Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 158336869

GI number: 158336869

Start: 3789602

End: 3791227

Strand: Direct

Name: pkn1 [H]

Synonym: AM1_3737

Alternate gene names: 158336869

Gene position: 3789602-3791227 (Clockwise)

Preceding gene: 158336868

Following gene: 158336870

Centisome position: 58.27

GC content: 53.87

Gene sequence:

>1626_bases
TTGGCAATCGGTATGGGAATGCAGCGCAGACAGTTTTTACGCTTTGGGGGCACAGTCTTGCTGACCCTCGTGGCTTCTCC
CAGGTCCTTCGCGAAATCCGTTGATGACATTCGCAAAATCGCCCGACAGATCACCGTCAAAATCCTGACTCAAGGGCCGT
CTGGGTCGGGGATCTTGATTCAGAAAAAGGGGCCTATCTATACGGTGCTGACAGCCGCCCATGTGATCAAAAATTCAAAT
CGTGGGGAAGAAGCCTATGCCATGACGAGTGATGGTGAGAATCACTTGCTGGATACCCAAGCCATGAAGACTGGCTCTAA
CTTAGATCTTGCGATCGCAACCTTCTACAGCAATAAAACCTATGGCGTGACTGATGTCGGTCAATTTAAAGCCCTCGATA
TTTTGGATGAAATCTATGTGGGAGGGTATCCCTTAGCGGATCAAGGTATATCCGTCTCGACGATCACGCTGACTCGGGGA
GAGGTCGCTTCGATTGGCCCCTTTGAGGATGGCTATGGGTTTTCCTATACTGCGGTAACCAAAGCGGGGATGAGTGGTGG
TCCCATCCTCAATCAGGCGGGCCAGCTTATCGGCGTTCATGGTCGAGCAGCAGGACAGCGATTGAAACAGTTTCGGCTCA
AGGACGGCCTGAATTTGGGGATTCCCATCGACACCGCCATCGAGGTATTTGGGTTGAAGACCCTCGCCCCAACGGTGGCG
CAACCTGACGAACCGGAGCCTCAATCGGCTGAGACGGATCCGCCAGAGGAAGAGCCTTCCAGTCCTTCACCAGATTCCCC
TTTGGTGAGCTTCACCTTTGAAGTGCTGGGGGTCAATGACAAAGGCCAGGTGCGTAAACGGATGCAACAGTCGGCCCAAT
CTTATCGCCAACCCCTGGTGGGTGGAGTGGCCTTGGAGATGGTGGCTATTCCCGGGGGACAGTTCACGATGGGCTCGCCA
GTAACCGAAACCCATCGTGAGAAAAACGAAGATCCGAAACATGTTGTGGATGTCCCGGCGTTTTTGATGGGGAAGTATCC
CATTACCCAAGCCCAGTGGCAGGCCATTATGGGGGACAATCCCTCTAAGTTTCAGGGGGCCAATCATCCCGTCGATCAAG
TTAGCTGGTTTTTAGCGGAAGAGTTTTGCCAGAAACTGTCTTTGGCGACGGGGCAAGACTATCGGCTGCCCAGTGAAGCC
GAATGGGAATATGCCGCCCGAGCGGGTACCGATACCCCGTTTCACTTCGGTCAGACCATCACCACCGATCTGGCCAATTA
TGATGGCAATTACGCCTATGACAAAGGCCCCAAGGGCACCTTCAGAAAAAAGACGGTTCCGGTGGACCAGTTGGCCGGGA
ATGCCTTTGGGTTGTTCAATATGCATGGTCAGGTTTGGGAATGGTGTCTAGACCATTGGCATGACACCTATGACGGTGCG
CCTAGGGATGGTACGGCCTGGGTTGAGCAGGGTGACCCAAAAATGCGCCGAGTGCGGCGAGGCGGATCCTGGTATGACAG
TCCCCATGCCTGCCGATCTGCATTTCGCTACCGATCCTATCCCTATGCCTATACGGGGTCTTTTGGTTTGCGCGTGGTTC
TGCCTGCCCTAAATCAAACGGTGTAG

