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The map label for this gene is plsC [H]

Identifier: 158336647

GI number: 158336647

Start: 3557333

End: 3557971

Strand: Direct

Name: plsC [H]

Synonym: AM1_3515

Alternate gene names: 158336647

Gene position: 3557333-3557971 (Clockwise)

Preceding gene: 158336646

Following gene: 158336648

Centisome position: 54.7

GC content: 53.05

Gene sequence:

>639_bases
ATGCCACAACAGCGTGAGCCCACAATTAGCTTAGCCCTCTACCACCTGTTCAAATGGACGGTGGTCAGCCCCTCTTTACA
TGTTTATTTTCGGGGGCGTATTCACAATGCCGAACGGGTGCCCCAGCAAGGTCCACTCGTGGTGGTGAGTAACCATGCGA
GTGACTTTGATCCACCGCTTGTATCCAACTGCATGCGTCGGCCTGTGGCATTTATGGCCAAACAGGAACTCTTTGAGGTG
CCGGTTTTATCCACTTTGATTCGGTGGTATGGTGCCTATCCTGTGAATCGCGGATCGGCAGATCGCAGTGCGATTCGGGC
GGCCTTAGCCTCCTTAGACCAAGGGTGGGCTGTGGGCCTATTTTTGCAGGGCACTCGTACAGCAGATGGGCGAATTTCTA
ACCCCAAGCAGGGAGCCGCTTTAATTGCTAGCAAGATTCAGGCCCCTTTACTGCCGGTTTGCCTATGGGGGACTGAAAAA
ATTATTCCCAAAGGTCAGAAATTCCCGCGTAGTGTACCGTTAACCATCCGCATTGGAGAGCCTATTCCCCCGCCGCCTAG
TCGCGATCGCACGGCACTGGCCGATGTGACTCAACACTGTGCCGATGTGATTAATGCCATGCATGATTTAGGTCGTTAA

Upstream 100 bases:

>100_bases
GGAGAGCCTACCTATGTGAATTTAGATAGGGTTTAACCGACCGGCCCAACCCCAATTTGATATGGTCAGTCTTATTGAGT
TCTTTGCCGAGGTTCGCCCC

Downstream 100 bases:

>100_bases
CGCCATGGAAAAGTGCTTTAAATCGATTCAATGGGGATTACTGTTAGGGATAACCCTCGCCATGGGTGCCTGTGGGTTGC
CAGAAGCCTTCAATCAGTTT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MPQQREPTISLALYHLFKWTVVSPSLHVYFRGRIHNAERVPQQGPLVVVSNHASDFDPPLVSNCMRRPVAFMAKQELFEV
PVLSTLIRWYGAYPVNRGSADRSAIRAALASLDQGWAVGLFLQGTRTADGRISNPKQGAALIASKIQAPLLPVCLWGTEK
IIPKGQKFPRSVPLTIRIGEPIPPPPSRDRTALADVTQHCADVINAMHDLGR

Sequences:

>Translated_212_residues
MPQQREPTISLALYHLFKWTVVSPSLHVYFRGRIHNAERVPQQGPLVVVSNHASDFDPPLVSNCMRRPVAFMAKQELFEV
PVLSTLIRWYGAYPVNRGSADRSAIRAALASLDQGWAVGLFLQGTRTADGRISNPKQGAALIASKIQAPLLPVCLWGTEK
IIPKGQKFPRSVPLTIRIGEPIPPPPSRDRTALADVTQHCADVINAMHDLGR
>Mature_211_residues
PQQREPTISLALYHLFKWTVVSPSLHVYFRGRIHNAERVPQQGPLVVVSNHASDFDPPLVSNCMRRPVAFMAKQELFEVP
VLSTLIRWYGAYPVNRGSADRSAIRAALASLDQGWAVGLFLQGTRTADGRISNPKQGAALIASKIQAPLLPVCLWGTEKI
IPKGQKFPRSVPLTIRIGEPIPPPPSRDRTALADVTQHCADVINAMHDLGR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 23382; Mature: 23251

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQQREPTISLALYHLFKWTVVSPSLHVYFRGRIHNAERVPQQGPLVVVSNHASDFDPPL
CCCCCCCHHHHHHHHHHHHHEECCCEEEEEEEEECCHHHCCCCCCEEEEECCCCCCCCHH
VSNCMRRPVAFMAKQELFEVPVLSTLIRWYGAYPVNRGSADRSAIRAALASLDQGWAVGL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
FLQGTRTADGRISNPKQGAALIASKIQAPLLPVCLWGTEKIIPKGQKFPRSVPLTIRIGE
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCEEEEECC
PIPPPPSRDRTALADVTQHCADVINAMHDLGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQQREPTISLALYHLFKWTVVSPSLHVYFRGRIHNAERVPQQGPLVVVSNHASDFDPPL
CCCCCCHHHHHHHHHHHHHEECCCEEEEEEEEECCHHHCCCCCCEEEEECCCCCCCCHH
VSNCMRRPVAFMAKQELFEVPVLSTLIRWYGAYPVNRGSADRSAIRAALASLDQGWAVGL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
FLQGTRTADGRISNPKQGAALIASKIQAPLLPVCLWGTEKIIPKGQKFPRSVPLTIRIGE
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCEEEEECC
PIPPPPSRDRTALADVTQHCADVINAMHDLGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]