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The map label for this gene is suhB [H]

Identifier: 158336804

GI number: 158336804

Start: 3727840

End: 3728802

Strand: Reverse

Name: suhB [H]

Synonym: AM1_3672

Alternate gene names: 158336804

Gene position: 3728802-3727840 (Counterclockwise)

Preceding gene: 158336805

Following gene: 158336802

Centisome position: 57.33

GC content: 53.27

Gene sequence:

>963_bases
ATGATTATGCCCTACGAATCTGAGAGAAATATCGCCATCCAAGCTGTACAAGCGGCAGCCCACCTTTGCGAACAAGTGCG
GCGCGAAATTGTCCCAGAAGCCATTGAGAAGAAAGATAAAAGCCCGGTAACCGTGGCTGACTTTGGCGCTCAAGCTCTAA
TTTGTCGAGCCTTATCTACAGCTTTTCCTCAAGATCCCGTGGTGGGTGAAGAGGATGCCGCAGACTTACGAACTCCGGAG
ATGACTGAGCGATTAGCCCAGGTCACTCAATATGTGCAGGCCATTGTTCCCGATGCCACGCCTGATCAAGTCACTGGCTG
GATTGACCATGGCAATGGTCAGGTAGGATCACGCTACTGGACTTTAGATCCCATTGACGGCACCAAAGGGTTCCTGCGTG
GGGATCAATATGCCATCGCCTTAGCCTTAATTGAAAATGGCGAAATTAAAGTCGGCGTTTTGGGCTGTCCAGCCCTCTCT
TTTACAGAGGGTCAAACGGGGCTCATGGGCGTTGCCGTGCGCGGAGCCGGCGCAACCCTATCTCCTTTAGCAGGGGGAGC
CCCTCAATCTATAAAAGTCGTCTCTGCGGATCAATCTGACCATCTCCGCTTTGTAGAAAGCGTAGAATCCGGCCATGGCG
ATCAGTCCCGCCAAGCCGCTGTTGCCAAAGCAGCAGGTATCACCCAAGACTCCCTACGAATGGATAGCCAAGCCAAATAT
ATGGCGGTTGCTGCTGGAGAAGCCGCCCTCTATTTGCGGCTCCCCTCTCCCAAAACCCCTGATTATCGCGAGAAGATTTG
GGACCATGCCGCAGGGGTGATTTTAGTAGAAGAAGCGGGCGGTCGAGTAACAGATATTACCGGTCAAGCCCTCGACTTCT
CCCTAGGCGCAAAACTGGTGAACAACCAAGGGGTCGTCGTCAGCAATGGCAGCATCCATGATCCGGTGCTAGCCGCTCTC
TAA

Upstream 100 bases:

>100_bases
TAGTCAAAAGCGTCTCCACCTGGGCTGACCCTCTGTCTTCAGATTGACTGGTTTCACCCTAGCGAATCAGCTATGGTAGA
CATTGCCCTGTTGACGCCAC

Downstream 100 bases:

>100_bases
GCATTCAGGTAAAATTCAGGGCTTAAAGATCTGAGTGGTGATTTGCTCCAACTGTTTAAGCCCTTTGAGAGATCCTCGAA
TCAGTCGCAGGGCGGGCAGT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIMPYESERNIAIQAVQAAAHLCEQVRREIVPEAIEKKDKSPVTVADFGAQALICRALSTAFPQDPVVGEEDAADLRTPE
MTERLAQVTQYVQAIVPDATPDQVTGWIDHGNGQVGSRYWTLDPIDGTKGFLRGDQYAIALALIENGEIKVGVLGCPALS
FTEGQTGLMGVAVRGAGATLSPLAGGAPQSIKVVSADQSDHLRFVESVESGHGDQSRQAAVAKAAGITQDSLRMDSQAKY
MAVAAGEAALYLRLPSPKTPDYREKIWDHAAGVILVEEAGGRVTDITGQALDFSLGAKLVNNQGVVVSNGSIHDPVLAAL

Sequences:

>Translated_320_residues
MIMPYESERNIAIQAVQAAAHLCEQVRREIVPEAIEKKDKSPVTVADFGAQALICRALSTAFPQDPVVGEEDAADLRTPE
MTERLAQVTQYVQAIVPDATPDQVTGWIDHGNGQVGSRYWTLDPIDGTKGFLRGDQYAIALALIENGEIKVGVLGCPALS
FTEGQTGLMGVAVRGAGATLSPLAGGAPQSIKVVSADQSDHLRFVESVESGHGDQSRQAAVAKAAGITQDSLRMDSQAKY
MAVAAGEAALYLRLPSPKTPDYREKIWDHAAGVILVEEAGGRVTDITGQALDFSLGAKLVNNQGVVVSNGSIHDPVLAAL
>Mature_320_residues
MIMPYESERNIAIQAVQAAAHLCEQVRREIVPEAIEKKDKSPVTVADFGAQALICRALSTAFPQDPVVGEEDAADLRTPE
MTERLAQVTQYVQAIVPDATPDQVTGWIDHGNGQVGSRYWTLDPIDGTKGFLRGDQYAIALALIENGEIKVGVLGCPALS
FTEGQTGLMGVAVRGAGATLSPLAGGAPQSIKVVSADQSDHLRFVESVESGHGDQSRQAAVAKAAGITQDSLRMDSQAKY
MAVAAGEAALYLRLPSPKTPDYREKIWDHAAGVILVEEAGGRVTDITGQALDFSLGAKLVNNQGVVVSNGSIHDPVLAAL

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=271, Percent_Identity=26.5682656826568, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324508, Length=350, Percent_Identity=37.1428571428571, Blast_Score=198, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 33810; Mature: 33810

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMPYESERNIAIQAVQAAAHLCEQVRREIVPEAIEKKDKSPVTVADFGAQALICRALST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
AFPQDPVVGEEDAADLRTPEMTERLAQVTQYVQAIVPDATPDQVTGWIDHGNGQVGSRYW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEE
TLDPIDGTKGFLRGDQYAIALALIENGEIKVGVLGCPALSFTEGQTGLMGVAVRGAGATL
EECCCCCCCHHHCCCCEEEEEEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCCCCC
SPLAGGAPQSIKVVSADQSDHLRFVESVESGHGDQSRQAAVAKAAGITQDSLRMDSQAKY
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCE
MAVAAGEAALYLRLPSPKTPDYREKIWDHAAGVILVEEAGGRVTDITGQALDFSLGAKLV
EEEEECCEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCCEEEECCCCCEEHHHCHHEE
NNQGVVVSNGSIHDPVLAAL
CCCCEEEECCCCCCCHHHCC
>Mature Secondary Structure
MIMPYESERNIAIQAVQAAAHLCEQVRREIVPEAIEKKDKSPVTVADFGAQALICRALST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
AFPQDPVVGEEDAADLRTPEMTERLAQVTQYVQAIVPDATPDQVTGWIDHGNGQVGSRYW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEE
TLDPIDGTKGFLRGDQYAIALALIENGEIKVGVLGCPALSFTEGQTGLMGVAVRGAGATL
EECCCCCCCHHHCCCCEEEEEEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCCCCC
SPLAGGAPQSIKVVSADQSDHLRFVESVESGHGDQSRQAAVAKAAGITQDSLRMDSQAKY
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCE
MAVAAGEAALYLRLPSPKTPDYREKIWDHAAGVILVEEAGGRVTDITGQALDFSLGAKLV
EEEEECCEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCCEEEECCCCCEEHHHCHHEE
NNQGVVVSNGSIHDPVLAAL
CCCCEEEECCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]