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The map label for this gene is aphA [H]

Identifier: 158336997

GI number: 158336997

Start: 3923040

End: 3924227

Strand: Reverse

Name: aphA [H]

Synonym: AM1_3870

Alternate gene names: 158336997

Gene position: 3924227-3923040 (Counterclockwise)

Preceding gene: 158336998

Following gene: 158336996

Centisome position: 60.34

GC content: 46.55

Gene sequence:

>1188_bases
GTGTTGCTTCTGCTGGCAGGAGGCAGTGTGTTCATTTGGAAGTTGCAGCAATCCGCTGACCGTCAACAAGACCGATATTT
TCAAATGATGGCCAACCCGTCTCCTGCTCCCATGTGGGTCGCGGATGCAGACAGGATGTTCTCATTTTTTAACCAAACTT
GGTTAACCACGACGGGACGAACGATGGCAGCTGAGATCGGTTATGGATGGATGTCAGGCATTCATCCTGACGATCGACAA
CGATGGCAGAAAACCTATGAGTCGAGCTTTAACCAACAGCAAGAATTTGCGATCGAGCATCGACTGCGCCAGCGGGATGG
TAGCTATGCCTGGATGCTTTCCCTGGGAAAACCTAGATATACCCAGGATGAAACATTTTGTGGATATGTTGGCACCACGA
TGGATATCACTGCCCTGAAACAAGCAGATGCTCAATGTCAAATGGTCAATACAGAGCTATTGCGGTCCAACCAAGAATTA
GAGCAGATGGCTTCAGTCCTCTCTCACGATATGCGCGAGCCCTTGCGTAAAATCCAATCTTTTGCGGAGCTAGTGCAAGC
AGACTATGTCGATAACATTGATGAACAAGGACAACGGTATTTTGAGTATGTGATTGACGGAGCAGAGCGAATGCAGGCCA
TGATTACTGATTTGCTCGCCTATGCCCGGTTATCGTCCGAAGACCGAGAGGTCACTTTAACCAATTTGGGAACAGTGTTA
GAGCAAGTCCAGCAAGATTTAAGCCTGACTATTGCTGAAAGTGAAGCTGTGATTGAAGTAGGCGACTTACCTGTAATGAT
GATCAATCCGACGGATATGCAGCGGGTATTTCAGAATTTATTGTCTAATGCCTTAAAGTTTCGAGGAGAGGCCGTTCCCC
ATATTCAGATCTCAGCTAGCAAACTCCACAAACATTGGTTAATCACGGTTGAAGACAATGGTATCGGTATCTCAGAGGAT
GCTGTAGAAGATATTTTTGTGATGTTCAAGCGCTTGCACAATCGCACAGACTACGACGGCACGGGTATCGGCTTGGCGAT
TTGCAAGAAAATTATTGACCATTATGATGGTTCGATCTGGGCTGAGTCGAAGCTAGGGGAGGGGACCACGTTCCATATCA
AACTCCCTAGCCATTTCCAAGATCATTGGACAACGGACCAACCTTTTGTAAGTGTATTCGATTTTTAA

Upstream 100 bases:

>100_bases
TGCAGTACAGGGGAGAAATTGGGTTGTGGTCACTCAGGTCACCCCTCAATTTATTCAGCAACACACCAGCGGGTTATGGG
TCTTTCTACCTTTTGTGGGG

Downstream 100 bases:

>100_bases
AACGTCTACCTATGGGTTGATATTGGAGCAGCAGAAGACTCGAAAATATCACAAATTATCAAGGAGACATGAGGGAGAAT
CGCAGGTTGGGCATACTGCC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLLLLAGGSVFIWKLQQSADRQQDRYFQMMANPSPAPMWVADADRMFSFFNQTWLTTTGRTMAAEIGYGWMSGIHPDDRQ
RWQKTYESSFNQQQEFAIEHRLRQRDGSYAWMLSLGKPRYTQDETFCGYVGTTMDITALKQADAQCQMVNTELLRSNQEL
EQMASVLSHDMREPLRKIQSFAELVQADYVDNIDEQGQRYFEYVIDGAERMQAMITDLLAYARLSSEDREVTLTNLGTVL
EQVQQDLSLTIAESEAVIEVGDLPVMMINPTDMQRVFQNLLSNALKFRGEAVPHIQISASKLHKHWLITVEDNGIGISED
AVEDIFVMFKRLHNRTDYDGTGIGLAICKKIIDHYDGSIWAESKLGEGTTFHIKLPSHFQDHWTTDQPFVSVFDF

Sequences:

