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The map label for this gene is yoeA [H]

Identifier: 158336728

GI number: 158336728

Start: 3651489

End: 3652871

Strand: Reverse

Name: yoeA [H]

Synonym: AM1_3596

Alternate gene names: 158336728

Gene position: 3652871-3651489 (Counterclockwise)

Preceding gene: 158336729

Following gene: 158336721

Centisome position: 56.17

GC content: 49.89

Gene sequence:

>1383_bases
ATGCCCCAACCTACTCCCCCAAGAACCGTGAGACAGCGATTAACGGAAGGCAATGTTAGTGCCCAATTGATAAAACTTAC
CTTGCCGCTGGTGTGGGGGATTTTTACGATTGTTGCCTTCAATTTGGCAGACACCTATTTTGTAGGTCAGCTCGGTACTC
AAGAACTGGCAGCCATGAGTTTCACCTTTCCCGTGGTCACAACGTTTGGCAGCTTAGCCATGGGATTGGGAACGGGAGCA
GCTTCAATTATTGCCCGAGCGATTGGTGAAGGCGATCAAACCCGGGTACAGCGCTTTACCACCAATAGTTTGACGTTGGC
TCTAGCTATTGTTGGGGTTTTTATTGTGGTGGGCCTATTGACGATTGATCCACTCTTCACGGCTTTGGGAGCAACGCCAG
ACGTTCTTCCCCTGGTGCGGGACTATATGCAGATCTGGTATCTGGGTATGATTTTCTTGGTGGTGCCGATGGTGGGGAAC
AGCGCCATCCGTGCAGCCGGGAATACGGCTACCCCCAGCATCATTATGACCGTCGCCGCGGGTATTAATATTGCCTTAGA
TCCCCTGTTTATCCTAGGTTTAGCGGGCTTACCGCGCTTAGAACTTCAGGGGGCCGCCATCGCAACAGTGATTGCCCGCG
CCCTCACCTTTATTGCCTCTCTTGTTGTTCTCCATTTCAAAGAGCATCTGCTCTGCTTCCAACGCCCTAAGCTATCGGAG
ATGCTGAGATGCTGGTTGGATATCCTCCGTATTGGTCTGCCAGCAGCCATGACTAGTATGATTACACCTATTTCTGTGGG
CATAATCACCAGTCTCCTGGCTTTTTATGGAGAAGAAGCTGTCGCCGCCTTTGGAGTAGCATCGCGAGTAGAATCATTCG
CATTGATCACATTATTTGCCTTGGCAGCAAGTATGGGACCTTTTGTGGGGCAAAACTGGGGCGCCAAAGCTTATAGTCGG
GTGCAGCGTTCCCTTAAAGTCAGCTTCCAGTTTTGTTTATTTTGGGGCATGTTGATGGCGGTGTTGTTGGCAGCCACCGG
CAAGCAATTGGTGAGTTCGTTTAATGGCAACCCTGAGGTGGTTGCGATCGCAGCCCTATATCTCCTCATCGTGCCTATTA
CCTATGCTCCAGCAGGAATTATTCAAGTCTCCAGCGCCACCTTTAATGCCTTAGGTAAACCCATTCCTTCCGTGGTCATG
ACGGCCATCAGAATGTTTGTACTCTATATTCCGATGGCTTATTTAGGGTCACACTTCTTTGGTATTCAAGGCATTTTTAT
CGCCACGGGCCTGTCTAACCTTCTGACTGGGGTGGGTGCTTATTTTTGGAATCAAAGAACCTGCAATCTCCGACAAGCAG
TACCGCTAGAATCTGCAGTATGA

Upstream 100 bases:

>100_bases
AGCGGCTGTGCGGTGAGTGGGCAAAATGCTTTAAGATTTGTAAAGAAATGCAACGATGTTGAGTGAGATTGGACCCAAAG
CTGGGCATCGTTGGATCTAA

Downstream 100 bases:

