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The map label for this gene is pmi [H]

Identifier: 158336969

GI number: 158336969

Start: 3895562

End: 3896743

Strand: Reverse

Name: pmi [H]

Synonym: AM1_3842

Alternate gene names: 158336969

Gene position: 3896743-3895562 (Counterclockwise)

Preceding gene: 158336970

Following gene: 158336968

Centisome position: 59.92

GC content: 48.48

Gene sequence:

>1182_bases
ATGAACCTGACGTTTGCAGAACTGGCCTTACAGTACAAACAAGCGCTGTTAGACGATGTCCTCCCTTTTTGGCAAAACTA
TTCTTTAGATGAGCAGGAAGGGGGCTACTTTACCTGCTTAGATACCCAAGGTCAGGTCTACGACACGGACAAATTTATTT
GGCTGCAAAACCGCCAAGTCTGGACCTTCTCCATGCTCTATAATCAGCTCTCTCCAGACCCTGACTGGCTAGAAGTGGCC
CGATTGGGGGCTGATTTTCTGGCTAATAAAGGACGAGATGCAGACGGTAACTGGTACTTTGCTTTGAATCGGGCTGGGGC
GCCTTTAGTGCAGCCCTACAATATCTTCTCGGATTGCTTTGCGGCGATGGCTTTTAGCCAATTTGCGGTAGCTTCCCAGG
AAGACGCTGCAAAAGCTGTAGCCCTCCAAGCCTATAACAATGTTCTGCGCCGACAACAAGATCCGAAAGGACGGTATAAC
AAACTCTATCCTGGGACACGTCCCTTAAAATCCCTTGCAGTTCCCATGATTTTGGCAAACTTAACCCTAGAAATGGTACC
CCTGTTCGATTCCGCTCAGCTGGATCAGGTCTTGGATCAGACGGTGCAAGAGGTGATGACCGATTTTCTGGATACAGAAC
GAGGGCTATTATTTGAAGCTGTGGCTCCAGCGGGTGACCAGGTCGATTGTTTTGAAGGTCGATTAATTAATCCTGGTCAT
GGCATTGAGGCCATGTGGTTTTTGATGGATATTGGCCAGCGCCGCCATGATAAAGCGTTAATTGAACGGGCCGTTGATGT
GGTCCTGAATATCTTAGACTTTAGCTGGGACCAGGAGTATGGCGGCTTGTTCTACTTCCTAGATGCAGCAGGACATCCTC
CCCAGCAATTGGAATGGGACCAAAAGTTATGGTGGGTTCATCTGGAAACATTAGTGGCCTTAGTCATGGGGTACCGCTTG
ACGGGTCGAGAAGAATGCTGGCAATGGTATCAAAAGGTGCATGACTATAGCTGGTCCCATTTTGCTGATCCGGGTCGAGA
ATGGTTTGGCTATTTAAATCGAGCCGGACAAGTCCATTTACAGCTTAAAGGCGGCAAGTGGAAGGGCTGCTTCCATGTAC
CTAGAGCTTTGTTTCTCTGCTGGCAACAGTTTGAAAAGCTGAGTGCCAAAAACTTGGCATGA

Upstream 100 bases:

>100_bases
ATCCGATGCAGAATCGACTCCCAGCTCTACCTAAGCCGTTGGTCTTGAACGAAAAGTAACAACTCCACTGATAACCACTC
ATTGATCATCGGGAGAAGGG

Downstream 100 bases:

>100_bases
AGTTTGAGCTGGCTATTTTTGACTGTGATGGGGTGCTGATTGATAGTGAACTGCTGGCTAATCGTATAGATGTAGAGTGC
TTACAGGCGTTAGGGATTGA

Product: N-acylglucosamine 2-epimerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNLTFAELALQYKQALLDDVLPFWQNYSLDEQEGGYFTCLDTQGQVYDTDKFIWLQNRQVWTFSMLYNQLSPDPDWLEVA
RLGADFLANKGRDADGNWYFALNRAGAPLVQPYNIFSDCFAAMAFSQFAVASQEDAAKAVALQAYNNVLRRQQDPKGRYN
KLYPGTRPLKSLAVPMILANLTLEMVPLFDSAQLDQVLDQTVQEVMTDFLDTERGLLFEAVAPAGDQVDCFEGRLINPGH
GIEAMWFLMDIGQRRHDKALIERAVDVVLNILDFSWDQEYGGLFYFLDAAGHPPQQLEWDQKLWWVHLETLVALVMGYRL
TGREECWQWYQKVHDYSWSHFADPGREWFGYLNRAGQVHLQLKGGKWKGCFHVPRALFLCWQQFEKLSAKNLA