Upstream 100 bases:

>100_bases
TCAAGAAAGACAACGGCAGCGTCAGGGCTCACCCTTGTGAGTTGATCAAGCAAACCGTTTAGGGTACTTGCCCTGAGAGA
AGTGATGGAGAAACAGGCAT

Downstream 100 bases:

>100_bases
AGGACTGGCTTTGGGGAGAGAATGCGCTAATATCCGTATCACCCTTCTAATCCGAGACATTCCCAAATAGAGCGGATACA
GTAGGAATAAGGGTTTTGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MAIGMGMQRRQFLRFGGTVLLTLVASPRSFAKSVDDIRKIARQITVKILTQGPSGSGILIQKKGPIYTVLTAAHVIKNSN
RGEEAYAMTSDGENHLLDTQAMKTGSNLDLAIATFYSNKTYGVTDVGQFKALDILDEIYVGGYPLADQGISVSTITLTRG
EVASIGPFEDGYGFSYTAVTKAGMSGGPILNQAGQLIGVHGRAAGQRLKQFRLKDGLNLGIPIDTAIEVFGLKTLAPTVA
QPDEPEPQSAETDPPEEEPSSPSPDSPLVSFTFEVLGVNDKGQVRKRMQQSAQSYRQPLVGGVALEMVAIPGGQFTMGSP
VTETHREKNEDPKHVVDVPAFLMGKYPITQAQWQAIMGDNPSKFQGANHPVDQVSWFLAEEFCQKLSLATGQDYRLPSEA
EWEYAARAGTDTPFHFGQTITTDLANYDGNYAYDKGPKGTFRKKTVPVDQLAGNAFGLFNMHGQVWEWCLDHWHDTYDGA
PRDGTAWVEQGDPKMRRVRRGGSWYDSPHACRSAFRYRSYPYAYTGSFGLRVVLPALNQTV

Sequences:

>Translated_541_residues
MAIGMGMQRRQFLRFGGTVLLTLVASPRSFAKSVDDIRKIARQITVKILTQGPSGSGILIQKKGPIYTVLTAAHVIKNSN
RGEEAYAMTSDGENHLLDTQAMKTGSNLDLAIATFYSNKTYGVTDVGQFKALDILDEIYVGGYPLADQGISVSTITLTRG
EVASIGPFEDGYGFSYTAVTKAGMSGGPILNQAGQLIGVHGRAAGQRLKQFRLKDGLNLGIPIDTAIEVFGLKTLAPTVA
QPDEPEPQSAETDPPEEEPSSPSPDSPLVSFTFEVLGVNDKGQVRKRMQQSAQSYRQPLVGGVALEMVAIPGGQFTMGSP
VTETHREKNEDPKHVVDVPAFLMGKYPITQAQWQAIMGDNPSKFQGANHPVDQVSWFLAEEFCQKLSLATGQDYRLPSEA
EWEYAARAGTDTPFHFGQTITTDLANYDGNYAYDKGPKGTFRKKTVPVDQLAGNAFGLFNMHGQVWEWCLDHWHDTYDGA
PRDGTAWVEQGDPKMRRVRRGGSWYDSPHACRSAFRYRSYPYAYTGSFGLRVVLPALNQTV
>Mature_540_residues
AIGMGMQRRQFLRFGGTVLLTLVASPRSFAKSVDDIRKIARQITVKILTQGPSGSGILIQKKGPIYTVLTAAHVIKNSNR
GEEAYAMTSDGENHLLDTQAMKTGSNLDLAIATFYSNKTYGVTDVGQFKALDILDEIYVGGYPLADQGISVSTITLTRGE
VASIGPFEDGYGFSYTAVTKAGMSGGPILNQAGQLIGVHGRAAGQRLKQFRLKDGLNLGIPIDTAIEVFGLKTLAPTVAQ
PDEPEPQSAETDPPEEEPSSPSPDSPLVSFTFEVLGVNDKGQVRKRMQQSAQSYRQPLVGGVALEMVAIPGGQFTMGSPV
TETHREKNEDPKHVVDVPAFLMGKYPITQAQWQAIMGDNPSKFQGANHPVDQVSWFLAEEFCQKLSLATGQDYRLPSEAE
WEYAARAGTDTPFHFGQTITTDLANYDGNYAYDKGPKGTFRKKTVPVDQLAGNAFGLFNMHGQVWEWCLDHWHDTYDGAP
RDGTAWVEQGDPKMRRVRRGGSWYDSPHACRSAFRYRSYPYAYTGSFGLRVVLPALNQTV

