Click here to switch to the map view.

The map label for this gene is hemR [H]

Identifier: 158336543

GI number: 158336543

Start: 3438840

End: 3441263

Strand: Reverse

Name: hemR [H]

Synonym: AM1_3407

Alternate gene names: 158336543

Gene position: 3441263-3438840 (Counterclockwise)

Preceding gene: 158336544

Following gene: 158336542

Centisome position: 52.91

GC content: 48.72

Gene sequence:

>2424_bases
TTGTTAACCTCAGATGACTGTCCCCTGGATGTCACTGCTGATGTCACGACTGGAGTAGAACCAACCGTCCCAACGGTTAT
TACGGCTGAGGGTATTCCTGACATTACAGAAATAGAGTTGCCCATATCAGATGCCCAACTCTTATCTCAAGAGAGTCCTG
ATGAAGCCGATCTCCCTGCTGCAGAAGAGGAGGCAGCGCCGACTGACACCGTGGATGAAGAAGTAGAGCTGGAAATTACA
GTGACTGGCACGCGGACGCCACGGGCCATTCAACTCTCTCCAGCCAATGTCACTGTCATCAAAGCGGAGGAGCTACAGCG
TCAGTTAGGCCAAGATATTCGGGATTTAATCCGCTATGAGCCAGGGGTAAGCGTGAATGAAGATGAGACCTATGGCGCAA
CGGATTACAACATTCGCGGTTTAGAACGCAATCGAATTTTGCTGCAGGTGGATGGGATTCGACTCCCCACCTTTTTTGAA
TTTGGCAGTTCGATTTTAGGGCGCGATTTTGTCGATGTGGGTTCAGTACAGACGACGGAAATTATTCGAGGCCCCGCCTC
TGCGCTCTATGGGAGTGATGCCTTAGGAGGGGTGGTCAGCTACCTAACCCCAGACCCCAGTGACCTATTGGCATTAACAG
ATCGCGATTACTACATTAGCGGGTCTACCCAGTTTCGAAGTTCAAATTCCGGGTTTTCGGGTACGGGCACCGTTGCCTTT
CGGGCCACGGACAATCTGTCTGGATTAGTGCGCTTTACCCATCGCGAAAACACCGAGCGGGATAATAATGCCGAGGATCG
ATTTGAAGATCCGTTTTTCGGGGTGACCAATAATGTATTGGGCAAGCTGGAATTTAAGATCAATGACTATAATACCGTCC
TGCTTACAGGTGAATATTTCAATGAAGCGGGTGACTTCGATACAGCAGTCGATAATCTTAACCTCCCCTTAGCCTTTCCT
GGCATAACGATTCTGAGCGATGATACCGATACGGAAACGACGCGATCGCGCTTTAGTATCGCTTACAAATTTGACAATCC
TGAAAGTGAAAGTTTCTTACAATTTGGTCGAGTCCAGTTCTACTATCAGGAATCGGATTACCAAGAAACCCGCACTAGAA
ATGATATTTTTGCCAATCCCTTTGTGCCACCACCCTTTACTCCGCCCCCAGCCCGACGGTTTCGAGAGTTAAATAACCTG
TTCGTTGAAGACATTATTGGTGGCGATATCCAGTTGCGGAGTGATTTTCGCACGGGCAGCGTCGCTCATAAACTCACCTA
TGGATTAGATATTTCTAGCACCTTTAACCAACGGATTCGAGATGGACAGCGCATTAACTTAGATACGGGTGCCGTCTCCA
ACCGAGTTGGACCGGATGCGTTTCCAATCAAAGACTTTCCTGATTCCGACACCCTGCGTATCGGAGTTTATCTACAAGAT
GAAATTGAATTTGGCGAAGGCCGATTTACGGTTATTCCAGGACTGCGCTTTGACTACTACAGTCTGACAACCCAACCGGA
TGCTCTCTTCTTCAATAATCCTGGTGCTGAGGCGACTGACTTAAATGATTCGGCCCTGTCTCCCAGCTTAGGCTTGGTCT
ACAAGGTCACTCCAGAAATTGCCTTAGTCGGTCGATATGCTCGGGGGTTTCGGGGACCCAACTACATTGAAATCAATAGC
GGTTTTTCTAACCCAGAAAGCGGATATCGCACCATTTCTAACCCTAATCTAGAGCCAGAAACCAGTCATACCTTTGAACT
AGGGGTTAAAGGAGCCTTTCCACGGGGTACCTTTGGCGTGACCGGGTTCTACAGCATCTATGACAATTTTATCTTTGGGG
CTGCGGAAGGTAGCACCGCAGGCACAGAACCTGCAGGATGTTTCCCACCCTTTACGCCAGGATGTGTGCAGGTATTTCAA
TCTCAAAATCTGGAGCAGGTCCGTATTTATGGAATTGAAGCTCAAGGGGAATATCGTTTCAGCTCCGAGCCCCATGGATT
CCGAATCTTTGGGGGGCTAGCCTGGATTATTGGCGATGATGATCAAAATAATCAGCCTTTGGAAACTGTGAATCCCTTTG
AAGCGGTTGTGGGATTAGGGTATCGAGCGCCAGAAGATCAATGGGGGGCAGAGTTGATTGGTACCTTTGTGGGTACTGCT
CGTGTAGATTCCGAACCAGAAGATTTTATTCCGGGAGGGTTTGCAGTGGTTGACTTGACGGGTTTTGTCAAAGTTACCCC
GAACCTCAGTCTCCGAGGCGGAATCTACAATATATTCGATGCGGAATATGTGCGCTATGCGGATGCCCGCAGACTCAATA
ATGAAACGAACAATACCACCACCGATCCGACGTTTGGTCAGCGGCGGGCTCGCATTACCCAACCTGGCATTAATTTCGGG
GTTGGCCTGACGTTTGAATTCTAG

