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The map label for this gene is gapA [H]

Identifier: 158337490

GI number: 158337490

Start: 4398773

End: 4399777

Strand: Direct

Name: gapA [H]

Synonym: AM1_4369

Alternate gene names: 158337490

Gene position: 4398773-4399777 (Clockwise)

Preceding gene: 158337489

Following gene: 158337493

Centisome position: 67.63

GC content: 47.86

Gene sequence:

>1005_bases
GTGATTAGAGTAGCGATCAACGGGTTCGGGAGAATTGGACGAAATTTTATGCGTTGTTGGCTTTTACGGCCGAACAGCAA
CATCGAGATTGTCGGATTAAATGATACTTCTGACCCCAAAACAAATGCCCACCTGTTGACCTATGACTCCATGCTGGGTC
GTTTAGATGCAGACATTAAAGCAGTCGATAACACGATTGTCGCGAATGGCCATGTCATTAAATGTGTCTCTGATCGGAAC
CCTGCTAACCTGCCTTGGAAAGATTGGGACATCGATCTAGTGATCGAATCTACAGGCGTGTTTGTCACCAAAGAAGGAGC
GAGCAAGCATATTGAAGCTGGCGCCAAAAAAGTATTAATCACAGCCCCTGGTAAGGGTGGTGTGGGTATGTATGTGGTTG
GGGTAAACCATGAGGATTATGATCCCAGCGAGCCCATTCTCAGTAATGCCAGTTGTACAACCAACTGTTTGGCCCCTGTG
GTTAAAATCTTGCATGAGCAGTTTGGAATTGTTCATGGCTTGATGACCACCACTCACAGCTACACTGGCGACCAGCGCAT
TCTAGATGCCAGCCACCGAGATTTGCGACGGGCTCGTGCTGCTGCAGTTAACATTGTGCCAACTTCCACTGGTGCTGCCA
AAGCAGTGGGTACTGTGATTCCTGCACTGCAAGGGAAGCTCAACGGTATTGCCTTGCGGGTGCCAACCCCTAACGTGTCA
GTTTGTGACTTTGTTGCCCAAACTGAGAAGCCAGCGATTGCTGAGTCTGTTAATGAAGTTCTTAAGCAAGCGTCTGAAAG
CTCAATGAAAGGAATCATTGCTTTCAACGAAGAGCCTTTGGTCTCAGGTGACTTCAAGGGACATGATTGTTCTTCTATTG
TTGATGGTTCCCTTACCATGGGCATGGGCGGCAACATGATCAAGGTTGTAGCTTGGTATGACAATGAGTGGGGTTATAGT
CAGCGCGTGCTTGACCTAGCTGAGTATGTTGCTCAGAAGTGGTAA

Upstream 100 bases:

>100_bases
CAAAGTCTTTAGAGAATAGGGCTGCCTTGTACGATATGATGATTGAGGGTCACTACTGGCTTGACTATAGACTATACATT
GAACATAAGGATAAGACGCA

Downstream 100 bases:

>100_bases
ATCTCACGCTCTGGGTTCTTGATGCCAGAGTACAATGATTCAAATAAAACCCCTCATCTGGAAATAGGTGAGGGGTTTCT
ATGTGTAGCAAGATCTATCT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIRVAINGFGRIGRNFMRCWLLRPNSNIEIVGLNDTSDPKTNAHLLTYDSMLGRLDADIKAVDNTIVANGHVIKCVSDRN
PANLPWKDWDIDLVIESTGVFVTKEGASKHIEAGAKKVLITAPGKGGVGMYVVGVNHEDYDPSEPILSNASCTTNCLAPV
VKILHEQFGIVHGLMTTTHSYTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVGTVIPALQGKLNGIALRVPTPNVS
VCDFVAQTEKPAIAESVNEVLKQASESSMKGIIAFNEEPLVSGDFKGHDCSSIVDGSLTMGMGGNMIKVVAWYDNEWGYS
QRVLDLAEYVAQKW

Sequences:

>Translated_334_residues
MIRVAINGFGRIGRNFMRCWLLRPNSNIEIVGLNDTSDPKTNAHLLTYDSMLGRLDADIKAVDNTIVANGHVIKCVSDRN
PANLPWKDWDIDLVIESTGVFVTKEGASKHIEAGAKKVLITAPGKGGVGMYVVGVNHEDYDPSEPILSNASCTTNCLAPV
VKILHEQFGIVHGLMTTTHSYTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVGTVIPALQGKLNGIALRVPTPNVS
VCDFVAQTEKPAIAESVNEVLKQASESSMKGIIAFNEEPLVSGDFKGHDCSSIVDGSLTMGMGGNMIKVVAWYDNEWGYS
QRVLDLAEYVAQKW
>Mature_334_residues
MIRVAINGFGRIGRNFMRCWLLRPNSNIEIVGLNDTSDPKTNAHLLTYDSMLGRLDADIKAVDNTIVANGHVIKCVSDRN
PANLPWKDWDIDLVIESTGVFVTKEGASKHIEAGAKKVLITAPGKGGVGMYVVGVNHEDYDPSEPILSNASCTTNCLAPV
VKILHEQFGIVHGLMTTTHSYTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVGTVIPALQGKLNGIALRVPTPNVS
VCDFVAQTEKPAIAESVNEVLKQASESSMKGIIAFNEEPLVSGDFKGHDCSSIVDGSLTMGMGGNMIKVVAWYDNEWGYS
QRVLDLAEYVAQKW

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=46.4071856287425, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=45.0746268656716, Blast_Score=299, Evalue=2e-81,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=48.4939759036145, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=41.1042944785276, Blast_Score=267, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=46.4705882352941, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=46.4705882352941, Blast_Score=296, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=47.3372781065089, Blast_Score=293, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=47.3372781065089, Blast_Score=293, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=49.7005988023952, Blast_Score=328, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=50, Blast_Score=327, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=49.702380952381, Blast_Score=327, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=45.9214501510574, Blast_Score=297, Evalue=5e-81,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=44.4776119402985, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=44.4776119402985, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=43.8805970149254, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=43.8805970149254, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36055; Mature: 36055

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAINGFGRIGRNFMRCWLLRPNSNIEIVGLNDTSDPKTNAHLLTYDSMLGRLDADIK
CEEEEECCCHHHHHHEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCHH
AVDNTIVANGHVIKCVSDRNPANLPWKDWDIDLVIESTGVFVTKEGASKHIEAGAKKVLI
HHCCEEEECCEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHCCCCEEEE
TAPGKGGVGMYVVGVNHEDYDPSEPILSNASCTTNCLAPVVKILHEQFGIVHGLMTTTHS
ECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
YTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVGTVIPALQGKLNGIALRVPTPNVS
CCCCCCEECCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
VCDFVAQTEKPAIAESVNEVLKQASESSMKGIIAFNEEPLVSGDFKGHDCSSIVDGSLTM
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHCCCEEE
GMGGNMIKVVAWYDNEWGYSQRVLDLAEYVAQKW
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRVAINGFGRIGRNFMRCWLLRPNSNIEIVGLNDTSDPKTNAHLLTYDSMLGRLDADIK
CEEEEECCCHHHHHHEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCHH
AVDNTIVANGHVIKCVSDRNPANLPWKDWDIDLVIESTGVFVTKEGASKHIEAGAKKVLI
HHCCEEEECCEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHCCCCEEEE
TAPGKGGVGMYVVGVNHEDYDPSEPILSNASCTTNCLAPVVKILHEQFGIVHGLMTTTHS
ECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
YTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVGTVIPALQGKLNGIALRVPTPNVS
CCCCCCEECCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
VCDFVAQTEKPAIAESVNEVLKQASESSMKGIIAFNEEPLVSGDFKGHDCSSIVDGSLTM
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHCCCEEE
GMGGNMIKVVAWYDNEWGYSQRVLDLAEYVAQKW
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]