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=274, Percent_Identity=27.7372262773723, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38202250, Length=299, Percent_Identity=25.4180602006689, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI257470977, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130397, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 59194; Mature: 59063

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGMGMQRRQFLRFGGTVLLTLVASPRSFAKSVDDIRKIARQITVKILTQGPSGSGILI
CCCCCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEE
QKKGPIYTVLTAAHVIKNSNRGEEAYAMTSDGENHLLDTQAMKTGSNLDLAIATFYSNKT
ECCCCEEEHHHHHHHHHCCCCCCCEEEECCCCCCCEECHHHHHCCCCCEEEEEEEECCCC
YGVTDVGQFKALDILDEIYVGGYPLADQGISVSTITLTRGEVASIGPFEDGYGFSYTAVT
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEHHHH
KAGMSGGPILNQAGQLIGVHGRAAGQRLKQFRLKDGLNLGIPIDTAIEVFGLKTLAPTVA
HCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
QPDEPEPQSAETDPPEEEPSSPSPDSPLVSFTFEVLGVNDKGQVRKRMQQSAQSYRQPLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GGVALEMVAIPGGQFTMGSPVTETHREKNEDPKHVVDVPAFLMGKYPITQAQWQAIMGDN
CCEEEEEEEECCCCEECCCCCHHHHHHCCCCCCHHHHCCHHHHCCCCCCHHHHHHHHCCC
PSKFQGANHPVDQVSWFLAEEFCQKLSLATGQDYRLPSEAEWEYAARAGTDTPFHFGQTI
CHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHH
TTDLANYDGNYAYDKGPKGTFRKKTVPVDQLAGNAFGLFNMHGQVWEWCLDHWHDTYDGA
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCC
PRDGTAWVEQGDPKMRRVRRGGSWYDSPHACRSAFRYRSYPYAYTGSFGLRVVLPALNQT
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCEEEEECHHCCC
V
C
>Mature Secondary Structure 
AIGMGMQRRQFLRFGGTVLLTLVASPRSFAKSVDDIRKIARQITVKILTQGPSGSGILI
CCCCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEE
QKKGPIYTVLTAAHVIKNSNRGEEAYAMTSDGENHLLDTQAMKTGSNLDLAIATFYSNKT
ECCCCEEEHHHHHHHHHCCCCCCCEEEECCCCCCCEECHHHHHCCCCCEEEEEEEECCCC
YGVTDVGQFKALDILDEIYVGGYPLADQGISVSTITLTRGEVASIGPFEDGYGFSYTAVT
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEHHHH
KAGMSGGPILNQAGQLIGVHGRAAGQRLKQFRLKDGLNLGIPIDTAIEVFGLKTLAPTVA
HCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
QPDEPEPQSAETDPPEEEPSSPSPDSPLVSFTFEVLGVNDKGQVRKRMQQSAQSYRQPLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GGVALEMVAIPGGQFTMGSPVTETHREKNEDPKHVVDVPAFLMGKYPITQAQWQAIMGDN
CCEEEEEEEECCCCEECCCCCHHHHHHCCCCCCHHHHCCHHHHCCCCCCHHHHHHHHCCC
PSKFQGANHPVDQVSWFLAEEFCQKLSLATGQDYRLPSEAEWEYAARAGTDTPFHFGQTI
CHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHH
TTDLANYDGNYAYDKGPKGTFRKKTVPVDQLAGNAFGLFNMHGQVWEWCLDHWHDTYDGA
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCC
PRDGTAWVEQGDPKMRRVRRGGSWYDSPHACRSAFRYRSYPYAYTGSFGLRVVLPALNQT
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCEEEEECHHCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]