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The map label for this gene is phoP [H]

Identifier: 158337064

GI number: 158337064

Start: 3986756

End: 3987847

Strand: Reverse

Name: phoP [H]

Synonym: AM1_3937

Alternate gene names: 158337064

Gene position: 3987847-3986756 (Counterclockwise)

Preceding gene: 158337065

Following gene: 158337063

Centisome position: 61.32

GC content: 39.65

Gene sequence:

>1092_bases
ATGTCCAAAGTTCTTGTCATTGAAGATCAAGATGACATTCGCAGTATTGTTTGCGAAATACTAATTGCTGAAAGCTTCAA
TGTAATCGAAGCGGAAGACGGTCACATCGGCGTTTTACTAGCTCAGGAAGAAATGCCAGATCTAGTGATTTGTGACATTA
TGATGCCTGAATTTGATGGCTATAGCGTCATGACCCAACTTCGACAAAATCCTTATTTGCAGTCCGTTCCGTTTATCTTT
TTAACAGCAAAAGCCAGTAAGACCGATCTGAGATTAGGGATGGAGCTAGGCGCCAATGATTATTTAACCAAACCCTTTAC
ACGAGATGAACTATTAGGAGCAGTCAATGCTCAAATAGAGACCGTATCAACTCATCAATCTGATGATCAGCCCATTTGGA
AAGATCGCTGCTGCGATCTCATTCAATCTCTTCCCGTAGAAATACATCAACCTCTACAACAAATTCTCAAGCTTTCACAG
TCCTTGCTAGAGGAAGAATGCCAGAATAGTGCTCCTGCTCAGAATATCTTGAATGAGATCAAGGGTACGGGAGGTTTATT
ATACAAACGGCTCCAAAATATTTTCATTTATCAAGAATTAGCAAGTATAGAACAAAATTCTCAACGCCTAAGAGTATTTA
GAAAGAATCCGGGTGTTTGTGACACAAAAGCGGTTATTGCTAATATTGCTCGTTCTCAAGCTCAATACTATAGCCGCATC
TCTGATTTACAGTTGGAATTAGAAGACGCAACTGTACTACTCGCACAGCCAAAATTACAAAAAATCATAGAAGAAATTGT
TGATAATTCATTTAAATATTCCTCTTTAGGAACTTCTGTACGCCTTAAGAGTTCCGTGCATGGTCATACTTTCTTGTTTC
AGATTATGAACGAAGGGCAAGGTCCTAGCCCTAATCAGCTACAAGCGCTGGGATCTCACATGCAATTTGACCATGCGTCT
TATCTACATACGTGTGTTGGCTTGGGGTTGATTATTGCCAAGCTAATTGCTGAACTCCATGGTGGTGAGTTGCAAGTCAA
ATGTGAGCAAGAGAAATATACAAAAGTGTCAATATTTTTGCCTTTAGCCTAA

Upstream 100 bases:

>100_bases
ATTAAATAAAAGTCATTTATGCATCTATTGATTCGTCTTTAGAAATGCTCGTTTGAGTCCCTCCATAAGGGATTTGTGAT
TTTCACAACATATCATCACC

Downstream 100 bases:

>100_bases
AAACTGAACCTATTTCAAACTATTGACAATGGTCAATCTGTCTATTGTAATTTACTAGCTTAATTATTCGAATTCTTCAA
TAGATTCAAGATCGTGTAAG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSKVLVIEDQDDIRSIVCEILIAESFNVIEAEDGHIGVLLAQEEMPDLVICDIMMPEFDGYSVMTQLRQNPYLQSVPFIF
LTAKASKTDLRLGMELGANDYLTKPFTRDELLGAVNAQIETVSTHQSDDQPIWKDRCCDLIQSLPVEIHQPLQQILKLSQ
SLLEEECQNSAPAQNILNEIKGTGGLLYKRLQNIFIYQELASIEQNSQRLRVFRKNPGVCDTKAVIANIARSQAQYYSRI
SDLQLELEDATVLLAQPKLQKIIEEIVDNSFKYSSLGTSVRLKSSVHGHTFLFQIMNEGQGPSPNQLQALGSHMQFDHAS
YLHTCVGLGLIIAKLIAELHGGELQVKCEQEKYTKVSIFLPLA

Sequences:

>Translated_363_residues
MSKVLVIEDQDDIRSIVCEILIAESFNVIEAEDGHIGVLLAQEEMPDLVICDIMMPEFDGYSVMTQLRQNPYLQSVPFIF
LTAKASKTDLRLGMELGANDYLTKPFTRDELLGAVNAQIETVSTHQSDDQPIWKDRCCDLIQSLPVEIHQPLQQILKLSQ
SLLEEECQNSAPAQNILNEIKGTGGLLYKRLQNIFIYQELASIEQNSQRLRVFRKNPGVCDTKAVIANIARSQAQYYSRI
SDLQLELEDATVLLAQPKLQKIIEEIVDNSFKYSSLGTSVRLKSSVHGHTFLFQIMNEGQGPSPNQLQALGSHMQFDHAS
YLHTCVGLGLIIAKLIAELHGGELQVKCEQEKYTKVSIFLPLA
>Mature_362_residues
SKVLVIEDQDDIRSIVCEILIAESFNVIEAEDGHIGVLLAQEEMPDLVICDIMMPEFDGYSVMTQLRQNPYLQSVPFIFL
TAKASKTDLRLGMELGANDYLTKPFTRDELLGAVNAQIETVSTHQSDDQPIWKDRCCDLIQSLPVEIHQPLQQILKLSQS
LLEEECQNSAPAQNILNEIKGTGGLLYKRLQNIFIYQELASIEQNSQRLRVFRKNPGVCDTKAVIANIARSQAQYYSRIS
DLQLELEDATVLLAQPKLQKIIEEIVDNSFKYSSLGTSVRLKSSVHGHTFLFQIMNEGQGPSPNQLQALGSHMQFDHASY
LHTCVGLGLIIAKLIAELHGGELQVKCEQEKYTKVSIFLPLA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=35.5371900826446, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=28.7610619469027, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367329, Length=130, Percent_Identity=39.2307692307692, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=38.135593220339, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789809, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790860, Length=125, Percent_Identity=31.2, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786784, Length=115, Percent_Identity=35.6521739130435, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=30.6306306306306, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=115, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787375, Length=115, Percent_Identity=33.0434782608696, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788191, Length=106, Percent_Identity=34.9056603773585, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 40704; Mature: 40573

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLVIEDQDDIRSIVCEILIAESFNVIEAEDGHIGVLLAQEEMPDLVICDIMMPEFDG
CCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEEEEECCCCCC
YSVMTQLRQNPYLQSVPFIFLTAKASKTDLRLGMELGANDYLTKPFTRDELLGAVNAQIE
HHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCEEE
TVSTHQSDDQPIWKDRCCDLIQSLPVEIHQPLQQILKLSQSLLEEECQNSAPAQNILNEI
EEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KGTGGLLYKRLQNIFIYQELASIEQNSQRLRVFRKNPGVCDTKAVIANIARSQAQYYSRI
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SDLQLELEDATVLLAQPKLQKIIEEIVDNSFKYSSLGTSVRLKSSVHGHTFLFQIMNEGQ
HHHEEEECCCEEEEECHHHHHHHHHHHCCCCEECCCCCCEEEECCCCCHHHHHHHHHCCC
GPSPNQLQALGSHMQFDHASYLHTCVGLGLIIAKLIAELHGGELQVKCEQEKYTKVSIFL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEE
PLA
ECC
>Mature Secondary Structure 
SKVLVIEDQDDIRSIVCEILIAESFNVIEAEDGHIGVLLAQEEMPDLVICDIMMPEFDG
CCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEEEEECCCCCC
YSVMTQLRQNPYLQSVPFIFLTAKASKTDLRLGMELGANDYLTKPFTRDELLGAVNAQIE
HHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCEEE
TVSTHQSDDQPIWKDRCCDLIQSLPVEIHQPLQQILKLSQSLLEEECQNSAPAQNILNEI
EEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KGTGGLLYKRLQNIFIYQELASIEQNSQRLRVFRKNPGVCDTKAVIANIARSQAQYYSRI
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SDLQLELEDATVLLAQPKLQKIIEEIVDNSFKYSSLGTSVRLKSSVHGHTFLFQIMNEGQ
HHHEEEECCCEEEEECHHHHHHHHHHHCCCCEECCCCCCEEEECCCCCHHHHHHHHHCCC
GPSPNQLQALGSHMQFDHASYLHTCVGLGLIIAKLIAELHGGELQVKCEQEKYTKVSIFL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEE
PLA
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]