Upstream 100 bases:

>100_bases
ACTCCTTACAGGTGCTGGTATGCTTAATGCTCAGCCAGTCTTGTCCCAAGTTGAAGATAAACCGTTAGACATAACAAAAC
AGTCAAACCAAACACGCTGT

Downstream 100 bases:

>100_bases
GCATATGGCACTTTTTCTGAAGGCAGCAGAGTTCACCCAGCTTTGTCAGCAGGGTCAAATAGAGTCTTCGTCTAGCACCG
GATTAGATCGCTCAACTCTG

Product: TonB-dependent outer membrane receptor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MLTSDDCPLDVTADVTTGVEPTVPTVITAEGIPDITEIELPISDAQLLSQESPDEADLPAAEEEAAPTDTVDEEVELEIT
VTGTRTPRAIQLSPANVTVIKAEELQRQLGQDIRDLIRYEPGVSVNEDETYGATDYNIRGLERNRILLQVDGIRLPTFFE
FGSSILGRDFVDVGSVQTTEIIRGPASALYGSDALGGVVSYLTPDPSDLLALTDRDYYISGSTQFRSSNSGFSGTGTVAF
RATDNLSGLVRFTHRENTERDNNAEDRFEDPFFGVTNNVLGKLEFKINDYNTVLLTGEYFNEAGDFDTAVDNLNLPLAFP
GITILSDDTDTETTRSRFSIAYKFDNPESESFLQFGRVQFYYQESDYQETRTRNDIFANPFVPPPFTPPPARRFRELNNL
FVEDIIGGDIQLRSDFRTGSVAHKLTYGLDISSTFNQRIRDGQRINLDTGAVSNRVGPDAFPIKDFPDSDTLRIGVYLQD
EIEFGEGRFTVIPGLRFDYYSLTTQPDALFFNNPGAEATDLNDSALSPSLGLVYKVTPEIALVGRYARGFRGPNYIEINS
GFSNPESGYRTISNPNLEPETSHTFELGVKGAFPRGTFGVTGFYSIYDNFIFGAAEGSTAGTEPAGCFPPFTPGCVQVFQ
SQNLEQVRIYGIEAQGEYRFSSEPHGFRIFGGLAWIIGDDDQNNQPLETVNPFEAVVGLGYRAPEDQWGAELIGTFVGTA
RVDSEPEDFIPGGFAVVDLTGFVKVTPNLSLRGGIYNIFDAEYVRYADARRLNNETNNTTTDPTFGQRRARITQPGINFG
VGLTFEF

Sequences:

