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The map label for this gene is moaE [H]

Identifier: 158336227

GI number: 158336227

Start: 3120038

End: 3120502

Strand: Direct

Name: moaE [H]

Synonym: AM1_3089

Alternate gene names: 158336227

Gene position: 3120038-3120502 (Clockwise)

Preceding gene: 158336226

Following gene: 158336233

Centisome position: 47.97

GC content: 53.12

Gene sequence:

>465_bases
ATGACTTCCTCTGTTGCTTCTACAGACGATCACTTTCTGATTACATTTGCTCCCCTGAGCGTCGAGGAAGTGTATCATCA
AGCCGATCATCCCCATAACGGCGCTGTGGTCGTCATGAGTGGCACCGTTCGTGACCAAACGGACGGTAAAGCCGTACTCT
CCCTGGAATATCAAGCCTATGAACCCATGGCCCTTAAAGTTTTCCAGAGCATTGCCCAGGATATTCGTCAGCGCTGGCCA
GAGGTCAACCGGATTGCTATCCATCACCGCACGGGTCATCTCAAAATTAGCGAGATTAGCGTCCTCGTTGCCGTGGGCTG
TCCCCATCGAGCTGAAGCCTTCACCGCCTGTCAATACGCCATCGACACCCTCAAGCACAATGCCCCCATCTGGAAAAAAG
AGCACTGGGCCGACGGTTCGAGTAGCTGGGTCAATATTGGGGCCTGTGAACAGGAAAACGCTTAG

Upstream 100 bases:

>100_bases
AGACGAGAGGGCCCTGAACCTTTTATCTGTCATCCTTCATCGCTTGATTAAGTCATTACGATAATCCGTCATGATAGAGA
AGCAGTGCCCTTCTCCCGCC

Downstream 100 bases:

>100_bases
GCTTAGTTTCCCTGCATTTGTTCTTTTAAAGACTCTAATGCAGCCCAGCGTCGATCAACGGGTTGCTCAATCTTCTCTGC
CTCTTTCAGCAAACCTTCAC

Product: molybdopterin converting factor 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTSSVASTDDHFLITFAPLSVEEVYHQADHPHNGAVVVMSGTVRDQTDGKAVLSLEYQAYEPMALKVFQSIAQDIRQRWP
EVNRIAIHHRTGHLKISEISVLVAVGCPHRAEAFTACQYAIDTLKHNAPIWKKEHWADGSSSWVNIGACEQENA

Sequences:

>Translated_154_residues
MTSSVASTDDHFLITFAPLSVEEVYHQADHPHNGAVVVMSGTVRDQTDGKAVLSLEYQAYEPMALKVFQSIAQDIRQRWP
EVNRIAIHHRTGHLKISEISVLVAVGCPHRAEAFTACQYAIDTLKHNAPIWKKEHWADGSSSWVNIGACEQENA
>Mature_153_residues
TSSVASTDDHFLITFAPLSVEEVYHQADHPHNGAVVVMSGTVRDQTDGKAVLSLEYQAYEPMALKVFQSIAQDIRQRWPE
VNRIAIHHRTGHLKISEISVLVAVGCPHRAEAFTACQYAIDTLKHNAPIWKKEHWADGSSSWVNIGACEQENA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:
GO:0006777: Molybdopterin converting factor, subunit 2

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=142, Percent_Identity=45.0704225352113, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1787003, Length=138, Percent_Identity=36.9565217391304, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509279, Length=136, Percent_Identity=37.5, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356259, Length=135, Percent_Identity=40.7407407407407, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17132; Mature: 17001

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSVASTDDHFLITFAPLSVEEVYHQADHPHNGAVVVMSGTVRDQTDGKAVLSLEYQAY
CCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCC
EPMALKVFQSIAQDIRQRWPEVNRIAIHHRTGHLKISEISVLVAVGCPHRAEAFTACQYA
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHEEEEEEECCCCCHHHHHHHHHH
IDTLKHNAPIWKKEHWADGSSSWVNIGACEQENA
HHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TSSVASTDDHFLITFAPLSVEEVYHQADHPHNGAVVVMSGTVRDQTDGKAVLSLEYQAY
CCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCC
EPMALKVFQSIAQDIRQRWPEVNRIAIHHRTGHLKISEISVLVAVGCPHRAEAFTACQYA
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHEEEEEEECCCCCHHHHHHHHHH
IDTLKHNAPIWKKEHWADGSSSWVNIGACEQENA
HHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]