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The map label for this gene is yciC [H]

Identifier: 158336208

GI number: 158336208

Start: 3093838

End: 3094875

Strand: Direct

Name: yciC [H]

Synonym: AM1_3070

Alternate gene names: 158336208

Gene position: 3093838-3094875 (Clockwise)

Preceding gene: 158336204

Following gene: 158336209

Centisome position: 47.57

GC content: 49.71

Gene sequence:

>1038_bases
ATGATTCAATCTCCCACTCAACAAGCCTCACCCCAAACCGATCTGAAACTTCCCAAACGAGGGTTGCCCGTGACAATTAT
TACGGGCTTCCTTGGCAGTGGGAAGACCACACTGCTCAACCATATTCTCCAAGACTGCCAGGATCTAAAAGTCGCGGTGT
TGGTCAATGAGTTTGGCGATATCGATATTGATAGCCAGCTCTTGGTTTCTGTTGAAGAAGATATGGTACAGCTCAGTAAT
GGCTGTATCTGCTGCACCATCAACGACGACTTGGTGGAAGCGGTCTACAGCATTTTGGAGCGGAACGAGAAGGTGGATCA
CTTGGTGATCGAAACAACGGGGGTGGCCGATCCATTGCCCATAGCACTCACGTTTGCGATGCCGCCCCTACGGAATTTAA
CCCAGCTAGATTCCATCGTCACGCTAGTGGATGCAGAAGCCTTCTCCCCCCAACATTTTGAGAGTGAAGCCGCCCTTAAT
CAAGTGTCCTATGCCGATATTATTGTGCTTAATAAAACGGACTTAGCTGCCCCTCAACAGGTAGATACGTTGGAGGCATG
GGTTCGAGAGCAGAAATGGGGGGCACGAATTTTGCGATCGCAAAACAGCAACATCCCCCTGCCATTGATTTTAGATACCA
ATCTCTTTCAGCCAGAGCGCTATACCGCAGAAGCAAAAGCAATGGCTGAGACGACGCATGATCACCATGCCCCTCACTGC
CACGACCACCACCATCACTCCAACCATCTCGTCAATGATGGGTTTGTATCGATGGCATTCGAAAGCGATCAACCGTTTGA
TTTGGACAAATTTCAAGATTGGCTCGCCGATGATCTGTCAGAAAACGTCTTCCGAGCTAAGGGATTCCTATGGTTTGGCA
CCATTACCCCCCGCTATATCTTCCAGCTCAGCGGCAAACGCTACACCTTAGACGCAGACAAGTGGCCTGGAATACCCAAG
ACACAGCTCGTCCTGATTGGTCGCGAGTTAGATGCCCCAAAACTACAGCATCAGCTTCGAGACTGTTTAACCTCTTAG

Upstream 100 bases:

>100_bases
CTCTCTGCTCCCAAGCGACCGTAAGACTATCTGCTGCAGCGATTCGCCCTGAAGCTTATACATCCAGAGCCAACTCACTC
ACCTCAACCGGAGTTCACTC

Downstream 100 bases:

>100_bases
CCGATCTCATCCACATCCATAACTCATAAAGAGTCTGAGCGAGATTCCTCAGGATTAACTGGGGGATCTAGCCAAAGCTG
AGGTTCTAACTCACTGCAGC

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MIQSPTQQASPQTDLKLPKRGLPVTIITGFLGSGKTTLLNHILQDCQDLKVAVLVNEFGDIDIDSQLLVSVEEDMVQLSN
GCICCTINDDLVEAVYSILERNEKVDHLVIETTGVADPLPIALTFAMPPLRNLTQLDSIVTLVDAEAFSPQHFESEAALN
QVSYADIIVLNKTDLAAPQQVDTLEAWVREQKWGARILRSQNSNIPLPLILDTNLFQPERYTAEAKAMAETTHDHHAPHC
HDHHHHSNHLVNDGFVSMAFESDQPFDLDKFQDWLADDLSENVFRAKGFLWFGTITPRYIFQLSGKRYTLDADKWPGIPK
TQLVLIGRELDAPKLQHQLRDCLTS

Sequences:

>Translated_345_residues
MIQSPTQQASPQTDLKLPKRGLPVTIITGFLGSGKTTLLNHILQDCQDLKVAVLVNEFGDIDIDSQLLVSVEEDMVQLSN
GCICCTINDDLVEAVYSILERNEKVDHLVIETTGVADPLPIALTFAMPPLRNLTQLDSIVTLVDAEAFSPQHFESEAALN
QVSYADIIVLNKTDLAAPQQVDTLEAWVREQKWGARILRSQNSNIPLPLILDTNLFQPERYTAEAKAMAETTHDHHAPHC
HDHHHHSNHLVNDGFVSMAFESDQPFDLDKFQDWLADDLSENVFRAKGFLWFGTITPRYIFQLSGKRYTLDADKWPGIPK
TQLVLIGRELDAPKLQHQLRDCLTS
>Mature_345_residues
MIQSPTQQASPQTDLKLPKRGLPVTIITGFLGSGKTTLLNHILQDCQDLKVAVLVNEFGDIDIDSQLLVSVEEDMVQLSN
GCICCTINDDLVEAVYSILERNEKVDHLVIETTGVADPLPIALTFAMPPLRNLTQLDSIVTLVDAEAFSPQHFESEAALN
QVSYADIIVLNKTDLAAPQQVDTLEAWVREQKWGARILRSQNSNIPLPLILDTNLFQPERYTAEAKAMAETTHDHHAPHC
HDHHHHSNHLVNDGFVSMAFESDQPFDLDKFQDWLADDLSENVFRAKGFLWFGTITPRYIFQLSGKRYTLDADKWPGIPK
TQLVLIGRELDAPKLQHQLRDCLTS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=344, Percent_Identity=31.9767441860465, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI126722884, Length=344, Percent_Identity=31.6860465116279, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI148727351, Length=344, Percent_Identity=31.9767441860465, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI146231952, Length=346, Percent_Identity=31.7919075144509, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223941779, Length=201, Percent_Identity=37.8109452736318, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI223941776, Length=351, Percent_Identity=29.9145299145299, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI119120938, Length=141, Percent_Identity=39.0070921985816, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI87082430, Length=319, Percent_Identity=33.2288401253918, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788499, Length=264, Percent_Identity=30.6818181818182, Blast_Score=101, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324356, Length=240, Percent_Identity=32.9166666666667, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38706; Mature: 38706

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQSPTQQASPQTDLKLPKRGLPVTIITGFLGSGKTTLLNHILQDCQDLKVAVLVNEFGD
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCC
IDIDSQLLVSVEEDMVQLSNGCICCTINDDLVEAVYSILERNEKVDHLVIETTGVADPLP
CCCCHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
IALTFAMPPLRNLTQLDSIVTLVDAEAFSPQHFESEAALNQVSYADIIVLNKTDLAAPQQ
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCH
VDTLEAWVREQKWGARILRSQNSNIPLPLILDTNLFQPERYTAEAKAMAETTHDHHAPHC
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
HDHHHHSNHLVNDGFVSMAFESDQPFDLDKFQDWLADDLSENVFRAKGFLWFGTITPRYI
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEE
FQLSGKRYTLDADKWPGIPKTQLVLIGRELDAPKLQHQLRDCLTS
EEECCCEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIQSPTQQASPQTDLKLPKRGLPVTIITGFLGSGKTTLLNHILQDCQDLKVAVLVNEFGD
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCC
IDIDSQLLVSVEEDMVQLSNGCICCTINDDLVEAVYSILERNEKVDHLVIETTGVADPLP
CCCCHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
IALTFAMPPLRNLTQLDSIVTLVDAEAFSPQHFESEAALNQVSYADIIVLNKTDLAAPQQ
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCH
VDTLEAWVREQKWGARILRSQNSNIPLPLILDTNLFQPERYTAEAKAMAETTHDHHAPHC
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
HDHHHHSNHLVNDGFVSMAFESDQPFDLDKFQDWLADDLSENVFRAKGFLWFGTITPRYI
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEE
FQLSGKRYTLDADKWPGIPKTQLVLIGRELDAPKLQHQLRDCLTS
EEECCCEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]