>Translated_395_residues
MLLLLAGGSVFIWKLQQSADRQQDRYFQMMANPSPAPMWVADADRMFSFFNQTWLTTTGRTMAAEIGYGWMSGIHPDDRQ
RWQKTYESSFNQQQEFAIEHRLRQRDGSYAWMLSLGKPRYTQDETFCGYVGTTMDITALKQADAQCQMVNTELLRSNQEL
EQMASVLSHDMREPLRKIQSFAELVQADYVDNIDEQGQRYFEYVIDGAERMQAMITDLLAYARLSSEDREVTLTNLGTVL
EQVQQDLSLTIAESEAVIEVGDLPVMMINPTDMQRVFQNLLSNALKFRGEAVPHIQISASKLHKHWLITVEDNGIGISED
AVEDIFVMFKRLHNRTDYDGTGIGLAICKKIIDHYDGSIWAESKLGEGTTFHIKLPSHFQDHWTTDQPFVSVFDF
>Mature_395_residues
MLLLLAGGSVFIWKLQQSADRQQDRYFQMMANPSPAPMWVADADRMFSFFNQTWLTTTGRTMAAEIGYGWMSGIHPDDRQ
RWQKTYESSFNQQQEFAIEHRLRQRDGSYAWMLSLGKPRYTQDETFCGYVGTTMDITALKQADAQCQMVNTELLRSNQEL
EQMASVLSHDMREPLRKIQSFAELVQADYVDNIDEQGQRYFEYVIDGAERMQAMITDLLAYARLSSEDREVTLTNLGTVL
EQVQQDLSLTIAESEAVIEVGDLPVMMINPTDMQRVFQNLLSNALKFRGEAVPHIQISASKLHKHWLITVEDNGIGISED
AVEDIFVMFKRLHNRTDYDGTGIGLAICKKIIDHYDGSIWAESKLGEGTTFHIKLPSHFQDHWTTDQPFVSVFDF

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=292, Percent_Identity=23.6301369863014, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=266, Percent_Identity=28.1954887218045, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=377, Percent_Identity=23.342175066313, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=25.968992248062, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=26.6375545851528, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=25.1046025104602, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=264, Percent_Identity=22.3484848484848, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=27.0491803278689, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=320, Percent_Identity=26.5625, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=267, Percent_Identity=24.3445692883895, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45317; Mature: 45317

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLAGGSVFIWKLQQSADRQQDRYFQMMANPSPAPMWVADADRMFSFFNQTWLTTTGR
CEEEEECCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHEEECCC
TMAAEIGYGWMSGIHPDDRQRWQKTYESSFNQQQEFAIEHRLRQRDGSYAWMLSLGKPRY
HHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TQDETFCGYVGTTMDITALKQADAQCQMVNTELLRSNQELEQMASVLSHDMREPLRKIQS
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FAELVQADYVDNIDEQGQRYFEYVIDGAERMQAMITDLLAYARLSSEDREVTLTNLGTVL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
EQVQQDLSLTIAESEAVIEVGDLPVMMINPTDMQRVFQNLLSNALKFRGEAVPHIQISAS
HHHHHHHEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
KLHKHWLITVEDNGIGISEDAVEDIFVMFKRLHNRTDYDGTGIGLAICKKIIDHYDGSIW
HHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEE
AESKLGEGTTFHIKLPSHFQDHWTTDQPFVSVFDF
ECCCCCCCCEEEEECCCCHHHCCCCCCCCCEECCC
>Mature Secondary Structure
MLLLLAGGSVFIWKLQQSADRQQDRYFQMMANPSPAPMWVADADRMFSFFNQTWLTTTGR
CEEEEECCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHEEECCC
TMAAEIGYGWMSGIHPDDRQRWQKTYESSFNQQQEFAIEHRLRQRDGSYAWMLSLGKPRY
HHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TQDETFCGYVGTTMDITALKQADAQCQMVNTELLRSNQELEQMASVLSHDMREPLRKIQS
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FAELVQADYVDNIDEQGQRYFEYVIDGAERMQAMITDLLAYARLSSEDREVTLTNLGTVL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
EQVQQDLSLTIAESEAVIEVGDLPVMMINPTDMQRVFQNLLSNALKFRGEAVPHIQISAS
HHHHHHHEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
KLHKHWLITVEDNGIGISEDAVEDIFVMFKRLHNRTDYDGTGIGLAICKKIIDHYDGSIW
HHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEE
AESKLGEGTTFHIKLPSHFQDHWTTDQPFVSVFDF
ECCCCCCCCEEEEECCCCHHHCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]