>Translated_807_residues
MLTSDDCPLDVTADVTTGVEPTVPTVITAEGIPDITEIELPISDAQLLSQESPDEADLPAAEEEAAPTDTVDEEVELEIT
VTGTRTPRAIQLSPANVTVIKAEELQRQLGQDIRDLIRYEPGVSVNEDETYGATDYNIRGLERNRILLQVDGIRLPTFFE
FGSSILGRDFVDVGSVQTTEIIRGPASALYGSDALGGVVSYLTPDPSDLLALTDRDYYISGSTQFRSSNSGFSGTGTVAF
RATDNLSGLVRFTHRENTERDNNAEDRFEDPFFGVTNNVLGKLEFKINDYNTVLLTGEYFNEAGDFDTAVDNLNLPLAFP
GITILSDDTDTETTRSRFSIAYKFDNPESESFLQFGRVQFYYQESDYQETRTRNDIFANPFVPPPFTPPPARRFRELNNL
FVEDIIGGDIQLRSDFRTGSVAHKLTYGLDISSTFNQRIRDGQRINLDTGAVSNRVGPDAFPIKDFPDSDTLRIGVYLQD
EIEFGEGRFTVIPGLRFDYYSLTTQPDALFFNNPGAEATDLNDSALSPSLGLVYKVTPEIALVGRYARGFRGPNYIEINS
GFSNPESGYRTISNPNLEPETSHTFELGVKGAFPRGTFGVTGFYSIYDNFIFGAAEGSTAGTEPAGCFPPFTPGCVQVFQ
SQNLEQVRIYGIEAQGEYRFSSEPHGFRIFGGLAWIIGDDDQNNQPLETVNPFEAVVGLGYRAPEDQWGAELIGTFVGTA
RVDSEPEDFIPGGFAVVDLTGFVKVTPNLSLRGGIYNIFDAEYVRYADARRLNNETNNTTTDPTFGQRRARITQPGINFG
VGLTFEF
>Mature_807_residues
MLTSDDCPLDVTADVTTGVEPTVPTVITAEGIPDITEIELPISDAQLLSQESPDEADLPAAEEEAAPTDTVDEEVELEIT
VTGTRTPRAIQLSPANVTVIKAEELQRQLGQDIRDLIRYEPGVSVNEDETYGATDYNIRGLERNRILLQVDGIRLPTFFE
FGSSILGRDFVDVGSVQTTEIIRGPASALYGSDALGGVVSYLTPDPSDLLALTDRDYYISGSTQFRSSNSGFSGTGTVAF
RATDNLSGLVRFTHRENTERDNNAEDRFEDPFFGVTNNVLGKLEFKINDYNTVLLTGEYFNEAGDFDTAVDNLNLPLAFP
GITILSDDTDTETTRSRFSIAYKFDNPESESFLQFGRVQFYYQESDYQETRTRNDIFANPFVPPPFTPPPARRFRELNNL
FVEDIIGGDIQLRSDFRTGSVAHKLTYGLDISSTFNQRIRDGQRINLDTGAVSNRVGPDAFPIKDFPDSDTLRIGVYLQD
EIEFGEGRFTVIPGLRFDYYSLTTQPDALFFNNPGAEATDLNDSALSPSLGLVYKVTPEIALVGRYARGFRGPNYIEINS
GFSNPESGYRTISNPNLEPETSHTFELGVKGAFPRGTFGVTGFYSIYDNFIFGAAEGSTAGTEPAGCFPPFTPGCVQVFQ
SQNLEQVRIYGIEAQGEYRFSSEPHGFRIFGGLAWIIGDDDQNNQPLETVNPFEAVVGLGYRAPEDQWGAELIGTFVGTA
RVDSEPEDFIPGGFAVVDLTGFVKVTPNLSLRGGIYNIFDAEYVRYADARRLNNETNNTTTDPTFGQRRARITQPGINFG
VGLTFEF

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=140, Percent_Identity=35.7142857142857, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790405, Length=128, Percent_Identity=35.15625, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786344, Length=481, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 89001; Mature: 89001