>100_bases
TTCGAAGTCTTGTGTTGAACGTATTGGCATCACACCCCCTTCACAAAATTTGATATGAGTTCGAGCAATTTTTCAGGTGC
ATCTGCCCGAACCGAATGGC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MPQPTPPRTVRQRLTEGNVSAQLIKLTLPLVWGIFTIVAFNLADTYFVGQLGTQELAAMSFTFPVVTTFGSLAMGLGTGA
ASIIARAIGEGDQTRVQRFTTNSLTLALAIVGVFIVVGLLTIDPLFTALGATPDVLPLVRDYMQIWYLGMIFLVVPMVGN
SAIRAAGNTATPSIIMTVAAGINIALDPLFILGLAGLPRLELQGAAIATVIARALTFIASLVVLHFKEHLLCFQRPKLSE
MLRCWLDILRIGLPAAMTSMITPISVGIITSLLAFYGEEAVAAFGVASRVESFALITLFALAASMGPFVGQNWGAKAYSR
VQRSLKVSFQFCLFWGMLMAVLLAATGKQLVSSFNGNPEVVAIAALYLLIVPITYAPAGIIQVSSATFNALGKPIPSVVM
TAIRMFVLYIPMAYLGSHFFGIQGIFIATGLSNLLTGVGAYFWNQRTCNLRQAVPLESAV

Sequences:

>Translated_460_residues
MPQPTPPRTVRQRLTEGNVSAQLIKLTLPLVWGIFTIVAFNLADTYFVGQLGTQELAAMSFTFPVVTTFGSLAMGLGTGA
ASIIARAIGEGDQTRVQRFTTNSLTLALAIVGVFIVVGLLTIDPLFTALGATPDVLPLVRDYMQIWYLGMIFLVVPMVGN
SAIRAAGNTATPSIIMTVAAGINIALDPLFILGLAGLPRLELQGAAIATVIARALTFIASLVVLHFKEHLLCFQRPKLSE
MLRCWLDILRIGLPAAMTSMITPISVGIITSLLAFYGEEAVAAFGVASRVESFALITLFALAASMGPFVGQNWGAKAYSR
VQRSLKVSFQFCLFWGMLMAVLLAATGKQLVSSFNGNPEVVAIAALYLLIVPITYAPAGIIQVSSATFNALGKPIPSVVM
TAIRMFVLYIPMAYLGSHFFGIQGIFIATGLSNLLTGVGAYFWNQRTCNLRQAVPLESAV
>Mature_459_residues
PQPTPPRTVRQRLTEGNVSAQLIKLTLPLVWGIFTIVAFNLADTYFVGQLGTQELAAMSFTFPVVTTFGSLAMGLGTGAA
SIIARAIGEGDQTRVQRFTTNSLTLALAIVGVFIVVGLLTIDPLFTALGATPDVLPLVRDYMQIWYLGMIFLVVPMVGNS
AIRAAGNTATPSIIMTVAAGINIALDPLFILGLAGLPRLELQGAAIATVIARALTFIASLVVLHFKEHLLCFQRPKLSEM
LRCWLDILRIGLPAAMTSMITPISVGIITSLLAFYGEEAVAAFGVASRVESFALITLFALAASMGPFVGQNWGAKAYSRV
QRSLKVSFQFCLFWGMLMAVLLAATGKQLVSSFNGNPEVVAIAALYLLIVPITYAPAGIIQVSSATFNALGKPIPSVVMT
AIRMFVLYIPMAYLGSHFFGIQGIFIATGLSNLLTGVGAYFWNQRTCNLRQAVPLESAV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49146; Mature: 49015

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PQPTPPRTVRQRLTEGNVSAQLIKLTLPLVWGIFTIVAFNLADTYFVGQLGTQELAAMS
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FTFPVVTTFGSLAMGLGTGAASIIARAIGEGDQTRVQRFTTNSLTLALAIVGVFIVVGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIDPLFTALGATPDVLPLVRDYMQIWYLGMIFLVVPMVGNSAIRAAGNTATPSIIMTVAA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHH
GINIALDPLFILGLAGLPRLELQGAAIATVIARALTFIASLVVLHFKEHLLCFQRPKLSE
CCCHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MLRCWLDILRIGLPAAMTSMITPISVGIITSLLAFYGEEAVAAFGVASRVESFALITLFA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LAASMGPFVGQNWGAKAYSRVQRSLKVSFQFCLFWGMLMAVLLAATGKQLVSSFNGNPEV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VAIAALYLLIVPITYAPAGIIQVSSATFNALGKPIPSVVMTAIRMFVLYIPMAYLGSHFF
HHHHHHHHHHHHHHCCCCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
GIQGIFIATGLSNLLTGVGAYFWNQRTCNLRQAVPLESAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]