPGLNLLQRVSHSLGLLY
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHH
WCLSVPRFIFLVMPLSYLLFELAPLRATIDGVLFFYLPYFVCNAISFSWMTEGRRSAFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
DVYETILCIPMMLTVIQTLRNPFGKAFKVTPKGIAANRLHINWHLLWPLVLLIVLSLFGL
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHCC
GMRIFYAPWSTANPDSLRINIVWTTYNLILLYICVLVNIDVPQRQHSRFDRQFPCELQIN
CEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEC
GEWLLGRSINISEGGAAVRLNRKWKQPPTDKLGVLRIPGLKTELKVEIRWKQNSDAGPFF
CCEEECCEECCCCCCCEEEECCCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCEE
VGLRFIECDVVQLRSLIPFLYCQPNQWIEQKVPEHLTVWALFQSVFRLYALAESRG
EEEEEEHHHHHHHHHHHHEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKRTEIDGLERIVWGLVIILGGFWLWSQFQERLILADLATLWQQMQAVFTPDANRLDRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLPTAIGGTFVFCLKTISPRPLLWSRATISILLVGLGVRYELWRLFNTLNLSDPLNGTLS
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHH
ILLFVMELMAFTNTAAFMLQTIPSIDRSPEADHLSKAVISGAYQPWVDVLIPTYNEPPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCHHH
LRRTIIGCQAMKYDHKRVFLLDDLRRPHIRELAQELDCHYIIRPNNDHAKAGNLNHAIAK
HHHHHHHHHHEECCCCEEEEEHHCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEE
TDGDLIVVFDADFIPTTNFLTRTVGFFQDEKVALLQTPQNFYNEDPIGVNLGLQEVLTNE
CCCCEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCHHHCCCCCCEECCCHHHHHCCC
QALFFRYIQPSRDVTNSVICCGSSFVIRRTALAEIGGIPTESITEDFFTSLKLQSLGYKI
CEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHH
KYLNEALSAGMSPENMGAYIDQRLRWGQGTLQSMFCPANVFTIPGLNLLQRVSHSLGLLY
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHH
WCLSVPRFIFLVMPLSYLLFELAPLRATIDGVLFFYLPYFVCNAISFSWMTEGRRSAFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
DVYETILCIPMMLTVIQTLRNPFGKAFKVTPKGIAANRLHINWHLLWPLVLLIVLSLFGL
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHCC
GMRIFYAPWSTANPDSLRINIVWTTYNLILLYICVLVNIDVPQRQHSRFDRQFPCELQIN
CEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEC
GEWLLGRSINISEGGAAVRLNRKWKQPPTDKLGVLRIPGLKTELKVEIRWKQNSDAGPFF
CCEEECCEECCCCCCCEEEECCCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCEE
VGLRFIECDVVQLRSLIPFLYCQPNQWIEQKVPEHLTVWALFQSVFRLYALAESRG
EEEEEEHHHHHHHHHHHHEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12019221 [H]