Sequences:

>Translated_393_residues
MNLTFAELALQYKQALLDDVLPFWQNYSLDEQEGGYFTCLDTQGQVYDTDKFIWLQNRQVWTFSMLYNQLSPDPDWLEVA
RLGADFLANKGRDADGNWYFALNRAGAPLVQPYNIFSDCFAAMAFSQFAVASQEDAAKAVALQAYNNVLRRQQDPKGRYN
KLYPGTRPLKSLAVPMILANLTLEMVPLFDSAQLDQVLDQTVQEVMTDFLDTERGLLFEAVAPAGDQVDCFEGRLINPGH
GIEAMWFLMDIGQRRHDKALIERAVDVVLNILDFSWDQEYGGLFYFLDAAGHPPQQLEWDQKLWWVHLETLVALVMGYRL
TGREECWQWYQKVHDYSWSHFADPGREWFGYLNRAGQVHLQLKGGKWKGCFHVPRALFLCWQQFEKLSAKNLA
>Mature_393_residues
MNLTFAELALQYKQALLDDVLPFWQNYSLDEQEGGYFTCLDTQGQVYDTDKFIWLQNRQVWTFSMLYNQLSPDPDWLEVA
RLGADFLANKGRDADGNWYFALNRAGAPLVQPYNIFSDCFAAMAFSQFAVASQEDAAKAVALQAYNNVLRRQQDPKGRYN
KLYPGTRPLKSLAVPMILANLTLEMVPLFDSAQLDQVLDQTVQEVMTDFLDTERGLLFEAVAPAGDQVDCFEGRLINPGH
GIEAMWFLMDIGQRRHDKALIERAVDVVLNILDFSWDQEYGGLFYFLDAAGHPPQQLEWDQKLWWVHLETLVALVMGYRL
TGREECWQWYQKVHDYSWSHFADPGREWFGYLNRAGQVHLQLKGGKWKGCFHVPRALFLCWQQFEKLSAKNLA

Specific function: Unknown

COG id: COG2942

COG function: function code G; N-acyl-D-glucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acylglucosamine 2-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI213417820, Length=384, Percent_Identity=35.9375, Blast_Score=230, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819 [H]

Pfam domain/function: PF07221 GlcNAc_2-epim [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 45343; Mature: 45343

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTFAELALQYKQALLDDVLPFWQNYSLDEQEGGYFTCLDTQGQVYDTDKFIWLQNRQV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECCCEEEEECCCE
WTFSMLYNQLSPDPDWLEVARLGADFLANKGRDADGNWYFALNRAGAPLVQPYNIFSDCF
EEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAMAFSQFAVASQEDAAKAVALQAYNNVLRRQQDPKGRYNKLYPGTRPLKSLAVPMILAN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LTLEMVPLFDSAQLDQVLDQTVQEVMTDFLDTERGLLFEAVAPAGDQVDCFEGRLINPGH
HHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCC
GIEAMWFLMDIGQRRHDKALIERAVDVVLNILDFSWDQEYGGLFYFLDAAGHPPQQLEWD
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCCCC
QKLWWVHLETLVALVMGYRLTGREECWQWYQKVHDYSWSHFADPGREWFGYLNRAGQVHL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
QLKGGKWKGCFHVPRALFLCWQQFEKLSAKNLA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLTFAELALQYKQALLDDVLPFWQNYSLDEQEGGYFTCLDTQGQVYDTDKFIWLQNRQV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECCCEEEEECCCE
WTFSMLYNQLSPDPDWLEVARLGADFLANKGRDADGNWYFALNRAGAPLVQPYNIFSDCF
EEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAMAFSQFAVASQEDAAKAVALQAYNNVLRRQQDPKGRYNKLYPGTRPLKSLAVPMILAN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LTLEMVPLFDSAQLDQVLDQTVQEVMTDFLDTERGLLFEAVAPAGDQVDCFEGRLINPGH
HHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCC
GIEAMWFLMDIGQRRHDKALIERAVDVVLNILDFSWDQEYGGLFYFLDAAGHPPQQLEWD
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCCCC
QKLWWVHLETLVALVMGYRLTGREECWQWYQKVHDYSWSHFADPGREWFGYLNRAGQVHL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
QLKGGKWKGCFHVPRALFLCWQQFEKLSAKNLA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1452036; 11481430 [H]