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The map label for this gene is 158337472

Identifier: 158337472

GI number: 158337472

Start: 4380776

End: 4381336

Strand: Direct

Name: 158337472

Synonym: AM1_4351

Alternate gene names: NA

Gene position: 4380776-4381336 (Clockwise)

Preceding gene: 158337471

Following gene: 158337474

Centisome position: 67.36

GC content: 55.26

Gene sequence:

>561_bases
ATGCCCATTCTCGATTTACCCCCCGATCATCCTCAGATTCACAGGGACGTCGCGACTTTGTTGGTGGATGGCTTTCGTGA
AAATTGGCCCGAGGCTTGGCCCCATCTAGAGGCTGGTCTGCTAGAAGTACAAGCATCTTTACAGCCAGGTCGGATTAGTC
GGATTGCGATCAACCGGGAAGAACAGGTCCTGGGTTGGATTGGCGGCCTGCCCAGGTATGCGGGCCATGTTTGGGAGCTG
CATCCCCTGGTCGTTAAGGCATCAGAGCGGGGCCAAGGGTGGGGGCGTCGCTTAGTCGCCGATTTAGAAACCTGCGTGCA
GCAACGGGGTGGCTTGACCCTCTGGGTGGGGACTGATGATGAGACCGGCCAAACGAATTTGAGTCATGCCAACCTCTACC
CCAATGTGCTGGAACATCTGGCCCAGCTTCAAAACCTGCATCAGCACCCCTATGAGTTCTACCAAAAGTGTGGATTTTCG
GTTGTTGGGGTGATGCCGGATGCCAATGGACGGGGTAAGCCGGATATTTACATGGCGAAAGCGATCACGCCTAAACCCTA
A

Upstream 100 bases:

>100_bases
AATATTGACAATGGGTTTGGTGCGGCCATGTTAGCGGGTCAGATTTTGAGGACAGCCGTTCAGCTCCAGACTTCACAGTC
GGAAAAGTCTGAGTAGATAG

Downstream 100 bases:

>100_bases
TCTCTATTTTTGGTGGTGGACTTCAATCACTGTGTGAACGTTTCCTCTGGGCAGGAAGTCACCTTTTACCGTGATCTCCA
AGGGATCACAGGCGGCCACA

Product: aminoglycoside N(6')-acetyltransferase

Products: NA

Alternate protein names: AAC(6') [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MPILDLPPDHPQIHRDVATLLVDGFRENWPEAWPHLEAGLLEVQASLQPGRISRIAINREEQVLGWIGGLPRYAGHVWEL
HPLVVKASERGQGWGRRLVADLETCVQQRGGLTLWVGTDDETGQTNLSHANLYPNVLEHLAQLQNLHQHPYEFYQKCGFS
VVGVMPDANGRGKPDIYMAKAITPKP

Sequences:

>Translated_186_residues
MPILDLPPDHPQIHRDVATLLVDGFRENWPEAWPHLEAGLLEVQASLQPGRISRIAINREEQVLGWIGGLPRYAGHVWEL
HPLVVKASERGQGWGRRLVADLETCVQQRGGLTLWVGTDDETGQTNLSHANLYPNVLEHLAQLQNLHQHPYEFYQKCGFS
VVGVMPDANGRGKPDIYMAKAITPKP
>Mature_185_residues
PILDLPPDHPQIHRDVATLLVDGFRENWPEAWPHLEAGLLEVQASLQPGRISRIAINREEQVLGWIGGLPRYAGHVWELH
PLVVKASERGQGWGRRLVADLETCVQQRGGLTLWVGTDDETGQTNLSHANLYPNVLEHLAQLQNLHQHPYEFYQKCGFSV
VGVMPDANGRGKPDIYMAKAITPKP

Specific function: Resistance to antibiotics containing the purpurosamine ring including gentamicin, kanamycin, tobramycin, and neomycin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.82 [H]

Molecular weight: Translated: 20841; Mature: 20710

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILDLPPDHPQIHRDVATLLVDGFRENWPEAWPHLEAGLLEVQASLQPGRISRIAINRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCH
EQVLGWIGGLPRYAGHVWELHPLVVKASERGQGWGRRLVADLETCVQQRGGLTLWVGTDD
HHHHHHHCCCHHHHCCCEEECEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
ETGQTNLSHANLYPNVLEHLAQLQNLHQHPYEFYQKCGFSVVGVMPDANGRGKPDIYMAK
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEE
AITPKP
CCCCCC
>Mature Secondary Structure 
PILDLPPDHPQIHRDVATLLVDGFRENWPEAWPHLEAGLLEVQASLQPGRISRIAINRE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCH
EQVLGWIGGLPRYAGHVWELHPLVVKASERGQGWGRRLVADLETCVQQRGGLTLWVGTDD
HHHHHHHCCCHHHHCCCEEECEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
ETGQTNLSHANLYPNVLEHLAQLQNLHQHPYEFYQKCGFSVVGVMPDANGRGKPDIYMAK
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEE
AITPKP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2826403 [H]