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSDDCPLDVTADVTTGVEPTVPTVITAEGIPDITEIELPISDAQLLSQESPDEADLPA
CCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCCCC
AEEEAAPTDTVDEEVELEITVTGTRTPRAIQLSPANVTVIKAEELQRQLGQDIRDLIRYE
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCC
PGVSVNEDETYGATDYNIRGLERNRILLQVDGIRLPTFFEFGSSILGRDFVDVGSVQTTE
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEECCHHHHHHHHHHCCCCCCCCCCEEHH
IIRGPASALYGSDALGGVVSYLTPDPSDLLALTDRDYYISGSTQFRSSNSGFSGTGTVAF
HHCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEECCCCCCCCCCEEEEE
RATDNLSGLVRFTHRENTERDNNAEDRFEDPFFGVTNNVLGKLEFKINDYNTVLLTGEYF
EECCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEECHHH
NEAGDFDTAVDNLNLPLAFPGITILSDDTDTETTRSRFSIAYKFDNPESESFLQFGRVQF
CCCCCCHHHHHCCCCCEECCCEEEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHCCEEE
YYQESDYQETRTRNDIFANPFVPPPFTPPPARRFRELNNLFVEDIIGGDIQLRSDFRTGS
EEECCCHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
VAHKLTYGLDISSTFNQRIRDGQRINLDTGAVSNRVGPDAFPIKDFPDSDTLRIGVYLQD
EEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
EIEFGEGRFTVIPGLRFDYYSLTTQPDALFFNNPGAEATDLNDSALSPSLGLVYKVTPEI
CEECCCCCEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCE
ALVGRYARGFRGPNYIEINSGFSNPESGYRTISNPNLEPETSHTFELGVKGAFPRGTFGV
EEEEHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCC
TGFYSIYDNFIFGAAEGSTAGTEPAGCFPPFTPGCVQVFQSQNLEQVRIYGIEAQGEYRF
CCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEE
SSEPHGFRIFGGLAWIIGDDDQNNQPLETVNPFEAVVGLGYRAPEDQWGAELIGTFVGTA
CCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHE
RVDSEPEDFIPGGFAVVDLTGFVKVTPNLSLRGGIYNIFDAEYVRYADARRLNNETNNTT
ECCCCCHHCCCCCEEEEEEEEEEEECCCCEECCCEEEECCCHHHHHHHHHHHCCCCCCCC
TDPTFGQRRARITQPGINFGVGLTFEF
CCCCCCCCCCEECCCCCCCCEEEEEEC
>Mature Secondary Structure
MLTSDDCPLDVTADVTTGVEPTVPTVITAEGIPDITEIELPISDAQLLSQESPDEADLPA
CCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCCCC
AEEEAAPTDTVDEEVELEITVTGTRTPRAIQLSPANVTVIKAEELQRQLGQDIRDLIRYE
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCC
PGVSVNEDETYGATDYNIRGLERNRILLQVDGIRLPTFFEFGSSILGRDFVDVGSVQTTE
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEECCHHHHHHHHHHCCCCCCCCCCEEHH
IIRGPASALYGSDALGGVVSYLTPDPSDLLALTDRDYYISGSTQFRSSNSGFSGTGTVAF
HHCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEECCCCCCCCCCEEEEE
RATDNLSGLVRFTHRENTERDNNAEDRFEDPFFGVTNNVLGKLEFKINDYNTVLLTGEYF
EECCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEECHHH
NEAGDFDTAVDNLNLPLAFPGITILSDDTDTETTRSRFSIAYKFDNPESESFLQFGRVQF
CCCCCCHHHHHCCCCCEECCCEEEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHCCEEE
YYQESDYQETRTRNDIFANPFVPPPFTPPPARRFRELNNLFVEDIIGGDIQLRSDFRTGS
EEECCCHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
VAHKLTYGLDISSTFNQRIRDGQRINLDTGAVSNRVGPDAFPIKDFPDSDTLRIGVYLQD
EEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
EIEFGEGRFTVIPGLRFDYYSLTTQPDALFFNNPGAEATDLNDSALSPSLGLVYKVTPEI
CEECCCCCEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCE
ALVGRYARGFRGPNYIEINSGFSNPESGYRTISNPNLEPETSHTFELGVKGAFPRGTFGV
EEEEHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCC
TGFYSIYDNFIFGAAEGSTAGTEPAGCFPPFTPGCVQVFQSQNLEQVRIYGIEAQGEYRF
CCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEE
SSEPHGFRIFGGLAWIIGDDDQNNQPLETVNPFEAVVGLGYRAPEDQWGAELIGTFVGTA
CCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHE
RVDSEPEDFIPGGFAVVDLTGFVKVTPNLSLRGGIYNIFDAEYVRYADARRLNNETNNTT
ECCCCCHHCCCCCEEEEEEEEEEEECCCCEECCCEEEECCCHHHHHHHHHHHCCCCCCCC
TDPTFGQRRARITQPGINFGVGLTFEF
CCCCCCCCCCEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1425573 [H]