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The map label for this gene is 158336508

Identifier: 158336508

GI number: 158336508

Start: 3403076

End: 3404116

Strand: Direct

Name: 158336508

Synonym: AM1_3372

Alternate gene names: NA

Gene position: 3403076-3404116 (Clockwise)

Preceding gene: 158336501

Following gene: 158336509

Centisome position: 52.33

GC content: 52.64

Gene sequence:

>1041_bases
ATGAGTACCTATGCCCAAGAGTTAAAGGCCACCGCTAAAGCCTTGGTGGCAGCAGGGAAGGGCATCTTGGCAATTGATGA
GAGTAATGGCACTTGTAATAAGCGATTCGCTCAGCTCAGCATTCCTACAACGGAAGAGAATCGCAGAGCTTATCGAGAGT
TAATCTTAACAACACCCCAGCTTTCTACTTACATCAGTGGCCCCATCTTGTTTGATGAGACTATTCGACAGTCCACTAGG
AACGGCAAATCCTTTGTACAAGTGATTACTGAAGTGGGTATGCTTCCGGGGATTAAGGTGGACACGGGAGCTAAAGACTT
GGCTGCCCATCGGGATGAAAAGGTAACGGAAGGTCTAGATGGCTTGCGCGAGCGCATTGCTGAGTACTACAGCATGGGCG
CTCGGTTTGCGAAATGGCGGGCTGTGATTACCATTGGAGACGGTATTCCGAGCCAGGCTTGCATCAGTGTGAATGCCCAA
GCTTTGGCCCGCTATGCGGCCCTGTGCCAAGAGGGAGGTCTCGTTCCCATCGTCGAACCCGAAGTTTTAATTGACGGTGA
CCATACCCTAGAACGGTGCTACCAGGTGACGGATCGCACCCTTCATGCTGTGTTTGGTCAACTCTATGCTCAGGGAGTGG
CTTTTGACCAAATGATTCTTAAACCCAGCATGGTTGTTGCGGGTAAAGAGTGCCCACAGCAGCCGAGTGTGGATGAGGTT
GCTGAAGCAACCATCAATTGTCTACGCAAAAACGTGCCTGCTCCGGTTGCGGGAGTGGCCTTTTTGTCGGGTGGTCAAAG
TGCTGAGCGATCCGCTGCCCACCTGAATATCATGAACGCTCGCTATGCCGGTATCTGTCCCTGGCCTGTTACCTTTTCCT
ATGCCCGAGCCATTCAGCAGCCAGCATTGGAGCATTGGCGGGGTGAGAGCCAGCGGGTATCTGAAGCTCAACAGCGCCTG
TTGCATCGCGCCAAATGCAATAGTGCCGCCAGTCTGGGTGAATATAGCCCCGAGGTTGAGCGAGAACTAGCCCTCGTCTA
A

Upstream 100 bases:

>100_bases
AGCTGGATGAAATGACTTGACAATCCCATTTATTATTGACATTATATATCAATAAGCAAGAGATTTTAATTCCATCTCTG
CTCAAATTAGGAGGTTCGAT

Downstream 100 bases:

>100_bases
ATCATTCTCTTCTTACGCAGATCACACTGATCCTTAACACAGTCTACGTTCCCTGAGGAGTAACCGCATTTCTCAGGGAT
TTTCTTCTATCATCACCCGT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSTYAQELKATAKALVAAGKGILAIDESNGTCNKRFAQLSIPTTEENRRAYRELILTTPQLSTYISGPILFDETIRQSTR
NGKSFVQVITEVGMLPGIKVDTGAKDLAAHRDEKVTEGLDGLRERIAEYYSMGARFAKWRAVITIGDGIPSQACISVNAQ
ALARYAALCQEGGLVPIVEPEVLIDGDHTLERCYQVTDRTLHAVFGQLYAQGVAFDQMILKPSMVVAGKECPQQPSVDEV
AEATINCLRKNVPAPVAGVAFLSGGQSAERSAAHLNIMNARYAGICPWPVTFSYARAIQQPALEHWRGESQRVSEAQQRL
LHRAKCNSAASLGEYSPEVERELALV

Sequences:

>Translated_346_residues
MSTYAQELKATAKALVAAGKGILAIDESNGTCNKRFAQLSIPTTEENRRAYRELILTTPQLSTYISGPILFDETIRQSTR
NGKSFVQVITEVGMLPGIKVDTGAKDLAAHRDEKVTEGLDGLRERIAEYYSMGARFAKWRAVITIGDGIPSQACISVNAQ
ALARYAALCQEGGLVPIVEPEVLIDGDHTLERCYQVTDRTLHAVFGQLYAQGVAFDQMILKPSMVVAGKECPQQPSVDEV
AEATINCLRKNVPAPVAGVAFLSGGQSAERSAAHLNIMNARYAGICPWPVTFSYARAIQQPALEHWRGESQRVSEAQQRL
LHRAKCNSAASLGEYSPEVERELALV
>Mature_345_residues
STYAQELKATAKALVAAGKGILAIDESNGTCNKRFAQLSIPTTEENRRAYRELILTTPQLSTYISGPILFDETIRQSTRN
GKSFVQVITEVGMLPGIKVDTGAKDLAAHRDEKVTEGLDGLRERIAEYYSMGARFAKWRAVITIGDGIPSQACISVNAQA
LARYAALCQEGGLVPIVEPEVLIDGDHTLERCYQVTDRTLHAVFGQLYAQGVAFDQMILKPSMVVAGKECPQQPSVDEVA
EATINCLRKNVPAPVAGVAFLSGGQSAERSAAHLNIMNARYAGICPWPVTFSYARAIQQPALEHWRGESQRVSEAQQRLL
HRAKCNSAASLGEYSPEVERELALV

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=333, Percent_Identity=47.4474474474475, Blast_Score=301, Evalue=4e-82,
Organism=Homo sapiens, GI34577110, Length=333, Percent_Identity=47.4474474474475, Blast_Score=301, Evalue=4e-82,
Organism=Homo sapiens, GI4557305, Length=333, Percent_Identity=47.4474474474475, Blast_Score=301, Evalue=4e-82,
Organism=Homo sapiens, GI193794814, Length=333, Percent_Identity=47.4474474474475, Blast_Score=301, Evalue=4e-82,
Organism=Homo sapiens, GI4885063, Length=331, Percent_Identity=46.5256797583082, Blast_Score=292, Evalue=3e-79,
Organism=Homo sapiens, GI40354205, Length=335, Percent_Identity=44.4776119402985, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71983985, Length=329, Percent_Identity=46.2006079027356, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI25150450, Length=346, Percent_Identity=44.7976878612717, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI71983990, Length=230, Percent_Identity=46.0869565217391, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI45553577, Length=332, Percent_Identity=46.6867469879518, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI221459619, Length=331, Percent_Identity=46.2235649546828, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24650288, Length=331, Percent_Identity=46.2235649546828, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24650282, Length=330, Percent_Identity=46.3636363636364, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24650280, Length=330, Percent_Identity=46.3636363636364, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24650278, Length=330, Percent_Identity=46.3636363636364, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24650304, Length=332, Percent_Identity=42.4698795180723, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37678; Mature: 37547

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYAQELKATAKALVAAGKGILAIDESNGTCNKRFAQLSIPTTEENRRAYRELILTTPQ
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEEEECCCCHHHHHHHHHHHHCCCC
LSTYISGPILFDETIRQSTRNGKSFVQVITEVGMLPGIKVDTGAKDLAAHRDEKVTEGLD
HHHHHCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
GLRERIAEYYSMGARFAKWRAVITIGDGIPSQACISVNAQALARYAALCQEGGLVPIVEP
HHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEECC
EVLIDGDHTLERCYQVTDRTLHAVFGQLYAQGVAFDQMILKPSMVVAGKECPQQPSVDEV
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
AEATINCLRKNVPAPVAGVAFLSGGQSAERSAAHLNIMNARYAGICPWPVTFSYARAIQQ
HHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
PALEHWRGESQRVSEAQQRLLHRAKCNSAASLGEYSPEVERELALV
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure 
STYAQELKATAKALVAAGKGILAIDESNGTCNKRFAQLSIPTTEENRRAYRELILTTPQ
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEEEECCCCHHHHHHHHHHHHCCCC
LSTYISGPILFDETIRQSTRNGKSFVQVITEVGMLPGIKVDTGAKDLAAHRDEKVTEGLD
HHHHHCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
GLRERIAEYYSMGARFAKWRAVITIGDGIPSQACISVNAQALARYAALCQEGGLVPIVEP
HHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEECC
EVLIDGDHTLERCYQVTDRTLHAVFGQLYAQGVAFDQMILKPSMVVAGKECPQQPSVDEV
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
AEATINCLRKNVPAPVAGVAFLSGGQSAERSAAHLNIMNARYAGICPWPVTFSYARAIQQ
HHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
PALEHWRGESQRVSEAQQRLLHRAKCNSAASLGEYSPEVERELALV
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]