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The map label for this gene is fabD [H]

Identifier: 158336646

GI number: 158336646

Start: 3556370

End: 3557251

Strand: Direct

Name: fabD [H]

Synonym: AM1_3514

Alternate gene names: 158336646

Gene position: 3556370-3557251 (Clockwise)

Preceding gene: 158336645

Following gene: 158336647

Centisome position: 54.68

GC content: 51.02

Gene sequence:

>882_bases
ATGACCAAAACAGCATGGGTATTTCCTGGGCAAGGGTCCCAGGCCATAGGTATGGGCCTCGACCTCCTTGACACCGAAAT
CGGCAAACAGCGGTTTGAAGCTGCAGCCAGCATCTTGGGATGGTCCGTCCCCGAAGTGTGCGGGGAGGATGAAACCCGCC
TCTCCCAAACGAATTACACCCAGCCTTGCTTATACGTGGTGTCTGCTATTTTTTCCGACCTATTAACCGAGAAAGGACTA
AAACCCGATTTGGTTGCGGGTCATAGTTTGGGAGAATACGTCGCCTTATACTCTGCCCAAGTCTTCGACTTTGAATCCGG
TTTAAAGCTCGTACAAAAGCGATCAACTCTGATGTCTCAAGCTTCGGATGGCAAAATGGCTGCTTTGATGGGGTTTGATC
GCGATCAGCTCAGTCAAACTGTTGATAGTAAAGATGGCGTGGTCTTGGCCAATGATAACCATGCAGGCCAAGTCGTCATT
TCCGGCACACCCGCTGCTGTGGATAGCGTCTTAGGCAGTATTAAAGTTAAGCGGGCAGTGGAGCTGAATGTCAGCGGTGC
CTTCCATTCACCTCTGATGGCGGATGCGGCGGCTGAATATGAATCAGTCCTCAATTCTATCGACTTTAAACCTGCCCAAG
TGCCCGTTGTCTCCAATGTAGAGCCAACGCCTTCAACCGATCCGGCTATCCTGCAAACTCGACTCATTCAGCAAATGACG
GGGCCTGTGCGTTGGCGAGAAACGGCCCTCGTCTTTGCCGATCAAGGGATTGAAGCTGTTATGGAAGTCGGACCGGGCAA
AGTCTTAACGGGGTTGGTCAAGCGGACCTGTAAAGAGATGGCTCTAACGAATATCAATAGTTTGGAGAGCCTACCTATGT
GA

Upstream 100 bases:

>100_bases
AAAAACGGTACAAGCGGAGTTGATACCCGCGAAAAAGTGTTATGAACGCTACCGTTCAGTGCAAAACTGGTAGGTGGAGC
TGACGCAATAATCTAAAAGT

Downstream 100 bases:

>100_bases
ATTTAGATAGGGTTTAACCGACCGGCCCAACCCCAATTTGATATGGTCAGTCTTATTGAGTTCTTTGCCGAGGTTCGCCC
CATGCCACAACAGCGTGAGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTKTAWVFPGQGSQAIGMGLDLLDTEIGKQRFEAAASILGWSVPEVCGEDETRLSQTNYTQPCLYVVSAIFSDLLTEKGL
KPDLVAGHSLGEYVALYSAQVFDFESGLKLVQKRSTLMSQASDGKMAALMGFDRDQLSQTVDSKDGVVLANDNHAGQVVI
SGTPAAVDSVLGSIKVKRAVELNVSGAFHSPLMADAAAEYESVLNSIDFKPAQVPVVSNVEPTPSTDPAILQTRLIQQMT
GPVRWRETALVFADQGIEAVMEVGPGKVLTGLVKRTCKEMALTNINSLESLPM

Sequences:

>Translated_293_residues
MTKTAWVFPGQGSQAIGMGLDLLDTEIGKQRFEAAASILGWSVPEVCGEDETRLSQTNYTQPCLYVVSAIFSDLLTEKGL
KPDLVAGHSLGEYVALYSAQVFDFESGLKLVQKRSTLMSQASDGKMAALMGFDRDQLSQTVDSKDGVVLANDNHAGQVVI
SGTPAAVDSVLGSIKVKRAVELNVSGAFHSPLMADAAAEYESVLNSIDFKPAQVPVVSNVEPTPSTDPAILQTRLIQQMT
GPVRWRETALVFADQGIEAVMEVGPGKVLTGLVKRTCKEMALTNINSLESLPM
>Mature_292_residues
TKTAWVFPGQGSQAIGMGLDLLDTEIGKQRFEAAASILGWSVPEVCGEDETRLSQTNYTQPCLYVVSAIFSDLLTEKGLK
PDLVAGHSLGEYVALYSAQVFDFESGLKLVQKRSTLMSQASDGKMAALMGFDRDQLSQTVDSKDGVVLANDNHAGQVVIS
GTPAAVDSVLGSIKVKRAVELNVSGAFHSPLMADAAAEYESVLNSIDFKPAQVPVVSNVEPTPSTDPAILQTRLIQQMTG
PVRWRETALVFADQGIEAVMEVGPGKVLTGLVKRTCKEMALTNINSLESLPM

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=314, Percent_Identity=29.6178343949045, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787334, Length=300, Percent_Identity=37, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=26.4604810996564, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=296, Percent_Identity=26.0135135135135, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24665753, Length=309, Percent_Identity=31.3915857605178, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31337; Mature: 31206

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAWVFPGQGSQAIGMGLDLLDTEIGKQRFEAAASILGWSVPEVCGEDETRLSQTNYT
CCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCCCC
QPCLYVVSAIFSDLLTEKGLKPDLVAGHSLGEYVALYSAQVFDFESGLKLVQKRSTLMSQ
CHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDGKMAALMGFDRDQLSQTVDSKDGVVLANDNHAGQVVISGTPAAVDSVLGSIKVKRAV
CCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHEEEE
ELNVSGAFHSPLMADAAAEYESVLNSIDFKPAQVPVVSNVEPTPSTDPAILQTRLIQQMT
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHC
GPVRWRETALVFADQGIEAVMEVGPGKVLTGLVKRTCKEMALTNINSLESLPM
CCCCCHHEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
TKTAWVFPGQGSQAIGMGLDLLDTEIGKQRFEAAASILGWSVPEVCGEDETRLSQTNYT
CCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCCCC
QPCLYVVSAIFSDLLTEKGLKPDLVAGHSLGEYVALYSAQVFDFESGLKLVQKRSTLMSQ
CHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDGKMAALMGFDRDQLSQTVDSKDGVVLANDNHAGQVVISGTPAAVDSVLGSIKVKRAV
CCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHEEEE
ELNVSGAFHSPLMADAAAEYESVLNSIDFKPAQVPVVSNVEPTPSTDPAILQTRLIQQMT
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHC
GPVRWRETALVFADQGIEAVMEVGPGKVLTGLVKRTCKEMALTNINSLESLPM
CCCCCHHEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]